Metastatic Bone Pain- Pipeline insight, 2021
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DelveInsight’s, “Metastatic Bone pain – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Metastatic Bone pain pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Metastatic Bone pain: Overview
Bone metastasis occurs when cancer cells spread from their original site to a bone. The most common signs of bone metastases are pain, fracture (broken bone), spinal cord compression, and a high calcium blood level. Bone pain is usually the first symptom of bone metastases. Bone metastases can weaken bones and even result in fractures (breaks). Some bone metastases can cause calcium to leak from the bones into the bloodstream. This can lead to high calcium levels (hypercalcemia) in the blood. Bone metastases can be a part of advanced cancer. They are most common in breast and prostate cancer. Imaging studies such as a bone scan, x-rays, CT scan, PET, or MRI, may be used to diagnose bone metastases, depending on the particular situation.
“Metastatic Bone pain - Pipeline Insight, 2021” report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Metastatic Bone pain pipeline landscape is provided which includes the disease overview and Metastatic Bone pain treatment guidelines. The assessment part of the report embraces, in depth Metastatic Bone pain commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Metastatic Bone pain collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Metastatic Bone pain R&D. The therapies under development are focused on novel approaches to treat/improve Metastatic Bone pain.
Metastatic Bone pain Emerging Drugs Chapters
This segment of the Metastatic Bone pain report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Metastatic Bone pain Emerging Drugs
QL1206: Qilu Pharmaceutical Co., Ltd.
Denosumab is a humanized monoclonal antibody that is an inhibitor of the receptor activator of nuclear factor kappa-B ligand (RANKL), which works by preventing the development of osteoclasts which are cells that break down bone. It is used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone and giant cell tumour of bone. The Drug is currently in phase III stage of development for Bone metastases.
AL2846: Chia Tai Tianqing Pharmaceutical Group Co., Ltd
AL2846 is a multi-target tyrosine kinase receptor inhibitor with obvious selective to c-met, suggesting that its anti-tumor effect mainly inhibits the activation of key downstream oncogenic pathways by inhibiting expression of c-met, tumor angiogenesis and tumor cell migration. It is currently in phase II stage of development for bone metastatic non-small cell lung cancer.
Further product details are provided in the report……..
Metastatic Bone pain: Therapeutic Assessment
This segment of the report provides insights about the different Metastatic Bone pain drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Metastatic Bone pain
There are approx. 10+ key companies which are developing the therapies for Metastatic Bone pain. The companies which have their Metastatic Bone pain drug candidates in the most advanced stage, i.e. phase III include, Qilu Pharmaceuticals Co., Ltd.
Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
Metastatic Bone pain pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Metastatic Bone pain: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Metastatic Bone pain therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Metastatic Bone pain drugs.
Metastatic Bone pain Report Insights
Current Treatment Scenario and Emerging Therapies:
DelveInsight’s, “Metastatic Bone pain – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Metastatic Bone pain pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Metastatic Bone pain: Overview
Bone metastasis occurs when cancer cells spread from their original site to a bone. The most common signs of bone metastases are pain, fracture (broken bone), spinal cord compression, and a high calcium blood level. Bone pain is usually the first symptom of bone metastases. Bone metastases can weaken bones and even result in fractures (breaks). Some bone metastases can cause calcium to leak from the bones into the bloodstream. This can lead to high calcium levels (hypercalcemia) in the blood. Bone metastases can be a part of advanced cancer. They are most common in breast and prostate cancer. Imaging studies such as a bone scan, x-rays, CT scan, PET, or MRI, may be used to diagnose bone metastases, depending on the particular situation.
“Metastatic Bone pain - Pipeline Insight, 2021” report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Metastatic Bone pain pipeline landscape is provided which includes the disease overview and Metastatic Bone pain treatment guidelines. The assessment part of the report embraces, in depth Metastatic Bone pain commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Metastatic Bone pain collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Metastatic Bone pain R&D. The therapies under development are focused on novel approaches to treat/improve Metastatic Bone pain.
Metastatic Bone pain Emerging Drugs Chapters
This segment of the Metastatic Bone pain report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Metastatic Bone pain Emerging Drugs
QL1206: Qilu Pharmaceutical Co., Ltd.
Denosumab is a humanized monoclonal antibody that is an inhibitor of the receptor activator of nuclear factor kappa-B ligand (RANKL), which works by preventing the development of osteoclasts which are cells that break down bone. It is used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone and giant cell tumour of bone. The Drug is currently in phase III stage of development for Bone metastases.
AL2846: Chia Tai Tianqing Pharmaceutical Group Co., Ltd
AL2846 is a multi-target tyrosine kinase receptor inhibitor with obvious selective to c-met, suggesting that its anti-tumor effect mainly inhibits the activation of key downstream oncogenic pathways by inhibiting expression of c-met, tumor angiogenesis and tumor cell migration. It is currently in phase II stage of development for bone metastatic non-small cell lung cancer.
Further product details are provided in the report……..
Metastatic Bone pain: Therapeutic Assessment
This segment of the report provides insights about the different Metastatic Bone pain drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Metastatic Bone pain
There are approx. 10+ key companies which are developing the therapies for Metastatic Bone pain. The companies which have their Metastatic Bone pain drug candidates in the most advanced stage, i.e. phase III include, Qilu Pharmaceuticals Co., Ltd.
Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
Metastatic Bone pain pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Oral
- Intravenous
- Intramuscular
- Subcutaneous
- Molecule Type
- Peptides
- Polymer
- Small molecule
- Monoclonal antibody
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Metastatic Bone pain: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Metastatic Bone pain therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Metastatic Bone pain drugs.
Metastatic Bone pain Report Insights
- Metastatic Bone pain Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Metastatic Bone pain drugs?
- How many Metastatic Bone pain drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Metastatic Bone pain?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Metastatic Bone pain therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Metastatic Bone pain and their status?
- What are the key designations that have been granted to the emerging drugs?
- Qilu Pharmaceuticals Co., Ltd.
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Progenics Pharmaceuticals
- Yong Shun Technology Development
- Q.Biomed Inc.
- Shanghai JMT-Bio Inc
- JMT-100
- Anti-RANKL antibodies
- AL2846
- QL1206
- HS-20090
Introduction
Executive Summary
Metastatic Bone pain: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Metastatic Bone pain – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Metastatic Bone pain companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Metastatic Bone pain Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
QL1206: Qilu Pharmaceutical Co., Ltd.
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
AL2846: Chia Tai Tianqing Pharmaceutical Group Co., Ltd
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
JMT100: Yong Shun Technology Development
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Metastatic Bone pain Key Companies
Metastatic Bone pain Key Products
Metastatic Bone pain- Unmet Needs
Metastatic Bone pain- Market Drivers and Barriers
Metastatic Bone pain- Future Perspectives and Conclusion
Metastatic Bone pain Analyst Views
Metastatic Bone pain Key Companies
Appendix
Executive Summary
Metastatic Bone pain: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Metastatic Bone pain – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Metastatic Bone pain companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Metastatic Bone pain Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
QL1206: Qilu Pharmaceutical Co., Ltd.
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
AL2846: Chia Tai Tianqing Pharmaceutical Group Co., Ltd
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
JMT100: Yong Shun Technology Development
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Metastatic Bone pain Key Companies
Metastatic Bone pain Key Products
Metastatic Bone pain- Unmet Needs
Metastatic Bone pain- Market Drivers and Barriers
Metastatic Bone pain- Future Perspectives and Conclusion
Metastatic Bone pain Analyst Views
Metastatic Bone pain Key Companies
Appendix
LIST OF TABLES
Table 1 Total Products for Metastatic Bone pain
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Table 1 Total Products for Metastatic Bone pain
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
LIST OF FIGURES
Figure 1 Total Products for Metastatic Bone pain
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Figure 1 Total Products for Metastatic Bone pain
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
