Cystic Fibrosis Therapeutics Global Market Insights 2025, Analysis and Forecast to 2030, by Market Participants, Regions, Technology, Application, Product Type

May 2025 | 92 pages | ID: CD947B1FA8DAEN
Prof Research

Abstracts

Cystic Fibrosis Therapeutics Market Summary

Introduction and Market Overview

Cystic fibrosis (CF) therapeutics, including CFTR modulators, pancreatic enzyme supplements, mucolytics, and bronchodilators, address a genetic disorder affecting approximately 105,000 patients globally, with 40,000 in the U.S. and 50,000 in Europe. The market is driven by rising diagnosis rates, with newborn screening increasing detection by 20%, and transformative CFTR modulators like Trikafta, which improve lung function in 90% of F508del patients and reduce hospitalizations by 60%. Early intervention, extended patient lifespans (30% higher survival with early treatment), and supportive policies, with 60% of OECD countries covering CFTR modulators, fuel demand. The global CF therapeutics market is estimated at USD 6.0-10.0 billion in 2025, with a CAGR of 11%-16% through 2030.

Regional Market Trends

• North America: The U.S. leads with widespread newborn screening and Trikafta adoption, while Canada emphasizes CF care access.
• Europe: The UK, Germany, and France drive growth with robust reimbursement for CFTR modulators.
• Asia Pacific: Australia expands CF screening, while Japan focuses on novel therapies.
• Rest of the World: Brazil improves CF care infrastructure, while the Middle East addresses genetic screening.

Distribution Channel Analysis

• Hospital Pharmacies: Expected growth of 11.5%-16.5%, driven by CFTR modulator prescriptions. Trends focus on specialized care.
• Online Pharmacies: Projected growth of 12.0%-17.0%, linked to patient convenience. Advances emphasize digital access.
• Retail Pharmacies: Anticipated growth of 10.5%-15.5%, covering supportive therapies. Trends highlight community-based care.

Type Analysis

• CFTR Modulators: Expected growth of 12.0%-17.0%, valued for transformative outcomes. Trends focus on triple-combination therapies like Vanza.
• Pancreatic Enzyme Supplements: Projected growth of 10.5%-15.5%, essential for digestion. Advances emphasize high-potency formulations.
• Mucolytics: Anticipated growth of 10.0%-15.0%, used for airway clearance. Trends highlight inhalation therapies.
• Bronchodilators: Expected growth of 9.5%-14.5%, suited for symptom relief. Developments prioritize long-acting agents.

Key Market Players

• Vertex Pharmaceuticals: Pioneers CFTR modulators like Trikafta.
• AbbVie: Develops pancreatic enzyme supplements.
• Gilead: Focuses on CF supportive therapies.
• Roche: Provides mucolytics for airway management.
• Sionna Therapeutics: Innovates novel CFTR therapies.

Porter’s Five Forces Analysis

• Threat of New Entrants: Low, due to high R&D costs and regulatory barriers for orphan drugs.
• Threat of Substitutes: Low, as CFTR modulators are unique, though gene therapies pose future competition.
• Bargaining Power of Buyers: Moderate, with insurers negotiating prices, but limited alternatives strengthen providers.
• Bargaining Power of Suppliers: Low, with multiple manufacturers of APIs.
• Competitive Rivalry: Moderate, with Vertex dominating, but emerging players challenge with novel therapies.

Market Opportunities and Challenges

Opportunities:

• Addressing 105,000 CF patients globally.
• Leveraging CFTR modulators, improving outcomes for 90% of F508del patients.
• Utilizing newborn screening, increasing diagnosis by 20%.
• Supporting early intervention, raising survival by 30%.
• Benefiting from 60% OECD reimbursement coverage.
• Expanding research funding, like CFF’s USD 6.6 million investment.

Challenges:

• High costs of CFTR modulators limiting access.
• Regulatory delays for novel therapies.
• Limited CF infrastructure in developing regions.
• Competition from emerging gene therapies.
• Patient adherence issues with complex regimens.

Contents

CHAPTER 1 EXECUTIVE SUMMARY

CHAPTER 2 ABBREVIATION AND ACRONYMS

CHAPTER 3 PREFACE

3.1 Research Scope
3.2 Research Sources
  3.2.1 Data Sources
  3.2.2 Assumptions
3.3 Research Method
Chapter Four Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users

CHAPTER 5 MARKET TREND ANALYSIS

5.1 Introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats

CHAPTER 6 INDUSTRY CHAIN ANALYSIS

6.1 Upstream/Suppliers Analysis
6.2 Cystic Fibrosis Therapeutics Analysis
  6.2.1 Technology Analysis
  6.2.2 Cost Analysis
  6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users

CHAPTER 7 LATEST MARKET DYNAMICS

7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics

CHAPTER 8 HISTORICAL AND FORECAST CYSTIC FIBROSIS THERAPEUTICS MARKET IN NORTH AMERICA (2020-2030)

8.1 Cystic Fibrosis Therapeutics Market Size
8.2 Cystic Fibrosis Therapeutics Market by End Use
8.3 Competition by Players/Suppliers
8.4 Cystic Fibrosis Therapeutics Market Size by Type
8.5 Key Countries Analysis
  8.5.1 United States
  8.5.2 Canada
  8.5.3 Mexico

CHAPTER 9 HISTORICAL AND FORECAST CYSTIC FIBROSIS THERAPEUTICS MARKET IN SOUTH AMERICA (2020-2030)

9.1 Cystic Fibrosis Therapeutics Market Size
9.2 Cystic Fibrosis Therapeutics Market by End Use
9.3 Competition by Players/Suppliers
9.4 Cystic Fibrosis Therapeutics Market Size by Type
9.5 Key Countries Analysis
  9.5.1 Brazil
  9.5.2 Argentina
  9.5.3 Chile
  9.5.4 Peru

CHAPTER 10 HISTORICAL AND FORECAST CYSTIC FIBROSIS THERAPEUTICS MARKET IN ASIA & PACIFIC (2020-2030)

10.1 Cystic Fibrosis Therapeutics Market Size
10.2 Cystic Fibrosis Therapeutics Market by End Use
10.3 Competition by Players/Suppliers
10.4 Cystic Fibrosis Therapeutics Market Size by Type
10.5 Key Countries Analysis
  10.5.1 China
  10.5.2 India
  10.5.3 Japan
  10.5.4 South Korea
  10.5.5 Southest Asia
  10.5.6 Australia

CHAPTER 11 HISTORICAL AND FORECAST CYSTIC FIBROSIS THERAPEUTICS MARKET IN EUROPE (2020-2030)

11.1 Cystic Fibrosis Therapeutics Market Size
11.2 Cystic Fibrosis Therapeutics Market by End Use
11.3 Competition by Players/Suppliers
11.4 Cystic Fibrosis Therapeutics Market Size by Type
11.5 Key Countries Analysis
  11.5.1 Germany
  11.5.2 France
  11.5.3 United Kingdom
  11.5.4 Italy
  11.5.5 Spain
  11.5.6 Belgium
  11.5.7 Netherlands
  11.5.8 Austria
  11.5.9 Poland
  11.5.10 Russia

CHAPTER 12 HISTORICAL AND FORECAST CYSTIC FIBROSIS THERAPEUTICS MARKET IN MEA (2020-2030)

12.1 Cystic Fibrosis Therapeutics Market Size
12.2 Cystic Fibrosis Therapeutics Market by End Use
12.3 Competition by Players/Suppliers
12.4 Cystic Fibrosis Therapeutics Market Size by Type
12.5 Key Countries Analysis
  12.5.1 Egypt
  12.5.2 Israel
  12.5.3 South Africa
  12.5.4 Gulf Cooperation Council Countries
  12.5.5 Turkey

CHAPTER 13 SUMMARY FOR GLOBAL CYSTIC FIBROSIS THERAPEUTICS MARKET (2020-2025)

13.1 Cystic Fibrosis Therapeutics Market Size
13.2 Cystic Fibrosis Therapeutics Market by End Use
13.3 Competition by Players/Suppliers
13.4 Cystic Fibrosis Therapeutics Market Size by Type

CHAPTER 14 GLOBAL CYSTIC FIBROSIS THERAPEUTICS MARKET FORECAST (2025-2030)

14.1 Cystic Fibrosis Therapeutics Market Size Forecast
14.2 Cystic Fibrosis Therapeutics Application Forecast
14.3 Competition by Players/Suppliers
14.4 Cystic Fibrosis Therapeutics Type Forecast

CHAPTER 15 ANALYSIS OF GLOBAL KEY VENDORS

15.1 Vertex Pharmaceuticals
  15.1.1 Company Profile
  15.1.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.1.3 SWOT Analysis of Vertex Pharmaceuticals
  15.1.4 Vertex Pharmaceuticals Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.2 AbbVie
  15.2.1 Company Profile
  15.2.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.2.3 SWOT Analysis of AbbVie
  15.2.4 AbbVie Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.3 Gilead
  15.3.1 Company Profile
  15.3.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.3.3 SWOT Analysis of Gilead
  15.3.4 Gilead Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.4 Roche
  15.4.1 Company Profile
  15.4.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.4.3 SWOT Analysis of Roche
  15.4.4 Roche Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.5 Alcresta Therapeutics
  15.5.1 Company Profile
  15.5.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.5.3 SWOT Analysis of Alcresta Therapeutics
  15.5.4 Alcresta Therapeutics Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.6 Chiesi Farmaceutici
  15.6.1 Company Profile
  15.6.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.6.3 SWOT Analysis of Chiesi Farmaceutici
  15.6.4 Chiesi Farmaceutici Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.7 Merck
  15.7.1 Company Profile
  15.7.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.7.3 SWOT Analysis of Merck
  15.7.4 Merck Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
15.8 AstraZeneca
  15.8.1 Company Profile
  15.8.2 Main Business and Cystic Fibrosis Therapeutics Information
  15.8.3 SWOT Analysis of AstraZeneca
  15.8.4 AstraZeneca Cystic Fibrosis Therapeutics Revenue, Gross Margin and Market Share (2020-2025)
Please ask for sample pages for full companies list
Tables and Figures
Table Abbreviation and Acronyms
Table Research Scope of Cystic Fibrosis Therapeutics Report
Table Data Sources of Cystic Fibrosis Therapeutics Report
Table Major Assumptions of Cystic Fibrosis Therapeutics Report
Figure Market Size Estimated Method
Figure Major Forecasting Factors
Figure Cystic Fibrosis Therapeutics Picture
Table Cystic Fibrosis Therapeutics Classification
Table Cystic Fibrosis Therapeutics Applications
Table Drivers of Cystic Fibrosis Therapeutics Market
Table Restraints of Cystic Fibrosis Therapeutics Market
Table Opportunities of Cystic Fibrosis Therapeutics Market
Table Threats of Cystic Fibrosis Therapeutics Market
Table Covid-19 Impact For Cystic Fibrosis Therapeutics Market
Table Raw Materials Suppliers
Table Different Production Methods of Cystic Fibrosis Therapeutics
Table Cost Structure Analysis of Cystic Fibrosis Therapeutics
Table Key End Users
Table Latest News of Cystic Fibrosis Therapeutics Market
Table Merger and Acquisition
Table Planned/Future Project of Cystic Fibrosis Therapeutics Market
Table Policy of Cystic Fibrosis Therapeutics Market
Table 2020-2030 North America Cystic Fibrosis Therapeutics Market Size
Figure 2020-2030 North America Cystic Fibrosis Therapeutics Market Size and CAGR
Table 2020-2030 North America Cystic Fibrosis Therapeutics Market Size by Application
Table 2020-2025 North America Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 North America Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 North America Cystic Fibrosis Therapeutics Market Size by Type
Table 2020-2030 United States Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Canada Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Mexico Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South America Cystic Fibrosis Therapeutics Market Size
Figure 2020-2030 South America Cystic Fibrosis Therapeutics Market Size and CAGR
Table 2020-2030 South America Cystic Fibrosis Therapeutics Market Size by Application
Table 2020-2025 South America Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 South America Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 South America Cystic Fibrosis Therapeutics Market Size by Type
Table 2020-2030 Brazil Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Argentina Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Chile Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Peru Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size
Figure 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size and CAGR
Table 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size by Application
Table 2020-2025 Asia & Pacific Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 Asia & Pacific Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size by Type
Table 2020-2030 China Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 India Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Japan Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South Korea Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Southeast Asia Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Australia Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size
Figure 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size and CAGR
Table 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size by Application
Table 2020-2025 Europe Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 Europe Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size by Type
Table 2020-2030 Germany Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 France Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 United Kingdom Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Italy Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Spain Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Belgium Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Netherlands Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Austria Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Poland Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Russia Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 MEA Cystic Fibrosis Therapeutics Market Size
Figure 2020-2030 MEA Cystic Fibrosis Therapeutics Market Size and CAGR
Table 2020-2030 MEA Cystic Fibrosis Therapeutics Market Size by Application
Table 2020-2025 MEA Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 MEA Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 MEA Cystic Fibrosis Therapeutics Market Size by Type
Table 2020-2030 Egypt Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Israel Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South Africa Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Gulf Cooperation Council Countries Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Turkey Cystic Fibrosis Therapeutics Market Size
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size by Region
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size Share by Region
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size by Application
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Share by Application
Table 2020-2025 Global Cystic Fibrosis Therapeutics Key Vendors Revenue
Figure 2020-2025 Global Cystic Fibrosis Therapeutics Market Size and Growth Rate
Table 2020-2025 Global Cystic Fibrosis Therapeutics Key Vendors Market Share
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size by Type
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Share by Type
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size by Region
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size Share by Region
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size by Application
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Share by Application
Table 2025-2030 Global Cystic Fibrosis Therapeutics Key Vendors Revenue
Figure 2025-2030 Global Cystic Fibrosis Therapeutics Market Size and Growth Rate
Table 2025-2030 Global Cystic Fibrosis Therapeutics Key Vendors Market Share
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size by Type
Table 2025-2030 Cystic Fibrosis Therapeutics Global Market Share by Type