Pneumococcal Disease - Pipeline Insight, 2021
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DelveInsight’s, “Pneumococcal Disease – Pipeline Insight, 2021,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in the Pneumococcal Disease pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Pneumococcal Disease: Overview
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae or pneumococcus. Disease is most common at the extremes of age, i.e, in young children and among the elderly. There are two main types of pneumococcal disease: non invasive and invasive with noninvasive being the less serious. Non Invasive Pneumococcal disease: it occurs outside the major organs of the blood and the bacteria can cause- Bronchitis, Sinusitis. Invasive pneumococcal diseases: Invasive pneumococcal diseases (IPDs) are more serious than the noninvasive type and occur inside a major organ or in a person’s blood and the bacteria can cause: Pneumonia, Meningitis and sepsis. S. pneumoniae bacteria are common in the throat and nose. Bacteria can spread through droplets in the air and do not spread through contaminated food or water.
“Pneumococcal Disease - Pipeline Insight, 2021” report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pneumococcal Disease pipeline landscape is provided which includes the disease overview and Pneumococcal Disease treatment guidelines. The assessment part of the report embraces, in depth Pneumococcal Disease commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pneumococcal Disease collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Pneumococcal Disease R&D. The therapies under development are focused on novel approaches to treat/improve Pneumococcal Disease.
Pneumococcal Disease Emerging Drugs Chapters
This segment of the Pneumococcal Disease report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Pneumococcal Disease Emerging Drugs
20 Valent Pneumococcal conjugate vaccine (20vPnC): Pfizer
Pfizer’s 20vPnC vaccine candidate includes capsular polysaccharide conjugates for the 13 serotypes already included in Prevnar 13® (Pneumococcal 13-valent Conjugate Vaccine[Diphtheria CRM197 Protein]). The vaccine also contains capsular polysaccharide conjugates for seven additional serotypes that cause invasive pneumococcal disease. U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for 20vPnC for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae serotypes in the vaccine candidate in adults age 18 years or older. If approved, 20vPnC will cover more serotypes responsible for the majority of pneumococcal disease than any other pneumococcal conjugate vaccine currently licensed or currently in late-stage clinical development. Importantly, 20vPnC has shown to induce immune memory, which provides protection and efficacy against non-bacteremic pneumonia, particularly in older adults.
ASP3772: Affinivax
ASP3772 utilizes the Multiple Antigen Presenting System (MAPS) platform which is Affinivax’s proprietary, next-generation vaccine technology. MAPS vaccine can present both the polysaccharide and the protein antigens to the host immune system to induce both a B- and T-cell immune response. ASP3772 is a vaccine candidate that offers the potential to provide broader protection against pneumococcal disease. It is currently in phase II stage of development by Affinivax partnership with Astellas Pharma Inc., includes 24 pneumococcal serotypes.
Further product details are provided in the report……..
Pneumococcal Disease: Therapeutic Assessment
This segment of the report provides insights about the different Pneumococcal Disease drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Pneumococcal Disease
There are approx. 5+ key companies which are developing the therapies for Pneumococcal Disease. The companies which have their Pneumococcal Disease drug candidates in the most advanced stage, i.e. pre-registration include, Pfizer.
Phases
DelveInsight’s report covers around 5+ products under different phases of clinical development like
The Pneumococcal Disease pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Pneumococcal Disease: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pneumococcal Disease therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pneumococcal Disease drugs.
Pneumococcal Disease Report Insights
Current Treatment Scenario and Emerging Therapies:
DelveInsight’s, “Pneumococcal Disease – Pipeline Insight, 2021,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in the Pneumococcal Disease pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Pneumococcal Disease: Overview
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae or pneumococcus. Disease is most common at the extremes of age, i.e, in young children and among the elderly. There are two main types of pneumococcal disease: non invasive and invasive with noninvasive being the less serious. Non Invasive Pneumococcal disease: it occurs outside the major organs of the blood and the bacteria can cause- Bronchitis, Sinusitis. Invasive pneumococcal diseases: Invasive pneumococcal diseases (IPDs) are more serious than the noninvasive type and occur inside a major organ or in a person’s blood and the bacteria can cause: Pneumonia, Meningitis and sepsis. S. pneumoniae bacteria are common in the throat and nose. Bacteria can spread through droplets in the air and do not spread through contaminated food or water.
“Pneumococcal Disease - Pipeline Insight, 2021” report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pneumococcal Disease pipeline landscape is provided which includes the disease overview and Pneumococcal Disease treatment guidelines. The assessment part of the report embraces, in depth Pneumococcal Disease commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pneumococcal Disease collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Pneumococcal Disease R&D. The therapies under development are focused on novel approaches to treat/improve Pneumococcal Disease.
Pneumococcal Disease Emerging Drugs Chapters
This segment of the Pneumococcal Disease report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Pneumococcal Disease Emerging Drugs
20 Valent Pneumococcal conjugate vaccine (20vPnC): Pfizer
Pfizer’s 20vPnC vaccine candidate includes capsular polysaccharide conjugates for the 13 serotypes already included in Prevnar 13® (Pneumococcal 13-valent Conjugate Vaccine[Diphtheria CRM197 Protein]). The vaccine also contains capsular polysaccharide conjugates for seven additional serotypes that cause invasive pneumococcal disease. U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for 20vPnC for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae serotypes in the vaccine candidate in adults age 18 years or older. If approved, 20vPnC will cover more serotypes responsible for the majority of pneumococcal disease than any other pneumococcal conjugate vaccine currently licensed or currently in late-stage clinical development. Importantly, 20vPnC has shown to induce immune memory, which provides protection and efficacy against non-bacteremic pneumonia, particularly in older adults.
ASP3772: Affinivax
ASP3772 utilizes the Multiple Antigen Presenting System (MAPS) platform which is Affinivax’s proprietary, next-generation vaccine technology. MAPS vaccine can present both the polysaccharide and the protein antigens to the host immune system to induce both a B- and T-cell immune response. ASP3772 is a vaccine candidate that offers the potential to provide broader protection against pneumococcal disease. It is currently in phase II stage of development by Affinivax partnership with Astellas Pharma Inc., includes 24 pneumococcal serotypes.
Further product details are provided in the report……..
Pneumococcal Disease: Therapeutic Assessment
This segment of the report provides insights about the different Pneumococcal Disease drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Pneumococcal Disease
There are approx. 5+ key companies which are developing the therapies for Pneumococcal Disease. The companies which have their Pneumococcal Disease drug candidates in the most advanced stage, i.e. pre-registration include, Pfizer.
Phases
DelveInsight’s report covers around 5+ products under different phases of clinical development like
- Late stage products (Phase III)
- Mid-stage products (Phase II and Phase I/II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
The Pneumococcal Disease pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Intravenous
- Subcutaneous
- Topical.
- Molecule Type
- Peptides
- Vaccines
- Gene therapy
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Pneumococcal Disease: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pneumococcal Disease therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pneumococcal Disease drugs.
Pneumococcal Disease Report Insights
- Pneumococcal Disease Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Pneumococcal Disease drugs?
- How many Pneumococcal Disease drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Pneumococcal Disease?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Pneumococcal Disease therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Pneumococcal Disease and their status?
- What are the key designations that have been granted to the emerging drugs?
- Pfizer
- Affinivax
- Merck Sharp &Dohme Corp.
- Vaxcyte
- SK Chemicals
- 20vPnC
- V114
- ASP3772
- VAX-A1
- Pneumococcal vaccine conjugate
Introduction
Executive Summary
Pneumococcal Disease: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Pneumococcal Disease – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Pneumococcal Disease companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Pneumococcal Disease Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Pre-registration)
Comparative Analysis
20vPnC: Pfizer
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
ASP3772: Affinivax
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
Drug Name: Company Name
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Pneumococcal Disease Key Companies
Pneumococcal Disease Key Products
Pneumococcal Disease- Unmet Needs
Pneumococcal Disease- Market Drivers and Barriers
Pneumococcal Disease- Future Perspectives and Conclusion
Pneumococcal Disease Analyst Views
Pneumococcal Disease Key Companies
Appendix
Executive Summary
Pneumococcal Disease: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Pneumococcal Disease – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Pneumococcal Disease companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Pneumococcal Disease Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Pre-registration)
Comparative Analysis
20vPnC: Pfizer
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
ASP3772: Affinivax
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
Drug Name: Company Name
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Pneumococcal Disease Key Companies
Pneumococcal Disease Key Products
Pneumococcal Disease- Unmet Needs
Pneumococcal Disease- Market Drivers and Barriers
Pneumococcal Disease- Future Perspectives and Conclusion
Pneumococcal Disease Analyst Views
Pneumococcal Disease Key Companies
Appendix
LIST OF TABLES
Table 1 Total Products for Pneumococcal Disease
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Table 1 Total Products for Pneumococcal Disease
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
LIST OF FIGURES
Figure 1 Total Products for Pneumococcal Disease
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Figure 1 Total Products for Pneumococcal Disease
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
