Non-Alcoholic Fatty Liver Disease (NAFLD) Forecast in 11 Major Markets 2017-2027

April 2017 | 50 pages | ID: N399B71270DEN
Black Swan Analysis limited

Abstracts

Non-alcoholic fatty liver disease (NAFLD) is the presence of hepatic steatosis in the absence of competing liver disease. It is a spectrum of liver disorders associated with steatosis, with no evidence of significant alcohol consumption. NAFLD develops in four main stages; Steatosis (simple fatty liver), Non-alcoholic steatohepatitis (NASH), Fibrosis and Cirrhosis.

Non-alcoholic steatohepatitis (NASH) is a more serious form of steatosis, due to the added inflammation. It is defined as the presence of hepatic steatosis and inflammation with hepatocyte injury (ballooning) with or without fibrosis. This can progress to cirrhosis, liver failure and, more rarely, hepatocellular carcinoma.

This report provides the current prevalent population for Non-alcoholic fatty liver disease (NAFLD) across 11 Major Markets (USA, Canada, France, Germany, Italy, Spain, UK, Japan, Brazil, India and China) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.

Providing a value-added level of insight from the analysis team at Black Swan, several of the main symptoms and co-morbidities of NAFLD have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.

This report is built using data and information sourced from the proprietary Epiomic patient segmentation database. To generate accurate patient population estimates, the Epiomic database utilises a combination of several world class sources that deliver the most up to date information form patient registries, clinical trials and epidemiology studies. All of the sources used to generate the data and analysis have been identified in the report.

REASON TO BUY

• Able to quantify patient populations in global NAFLD market to target the development of future products, pricing strategies and launch plans.
• Gain further insight into the prevalence of the subdivided types of NAFLD, including NASH, and identify patient segments with high potential.
• Delivery of more accurate information for clinical trials in study sizing and realistic patient recruitment for various countries.
• Provide a level of understanding on the impact from specific co-morbid conditions on NAFLD prevalent population.
• Identify sub-populations within NAFLD which require treatment.
• Gain an understanding of the specific markets that have the largest number of NAFLD patients.

Contents

Introduction
NASH
Cause of the Disease
Risk Factors & Prevention
Diagnosis of the Disease
  Stages of Fibrosis
Variation by Geography/Ethnicity
Disease Prognosis & Clinical Course
Key Comorbid Conditions/Features Associated with the Disease
Methodology for quantification of patient numbers
Top-line Prevalence of NAFLD
Features of NAFLD patients
  Comorbid conditions in NAFLD patients
Prevalence of NASH
  Grades of Fibrosis in NASH patients
Abbreviations used in the report
Other Black Swan Analysis Publications
Black Swan Analysis Online Patient-Based Databases
Patient-Based Offering
Online Pricing Data and Platforms
References
Appendix

List Of Tables

LIST OF TABLES

NAFLD activity score (NAS)
Prevalence of NAFLD, total (000s)
Prevalence of NAFLD, males (000s)
Prevalence of NAFLD, females (000s)
NAFLD patients by stage, total (000s)
Body mass index (BMI) effect on NAFLD prevalence, total (000s)
NAFLD patients with diabetes, total (000s)
NAFLD patients with metabolic syndrome, total (000s)
NAFLD patients with hypertension, total (000s)
NAFLD patients with cerebrovascular disease, total (000s)
NAFLD patients with coronary artery disease, total (000s)
Prevalence of NASH, total (000s)
Prevalence of NASH, males (000s)
Prevalence of NASH, females (000s)
Grade of fibrosis in NASH patients, total (000s)
Abbreviations and Acronyms used in the report
USA Prevalence of NAFLD by 5-yr age cohort, males (000s)
USA Prevalence of NAFLD by 5-yr age cohort, females (000s)
Canada Prevalence of NAFLD by 5-yr age cohort, males (000s)
Canada Prevalence of NAFLD by 5-yr age cohort, females (000s)
France Prevalence of NAFLD by 5-yr age cohort, males (000s)
France Prevalence of NAFLD by 5-yr age cohort, females (000s)
Germany Prevalence of NAFLD by 5-yr age cohort, males (000s)
Germany Prevalence of NAFLD by 5-yr age cohort, females (000s)
Italy Prevalence of NAFLD by 5-yr age cohort, males (000s)
Italy Prevalence of NAFLD by 5-yr age cohort, females (000s)
Spain Prevalence of NAFLD by 5-yr age cohort, males (000s)
Spain Prevalence of NAFLD by 5-yr age cohort, females (000s)
UK Prevalence of NAFLD by 5-yr age cohort, males (000s)
UK Prevalence of NAFLD by 5-yr age cohort, females (000s)
Brazil Prevalence of NAFLD by 5-yr age cohort, males (000s)
Brazil Prevalence of NAFLD by 5-yr age cohort, females (000s)
Japan Prevalence of NAFLD by 5-yr age cohort, males (000s)
Japan Prevalence of NAFLD by 5-yr age cohort, females (000s)
India Prevalence of NAFLD by 5-yr age cohort, males (000s)
India Prevalence of NAFLD by 5-yr age cohort, females (000s)
China Prevalence of NAFLD by 5-yr age cohort, males (000s)
China Prevalence of NAFLD by 5-yr age cohort, females (000s)