Liquid Chromatography Markets (LC, HPLC and UHPLC)

Date: March 22, 2009
Pages: 178
Price:
US$ 3,500.00
Publisher: Kalorama Information
Report type: Strategic Report
Delivery: E-mail Delivery (PDF)
ID: L7A0D765712EN
Leaflet:

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Liquid Chromatography Markets (LC, HPLC and UHPLC)
The liquid chromatography (LC) market has been relatively mature for quite a while, with a slow evolution of products and applications over the last few decades. High performance liquid chromatography (HPLC) has used essentially the same types of components since the 1980s. However, the market has seen an extraordinary amount of technological change in the last few years as companies have continued to introduce new systems performing fast LC and ultra HPLC (UHPLC).

This report, Liquid Chromatography Markets,, represents Kalorama's most comprehensive look at this dynamic market. This report covers liquid chromatography systems, hardware, software, consumables, and related services, with a focus on HPLC. Both analytical and purification applications are included, but the emphasis leans towards analytical techniques. With quantitative data, a discussion of trends, and expert analysis, the report is perfect for those seeking and understanding of the LC industyr. Included the report is the following:
  • Market Forecasts
  • Overview of the LC Market
  • Product Offerings by Company
  • Breadown of LC Market by Region (US, Europe, Asia, ROW)
  • Detail of Trends and How They Will Impact Market
  • List of Major LC-related Deals since 2003.
  • Company Profiles
  • Details from the HPLC 2008 Convention
  • Seven key Strategic Recommendations for Success in this Market
  • Discussion of the Role of Liquid Chromatography in Food Testing
The research for this report combined a variety of primary and secondary sources. Primary sources included end-users, LC suppliers’ personnel, and other pertinent individuals. Secondary sources included suppliers’ financial statements, websites, journals, trade publications, and other periodicals.

Companies profiled in this report include the following:
  • Agilent Technologies
  • Bio-Rad
  • Dionex
  • Eksigent Technologies
  • ESA Biosciences
  • GE Healthcare
  • Grace Davison Discovery Sciences (W.R. Grace & Co.)
  • Hitachi High Technologies
  • Proxeon Biosystems
  • Shimadzu
  • Thermo Fisher Scientific
  • Varian
  • Waters Corp.
CHAPTER ONE: EXECUTIVE SUMMARY

Applications and Industries
Scope and Methodology

CHAPTER TWO: INTRODUCTION

Background and Definitions
Pumps
Columns
Detectors
Other Accessories and Consumables
Applications and Industries
Scope and Methodology

CHAPTER THREE: MARKET TRENDS

Collaborations, M&A Activity, Regional Expansion
Rise of Diagnostics and Other Clinical Applications
HPLC Spreading Into Niches in Clinical Labs
Advantages and Disadvantages of LC-MS in Clinical Applications
Detection of Doping Agents Using LC-MS
Therapeutic Drug Monitoring of Fentanyl in Urine With LC-MS-MS
Forensic Toxicology Using LC-MS-MS
Discovery and Detection of Genetic Variation by DHPLC
Measuring the Level of Vitamin D in Blood
Increased Global Focus on Food Safety
Introduction
European Union Updates Maximum Residue Levels for Pesticides
Japan Establishes Positive List System
Melamine Contamination of Pet Foods and Dairy
FDA Publishes Laboratory Information Bulletin on Melamine, May 2007
FDA Publishes Laboratory Information Bulletin on Melamine, October 2008
Agilent Technologies Addresses Melamine in Food
Green, Eco-friendly Trends Affecting LC Market
Production Scale LC and Process Analytical LC Gaining Momentum
LC, GC, SFC Applications Blurring
Chiral Separations Gaining Importance
FDA Issues Policy Statements on Chiral Drugs
LC Products for Chiral Separations Proliferate
Hydrophilic Interaction Chromatography (HILIC) Experiencing Rapid Growth
Nano-LC and Nano-electrospray Find Strong Niche Markets
Protein Analysis, Proteomics Driving Market
UHPLC and Fast LC Technology
Shaking Up a Mature Market
Decreasing Particle Size and the van Deemter Curve
UHPLC and Fast LC Product Introductions Stimulate Market
Advances Create Market for New Parts, Consumables, Ancillary Products
Alternative or Intermediate Forms of Fast, Faster LC
Using Standard Pressures for Fast LC
High Temperature LC
Particle Sizes of 2 um to 3 µm
Superficially Porous Particles
Optimizing Extra-Column Volume, Other Paramaters

CHAPTER FOUR: PRODUCTS

Advanced Materials Technology, Inc.
Halo HPLC Columns
Agilent Technologies
1200 Series Rapid Resolution LC (RRLC)
HPLC-Chips
Bio-Rad
Eksigent Technologies
expressHT-Ultra
ESA Biosciences
Corona Charged Aerosol Detector (CAD)
Coulochem and CoulArray Detectors
Hitachi High Technologies
LaChromUltra
Thermo Fisher Scientific
TurboFlow Columns
Varian
920-LC
Waters
Acquity UPLC

CHAPTER FIVE: DEALS


CHAPTER SIX: REVENUES FORECAST AND COMPETITIVE ANALYSIS

Assumptions
Competitive Analysis

CHAPTER SEVEN: CORPORATE PROFILES

Agilent Technologies
Bio-Rad
Dionex
Eksigent Technologies
ESA Biosciences
GE Healthcare
Grace Davison Discovery Sciences (W.R. Grace & Co.)
Hitachi High Technologies
Proxeon Biosystems
Shimadzu
Thermo Fisher Scientific
Varian
Waters Corp.

CHAPTER EIGHT: CHALLENGES AND STRATEGIC RECOMMENDATIONS

Challenges
Advances in Competing Technologies Erode Growth
Clinical Applications Require Adjustment for Companies
Diminishing Returns in Ultra and Fast LC Technologies
Precedence in Purchasing Decisions
Routine Applications Demand Different Types of Systems
Customers’ Experiencing Budget Restrictions or Flat Funding
Customers’ Uncertainty Regarding UHPLC and Fast LC
Strategic Recommendations
Position for Shift Towards Protein Therapeutics
Expand into Related Applications and Products
Incorporate or Enable Green Features
Address Broader Mass Spectometry Adoption
Target Niche Applications Through Differentiation of Products
Strengthen and Emphasize Service and Support
Increase User-Friendliness and Standardization of Software

TABLE OF EXHIBITS


CHAPTER ONE: EXECUTIVE SUMMARY

Table 1-1: Factors Driving Green Initiatives at Labs(Factor, Percent of Respondents)
Figure 1-2: Factors Driving Green Initiatives at Labs (Factor, Percent of Respondents)

CHAPTER THREE: MARKET TRENDS

Table 3-1: Factors Driving Green Initiatives at Labs(Factor, Percent of Respondents)
Figure 3-1: Factors Driving Green Initiatives at Labs (Factor, Percent of Respondents)
Table 3-2: Nano-LC Systems, 2008 (Company, System)
Table 3-3: UHPLC and Fast LC Systems along with Type of Technology and Pressure Limits
Table 3-4: Columns with 2.0 and sub-2 um Totally Porous Particles, 2008
Table 3-5: Columns Designed for High Temperature LC (HTLC)
Table 3-6: Columns with 2 to 3 um Totally Porous Particles, 2008 (Company, Product, Base Material, Stationary Phases, Tmax (C))
Table 3-7: Papers presented at HPLC 2007 and HPLC 2008
Figure 3-2: Application Areas of Papers Presented at HPLC 2007 and 2008
Table 3-8: Particle Size usage, 1997 & 2007
Figure 3-3: Particle Size Usage, 1997 & 2007
Table 3-9: Stationary Phase Used, 2008 (Stationary Phase, Percent of Labs)
Figure 3-4: Stationary Phase Usage in HPLC, 2008 (Stationary Phase, Percent of Labs)
Table 3-10: Stationary Phase Used in RP-HPLC, 2007 (Stationary Phase, Percent of Labs)
Figure 3-4: Stationary Phase Used in Reverse-Phase HPLC, 2007 (Stationary Phase, Percent of Labs)
Table 3-11: Analytical HPLC Mode and Stationary Phase Usage, 2007 (Stationary Phase, Percent of Labs)
Figure 3-5: Analytical HPLC Mode and Stationary Phase Usage, 2007
Table 3-12: Papers Presented at HPLC 2008
Figure 3-6: Detection Techniques Used in Presentations at HPLC 2008
Table 3-13: Number of Sample Injections During Column Life
Figure 3-6: Average Number of Injections During Column Life, 1997 & 2007
Table 3-14: Average Analytical Column Lifetime
Figure 3-7: Average Analytical Column Lifetime, 1997 & 2007
Table 3-15: Sources for HPLC Columns Purchase
Figure 3-8: Sources for HPLC Columns Purchase, 1997 & 2007
Figure 3-9: Top Factors When Selecting HPLC Column Supplier, 2007
Table 3-16: Factors Driving Green Initiatives at Labs
Figure 3-10: Factors Driving Green Initiatives at Laboratories
Table 3-17: Column Developments of Interest in the Future
Figure 3-11: Column Technology Developments of Interest in the Future, 2007
Table 3-18: Anticipated Usage & Impact of UPLC/UHPLC in Next 5-8 Years, 2008
Figure 3-12: Anticipated Usage and Impact of UPLC/UHPLC in Next 5-8 Years, 2008

CHAPTER FOUR: PRODUCTS

Table 4-1: Pressure Necessary for the Halo Column to Achieve Needed Flow Rates
Figure 4-1: The van Deemter Plot of the Fused Core Particles Compared to Other Particles

CHAPTER FIVE: DEALS

Table 5-1 Deals (Company 1, Company 2, Date, Comments)

CHAPTER SIX: REVENUES FORECAST AND COMPETITIVE ANALYSIS

Table 6-1: World LC Market, 2007-2013
Figure 6-1: World Liquid Chromatorgraphy Market Revenues, 2007-2013
Table 6-2: World Liquid Chromatorgraphy Market Revenues, (US, Europe, Asia, Rest of World), 2007-2013
Figure 6-2: World Liquid Chromatorgraphy Market, Growth Rate, 2007-2013
Table 6-3: Top Factors When Selecting HPLC Column Supplier, 2007
Table 6-4: Market Shares of LC Suppliers, 2007
Figure 6-3: Figure 6-3 Market Shares of LC Suppliers, 2007
Figure 6-4: LC Revenues of Leading Suppliers, 2007
Figure 6-5: Waters Corp. Revenues by Quarter, 2002 - 2008
Figure 6-6: Waters Corp. Revenues by Region, 2002 & 2007
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