What's Next In Vaccines (Malaria, Diabetes, Alzheimer's, Allergies and 30 Other Targets in the 2012-2021 Vaccine Pipeline)
Vaccines are one of the most dynamic parts of the pharmaceutical business today but future growth will depend on a considerable amount of potential vaccines in the pipeline.This Kalorama Information report What's Next in Vaccines? examines and estimates the market for vaccines that have yet to be launched. What diseases may see a prophylactics vaccine option in the coming years? Which vaccines will have the most successful business model? Who are the major companies in this market, and possible new entrants? What can current vaccine success stories tell us about the future of the vaccine market? The following target areas are covered in the report:
For each of these areas the report provides Mortality, Severity and Treatment Availability ratings. For marketers and industry watchers a knowledge of all of the potential vaccines will be important to understand how pharma is seeking to renew bottom line with aggressive prophylactic strategies, and who the winners and losers in the near future may be. Kalorama Information has looked at the vaccine market three times in as many years for Kalorama Information, and in this report applies a knowledge of what companies have done in the past to potential efforts.
There are a number of trends that will impact the industry that market watchers will want to know about, and Kalorama Information has covered these trends; including: New Vaccine Technologies, DNA Vaccination, Recent Project Terminations, Innovative Delivery Systems, Edible Vaccines, Vaccine Patches, Funding Shortfalls. The report also discusses vaccine manufacturing methods and the approval process. In addition, the report focuses on the emerging vaccine activities of the following companies
This report provides forecasted revenues for products in development out to 2021. The report does not does not cover indication expansions of existing vaccine products, nor does it cover vaccines for which products currently exist and are widely available, but may need improvement. Development of vaccines that incorporate new production methods (such as the migration of chicken eggs to mammal, yeast or other cells) is also excluded. Cancer vaccines are excluded as Kalorama has an entire report on this topic.
Sales estimates for each market segment represent global revenues and are expressed in current dollars. Information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts’ reports and other sources.
- Acne
- Addiction
- Allergy
- Alzheimer’s Disease
- Anthrax
- Asthma
- Campylobacter Infection
- Chlamydia
- Croup
- Cytomegalovirus (CMV)
- Dengue Fever
- Diabetes
- Ebola
- Epstein-Barr Virus
- Enterotoxigenic Escherichia coli (ETEC)
- Heart Attack
- Helicobacter Pylori
- Hepatitis
- Herpesvirus
- Hookworm
- Hypertension
- HIV/AIDS
- Leishmaniasis
- Malaria
- MRSA Infection
- Multiple Sclerosis
- Obesity
- Parainfluenza Virus Type 3
- Parkinson’s Disease
- Plague
- Ross River Virus
- Shigellosis
- Stroke
- Tuberculosis
- West Nile Virus
For each of these areas the report provides Mortality, Severity and Treatment Availability ratings. For marketers and industry watchers a knowledge of all of the potential vaccines will be important to understand how pharma is seeking to renew bottom line with aggressive prophylactic strategies, and who the winners and losers in the near future may be. Kalorama Information has looked at the vaccine market three times in as many years for Kalorama Information, and in this report applies a knowledge of what companies have done in the past to potential efforts.
There are a number of trends that will impact the industry that market watchers will want to know about, and Kalorama Information has covered these trends; including: New Vaccine Technologies, DNA Vaccination, Recent Project Terminations, Innovative Delivery Systems, Edible Vaccines, Vaccine Patches, Funding Shortfalls. The report also discusses vaccine manufacturing methods and the approval process. In addition, the report focuses on the emerging vaccine activities of the following companies
- Affiris
- Alk-Abello A/S
- Allergy Therapeutics
- AstraZeneca
- Bavarian Nordic A/S
- Baxter Healthcare
- Crucell
- Cytos Biotechnology
- GlaxoSmithKline
- Hawaii Biotech
- Merck & Co. Inc
- Mymetics
- Nabi Biopharmaceuticals
- Novartis
- Opexa Therapeutics
- Sanofi Pasteur
This report provides forecasted revenues for products in development out to 2021. The report does not does not cover indication expansions of existing vaccine products, nor does it cover vaccines for which products currently exist and are widely available, but may need improvement. Development of vaccines that incorporate new production methods (such as the migration of chicken eggs to mammal, yeast or other cells) is also excluded. Cancer vaccines are excluded as Kalorama has an entire report on this topic.
Sales estimates for each market segment represent global revenues and are expressed in current dollars. Information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts’ reports and other sources.
CHAPTER ONE: EXECUTIVE SUMMARY
Emerging Vaccines
Scope and Methodology
Overview
Emerging Vaccines and Forecasts
The Global Market for Emerging Vaccines
CHAPTER TWO: INTRODUCTION TO VACCINES
A Brief History: The Development of Vaccines
The Immune Response
Mechanism of Action
Types of Vaccines
Attenuated (Weakened) Live Viruses
Killed (Inactivated) Viruses
Toxoid Vaccines
Genetically Engineered/Modified Vaccines
Bacteria-Based Vaccines
Vaccine Approval Process
Refusal to Immunize
Expanding Vaccine Availability
Other Trends Driving the Vaccines Market
CHAPTER THREE: EMERGING VACCINES
Introduction
Emerging Vaccines by Disease Area
Acne
Addiction
Allergy
Alzheimer’s Disease
Anthrax
Asthma
Campylobacter Infection
Chlamydia
Croup
Cytomegalovirus (CMV)
Dengue Fever
Diabetes
Ebola
Epstein-Barr Virus
Enterotoxigenic Escherichia coli (ETEC
Heart Attack
Helicobacter Pylori
Hepatitis
Herpesvirus
Hookworm
Hypertension
HIV/AIDS
Leishmaniasis
Malaria
MRSA Infection
Multiple Sclerosis
Obesity
Parainfluenza Virus Type 3
Parkinson’s Disease
Plague
Ross River Virus
Shigellosis
Stroke
Tuberculosis
West Nile Virus
CHAPTER FOUR: EMERGING VACCINES MARKET FORECAST
the Global Market for Emerging Vaccines
Emerging Vaccines Market Segment Forecasts
Acne
Addiction
Allergies
Alzheimer’s Disease
Anthrax
Asthma
Campylobacter Infection
Celiac Disease
Chlamydia
Croup
Diabetes
Ebola
EBV Infection
ETEC Infection
Heart Attack
H. Pylori Infection
Hepatitis C and E
Herpesvirus Infection
Hookworm
Hypertension
HIV/AIDS
Leishmaniasis
Malaria
MRSA Infection
Multiple Sclerosis
Obesity
PIV-3 Infection
Parkinson’s Disease
Plague
RSV Infection
Ross River Virus Infection
Shigellosis
Stroke
Tuberculosis
West Nile Virus
CHAPTER FIVE: ISSUES AND TRENDS
New Vaccine Delivery System
Edible Vaccines
Mucosal Delivery
Intranasal Delivery
Vaccine Patches
Funding Shortfalls
Project Terminations
CHAPTER SIX: COMPANY PROFILES
Affiris
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Alk-Abello A/S
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Allergy Therapeutics
History and Lines of Business
Emerging Vaccine Activities
Financial Information
AstraZeneca
History and Lines of Business
Emerging Vaccine Products
Financial Information
Bavarian Nordic A/S
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Baxter Healthcare
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Crucell
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Cytos Biotechnology
History and Lines of Business
Emerging Vaccine Activities
Financial
GlaxoSmithKline
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Hawaii Biotech
History and Lines of Business
Emerging Vaccine Products
Financial Information
Merck & Co. Inc
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Mymetics
History and Lines of Business
Emerging Vaccine Products
Financial Information
Nabi Biopharmaceuticals
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Novartis
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Opexa Therapeutics
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Sanofi Pasteur
History and Lines of Business
Emerging Vaccine Activities
Financial Information
APPENDIX: COMPANY DIRECTORY
CHAPTER ONE: EXECUTIVE SUMMARY
Table 1-1: Status of Emerging Vaccines by Disease
CHAPTER TWO: INTRODUCTION TO VACCINES
Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2011
Table 2-2: Vaccine-Preventable Diseases, December 2011
Figure 2-1: Attenuated Virus Production
Table 2-3: VAERS Table of Reportable Events Following Vaccination
CHAPTER THREE: EMERGING VACCINES
Figure 3-1: Global Prevalence of Conditions Addressed by Emerging Vaccines, 2012
Figure 3-2: Comparative Mortality, Symptom Severity and Treatment Availability for Conditions Addressed by Emerging Vaccines
Table 3-1: Emerging Vaccines by Disease and Stage of Testing
Figure 3-3: Comparative Severity Ranking of Acne
Figure 3-4: Comparative Severity Ranking of Addiction
Figure 3-5: Comparative Severity Ranking of Allergy
Figure 3-6: Comparative Severity Ranking of Alzheimer’s Disease
Figure 3-7: Comparative Severity Ranking of Anthrax
Figure 3-8: Comparative Severity Ranking of Asthma
Figure 3-9: Comparative Severity Ranking of Campylobacter Infection
Figure 3-10: Comparative Severity Ranking of Celiac Disease
Figure 3-11: Comparative Severity Ranking of Chlamydia
Figure 3-12: Comparative Severity Ranking of Croup
Figure 3-13: Comparative Severity Ranking of Cytomegalovirus
Figure 3-14: Comparative Severity Ranking of Dengue Fever
Figure 3-15: Comparative Severity Ranking of Diabetes
Figure 3-16: Comparative Severity Ranking of Ebola
Figure 3-17: Comparative Severity Ranking of EBV
Figure 3-18: Comparative Severity Ranking of ETEC
Figure 3-19: Comparative Severity Ranking of Heart Attack
Figure 3-20: Comparative Severity Ranking of H. Pylori Infection
Figure 3-21: Comparative Severity Ranking of Hepatitis C and E
Figure 3-22: Comparative Severity Ranking of Herpesvirus Infection
Figure 3-23: Comparative Severity Ranking of Hookworm
Figure 3-24Comparative Severity Ranking of Hypertension
Figure 3-25: Comparative Severity Ranking of HIV/AIDS
Figure 3-26: Comparative Severity Ranking of Leishmaniasis
Figure 3-27: Comparative Severity Ranking of Malaria
Figure 3-28: Comparative Severity Ranking of MRSA Infection
Figure 3-29: Comparative Severity Ranking of Multiple Sclerosis
Figure 3-30: Comparative Severity Ranking of Obesity
Figure 3-31: Comparative Severity Ranking of PIV-3 Infection
Figure 3-32: Comparative Severity Ranking of Parkinson’s Disease
Figure 3-33: Comparative Severity Ranking of Plague
Figure 3-34: Comparative Severity Ranking of RSV Infection
Figure 3-35: Comparative Severity Ranking of Ross River Virus Infection
Figure 3-36: Comparative Severity Ranking of Shigellosis
Figure 3-37: Comparative Severity Ranking of Stroke
Figure 3-38: Comparative Severity Ranking of Tuberculosis
Figure 3-39: Comparative Severity Ranking of West Nile Virus Infection
CHAPTER FOUR: MARKET ANALYSIS
Table 4-1:World Market for Emerging Vaccines by Type, 2011
Table 4-2: World Market for Emerging Vaccines by Type, 2011-2021
Table 4-3: World Acne Vaccine Market 2011-2021
Table 4-4: World Addiction Vaccine Market 2011-2021
Table 4-5: World Allergy Vaccine Market 2011-2021
Table 4-6: World Alzheimer’s Disease Vaccine Market 2011-2021
Table 4-7: World Anthrax Vaccine Market 2011-2021
Table 4-8: World Asthma Vaccine Market 2011-2021
Table 4-9: World Campylobacter Vaccine Market 2011-2021
Table 4-10: World Celiac Disease Vaccine Market 2011-2021
Table 4-11: World Chlamydia Vaccine Market 2011-2021
Table 4-12: World Croup Vaccine Market 2011-2021
Table 4-13: World Cytomegalovirus Vaccine Market 2011-2021
Table 4-14: World Dengue Fever Vaccine Market 2011-2021
Table 4-15: World Diabetes Vaccine Market 2011-2021
Table 4-16: World Ebola Vaccine Market 2011-2021
Table 4-17: World EBV Vaccine Market 2011-2021
Table 4-18: World ETEC Vaccine Market 2011-2021
Table 4-19: World Heart Attack Vaccine Market 2011-2021
Table 4-20: World H. Pylori Vaccine Market 2011-2021
Table 4-21: World Hepatitis C & E Vaccine Market 2011-2021
Table 4-22: World Herpesvirus Vaccine Market 2011-2021
Table 4-23: World Hookworm Vaccine Market 2011-2021
Table 4-24: World Hypertension Vaccine Market 2011-2021
Table 4-25: World HIV/AIDS Vaccine Market 2011-2021
Table 4-26: World Leishmaniasis Vaccine Market 2011-2021
Table 4-27: World Malaria Vaccine Market 2011-2021
Table 4-28: World MRSA Vaccine Market 2011-2021
Table 4-29: World Multiple Sclerosis Vaccine Market 2011-2021
Table 4-30: World Obesity Vaccine Market 2011-2021
Table 4-31: World PIV-3 Vaccine Market 2011-2021
Table 4-32: World Parkinson’s Disease Vaccine Market 2011-2021
Table 4-33: World Plague Vaccine Market 2011-2021
Table 4-34: World RSV Vaccine Market 2011-2021
Table 4-35: World Ross River Virus Vaccine Market 2011-2021
Table 4-36: World Shigellosis Vaccine Market 2011-2021
Table 4-37: World Stroke Vaccine Market 2011-2021
Table 4-38: World Tuberculosis Vaccine Market 2011-2021
Table 4-39: World West Nile Virus Vaccine Market 2011-2021
Emerging Vaccines
Scope and Methodology
Overview
Emerging Vaccines and Forecasts
The Global Market for Emerging Vaccines
CHAPTER TWO: INTRODUCTION TO VACCINES
A Brief History: The Development of Vaccines
The Immune Response
Mechanism of Action
Types of Vaccines
Attenuated (Weakened) Live Viruses
Killed (Inactivated) Viruses
Toxoid Vaccines
Genetically Engineered/Modified Vaccines
Bacteria-Based Vaccines
Vaccine Approval Process
Refusal to Immunize
Expanding Vaccine Availability
Other Trends Driving the Vaccines Market
CHAPTER THREE: EMERGING VACCINES
Introduction
Emerging Vaccines by Disease Area
Acne
Addiction
Allergy
Alzheimer’s Disease
Anthrax
Asthma
Campylobacter Infection
Chlamydia
Croup
Cytomegalovirus (CMV)
Dengue Fever
Diabetes
Ebola
Epstein-Barr Virus
Enterotoxigenic Escherichia coli (ETEC
Heart Attack
Helicobacter Pylori
Hepatitis
Herpesvirus
Hookworm
Hypertension
HIV/AIDS
Leishmaniasis
Malaria
MRSA Infection
Multiple Sclerosis
Obesity
Parainfluenza Virus Type 3
Parkinson’s Disease
Plague
Ross River Virus
Shigellosis
Stroke
Tuberculosis
West Nile Virus
CHAPTER FOUR: EMERGING VACCINES MARKET FORECAST
the Global Market for Emerging Vaccines
Emerging Vaccines Market Segment Forecasts
Acne
Addiction
Allergies
Alzheimer’s Disease
Anthrax
Asthma
Campylobacter Infection
Celiac Disease
Chlamydia
Croup
Diabetes
Ebola
EBV Infection
ETEC Infection
Heart Attack
H. Pylori Infection
Hepatitis C and E
Herpesvirus Infection
Hookworm
Hypertension
HIV/AIDS
Leishmaniasis
Malaria
MRSA Infection
Multiple Sclerosis
Obesity
PIV-3 Infection
Parkinson’s Disease
Plague
RSV Infection
Ross River Virus Infection
Shigellosis
Stroke
Tuberculosis
West Nile Virus
CHAPTER FIVE: ISSUES AND TRENDS
New Vaccine Delivery System
Edible Vaccines
Mucosal Delivery
Intranasal Delivery
Vaccine Patches
Funding Shortfalls
Project Terminations
CHAPTER SIX: COMPANY PROFILES
Affiris
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Alk-Abello A/S
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Allergy Therapeutics
History and Lines of Business
Emerging Vaccine Activities
Financial Information
AstraZeneca
History and Lines of Business
Emerging Vaccine Products
Financial Information
Bavarian Nordic A/S
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Baxter Healthcare
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Crucell
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Cytos Biotechnology
History and Lines of Business
Emerging Vaccine Activities
Financial
GlaxoSmithKline
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Hawaii Biotech
History and Lines of Business
Emerging Vaccine Products
Financial Information
Merck & Co. Inc
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Mymetics
History and Lines of Business
Emerging Vaccine Products
Financial Information
Nabi Biopharmaceuticals
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Novartis
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Opexa Therapeutics
History and Lines of Business
Emerging Vaccine Activities
Financial Information
Sanofi Pasteur
History and Lines of Business
Emerging Vaccine Activities
Financial Information
APPENDIX: COMPANY DIRECTORY
CHAPTER ONE: EXECUTIVE SUMMARY
Table 1-1: Status of Emerging Vaccines by Disease
CHAPTER TWO: INTRODUCTION TO VACCINES
Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2011
Table 2-2: Vaccine-Preventable Diseases, December 2011
Figure 2-1: Attenuated Virus Production
Table 2-3: VAERS Table of Reportable Events Following Vaccination
CHAPTER THREE: EMERGING VACCINES
Figure 3-1: Global Prevalence of Conditions Addressed by Emerging Vaccines, 2012
Figure 3-2: Comparative Mortality, Symptom Severity and Treatment Availability for Conditions Addressed by Emerging Vaccines
Table 3-1: Emerging Vaccines by Disease and Stage of Testing
Figure 3-3: Comparative Severity Ranking of Acne
Figure 3-4: Comparative Severity Ranking of Addiction
Figure 3-5: Comparative Severity Ranking of Allergy
Figure 3-6: Comparative Severity Ranking of Alzheimer’s Disease
Figure 3-7: Comparative Severity Ranking of Anthrax
Figure 3-8: Comparative Severity Ranking of Asthma
Figure 3-9: Comparative Severity Ranking of Campylobacter Infection
Figure 3-10: Comparative Severity Ranking of Celiac Disease
Figure 3-11: Comparative Severity Ranking of Chlamydia
Figure 3-12: Comparative Severity Ranking of Croup
Figure 3-13: Comparative Severity Ranking of Cytomegalovirus
Figure 3-14: Comparative Severity Ranking of Dengue Fever
Figure 3-15: Comparative Severity Ranking of Diabetes
Figure 3-16: Comparative Severity Ranking of Ebola
Figure 3-17: Comparative Severity Ranking of EBV
Figure 3-18: Comparative Severity Ranking of ETEC
Figure 3-19: Comparative Severity Ranking of Heart Attack
Figure 3-20: Comparative Severity Ranking of H. Pylori Infection
Figure 3-21: Comparative Severity Ranking of Hepatitis C and E
Figure 3-22: Comparative Severity Ranking of Herpesvirus Infection
Figure 3-23: Comparative Severity Ranking of Hookworm
Figure 3-24Comparative Severity Ranking of Hypertension
Figure 3-25: Comparative Severity Ranking of HIV/AIDS
Figure 3-26: Comparative Severity Ranking of Leishmaniasis
Figure 3-27: Comparative Severity Ranking of Malaria
Figure 3-28: Comparative Severity Ranking of MRSA Infection
Figure 3-29: Comparative Severity Ranking of Multiple Sclerosis
Figure 3-30: Comparative Severity Ranking of Obesity
Figure 3-31: Comparative Severity Ranking of PIV-3 Infection
Figure 3-32: Comparative Severity Ranking of Parkinson’s Disease
Figure 3-33: Comparative Severity Ranking of Plague
Figure 3-34: Comparative Severity Ranking of RSV Infection
Figure 3-35: Comparative Severity Ranking of Ross River Virus Infection
Figure 3-36: Comparative Severity Ranking of Shigellosis
Figure 3-37: Comparative Severity Ranking of Stroke
Figure 3-38: Comparative Severity Ranking of Tuberculosis
Figure 3-39: Comparative Severity Ranking of West Nile Virus Infection
CHAPTER FOUR: MARKET ANALYSIS
Table 4-1:World Market for Emerging Vaccines by Type, 2011
Table 4-2: World Market for Emerging Vaccines by Type, 2011-2021
Table 4-3: World Acne Vaccine Market 2011-2021
Table 4-4: World Addiction Vaccine Market 2011-2021
Table 4-5: World Allergy Vaccine Market 2011-2021
Table 4-6: World Alzheimer’s Disease Vaccine Market 2011-2021
Table 4-7: World Anthrax Vaccine Market 2011-2021
Table 4-8: World Asthma Vaccine Market 2011-2021
Table 4-9: World Campylobacter Vaccine Market 2011-2021
Table 4-10: World Celiac Disease Vaccine Market 2011-2021
Table 4-11: World Chlamydia Vaccine Market 2011-2021
Table 4-12: World Croup Vaccine Market 2011-2021
Table 4-13: World Cytomegalovirus Vaccine Market 2011-2021
Table 4-14: World Dengue Fever Vaccine Market 2011-2021
Table 4-15: World Diabetes Vaccine Market 2011-2021
Table 4-16: World Ebola Vaccine Market 2011-2021
Table 4-17: World EBV Vaccine Market 2011-2021
Table 4-18: World ETEC Vaccine Market 2011-2021
Table 4-19: World Heart Attack Vaccine Market 2011-2021
Table 4-20: World H. Pylori Vaccine Market 2011-2021
Table 4-21: World Hepatitis C & E Vaccine Market 2011-2021
Table 4-22: World Herpesvirus Vaccine Market 2011-2021
Table 4-23: World Hookworm Vaccine Market 2011-2021
Table 4-24: World Hypertension Vaccine Market 2011-2021
Table 4-25: World HIV/AIDS Vaccine Market 2011-2021
Table 4-26: World Leishmaniasis Vaccine Market 2011-2021
Table 4-27: World Malaria Vaccine Market 2011-2021
Table 4-28: World MRSA Vaccine Market 2011-2021
Table 4-29: World Multiple Sclerosis Vaccine Market 2011-2021
Table 4-30: World Obesity Vaccine Market 2011-2021
Table 4-31: World PIV-3 Vaccine Market 2011-2021
Table 4-32: World Parkinson’s Disease Vaccine Market 2011-2021
Table 4-33: World Plague Vaccine Market 2011-2021
Table 4-34: World RSV Vaccine Market 2011-2021
Table 4-35: World Ross River Virus Vaccine Market 2011-2021
Table 4-36: World Shigellosis Vaccine Market 2011-2021
Table 4-37: World Stroke Vaccine Market 2011-2021
Table 4-38: World Tuberculosis Vaccine Market 2011-2021
Table 4-39: World West Nile Virus Vaccine Market 2011-2021
