MicroRNAs and Exosomes Market Report 2012

July 2012 | 168 pages | ID: M7E53AF2A38EN
Select Biosciences Ltd.

Abstracts

This is the latest and most up-to-date Market Report from Select Biosciences addressing the microRNA and Exosomes markets as they are evolving. In this report, we focus upon the microRNA research marketplace from the perspective of the translational opportunities in these spaces. The focus of this field is moving from basic research towards the utility of associations of microRNA expression patterns in disease. In this manner, microRNA signatures may be validated as biomarkers in many disease areas—cancers, cardiovascular disease, neurological disease, inflammation, and metabolic diseases.

• Select Biosciences has performed worldwide market tracking wherein we’ve analyzed end-user research trends in the microRNA as well as Exosome markets—these areas are evolving in parallel given the opportunity in the Circulating Biomarkers space and the utility of microRNAs and mRNAs to be harvested from exosomes and assayed as signatures for disease.
• For exosomes, we’ve analyzed the research trends, types of downstream applications being performed as well as biomarker classes being studied currently and this is the First Market Report to Document the Market Landscape of Exosomes.

Select Biosciences has characterized the associations of microRNAs in various disease classes and presents these detailed associations as “hotspot maps” in this report. Specifically, these associations [to be interpreted as starting material for biomarker development and validation] are described for many cancer classes, cardiovascular disease, CNS disease, diabetes, inflammation, and obesity. They offer the opportunity for R&D planning efforts addressing the question of “which microRNA content needs to be addressed in a particular disease class.”

This data-driven characterization of the microRNAs and Exosomes landscape is a hands-on document that can be used for competitive benchmarking, business planning, and strategy development—all the data that have been collected in this industry analysis are presented and they form the basis for the conclusions drawn throughout the market report presented in a format enabling “drag-and-drop” into business presentations/business plans—this Market Report is written and delivered to customers in PowerPoint format.

Extensive Technical and Market Analyses

Presented in this Report

• MicroRNA Research Market Analysis
• Research Market Size and Growth Rate
• Grant Funding Metrics
• Qualitative and Quantitative Research Market Trends
• Segmentation of Research Activities
• Market Penetrance of Product Vendors into the microRNA Research Market
• Unmet Needs
• Association of microRNA Expression Patterns in Various Disease Classes
• Various Types of Cancer: Breast Cancer, Lung Cancer, Prostate Cancer, Pancreatic Cancer, GI Tract Cancers, Hematological Malignancies
• Muscular Development and Cardiovascular Disease
• CNS Disease
• Metabolic Disease, Diabetes
• Stem Cells
• Liver Disease, Liver Toxicity
• Exosomes Marketplace
• Nature and Categorization
• Current Research Trends based on Primary Market Survey
• Downstream Applications
• Circulating Biomarkers
• Utility of microRNA Signatures
• microRNA Signatures in Specific Cancers Characterized in Biological Fluids to Date

Contents

CHAPTER I. MICRORNA RESEARCH MARKET ANALYSIS

Scope
Segmentation of the RNA Space
MicroRNA genes, non-coding RNA genes
Primary Market Survey to Assess microRNA Research Trends
  Qualitative and Quantitative Market Data
MicroRNA Grant Funding Metrics in the US
miRBase Registry Metrics
MicroRNA Research Market Size and Growth Rate
Heat Map of microRNA Research and its Evolution
  Detailed Analysis of microRNA-Focused Publications as a Means to Segment the Space
Expansion of the microRNA Field
MicroRNA Association Documented in Various Disease Classes:
Potential for Development into Biomarkers
Translational Value of microRNA Associations
The Potential for Long Non-coding RNAs
Long Non-coding RNAs Market Trends

CHAPTER II. MICRORNAS IN PHYSIOLOGICAL AND DISEASE PROCESSES

Cancer
microRNAs Documented in Chromosomal Alterations/Aberrations
Epigenetic Silencing of microRNAs
microRNA Expression Profiles in Hematological Malignancies
microRNA Expression Profiles in Solid Tumors
microRNAs Associated with Outcome in Cancers [Cancer Personalized Medicine]
microRNAs in Breast Cancer
microRNAs in Lung Cancer
microRNAs in Prostate Cancer
microRNAs in Pancreatic Cancer
microRNAs in GI Tract Cancers
Normal Muscle Development and Vascular Disease
  microRNAs Associated with Vascular Disease, Inflammation and Angiogenesis
  microRNAs Associated with Cardiac Hypertrophy Diabetes
CNS Normal Development and Diseases
Stem Cells
Hepatic Physiology, Pathology, and Toxicity Screening

CHAPTER III. EXOSOMES MARKET ANALYSIS

Exosomes Characteristics
Exosomes Market Trends
  Quantitative Analysis of Research Market Trends
  Worldwide Market Survey Data and Trends Therein
Emerging Space of Circulating Biomarkers
  Sources of Circulating Nucleic Acids
  Plasma microRNAs as Candidate Biomarkers in Various Disease Classes
  Signatures of Circulating Cell-Free microRNAs in Various Cancer Classes
  Comparison of Various Classes of Biomarkers

APPENDIX. RESEARCH METHODOLOGY