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Global Human Growth Hormone Market Report: 2012 Edition

September 2012 | 42 pages | ID: G986F345784EN
Koncept Analytics

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Pituitary- the master gland of human body is responsible for controlling crucial hormonal secretion which in turn regulates other key aspects of human body such as temperature, growth, thyroid functioning, urination and production of other hormones. It is a pea sized gland situated at the base of brain and is a major component of human body as it expedites the response towards the surrounding environment and settings.

Any deformity or damage to the pituitary gland can adversely impact the production and activity level of the above mentioned hormones thereby affecting the body work process and stunting the outcomes especially in the case of growth hormone. Marred pituitary function leads to either over or under secretion of the somatrpopin that is the growth hormone. Its over secretion causes disfiguration in the body parts like hands, face, feet etc. whereas its deficiency impedes the growth of body parts/whole body thus leading to disease states like dwarfism or gigantism.

It is observed that the growth hormone related problems usually affect children and teenagers, but it is seen to grip adults as well but to a lesser extent. The major factors which vitiate the pituitary operations thus impairing the GH role include kidney malfunction, tumors/cancer especially associated with brain. There are some other unknown causes as well which are termed as idiopathic. Earlier, to deal with these predicaments, growth hormone (GH) used to be extracted from the human cadavers but, as time passed and evolution of technology/tools/techniques/R&D took place, the extraction of GH also got altered and many novel innovations and discoveries were made in the respective field.

Now a days, many leading companies are heavily involved in the R&D process for devising longer acting and sustained release versions of the somatropin which are produced using the recombinant technology. The competition prevalent in the respective industry is heating up day by day. The human growth hormone market (HGH) is monopolized by a few players viz. Pfizer, NovoNordisk, Eli Lilly and Roche.

The global HGH report discusses the key ongoing trends like licensing agreement, development of needle free injectors and comparison between generic and biosimilar drug versions. On the industry development front, the current inclination is towards creating innovative therapeutic products with novel properties. Furthermore, the major factors driving the HGH market include rising cancer and CKD/ESRD cases and increasing GNI and healthcare expenditure on worldwide basis. In addition, a few factors posing challenges in front of the HGH industry are the off-label HGH use, associated risks and side effects and the escalating price pressure which, to an extent, are hindering the growth and development of the same.

By combining SPSS Inc.’s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of the industry. We employed various significant variables that have an impact on this industry and created regression models with SPSS Base to determine the future direction of the industry. Before deploying the regression model, the relationship between several independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables and tests.
1. HUMAN GROWTH HORMONE

1.1 Physiological Effects of Growth Hormone
1.2 GH Secretion Control
1.3 GH Deficiency (GHD)
  1.3.1 Disease States
1.4 Therapeutic and Other Uses of GH/HGH
1.5 Recombinant Human Growth Hormone (rHGH)

2. GLOBAL HGH MARKET SIZE

  Market Value
  Market Share
2.1 HGH-CTP Market Opportunity Model
2.2 SRhGH Market Opportunity Model

3. MARKET DYNAMICS

3.1 Key Trends
  3.1.1 Strategic Agreements
  3.1.2 Inclination towards Needle-Free Injectors
  3.1.3 Generic Vs Biosimilar Version of the drugs
3.2 Industry Developments
  3.2.1 New Products under Development
3.3 Growth Drivers
  3.3.1 Increasing Prevalence of Cancer
  3.3.2 Increasing Cases Chronic Kidney Disease (CKD)
  3.3.3 Rising Healthcare Expenditure
  3.3.4 Increasing Global GNI (Gross National Income)
3.4 Challenges
  3.4.1 Unapproved/off-label Uses of HGH
  3.4.2 Possible Side Effects and other Associated Risks
  3.4.3 Escalating Price Pressure

4. COMPETITIVE LANDSCAPE

Competitive Overview
Market Share

5. COMPANY PROFILES

5.1 Roche Holdings AG
  Business Overview
  Financial Overview
  Business Strategies
  Focus On Innovative Pharmaceuticals
  Leverage Expertise in Molecular Biology
5.2 Novo Nordisk
  Business Overview
  Financial Overview
  Business Strategies
  Focus on Hormone Therapy
  Leadership in Hemophilia Treatment
5.3 Pfizer, Inc.
  Business Overview
  Financial Overview
  Business Strategies
  Focus on Growth
  Strategic Acquisitions
5.4 Eli Lilly and Company
  Business Overview
  Financial Overview
  Business Strategies
  Focus on Novel Therapeutic Molecules
  Capacity Expansion

6. MARKET OUTLOOK

6.1 Market Forecast
6.2 Forecast Methodology
  6.2.1 Dependent and Independent Variables
  6.2.2 Correlation Analysis
  6.2.3 Regression Analysis

LIST OF CHARTS

GH’s Physiological Effect
GH Secretion Control
Global HGH Market Share (2010)
Global Human Growth Hormone Market (2004-2010)
Global hGH-CTP Market Opportunity (2014E-2020E)
Market Share of Chemical Drugs and Biologics as per Drug Versions
Number of Cancer Cases Worldwide (2007-2011)
Worldwide Patients with End Stage Renal Disease (2005-2011)
Global Healthcare Spending (2005-2015E)
World Gross National Income (2005-2010)
Growth Hormone Volume Market share (February 2007-February 2012)
Roche’s Revenues by Business Segments (2011)
Roche’s Revenues and Net Income, 2007-2011
Novo Nordisk Revenue Share by Business Segments (2011)
Novo Nordisk Revenues & Net Income (2008-2011)
Pfizer’s Revenue Share by Business Segments (2011)
Pfizer’s Revenues & Net Income (2008-2011)
Eli Lilly’s Revenues by Segment (2011)
Eli Lilly’s Revenue and Net Income (2008-2011)
Global HGH Market Forecast (2009-2014E)

LIST OF TABLES

Worldwide Revenues of Marketed hGH Products (2011)
hGH-CTP US Market Opportunity Model (2014E-2020E)
hGH-CTP European Market Opportunity Model (2014E-2020E)
SRhGH Market Opportunity Model (2013E-2020E)
Annual US Sales of rHGH and Injectors
LG Life Sciences Product under Development
Sustained-release HGH under Development Worldwide
Prolor’s Product under Development
GH Products Devised by NovoNordisk
Growth Hormone Volume Market share (February 2007-February 2012)
Dependent & Independent Variables (2006-2011)
Correlation Matrix
Model Summary – Coefficient of Determination
Regression Coefficients Output


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