Significant Drug Launches in 2019: A BCC Research Analysis and Insights on Pharmaceutical Industry
REPORT SCOPE:
The current report provides details about drug molecules that have been or will be launched in the market in 2019. This report highlights information and insights on the molecules. The report includes drug overviews, mechanisms of action, disease backgrounds, currently available treatments for diseases that these drugs address, clinical evidence on safety and efficacy, regulatory scenarios, market scope of the drugs and company profiles of manufactures.
REPORT INCLUDES:
The current report provides details about drug molecules that have been or will be launched in the market in 2019. This report highlights information and insights on the molecules. The report includes drug overviews, mechanisms of action, disease backgrounds, currently available treatments for diseases that these drugs address, clinical evidence on safety and efficacy, regulatory scenarios, market scope of the drugs and company profiles of manufactures.
REPORT INCLUDES:
- Information on the top potential drug launches by pharma companies in 2019
- Knowledge about drug, mechanism of action, and briefing of clinical evidences
- Detailed information and insights on the drug Upadacitinib which is manufactured by AbbVie Inc. , Ultomiris (ravulizumab-cwvz) a humanized monoclonal antibody manufactured by Alexion Pharmaceuticals Inc. and many more
- Insights into regulatory approvals, market scope, and analysis of pipeline molecules
- Detailed profiles of the companies and competitors related to the industry
CHAPTER 1 INTRODUCTION
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
CHAPTER 2 SIGNIFICANT DRUG LAUNCHES
CHAPTER 3 ULTOMIRIS (RAVULIZUMAB)
Overview of Ultomiris
Scientific Summary
Pharmacodynamics and Mechanism of Action
Pharmacokinetics
Therapeutic Trials of Ultomiris on Safety and Efficacy
Adverse Drug Reactions
Disease Background
Epidemiology of PNH
Pathophysiology
Symptoms of PNH
Currently Available Treatment for PNH
Pipeline Molecules for PNH
Regulatory and Development Milestones of Ultomiris
Market Scope for Ultomiris
Current PNH Market
Ultomiris Market
Market Drivers
Pharmaceutical Pricing and Reimbursement
Ultomiris Exclusivity
Company Profile
ALEXION PHARMACEUTICALS INC.
CHAPTER 4 RINVOQ (UPADACITINIB)
Drug Overview
Scientific Summary
Pharmacodynamics and Mechanism of Action
Pharmacokinetics
Therapeutic Trials of Upadacitinib on Safety and Efficacy
Adverse Drug Reactions
Disease Background
Epidemiology
Pathophysiology of RA
Etiology
Symptoms of RA
Unmet Needs
Current Available Treatment for RA
Pipeline Molecules
Regulatory Status of Upadacitinib
Market Scope for Upadacitinib
Current RA Market
Market Drivers
Upadacitinib Market
Company Profile
ABBVIE INC.
CHAPTER 5 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Disease Background
Classification of SMA
Epidemiology
Pathophysiology
SMA Therapeutics Pipeline
Currently Available Treatment for SMA
Market Scope for Drug XX
Current SMA Market
Drivers for SMA Market
Drug XX Market
Company Profile
NOVARTIS AG
CHAPTER 6 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials of Brolucizumab on Safety and Efficacy
Disease Background
Epidemiology
Disease Subtypes
Classification of AMD
Etiology
Pathophysiology
Unmet Needs of AMD
Currently Available Treatment for AMD
Laser Photocoagulation
Photodynamic Therapy
Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Drugs
Pipeline Molecules for AMD
Status of Regulatory Approval of Drug XX
Market Scope for Drug XX
Current Market Size of AMD
Market Drivers
Impact of Drug XX on AMD Market
Company Profile
CHAPTER 7 DRUG XX
Drug Overview
Scientific Summary
Pharmacokinetics
Mechanism of Action
Adverse Events
Therapeutic Trials on Safety and Efficacy of Mayzent
Disease Background
Epidemiology
Pathophysiology
Types of MS
Symptoms of MS
Unmet Needs of MS
Regulatory Approval of Drug XX
Current Available Treatment for MS
Pipeline Molecules for MS
Market Scope for Drug XX
Current Multiple Sclerosis Market
Impact of Drug XX on MS Market
Company Profiles
CHAPTER 8 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Pharmacokinetics
Therapeutic Trials on Efficacy and Safety of Risankizumab
Disease Background
Epidemiology
Pathophysiology
Types of Psoriasis
Regulatory and Development Milestones
Currently Available Treatment for Psoriasis
Biologics
Systemics
Phototherapy
Pipeline Molecules
Market Scope for Drug XX
Current Psoriasis Market
Drug XX Market
Company Profiles
CHAPTER 9 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Safety and Efficacy of LentiGlobin
Disease Background
Epidemiology
Types of Thalassemia
Pathophysiology
Regulatory and Development Milestones
Currently Available Treatment
Chelating Therapy
Pipeline Molecules
Market Scope for Drug XX
Current Beta Thalassemia Market
Drug XX Market
Company Profile
BLUEBIRD BIO INC.
CHAPTER 10 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Safety and Efficacy of Ozanimod
Disease Background
Epidemiology
Pathophysiology
Types of MS
Symptoms of MS
Unmet Needs of MS
Currently Available Treatment for MS
Pipeline Molecules of MS
Regulatory and Developmental Milestones
Market Scope for Drug XX
Company Profile
CELGENE CORP.
CHAPTER 11 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Safety and Efficacy of AR101
Disease Background
Types of Allergic Reactions
Focus on Peanut Allergy
Management of Peanut Allergy
Regulatory and Development Milestones
Market Scope for Drug XX
Company Profile
AIMMUNE THERAPEUTICS INC.
CHAPTER 12 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Efficacy and Safety of Filgotinib
Disease Background
Epidemiology
Pathophysiology of RA
Etiology
Symptoms of RA
Unmet Needs
Currently Available Treatment for Rheumatoid Arthritis
Pipeline Molecules
Market Scope for Drug XX
Current RA Market
Drug XX Market
Company Profile
GILEAD SCIENCES INC.
CHAPTER 13 CONCLUSION
CHAPTER 14 APPENDIX: ACRONYMS
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
CHAPTER 2 SIGNIFICANT DRUG LAUNCHES
CHAPTER 3 ULTOMIRIS (RAVULIZUMAB)
Overview of Ultomiris
Scientific Summary
Pharmacodynamics and Mechanism of Action
Pharmacokinetics
Therapeutic Trials of Ultomiris on Safety and Efficacy
Adverse Drug Reactions
Disease Background
Epidemiology of PNH
Pathophysiology
Symptoms of PNH
Currently Available Treatment for PNH
Pipeline Molecules for PNH
Regulatory and Development Milestones of Ultomiris
Market Scope for Ultomiris
Current PNH Market
Ultomiris Market
Market Drivers
Pharmaceutical Pricing and Reimbursement
Ultomiris Exclusivity
Company Profile
ALEXION PHARMACEUTICALS INC.
CHAPTER 4 RINVOQ (UPADACITINIB)
Drug Overview
Scientific Summary
Pharmacodynamics and Mechanism of Action
Pharmacokinetics
Therapeutic Trials of Upadacitinib on Safety and Efficacy
Adverse Drug Reactions
Disease Background
Epidemiology
Pathophysiology of RA
Etiology
Symptoms of RA
Unmet Needs
Current Available Treatment for RA
Pipeline Molecules
Regulatory Status of Upadacitinib
Market Scope for Upadacitinib
Current RA Market
Market Drivers
Upadacitinib Market
Company Profile
ABBVIE INC.
CHAPTER 5 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Disease Background
Classification of SMA
Epidemiology
Pathophysiology
SMA Therapeutics Pipeline
Currently Available Treatment for SMA
Market Scope for Drug XX
Current SMA Market
Drivers for SMA Market
Drug XX Market
Company Profile
NOVARTIS AG
CHAPTER 6 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials of Brolucizumab on Safety and Efficacy
Disease Background
Epidemiology
Disease Subtypes
Classification of AMD
Etiology
Pathophysiology
Unmet Needs of AMD
Currently Available Treatment for AMD
Laser Photocoagulation
Photodynamic Therapy
Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Drugs
Pipeline Molecules for AMD
Status of Regulatory Approval of Drug XX
Market Scope for Drug XX
Current Market Size of AMD
Market Drivers
Impact of Drug XX on AMD Market
Company Profile
CHAPTER 7 DRUG XX
Drug Overview
Scientific Summary
Pharmacokinetics
Mechanism of Action
Adverse Events
Therapeutic Trials on Safety and Efficacy of Mayzent
Disease Background
Epidemiology
Pathophysiology
Types of MS
Symptoms of MS
Unmet Needs of MS
Regulatory Approval of Drug XX
Current Available Treatment for MS
Pipeline Molecules for MS
Market Scope for Drug XX
Current Multiple Sclerosis Market
Impact of Drug XX on MS Market
Company Profiles
CHAPTER 8 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Pharmacokinetics
Therapeutic Trials on Efficacy and Safety of Risankizumab
Disease Background
Epidemiology
Pathophysiology
Types of Psoriasis
Regulatory and Development Milestones
Currently Available Treatment for Psoriasis
Biologics
Systemics
Phototherapy
Pipeline Molecules
Market Scope for Drug XX
Current Psoriasis Market
Drug XX Market
Company Profiles
CHAPTER 9 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Safety and Efficacy of LentiGlobin
Disease Background
Epidemiology
Types of Thalassemia
Pathophysiology
Regulatory and Development Milestones
Currently Available Treatment
Chelating Therapy
Pipeline Molecules
Market Scope for Drug XX
Current Beta Thalassemia Market
Drug XX Market
Company Profile
BLUEBIRD BIO INC.
CHAPTER 10 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Safety and Efficacy of Ozanimod
Disease Background
Epidemiology
Pathophysiology
Types of MS
Symptoms of MS
Unmet Needs of MS
Currently Available Treatment for MS
Pipeline Molecules of MS
Regulatory and Developmental Milestones
Market Scope for Drug XX
Company Profile
CELGENE CORP.
CHAPTER 11 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Safety and Efficacy of AR101
Disease Background
Types of Allergic Reactions
Focus on Peanut Allergy
Management of Peanut Allergy
Regulatory and Development Milestones
Market Scope for Drug XX
Company Profile
AIMMUNE THERAPEUTICS INC.
CHAPTER 12 DRUG XX
Drug Overview
Scientific Summary
Mechanism of Action
Therapeutic Trials on Efficacy and Safety of Filgotinib
Disease Background
Epidemiology
Pathophysiology of RA
Etiology
Symptoms of RA
Unmet Needs
Currently Available Treatment for Rheumatoid Arthritis
Pipeline Molecules
Market Scope for Drug XX
Current RA Market
Drug XX Market
Company Profile
GILEAD SCIENCES INC.
CHAPTER 13 CONCLUSION
CHAPTER 14 APPENDIX: ACRONYMS
LIST OF TABLES
Table 1: Potential Launches to Watch, 2019
Table 2: Top Companies Investing in R&D, 2018
Table 3: Potential Drug Launches, 2018
Table 4: Key Clinical Trials of Ultomiris
Table 5: Common Symptoms of PNH
Table 6: Other Pipeline Drugs for PNH
Table 7: Key Development Milestones of Ultomiris
Table 8: Alexion Pharmaceuticals Inc.: Financial Performance, 2016-2018
Table 9: Alexion Pharmaceuticals Inc.: Product Portfolio
Table 10: Alexion Pharmaceuticals Inc.: Pipeline Molecules
Table 11: Alexion Pharmaceuticals, Inc.: Recent Acquisitions
Table 12: Clinical Evidence of Safety and Efficacy of Upadacitinib
Table 13: Epidemiological Forecast for Diagnosed Prevalent Cases of Rheumatoid Arthritis, by Region, Through 2022
Table 14: Common Symptoms of RA
Table 15: Unmet Needs of RA
Table 16: Current Treatment for RA
Table 17: Pipeline Molecules for RA
Table 18: Others Pipeline Drug for JAK Inhibitors
Table 19: AbbVie, Inc.: Financial Performance, 2016-2018
Table 20: AbbVie Inc.: Product Portfolio
Table 21: AbbVie Inc.: Pipeline Molecules
Table 22: AbbVie Inc.: Recent Acquisitions
Table 23: Classification of SMA
Table 24: Milestones in Discovery of SMA
Table 25: Pipeline Molecules, SMA
Table 26: Novartis AG: Financial Performance, 2016-2018
Table 27: Novartis AG: Product Portfolio, Oncology
Table 28: Novartis AG: Product Portfolio, Ophthalmology
Table 29: Novartis AG: Product Portfolio, Immunology Hepatology and Dermatology
Table 30: Novartis AG: Product Portfolio, Neuroscience
Table 31: Novartis AG: Product Portfolio, Respiratory
Table 32: Novartis AG: Product Portfolio, Pipeline Molecules
Table 33: Novartis AG: Recent Acquisitions
Table 34: Therapeutic Trials of Brolucizumab on Safety and Efficacy
Table 35: Projected Number of People with AMD, by Region, Through 2024
Table 36: AREDS Classification of AMD
Table 37: Pipeline Molecules for AMD
Table 38: Market Size of Lucentis and Eylea, Through 2022
Table 39: Incident and Prevalent Cases of MS, by Country, 2016
Table 40: Incident and Prevalent Cases of MS, by Region, 2016
Table 41: Currently Approved Disease Modifying Therapies for MS, Injectable Treatments
Table 42: Currently Approved Disease Modifying Therapies for MS, Oral Treatments
Table 43: Currently Approved Disease Modifying Therapies for MS, Intravenous Infusion Treatments
Table 44: Pipeline Molecules for Multiple Sclerosis Showing Promising Results
Table 45: Development Milestones of Risankizumab
Table 46: Currently Available Treatment for Psoriasis, Biologics
Table 47: Pipeline Molecules in Development for Psoriasis and Related Conditions: Phase III
Table 48: Pipeline Molecules in Development for Psoriasis and Related Conditions: Phase II
Table 49: Global Psoriasis Market, by Region/Country, Through 2022
Table 50: Pipeline Molecules: Beta Thalassemia
Table 51: Bluebird Bio Inc.: Financial Performance, 2016-2018
Table 52: Bluebird Bio Inc.: Pipeline Molecules as of 2019
Table 53: Currently Approved Disease Modifying Therapies for MS, Injectable Treatments
Table 54: Currently Approved Disease Modifying Therapies for MS, Oral Treatments
Table 55: Currently Approved Disease Modifying Therapies for MS, Intravenous Infusion Treatments
Table 56: Pipeline Molecules of Multiple Sclerosis Showing Promising Results
Table 57: Development Milestones of Ozanimod as of 2019
Table 58: Celgene Corp.: Revenue Details, 2016-2018
Table 59: Celgene Corp.: Marketed Products
Table 60: Celgene Corp.: Company Agreements
Table 61: Common Symptoms of Peanut Allergy
Table 62: Common Symptoms of Rheumatoid Arthritis
Table 63: Unmet Needs of Rheumatoid Arthritis
Table 64: Current Treatment for Rheumatoid Arthritis
Table 65: Pipeline Molecules for Rheumatoid Arthritis
Table 66: Gilead Sciences Inc.: Net Revenue, 2016-2018
Table 67: Gilead Science Inc.: Marketed Products
Table 68: Gilead Science Inc.: Pipeline Molecules
Table 69: Acronyms Used in This Report
Table 1: Potential Launches to Watch, 2019
Table 2: Top Companies Investing in R&D, 2018
Table 3: Potential Drug Launches, 2018
Table 4: Key Clinical Trials of Ultomiris
Table 5: Common Symptoms of PNH
Table 6: Other Pipeline Drugs for PNH
Table 7: Key Development Milestones of Ultomiris
Table 8: Alexion Pharmaceuticals Inc.: Financial Performance, 2016-2018
Table 9: Alexion Pharmaceuticals Inc.: Product Portfolio
Table 10: Alexion Pharmaceuticals Inc.: Pipeline Molecules
Table 11: Alexion Pharmaceuticals, Inc.: Recent Acquisitions
Table 12: Clinical Evidence of Safety and Efficacy of Upadacitinib
Table 13: Epidemiological Forecast for Diagnosed Prevalent Cases of Rheumatoid Arthritis, by Region, Through 2022
Table 14: Common Symptoms of RA
Table 15: Unmet Needs of RA
Table 16: Current Treatment for RA
Table 17: Pipeline Molecules for RA
Table 18: Others Pipeline Drug for JAK Inhibitors
Table 19: AbbVie, Inc.: Financial Performance, 2016-2018
Table 20: AbbVie Inc.: Product Portfolio
Table 21: AbbVie Inc.: Pipeline Molecules
Table 22: AbbVie Inc.: Recent Acquisitions
Table 23: Classification of SMA
Table 24: Milestones in Discovery of SMA
Table 25: Pipeline Molecules, SMA
Table 26: Novartis AG: Financial Performance, 2016-2018
Table 27: Novartis AG: Product Portfolio, Oncology
Table 28: Novartis AG: Product Portfolio, Ophthalmology
Table 29: Novartis AG: Product Portfolio, Immunology Hepatology and Dermatology
Table 30: Novartis AG: Product Portfolio, Neuroscience
Table 31: Novartis AG: Product Portfolio, Respiratory
Table 32: Novartis AG: Product Portfolio, Pipeline Molecules
Table 33: Novartis AG: Recent Acquisitions
Table 34: Therapeutic Trials of Brolucizumab on Safety and Efficacy
Table 35: Projected Number of People with AMD, by Region, Through 2024
Table 36: AREDS Classification of AMD
Table 37: Pipeline Molecules for AMD
Table 38: Market Size of Lucentis and Eylea, Through 2022
Table 39: Incident and Prevalent Cases of MS, by Country, 2016
Table 40: Incident and Prevalent Cases of MS, by Region, 2016
Table 41: Currently Approved Disease Modifying Therapies for MS, Injectable Treatments
Table 42: Currently Approved Disease Modifying Therapies for MS, Oral Treatments
Table 43: Currently Approved Disease Modifying Therapies for MS, Intravenous Infusion Treatments
Table 44: Pipeline Molecules for Multiple Sclerosis Showing Promising Results
Table 45: Development Milestones of Risankizumab
Table 46: Currently Available Treatment for Psoriasis, Biologics
Table 47: Pipeline Molecules in Development for Psoriasis and Related Conditions: Phase III
Table 48: Pipeline Molecules in Development for Psoriasis and Related Conditions: Phase II
Table 49: Global Psoriasis Market, by Region/Country, Through 2022
Table 50: Pipeline Molecules: Beta Thalassemia
Table 51: Bluebird Bio Inc.: Financial Performance, 2016-2018
Table 52: Bluebird Bio Inc.: Pipeline Molecules as of 2019
Table 53: Currently Approved Disease Modifying Therapies for MS, Injectable Treatments
Table 54: Currently Approved Disease Modifying Therapies for MS, Oral Treatments
Table 55: Currently Approved Disease Modifying Therapies for MS, Intravenous Infusion Treatments
Table 56: Pipeline Molecules of Multiple Sclerosis Showing Promising Results
Table 57: Development Milestones of Ozanimod as of 2019
Table 58: Celgene Corp.: Revenue Details, 2016-2018
Table 59: Celgene Corp.: Marketed Products
Table 60: Celgene Corp.: Company Agreements
Table 61: Common Symptoms of Peanut Allergy
Table 62: Common Symptoms of Rheumatoid Arthritis
Table 63: Unmet Needs of Rheumatoid Arthritis
Table 64: Current Treatment for Rheumatoid Arthritis
Table 65: Pipeline Molecules for Rheumatoid Arthritis
Table 66: Gilead Sciences Inc.: Net Revenue, 2016-2018
Table 67: Gilead Science Inc.: Marketed Products
Table 68: Gilead Science Inc.: Pipeline Molecules
Table 69: Acronyms Used in This Report
LIST OF FIGURES
Figure 1: Percentage Distribution of R&D Spending for Clinical Development of Novel Drugs, by Therapeutic Category, 2019
Figure 2: Market Share Analysis of Major Players in the Global Pharmaceutical Industry, 2018
Figure 3: Soliris: Net Product Revenues, 2014-2018
Figure 4: Spinraza: Market Size, 2016-2018
Figure 5: Novartis AG: Spending on Research and Development, by Division, 2017 and 2018
Figure 6: Brolucizumab: Mechanism of Action
Figure 7: Top Eight Food Items Triggering Allergy and Number of Children Affected, 2018
Figure 8: Percentage Distribution of Drug Launches, by Therapeutic Category, 2019
Figure 1: Percentage Distribution of R&D Spending for Clinical Development of Novel Drugs, by Therapeutic Category, 2019
Figure 2: Market Share Analysis of Major Players in the Global Pharmaceutical Industry, 2018
Figure 3: Soliris: Net Product Revenues, 2014-2018
Figure 4: Spinraza: Market Size, 2016-2018
Figure 5: Novartis AG: Spending on Research and Development, by Division, 2017 and 2018
Figure 6: Brolucizumab: Mechanism of Action
Figure 7: Top Eight Food Items Triggering Allergy and Number of Children Affected, 2018
Figure 8: Percentage Distribution of Drug Launches, by Therapeutic Category, 2019
