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Global Breast Cancer Drug Market & Clinical Trial Insight 2025

January 2020 | 1140 pages | ID: G3A376B02564EN
PNS Pharma

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'Global Breast Cancer Drug Market & Clinical Trial Insight 2025' Report Highlights:
  • Global Breast Cancer Drug Market: US$ 40 Billion Opportunity
  • Global Breast Cancer Drug Clinical Pipeline: More Than 550 Drugs
  • Marketed Breast Cancer Drugs: More Than 90 Drugs
  • Comprehensive Clinical Insight & Patent Information
  • Drug Trials, Pricing, Dosage, Cancer Prevalence Insight: 130 Graphs/Charts
The applied science research has marked tremendous advancements in cutting off the epidemic cancer scenarios all around the world but every year unexpectedly more than one million new cases of breast cancer are reported. Breast cancer is somehow responsible for accounting about 10% of all the cancer cases worldwide. Although there has been a limitation in the treatment facilities for cancer cases but since few years there has been an excellent increase in the awareness level with regarding its impact on the survival rates in the case of early diagnosis of breast cancer.

'Global Breast Cancer Drug Market Offers US$ 40 Billion Market Opportunity Across Multiple Drug Classes Like Vaccines, Antibodies, Small Molecule, Peptides, Radiopharmaceuticals etc.'

The increasing cases of breast cancer have however opened a very prominent and novel opportunity for the market of breast cancer all over the world. Several therapies and products gets marketed under the category of breast cancer treatment market and some of these products or therapies include: chemotherapies, targeted therapies, hormonal therapies and many more. The unmet needs with respect to unconvincing safety data and severe adverse effects are however enhancing the realistic opportunities for the expansion of breast cancer drug market focused on improved efficacy and safety. The factors such as improved safety and efficacy are demanding the primary research focus from the R&D groups of the pharmaceutical companies.

“The pharmaceutical R&D groups are compelled to effectively unravel and understand the key dynamics of the market, competitive market, pipeline of the drug and the market forecast to better provide a realistic perspective of the market of breast cancer”

The participation of several major key players majorly towards the research and development of novel drugs is expected to develop the market of breast cancer drugs lucratively in the coming years. On an average, the engagement of the extensive research groups in developing the drugs for breast cancer calls for an unpredictable table of opportunities for them as well as the patients. The inevitable advancements with respect to customization and designing and the strong pipeline of the therapeutic agents are proving to be an effective treatment option than the already existing therapies.

High awareness, well established healthcare infrastructure are some of the factors that are however responsible for covering a large market share and owing to this, North America since few years is capable of holding the largest market share of global breast cancer drug market. Growing research and development investments and increasing incidence of breast cancer is adding to the conclusion that Europe is among the second largest market share of the global breast cancer drug market. Countries of Asia-Pacific are expected to be among the new additions for the breast cancer drug market in the next few years.

According to research report findings, the global breast cancer drug market is expected to rise upto many folds. Report gives in depths insight on multiple perspective of the breast cancer drug market and ongoing clinical trials. Each section of the report offers a deep insight view about the current market data, market drivers, trends and opportunities, drugs that are top-selling, major key players and the competitive outlook related to the market.

The data presented in the report covers all the market trends of the various geographic regions and the robust drug pipeline being followed by the country. In addition to this, the report also successfully provides the profile of the major companies participating in the development of the market. The secondary research included in the report is progressed through unpaid sources and open journals. The breast cancer drug market is expected to witness positive outlook in future driven by strong pipeline of drug candidates in clinical trials and availability of wide spectrum of drugs in the market.
1. INTRODUCTION TO BREAST CANCER DRUG MARKET

1.1 Overview
1.2 Historical Development of Breast Cancer Drugs

2. GLOBAL BREAST CANCER PREVALENCE & STATISTICS

2.1 North America
  2.1.1 United States
  2.1.2 Canada
2.2 Europe
  2.2.1 United Kingdom
2.2. Germany
  2.2.3 Russia
2.3 Asia-Pacific
  2.3.1 China
  2.3.2 India
  2.3.3 Japan
  2.3.4 South Korea
  2.3.5 Australia

3. AVAILABLE THERAPEUTICS FOR BREAST CANCER MANAGEMENT

3.1 Hormonal Therapy
  3.1.1 Aromatase Inhibitors
3.1. Estrogen Receptor Antagonist
  3.1.3 Selective Estrogen Receptor Modulators (SERMs)
  3.1.4 Gonadotropin Releasing Hormone Drugs
3.2 CDK 4/6 Inhibitors
3.3 HER2 Inhibitors
  3.3.1 Monoclonal antibodies
  3.3.2 Tyrosine Kinase Inhibitor
3.4 PI3K & mTOR Inhibitors
3.5 PARP Inhibitors
3.6 Other Therapeutics
  3.6.1 Immune Checkpoint Inhibitors
  3.6.2 Mitotic / Microtubule Inhibitors
  3.6.3 EGFR Inhibitors

4. BREAST CANCER THERAPEUTICS CLINICAL INSIGHT

4.1 Overview
4.2 Breast Cancer’s Clinical Trials by Drug Class & Phase
  4.2.1 CDK 4/6 Inhibitors Related Trials
  4.2.2 Hormonal Therapy Related Clinical Trials
  4.2.3 PARP Inhibitors Related Clinical Trials
  4.2.4 Other Targeted Therapeutic Related Clinical Trials
  4.2.5 Vaccines & Immunotherapeutics Related Clinical Trials
  4.2.6 HER2 Inhibitors Related Clinical Trials

5. GLOBAL BREAST CANCER DRUG CLINICAL PIPELINE INSIGHT

5.1 By Phase
5.2 By Country/Region
5.3 By Biomarker
5.4 By Formulation
5.5 By Company
5.6 By Mechanism

6. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: UNKNOWN

6.1 Overview
6.2 Clinical Pipeline Insight

7. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: RESEARCH PHASE

7.1 Overview
7.2 Clinical Pipeline Insight

8. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PRECLINICAL PHASE

8.1 Overview
8.2 Clinical Pipeline Insight

9. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: CLINICAL PHASE

9.1 Overview
9.2 Clinical Pipeline Insight

10. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PHASE-I

10.1 Overview
10.2 Clinical Pipeline Insight

11. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PHASE-I/II

11.1 Overview
11.2 Clinical Pipeline Insight

12. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PHASE-II

12.1 Overview
12.2 Clinical Pipeline Insight

13. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PHASE-II/III

13.1 Overview
13.2 Clinical Pipeline Insight

14. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PHASE-III

14.1 Overview
14.2 Clinical Pipeline Insight

15. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: PREREGISTRATION

15.1 Overview
15.2 Clinical Pipeline Insight

16. GLOBAL BREAST CANCER DRUG CLINICAL TRIAL INSIGHT: REGISTERED

16.1 Overview
16.2 Clinical Pipeline Insight

17. MARKETED BREAST CANCER DRUG CLINICAL INSIGHT BY COMPANY

18. COMPETITIVE LANDSCAPE

18.1 Novartis
18.2 Amgen
18.3 Eli Lilly
18.4 Merck
18.5 Pfizer
18.6 GlaxoSmithKline
18.7 Roche
18.8 Takeda Pharmaceuticals
18.9 Teva Pharmaceuticals
18.10 AstraZeneca
18.11 G1 Therapeutics
18.12 Nerviano Medical Science
18.13 Genentech

LIST OF FIGURES

Figure 1-1: Global - Incidence of Breast Cancer by Types (%), 2019
Figure 1-2: Global – Number of Total New Diagnosed Cancer Cases vs. Breast Cancer Cases (Million), 2018
Figure 1-3: Global – New Cases of Breast Cancer vs. Other Cancers (%), 2018
Figure 1-4: Global – Leading Cause of Cancer Related Death (Million), 2018
Figure 1-5: Global – Leading Causes of cancer Related Deaths (%), 2018
Figure 1-6: Global – Breast Cancer Cases vs. Other Cancers in Females (%), 2018
Figure 1-7: Global – Breast Cancer Drug Market Size (US$ Billion), 2019 - 2025
Figure 1-8: History of Breast Cancer in Ancient Period
Figure 1-9: Breast Cancer before 18th Century
Figure 1-10: Historical Development of Breast Cancer Drugs, 19th to 21st Century
Figure 2-1: US – Number of Newly Diagnosed Cases of Breast Cancer, 2016-2019 & 2025
Figure 2-2: US – Breast Cancer Cases in Women vs. Men, 2019
Figure 2-3: US – Breast Cancer Cases Women vs. Men (%), 2019
Figure 2-4: US – Breast Cancer Related Deaths in Males & Females, 2019
Figure 2-5: US – Probability of Breast Cancer Development in Males & Females (%), 2019
Figure 2-6: US – Share of Breast Cancer in Total Newly Diagnosed Cases of Cancer (%), 2019
Figure 2-7: US – 10 Year Probability of Female Breast Cancer by Age (%), 2018
Figure 2-8: US – States with Highest Breast Cancer Cases, 2019
Figure 2-9: US – States with Lowest Breast Cancer Cases, 2019
Figure 2-10: US – Breast Cancer Incidence Rate and Death Rate (per 100,000 People), 2011-2015
Figure 2-11: US – Current Breast Cancer Age-Specific Incidence Rate and Death Rate (per 100,000 People), 2018
Figure 2-12: US – Breast Cancer Incidence Rate by Race & Ethnicity (per 100,000 People), 2011-2015
Figure 2-13: US – Breast Cancer Death Rate by Race & Ethnicity (per 100,000 People), 2011-2015
Figure 2-14: US – Breast Cancer Incidence Rate by Type (per 100,000 People), 2010-2014
Figure 2-15: Canada – Number of Newly Diagnosed Cases of Different Cancers, 2019
Figure 2-16: Canada –Newly Diagnosed Cases of Different Cancers (%), 2019
Figure 2-17: Canada – Number of Breast Cancer Cases, 2017, 2019 & 2025
Figure 2-18: Canada – Number of Female & Male Breast Cancer Cases & Deaths, 2019
Figure 2-19: Canada – Breast Cancer Net Survival Rate in Males & Females (%), 2019
Figure 2-20: Canada – Female Breast Cancer Cases vs. Other Cancers in Females, 2019
Figure 2-21: Canada – Female Breast Cancer Cases vs. Other Cancers in Females (%), 2019
Figure 2-22: Canada – Breast Cancer Related deaths vs. Other Cancer Related Deaths in Females (%), 2019
Figure 2-23: Canada – Probability of Female Breast Cancer Incidence & Death (%), 2019
Figure 2-24: Canada – Breast Cancer Cases by Age (%), 2019
Figure 2-25: Canada – Female Breast Cancer Survival Rate by Age, 2019
Figure 2-26: Canada – Breast Cancer Cases by Stage (%), 2011-2015
Figure 2-27: UK – Number of Breast Cancer Cases, 2016, 2018 & 2025
Figure 2-28: UK – Number of Newly Diagnosed Cases of Different Cancers, 2019
Figure 2-29: UK – Average Number of Annual Male & Female Breast Cancer Cases, 2018
Figure 2-30: UK – Average Breast Cancer Cases by Country, 2018
Figure 2-31: UK – Average Breast Cancer Cases by Country (%), 2018
Figure 2-32: UK – Total Cancer Cases vs. Breast Cancer Cases in Females, 2018
Figure 2-33: UK - Total Cancer Cases vs. Breast Cancer Cases in Females (%), 2018
Figure 2-34: UK – Age Specific Incidence & Mortality Rate of Breast Cancer (Per 100,000 Cases), 2018
Figure 2-35: Germany – Number of Breast Cancer Cases & Deaths, 2018
Figure 2-36: Germany – Number of Newly Diagnosed Cases of Different Cancers, 2018
Figure 2-37: Germany – Breast Cancer Cases vs. Other Cancers (%), 2018
Figure 2-38: Germany – Breast Cancer Cases vs. Other Cancers Cases in Females (%), 2018
Figure 2-39: Germany – Incidence Rate & Death Rate of Breast Cancer (Per 100,000 People), 2018
Figure 2-40: Russia – Newly Diagnosed Breast Cancer Cases & Deaths, 2018
Figure 2-41: Russia – Newly Diagnosed Cases of Cancer by Types (%), 2018
Figure 2-42: Russia – Female Breast Cancer Cases Share in Total Newly Diagnosed Cancer Cases (%), 2017 & 2018
Figure 2-43: Russia – Age Specific Incidence & Death Rate of Breast Cancer (Per 100,000 People), 2018
Figure 2-44: China – Number of Newly Diagnosed cases of Different Cancers, 2018
Figure 2-45: China – Newly Diagnosed Breast Cancer Cases, 2015, 2018 & 2025
Figure 2-46: China – Breast Cancer Incidence & Death Rate, 2018
Figure 2-47: China – Number of Total Cancer Cases vs. breast cancer Cases in Females, 2018
Figure 2-48: China – Total Cancer Cases vs. breast cancer Cases in Females (%), 2018
Figure 2-49: China – Age Specific Incidence rate of Breast Cancer (Per 100,000 people), 2015-2019
Figure 2-50: India - Breast Cancer Cases, 2015, 2018 & 2025
Figure 2-51: India – Number of Breast Cancer Related Deaths, 2015, 2018 & 2025
Figure 2-52: India – Newly Diagnosed Cases of Different Type of Cancer (%), 2018
Figure 2-53: India – Probability of Breast Cancer Development in Females (%), 2018
Figure 2-54: India – Breast Cancer Age-Specific Incidence Rate & Death Rate (Per 100,000 People), 2018
Figure 2-55: India – Breast Cancer Cases by Age (%), 2018
Figure 2-56: Japan – Breast Cancer Cases, 2014, 2016 & 2018
Figure 2-57: Japan – Breast Cancer Related Deaths, 2014 & 2018
Figure 2-58: Japan – Newly Diagnosed Cases of Cancer by Type (%), 2018
Figure 2-59: Japan – Breast Cancer Cases vs. Other Cancers in Females (%), 2018
Figure 2-60: Japan - Age Standardized Breast Cancer Incidence Rate, 2014, 2018 & 2025
Figure 2-61: Japan - Age Standardized Breast Cancer Death Rate, 2014 & 2018
Figure 2-62: South Korea – Number of Breast Cancer Cases, 2016, 2018 & 2025
Figure 2-63: South Korea – Breast Cancer Cases vs. Other Cancers in Women (%), 2018
Figure 2-64: South Korea – Number of Male Breast Cancer Cases & Deaths, 2016
Figure 2-65: South Korea – Age Specific Incidence Rate of Breast Cancer (Per 100,000 People), 2016, 2018 & 2025
Figure 2-66: South Korea – Age Specific Mortality Rate of Breast Cancer (Per 100,000 People), 2016 & 2018
Figure 2-67: South Korea – 5 Year Survival Rate of Male & Female Breast Cancer (%), 2012-2016
Figure 2-68: South Korea – Breast Cancer Cases by Stage (%), 2015
Figure 2-69: Australia – Newly Diagnosed Breast Cancer Cases, 2018, 2019 & 2025
Figure 2-70: Australia – Breast Cancer Related Deaths, 2018 & 2019
Figure 2-71: Australia – Breast Cancer Cases vs. Other Cancers in Females, 2018
Figure 2-72: Australia – Breast Cancer Cases – Male & Female, 2019
Figure 2-73: Australia – Breast Cancer Deaths – Male & Female, 2019
Figure 2-74: Australia – Age Specific Breast Cancer Incidence & Death Rate, 2018
Figure 2-75: Australia - 5 year & 10 Year Survial Rate of Breast Cancer
Figure 2-76: Australia – Probability of Breast Cancer in Males & Females (%), 2018
Figure 3-1: Hormonal Therapy for Breast Cancer Treatment
Figure 3-2: Commercially Available Aromatase Inhibitors Drugs for Breast Cancer Management
Figure 3-3: Commercially Available Estrogen Receptor Antagonist Drugs for Breast Cancer Management
Figure 3-4: Commercially Available SERMs for Breast Cancer Management
Figure 3-5: Commercially Available Gonadotropin Releasing Hormone Analogues for Breast Cancer Management
Figure 3-6: Role of CDK 4/6 Inhibitors in Different Types of Breast Cancer
Figure 3-7: Types of HER2 Inhibitors for Breast Cancer Management
Figure 3-8: Commercially Available HER2 Targeting Monoclonal Antibodies for Breast Cancer
Figure 3-9: Commercially Available mTOR & PI3K Inhibitors for Breast Cancer Treatment
Figure 3-10: Commercially Available mTOR & PI3K Inhibitors for Breast Cancer Treatment
Figure 3-11: Commercially Available Immune Checkpoint Inhibitors for Breast Cancer Treatment
Figure 3-12: Commercially Available Mitotic/Microtubule Inhibitors for Breast Cancer Treatment
Figure 3-13: Commercially Available EGFR Inhibitors for Breast Cancer Treatment
Figure 4-1: Breast Cancer Related Active Clinical Trials – Total vs. Metastatic Breast Cancer Studies, October’2019
Figure 4-2: Discontinued Breast Cancer Trials – Suspended, Terminated & Withdrawn Trials, October’2019
Figure 4-3: Number of Discontinued, Completed & Unknown Status Clinical Studies, October 2019
Figure 4-4: Number of Clinical Trials by Treatment, October’2019
Figure 4-5: Number of Clinical Trials Related to Different Targeted Therapeutics, October’2019
Figure 4-6: Number of CDK 4/6 Inhibitors Related Clinical Trials against Breast Cancer, October’2019
Figure 4-7: Number of New CDK 4/6 Inhibitors in Different Phases of Clinical Trial, October’2019
Figure 4-8: New CDK inhibitors in Different Phases of Clinical Trial (%), October’2019
Figure 4-9: Hormonal Therapeutics Related Clinical Trials against Breast Cancer, October’2019
Figure 4-10: Number of PARP Inhibitors Related Clinical Trials against Breast Cancer, October’2019
Figure 4-11: Number of Other Targeted Therapy Related Clinical Trials against Breast Cancer, October’2019
Figure 4-12: Number of Vaccine & Immunotherapeutic Related Clinical Trials against Breast Cancer, October’2019
Figure 4-13: Number of HER2 Inhibitors Related Clinical Trials against Breast Cancer, October’2019
Figure 5 1: Global – Breast Cancer Clinical Pipeline by phase (Number), 2020 till 2025
Figure 5-2: Global – Breast Cancer Clinical Pipeline by phase (%), 2020 till 2025
Figure 5-3: Global - Breast Cancer Drug Pipeline by Region (Number), 2020 till 2025
Figure 5-4: Global - Breast Cancer Drug Pipeline by Country (Number), 2020 till 2025
Figure 5-5: Global - Breast Cancer Drug Pipeline by Biomarker (Number), 2020 till 2025
Figure 5-6: Global - Breast Cancer Drug Pipeline by Formulation (Number), 2020 till 2025
Figure 5-7: Global - Breast Cancer Drug Pipeline by Country (Number), 2020 till 2025
Figure 5-8: Global - Breast Cancer Drug Pipeline by Mechanism (Number), 2020 till 2025
Figure 6-1: Global Breast Cancer Drug Pipeline - Share of Unknown Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 7-1: Global Breast Cancer Drug Pipeline - Share of Research Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 8-1: Global Breast Cancer Drug Pipeline - Share of Preclinical Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 9-1: Global Breast Cancer Drug Pipeline - Share of Clinical Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 10-1: Global Breast Cancer Drug Pipeline - Share of Phase-I Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 11-1: Global Breast Cancer Drug Pipeline - Share of Phase-I/II Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 12-1: Global Breast Cancer Drug Pipeline - Share of Phase-II Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 13-1: Global Breast Cancer Drug Pipeline - Share of Phase-II/III Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 14-1: Global Breast Cancer Drug Pipeline - Share of Phase-III Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 15-1: Global Breast Cancer Drug Pipeline - Share of Preregistration Phase in Total Clinical Pipeline (%), 2020 till 2025
Figure 16-1: Global Breast Cancer Drug Pipeline - Share of Registration Phase in Total Clinical Pipeline (%), 2020 till 2025


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