Epigenetics Market Trends 2011
This is the latest and most up-to-date Market Report from Select Biosciences addressing the expanding epigenetics marketplace. Epigenetics research efforts are growing around the world driven by the numerous documented associations of epigenetic modifications with diseases—especially various types of cancers.
This report presents the biological role of various epigenetic modifications in vivo and frames them in the context of specific biological events such as differentiation and disease.
This report also examines qualitative and in quantitative terms the research market landscape of epigenetics as it exists currently based on Select Biosciences bottom-up market research on this topic. Presented is market segmentation of epigenetics based on end-user research, based on technology utilization, and based on specific disease areas being studied. The primary market data are derived from a worldwide respondent pool that is highly-representative of the life science research community and therefore provides an excellent proxy for the understanding of the research trends operative in this space.
In addition to characterization of the epigenetics research marketplace, this report also presents an analysis of epigenetic biomarkers and their deployment as potential diagnostics. Also presented herein are the efforts vis-à-vis deployment of epigenetics as therapeutics—in this vein the clinical pipeline as it exists currently is presented.
This data-driven characterization of the epigenetics research landscape is a hands-on document that can be used for competitive benchmarking, business planning, and strategy development—all the data that have been collected in this industry analysis are presented and they form the basis for the conclusions drawn throughout the market report presented in a format enabling “drag-and-drop” into business presentations/business plans.
Extensive Worldwide Technical and Market Analyses Presented in this Report:
This report presents the biological role of various epigenetic modifications in vivo and frames them in the context of specific biological events such as differentiation and disease.
This report also examines qualitative and in quantitative terms the research market landscape of epigenetics as it exists currently based on Select Biosciences bottom-up market research on this topic. Presented is market segmentation of epigenetics based on end-user research, based on technology utilization, and based on specific disease areas being studied. The primary market data are derived from a worldwide respondent pool that is highly-representative of the life science research community and therefore provides an excellent proxy for the understanding of the research trends operative in this space.
In addition to characterization of the epigenetics research marketplace, this report also presents an analysis of epigenetic biomarkers and their deployment as potential diagnostics. Also presented herein are the efforts vis-à-vis deployment of epigenetics as therapeutics—in this vein the clinical pipeline as it exists currently is presented.
This data-driven characterization of the epigenetics research landscape is a hands-on document that can be used for competitive benchmarking, business planning, and strategy development—all the data that have been collected in this industry analysis are presented and they form the basis for the conclusions drawn throughout the market report presented in a format enabling “drag-and-drop” into business presentations/business plans.
Extensive Worldwide Technical and Market Analyses Presented in this Report:
- Characterization of Epigenetics Modifications
- DNA Methylation, the Various Histone Modifications and their Qualitative Effects In Vivo
- Epigenetic Silencing of Genes and Pathways: Mechanism and Effects
- Tumor Suppressor Genes Silenced In Vivo
- Specific Genes Modulated via Epigenetics In Various Diseases
- Market Segmentation of Epigenetics by Disease Class
- Epigenetics Market Segmentation
- Epigenetics Market Segmentation by End-User Research Penetrance
- Epigenetics Market Quantitative Segmentation by type of Modification Studied
- Epigenetics Market Segmentation by Type of HDAC Studied
- Penetrance of Product Vendors into Various Segments of the Epigenetics Marketplace: Quantitative Analysis
- Emerging Trends and Themes in Epigenetics
- Current Studies of microRNAs, non-coding RNAs, and Tumor Suppressor Genes in the Epigenetics Marketplace
- Epigenetics-based Diagnostics: Epigenetics-based Biomarkers and their Current Status
- Epigenetics-based Therapeutics: The current Clinical Pipeline of Approved and In-Development Therapeutics
- More details of the scope of coverage of this industry report are found in the Table of Contents (TOC) for the report—see below for link to downloadable PDF of the TOC
CHAPTER I. EXECUTIVE OVERVIEW
CHAPTER II. EPIGENETICS: BIOLOGICAL ALTERATIONS & IMPLICATIONS
Epigenetics: An Emerging Market Space
Mechanisms and Consequences of Epigenetic Modifications
The Various Chromatin Modifications: Transcriptional
Activation or Silencing of Genes
DNA Methylation-based Silencing
Cellular Pathways Disrupted by Epigenetic Silencing
Histone Modifications and HDACs
Epigenetic Modifications and Their Impact
Epigenetic Aberrations in Various Diseases (CNS, Cancers)
CHAPTER III. EPIGENETICS RESEARCH MARKET TRENDS
The Research Marketplace
Epigenetics Market Segmentation by End-Users
DNMT Market Segmentation by End-Users
HDAC Market Segmentation by End-Users
Epigenetics Market Segmentation based on Research Technologies
Penetration of Research Product Vendors into Epigenetic Market Segments
Emerging Trends in Epigenetics Research
Large ncRNAs, microRNAs, and Tumor Suppressors in Epigenetics
Epigenetics Market Quantification
CHAPTER IV. EPIGENETICS DIAGNOSTICS & THERAPEUTICS TRENDS
Applications of Epigenetic Signatures
Epigenetics Biomarker Classes
Genomic Imprinting
Genes Methylated in Cancer with Potential as Cancer Biomarkers
Companies Developing Epigenetics-based Diagnostics
Recent Clinical Trials with DNA Methylation Inhibitors
Epigenetic Therapies Under Development Currently: Pipeline
Companies Pursuing Epigenetic Therapeutics
APPENDIX I. RESEARCH METHODOLOGY
CHAPTER II. EPIGENETICS: BIOLOGICAL ALTERATIONS & IMPLICATIONS
Epigenetics: An Emerging Market Space
Mechanisms and Consequences of Epigenetic Modifications
The Various Chromatin Modifications: Transcriptional
Activation or Silencing of Genes
DNA Methylation-based Silencing
Cellular Pathways Disrupted by Epigenetic Silencing
Histone Modifications and HDACs
Epigenetic Modifications and Their Impact
Epigenetic Aberrations in Various Diseases (CNS, Cancers)
CHAPTER III. EPIGENETICS RESEARCH MARKET TRENDS
The Research Marketplace
Epigenetics Market Segmentation by End-Users
DNMT Market Segmentation by End-Users
HDAC Market Segmentation by End-Users
Epigenetics Market Segmentation based on Research Technologies
Penetration of Research Product Vendors into Epigenetic Market Segments
Emerging Trends in Epigenetics Research
Large ncRNAs, microRNAs, and Tumor Suppressors in Epigenetics
Epigenetics Market Quantification
CHAPTER IV. EPIGENETICS DIAGNOSTICS & THERAPEUTICS TRENDS
Applications of Epigenetic Signatures
Epigenetics Biomarker Classes
Genomic Imprinting
Genes Methylated in Cancer with Potential as Cancer Biomarkers
Companies Developing Epigenetics-based Diagnostics
Recent Clinical Trials with DNA Methylation Inhibitors
Epigenetic Therapies Under Development Currently: Pipeline
Companies Pursuing Epigenetic Therapeutics
APPENDIX I. RESEARCH METHODOLOGY
