Vaccines 2011: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry

Date: July 22, 2011
Pages: 180
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Publisher: Kalorama Information
Report type: Strategic Report
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ID: V8075321E9DEN
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Vaccines 2011: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry
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The high growth rates and successful launch of several products recently has kept interest in the global vaccine market high. The global market for vaccines experienced strong growth through 2010 and this is expected to continue through the forecast period. Growth is being fueled by new product introductions and rising usage in all regions.

Kalorama Information has been closely following vaccine markets and since 2003 has instituted a yearly market research report schedule to keep up with fast-moving developments. Our latest comprehensive update, Vaccines 2011: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry, examines the market for vaccines used in humans for various disease. This state-of-the-industry report is a must-have for any executive who wants to stay on top of a rapidly changing market and see what’s expected based on analysis of major company pipelines.

Trends are discussed in this report including the introduction of needle-free systems and the production of vaccines, as well as product safety, supply shortages, and the use of vaccines to prevent pandemics and address bioterrorism, and innovations in vaccine delivery systems. News and reports of vaccine-related illness tend to exacerbate the public’s fears and result in higher rates of non-immunization, and these are discussed in this edition of the report.

The report covers only commercialized vaccines and developmental vaccines for diseases that are already vaccine-preventable; it does not cover emerging vaccines for diseases that are not currently vaccine-preventable. Included in this report are current market size and forecast for the following vaccines:

Pediatric Vaccines:
  • Combinations
  • Hepatitis
  • HIB
  • MMR
  • Pneumococcal
  • Poliovirus
  • Varicella
  • Other Pediatric

Adult Vaccines:
  • Cervical Cancer
  • Hepatitis
  • Influenza
  • Pneumococcal
  • Travel; DT; Misc.

Important trends such as vaccine safety, vaccine shortages, preventing pandemics, vaccines and bioterrorism, DNA vaccination, innovations in vaccine delivery systems and innovations in vaccine Production are covered in the report. Kalorama has expanded the global perspective of this report in this edition, including estimates of vaccine sales (pediatric and adult segments) in the following regions:
  • U.S.
  • Rest of North America
  • South America
  • Europe
  • Japan
  • India
  • China
  • Rest of World
CHAPTER ONE: EXECUTIVE SUMMARY

THE GLOBAL VACCINES INDUSTRY
  Scope and Methodology
  Overview
  Pediatric Preventative Vaccines
The Market
The Market
Total Market
Issues and Trends

CHAPTER TWO: INTRODUCTION TO VACCINES

A Brief History: The Development of Vaccines
The Immune Response
Mechanism of Action
Types of Vaccines
  Attenuated (Weakened) Live Viruses
  Killed (Inactivated) Viruses
  Toxoid Vaccines
  Genetically Engineered/Modified Vaccines
    Subunit Vaccines
    Conjugate Vaccines
    DNA Vaccination
Vaccine Approval Process

CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES

Introduction
Childhood Immunization in the United States
  Childhood Immunization Rates
  Challenges to the Vaccine Delivery System
  The Effect of U.S. Healthcare Reform
  Recommended Childhood Immunization Schedule
  State Immunization Recommendations
  United Nations Initiatives
Pediatric Vaccine Products
  BCG
  Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
    Diphtheria
    Pertussis
    Tetanus
    Hepatitis B
    Poliomyelitis
    Enterotoxigenic Escherichia coli
  Haemophilus Influenzae Type B
  Hepatitis A
  Measles, Mumps and Rubella
    Measles
    Mumps
    Rubella
  Meningococcal Disease
    Parainfluenza Virus Type 3
  Pneumococcal Conjugate
  Rotavirus
    Respiratory Syncytial Virus
  Varicella
Pediatric Vaccines in Development
Cost of Vaccines in the United States
The World Market for Pediatric Preventive Vaccines
  Total Market Size and Forecast
  Hepatitis Vaccine Market
    Market Analysis
    Leading Products and Competitors
  Haemophilus Influenzae Type B Vaccine Market
    Market Analysis
    Leading Products and Competitors
  Measles, Mumps and Rubella Vaccines
    Market Analysis
  Combination Vaccines Market
    Market Analysis
    Leading Products and Competitors
  Pneumococcal Vaccine
    Leading Products and Competitors
  Poliovirus Vaccine
    Market Analysis
    Leading Products and Competitors
  Varicella Vaccines
    Market Analysis
    Leading Products and Competitors
  Other Vaccines Market
    Market Analysis
    Leading Products and Competitors

CHAPTER FOUR: ADULT PREVENTIVE VACCINES

Introduction
Adult Vaccine-Preventable Diseases: Facts and Figures
Global Influenza Surveillance Program
  U.S. Surveillance
Recommendations for Adult Immunizations
  WHO International Health Regulations
Adult Vaccine Products
  Allergies
  Cervical Cancer
  Cholera
  Dengue Fever
  Diphtheria-Tetanus
  Hepatitis
    Hepatitis A
    Hepatitis B
  Influenza
  Japanese Encephalitis
  Malaria
  Pneumococcal Disease
  Rabies
  Shingles
  Typhoid Fever
  Yellow Fever
Adult Vaccines in Development
Total Market Size and Forecast
  Cervical Cancer Market
    Market Analysis
    Leading Products and Competitors
  Hepatitis Market
    Market Analysis
    Leading Products and Competitors
  Influenza Vaccine Market
    Market Analysis
    Leading Products and Competitors
    Market Analysis
    Leading Products and Competitors
  Travel, DT, and Miscellaneous Vaccine Market
    Market Analysis
    Leading Products and Competitors

CHAPTER FIVE: VACCINES MARKET SUMMARY

Trends Driving the Vaccines Market
Market Size and Forecast
  Vaccine Sales by Region
  Vaccine Market Competitors
  Pediatric Vaccines
    Major Manufacturers’ Market Share
  Adult Vaccines
    Major Manufacturers’ Market Share

CHAPTER SIX: ISSUES AND TRENDS

Vaccine Safety
  Refusal to Immunize
  Obesity
  Post-Licensure Surveillance
    Vaccine Adverse Event Reporting System
    The Vaccine Safety Datalink Project
    Phase IV studies
  The Vaccine Injury Compensation Program
    Countermeasures Injury Compensation Program
  World Health Organization
  Other Initiatives
  The Future of Vaccine Safety
Vaccine Shortages
  Preventing Shortages in the Developed Countries
    Financial incentives
    Equitable pricing
    Vaccine stockpiles
  Preventing Shortages in Developing Nations
    Vaccine bonds
Preventing Pandemics
  U.S. National Vaccine Plan
Vaccines and Bioterrorism
  Overview
  Project Bioshield Act
  National Bio and Agro-Defense Facility
  Vaccine Treatment and Evaluation Units
  Anthrax
  Smallpox
  Tularemia
  Viral Hemorrhagic Fevers
DTC Advertising of Vaccines
DNA Vaccination
Innovations in Vaccine Delivery Systems
  Edible Vaccines
  Mucosal Delivery
  Intranasal Delivery
  Vaccine Patches
  Vaccine Chips
Innovations in Vaccine Production
  Tobacco Plants
  Insects
  Nanoparticle Systems
  Cloning

CHAPTER SEVEN: COMPANY PROFILES

AlphaVax, Inc.
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Bavarian Nordic A/S
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Baxter Healthcare
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Bharat Biotech
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Celldex Therapeutics
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Crucell /Johnson & Johnson
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Emergent biosolutions
  History and Lines of Business
  Strategic Acquisition and Alliance
  Vaccine Products
  Financial
GlaxoSmithKline
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Medimmune
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Merck & Co. Inc
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Nabi Biopharmaceuticals
  History and Lines of Business
  Strategic Alliance
  Vaccine Products
  Financial Information
Novartis
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
  History and Lines of Business
  Strategic alliances
  Vaccine Products
  Financial Information
Sanofi Pasteur
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information

COMPANY DIRECTORY

LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Figure 1-1: World Market for Pediatric Vaccines 2005-2014 Revenues
Figure 1-2: World Market for Adult Vaccines 2005-2014 Revenues

CHAPTER TWO: INTRODUCTION TO VACCINES

Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2010
Figure 2-1: Attenuated Virus Production
Table 2-2: Vaccine-Preventable Diseases, June 2011
Table 2-3: VAERS Table of Reportable Events Following Vaccination

CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES

Table 3-1: Global Immunization Rates by Vaccine Type (DPT3, BCG, HepB, Yellow Fever, Tetanus, Hib, MCV, Polio) 2009
Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 1990 - 2009
Table 3-3: U.S. Recommended Immunization Schedule for Children Ages 0 Through 6 Years, 2011
Table 3-4: U.S. Recommended Immunization Schedule for Adolescents Ages 7 to 18 Years, 2011
Table 3-5: Selected Pediatric Vaccines in Development, June 2011
Table 3-6: World Market for Pediatric Vaccines, 2006-2015
Figure 3-1: Market Share of Pediatric Vaccines by Type 2010
Figure 3-2: Market Share of Pediatric Vaccines, by Type 2015
Table 3-7: World Market for Pediatric Vaccines by Region (U.S., Rest of North America, South America, EU, Japan, India, China, Rest of World) 2006-2015 Revenues (in millions)
Table 3-8: World Pediatric Hepatitis Vaccine Market 2006-2015
Table 3-9: World Hib Vaccine Market, 2006-2015
Table 3-10: World MMR Vaccines Market 2006-2015
Table 3-11: World Combination Vaccines Market 2006-2015
Table 3-12: World Pediatric Pneumococcal Vaccine Market 2006-2015
Table 3-13: World Poliovirus Vaccine Market 2006-2015
Table 3-14: World Varicella Vaccine Market 2006-2015
Table 3-15: World Pediatric Other Vaccines Market 2006-2015

CHAPTER FOUR: ADULT PREVENTIVE VACCINES

Table 4-1: Universal Adult Immunization Schedule 2011
Table 4-2: Adult Immunization Schedule for Populations with Special Medical Conditions, 2011
Table 4-3: Initiatives to Require HPV Vaccination by U.S. State, 2011
Table 4-4: WHO Pandemic Classification Schedule
Table 4-5: Selected Adult Preventive Vaccines in Development, 2011
Table 4-6: World Market for Adult Preventive Vaccines, 2006-2015
Figure 4-1: Market Share of Adult Vaccines, by Type, 2010
Figure 4-2: Market Share of Adult Vaccines, by Type, 2015
Table 4-7: World Market for Adult Vaccines by Region (U.S., Rest pf North Amer., South America, EU, Japan, India, China, Rest of World) 2006-2015
Table 4-8: World Cervical CancerVaccine Market 2006-2015
Table 4-9: World Hepatitis Vaccine Market 2006-2015
Table 4-10: World Influenza Vaccine Market 2006-2015
Table 4-11: 2010 Estimated Population by Region (Africa, Asia, Europe, N. America, Oceania, South America) and Selected Age Group (in millions)
Table 4-12: World Pneumococcal Vaccine Market 2006-2015
Table 4-13: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market 2006-2015

CHAPTER FIVE: VACCINES MARKET SUMMARY

Figure 5-1: Sales Growth of Vaccines vs. Pharmaceuticals 2006-2015
Figure 5-2: World Market for Vaccines by Type 2006-2015
Table 5-1: The World Vaccines Market by Vaccine Type 2006-2015
Figure 5-3: World Market for Vaccines Share by Type (Pediatric, Adult), 2006, 2010 and 2015
Table 5-2: The World Vaccines Market by Region (U.S, Rest of North Amer., South America, EU, Japan, India, China, ROW) 2006-2015 Revenues (in millions)
Table 5-3: Major Manufacturers’ Shares of the World Vaccine Market, 2010
Figure 5-3: 2010 World Vaccines Market Share, by Leading Competitors
Table 5-4: Major Manufacturer’s Shares of the World Pediatric Vaccine Market 2010
Figure 5-4: Market Share of Pediatric Vaccines Market, 2010
Table 5-5: Major Manufacturer’s Shares of the World Adult Vaccine Market 2010
Figure 5-5: Market Share of Adult Vaccines Market 2010

CHAPTER SIX: ISSUES AND TRENDS

Table 6-1: Selected Companies/Laboratories Developing Biodefense Vaccines
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