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Drugs Toxicity Turned Into Burning Issue for Pharmaceutical Manufacturers, According to Kalorama Information

11 Oct 2012 • by Natalie Aster

The toxicity of drugs is an important concern for pharmaceutical manufacturers, as seen with fairly recent scares such as Vioxx, FenPhen and Baycol—products that seemed to be free of toxicity challenges during testing but caused damage to patients once launched. For many companies, this means considering these issues early, at the discovery stage, and often requires the assistance of an outsourcing company. There could be a $1.1 billion market by 2015 for companies that can help pharmaceutical companies with early toxicology services. This projection was made in its most recent report: “Early Toxicology: Markets and Approaches”.

Report Details:

Early Toxicology: Markets and Approaches
Published: September, 2012
Pages: 180
Price: US$ 3.995,00

“Toxicity properties are not the same as chemical discovery ones, they are biological and descriptive; they are not as easy to quantify,” said Melissa Elder, Kalorama Information analyst and author of the report. “It is common now to turn over this process to specialist companies.”

At first glance, the discovery of new drugs is a straightforward process of screening compound candidates, optimizing leads, performing pre-clinical evaluations and then, with these steps completed, clinical trials can begin. According to the report, the reality is not so neat. These activities often overlap, merge, and conflict with each other. Early toxicology testing is emerging as one of the most significant areas of drug discovery, and an integral part of all aspects of drug discovery and development.

“Early toxicology is done not only to discover problem compounds, but also to provide directions for compound development,” Elder said.

To assist in the process, service suppliers have expanded their range of offerings into the discovery area, now that pharmaceutical companies have become more willing to have early toxicology tests run by others. Kalorama details many of the companies offering early toxicology services in its report. CROs like Covance, Accelrys, Charles River, Albany Molecular, CeeTox and Quintiles are among those that offer either computer modeling, in vitro assays or animal testing services.

The Kalorama Information’s report contains segment market estimates for early toxicology, profiles of key companies and interviews with pharmaceutical experts.

More information can be found in the report “Early Toxicology: Markets and Approaches” by Kalorama Information.

To order the report or ask for sample pages contact [email protected]

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