Europe Constrained Peptide Drugs Market: Analysis and Forecast, 2024-2040
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Introduction to Europe constrained peptide drugs market
The market size is anticipated to be $0.06 billion in 2026 and is expected to reach $7.72 billion by 2040, growing at a CAGR of 41.55% during the forecast period 2026-2040. The constrained peptide drugs market is expected to experience significant growth, driven by innovative constrained peptide pipelines that now target more than just receptors. Advances in chemical technologies, the success of synthetic peptides in therapeutics, and their affordability across various diseases are also contributing to the projected growth in the forecast period.
Market Introduction
The Europe constrained peptide drugs market is poised for substantial growth in the coming years. One of the key drivers of this expansion is the region's robust pharmaceutical industry, characterized by a focus on research and development, innovation, and a strong regulatory framework. European pharmaceutical companies have been at the forefront of developing constrained peptide drugs, leveraging cutting-edge technologies and expertise in peptide chemistry.
Additionally, Europe has witnessed a growing demand for novel therapeutic approaches, particularly in the treatment of various diseases such as cancer, autoimmune disorders, and metabolic conditions. Constrained peptides offer a promising solution due to their specificity and potential for enhanced efficacy and safety profiles.
Furthermore, collaborative efforts between academia, research institutions, and pharmaceutical companies in Europe have accelerated the discovery and development of constrained peptide-based therapeutics. This collaborative ecosystem fosters innovation and positions Europe as a significant player in the constrained peptide drugs market.
Market Segmentation
Segmentation 1: by Country
Workflow/Innovation Strategy: Over the past decade, peptide drug discovery and development has witnessed a renaissance and scientific thrust as the industry has come to acknowledge the capability of peptide therapeutics in addressing unmet medical needs and the potential of this class of molecules to become a significant accompaniment or even favored alternative treatment to biologics and small molecules.
Peptide therapeutics have demonstrated a novel and selective yet safe mode of action for a wide range of indications. The existing and future development of constrained peptide drugs will continue to burgeon upon the strengths of constrained peptides and innovative technologies employed in the discovery and development, including peptide drug conjugates, multifunctional peptides, and cell-penetrating peptides. Furthermore, limitations associated with presently available peptides have resulted in an urgent need for new design, administration, and synthesis in peptide therapeutics, thereby leading to advancements in the development of constrained peptides.
Growth/Marketing Strategy: Constrained peptides provide noteworthy advantages over linear peptides. An increase in interest in constrained peptides due to their properties led to advancements in peptide synthesis technologies.
Competitive Strategy: Key players in the Europe constrained peptide drugs market have been analyzed and profiled in the study, including manufacturers involved in new product development, acquisitions, expansions, and strategic collaborations. Moreover, a detailed competitive benchmarking of the players operating in the Europe constrained peptide drugs market has been done to help the reader understand how players stack against each other, presenting a clear market landscape. Additionally, comprehensive competitive strategies such as partnerships, agreements, and collaborations will aid the reader in understanding the untapped revenue pockets in the market.
Introduction to Europe constrained peptide drugs market
The market size is anticipated to be $0.06 billion in 2026 and is expected to reach $7.72 billion by 2040, growing at a CAGR of 41.55% during the forecast period 2026-2040. The constrained peptide drugs market is expected to experience significant growth, driven by innovative constrained peptide pipelines that now target more than just receptors. Advances in chemical technologies, the success of synthetic peptides in therapeutics, and their affordability across various diseases are also contributing to the projected growth in the forecast period.
Market Introduction
The Europe constrained peptide drugs market is poised for substantial growth in the coming years. One of the key drivers of this expansion is the region's robust pharmaceutical industry, characterized by a focus on research and development, innovation, and a strong regulatory framework. European pharmaceutical companies have been at the forefront of developing constrained peptide drugs, leveraging cutting-edge technologies and expertise in peptide chemistry.
Additionally, Europe has witnessed a growing demand for novel therapeutic approaches, particularly in the treatment of various diseases such as cancer, autoimmune disorders, and metabolic conditions. Constrained peptides offer a promising solution due to their specificity and potential for enhanced efficacy and safety profiles.
Furthermore, collaborative efforts between academia, research institutions, and pharmaceutical companies in Europe have accelerated the discovery and development of constrained peptide-based therapeutics. This collaborative ecosystem fosters innovation and positions Europe as a significant player in the constrained peptide drugs market.
Market Segmentation
Segmentation 1: by Country
- Germany
- U.K.
- France
- Italy
- Spain
- Bicycle Therapeutics plc
- Spexis AG
- Santhera Pharmaceuticals
- Union Chimique Belge S.A. (UCB)
- Biosynth (Pepscan)
- Zealand Pharma
Workflow/Innovation Strategy: Over the past decade, peptide drug discovery and development has witnessed a renaissance and scientific thrust as the industry has come to acknowledge the capability of peptide therapeutics in addressing unmet medical needs and the potential of this class of molecules to become a significant accompaniment or even favored alternative treatment to biologics and small molecules.
Peptide therapeutics have demonstrated a novel and selective yet safe mode of action for a wide range of indications. The existing and future development of constrained peptide drugs will continue to burgeon upon the strengths of constrained peptides and innovative technologies employed in the discovery and development, including peptide drug conjugates, multifunctional peptides, and cell-penetrating peptides. Furthermore, limitations associated with presently available peptides have resulted in an urgent need for new design, administration, and synthesis in peptide therapeutics, thereby leading to advancements in the development of constrained peptides.
Growth/Marketing Strategy: Constrained peptides provide noteworthy advantages over linear peptides. An increase in interest in constrained peptides due to their properties led to advancements in peptide synthesis technologies.
Competitive Strategy: Key players in the Europe constrained peptide drugs market have been analyzed and profiled in the study, including manufacturers involved in new product development, acquisitions, expansions, and strategic collaborations. Moreover, a detailed competitive benchmarking of the players operating in the Europe constrained peptide drugs market has been done to help the reader understand how players stack against each other, presenting a clear market landscape. Additionally, comprehensive competitive strategies such as partnerships, agreements, and collaborations will aid the reader in understanding the untapped revenue pockets in the market.
Executive Summary
1 DEFINITION
1.1 Inclusion and Exclusion Criteria
2 RESEARCH SCOPE
2.1 Key Questions Answered in the Report
3 RESEARCH METHODOLOGY
3.1 Constrained Peptides: Research Methodology
3.2 Primary Data Sources
3.3 Secondary Data Sources
3.4 Market Estimation Model
3.5 Criteria for Company Profiling
4 MARKETS OVERVIEW
4.1 Introduction
4.1.1 Structure and Design of Constrained Peptides
4.1.2 Types of Constrained Peptides
4.2 Evolution of Constrained Peptides
4.3 Development of Constrained Peptides as Drugs
4.4 Potential Therapy Areas
4.5 Value Chain-Key Stakeholders
4.6 Key Industry Trends (by Region)
4.7 Key Industry Trends by Route of Administration
4.8 Key Industry Trends-Technological Advancements
4.9 Current Market Size and Growth Potential, $Billion, 2024-2040
4.1 COVID-19 Impact on Constrained Peptides Drugs Market
4.10.1 Impact on Constrained Peptide Drugs Companies
4.10.2 Clinical Trial Disruptions and Resumptions
5 EUROPE
5.1 Constrained Peptide Drugs Market (by Country), $Billion, 2024-2031
5.1.1 Europe
5.1.1.1 U.K.
5.1.1.2 Germany
5.1.1.3 France
5.1.1.4 Italy
5.1.1.5 Spain
6 COMPANY PROFILES
6.1 Overview
6.2 Bicycle Therapeutics plc
6.2.1 Company Overview
6.2.2 Role of Bicycle Therapeutics plc in the Constrained Peptide Drugs Market
6.2.1 Current Status and Policies for Investigational Drugs
6.2.2 Key Competitors of the Company
6.2.3 Financials
6.2.4 Key Insights about the Financial Health of the Company
6.2.5 Corporate Strategies
6.2.5.1 Synergistic Activities
6.2.5.2 Funding
6.2.6 Business Strategies
6.2.6.1 Clinical Developments
6.2.6.2 Regulatory and Legal
6.2.7 Analyst Perspective
6.3 Spexis AG
6.3.1 Company Overview
6.3.2 Role of Spexis AG in the Constrained Peptide Drugs Market
6.3.3 Current Status and Policies for Investigational Drugs
6.3.4 Key Competitors of the Company
6.3.5 Financials
6.3.6 Key Insights about the Financial Health of the Company
6.3.7 Corporate Strategies
6.3.7.1 Funding
6.3.7.2 Mergers and Acquisitions
6.3.7.3 Synergistic activities
6.3.8 Business Strategies
6.3.8.1 Regulatory and Legal
6.3.9 Analyst Perspective
6.4 Santhera Pharmaceuticals
6.4.1 Company Overview
6.4.2 Role of Santhera Pharmaceuticals in the Constrained Peptide Drugs Market
6.4.3 Current Status and Policies for Investigational Drugs
6.4.4 Key Competitors of the Company
6.4.5 Financials
6.4.6 Corporate Strategies
6.4.6.1 Funding
6.4.7 Business Strategies
6.4.7.1 Clinical Developments
6.4.8 Analyst Perspective
6.5 Union Chimique Belge S.A. (UCB)
6.5.1 Company Overview
6.5.2 Role of Union Chimique Belge S.A. (UCB) in the Constrained Peptide Drugs Market
6.5.3 Current Status and Policies for Investigational Drugs
6.5.4 Key Competitors of the Company
6.5.5 Financials
6.5.6 Key Insights about the Financial Health of the Company
6.5.7 Corporate Strategies
6.5.7.1 Mergers and Acquisitions
6.5.8 Business Strategies
6.5.8.1 Clinical Developments
6.5.8.2 Regulatory and legal
6.5.9 Analyst Perspective
6.6 Biosynth (Pepscan)
6.6.1 Company Overview
6.6.2 Role of Biosynth (Pepscan) in the Constrained Peptide Drugs Market
6.6.3 Key Competitors of the Company
6.6.4 Corporate Strategies
6.6.4.1 License
6.6.5 Business Strategies
6.6.5.1 Product Launch
6.6.6 Analyst Perspective
6.6.7 Zealand Pharma
6.6.7.1 ZP10000 (Preclinical)
6.6.7.1.1 Product Profile
1 DEFINITION
1.1 Inclusion and Exclusion Criteria
2 RESEARCH SCOPE
2.1 Key Questions Answered in the Report
3 RESEARCH METHODOLOGY
3.1 Constrained Peptides: Research Methodology
3.2 Primary Data Sources
3.3 Secondary Data Sources
3.4 Market Estimation Model
3.5 Criteria for Company Profiling
4 MARKETS OVERVIEW
4.1 Introduction
4.1.1 Structure and Design of Constrained Peptides
4.1.2 Types of Constrained Peptides
4.2 Evolution of Constrained Peptides
4.3 Development of Constrained Peptides as Drugs
4.4 Potential Therapy Areas
4.5 Value Chain-Key Stakeholders
4.6 Key Industry Trends (by Region)
4.7 Key Industry Trends by Route of Administration
4.8 Key Industry Trends-Technological Advancements
4.9 Current Market Size and Growth Potential, $Billion, 2024-2040
4.1 COVID-19 Impact on Constrained Peptides Drugs Market
4.10.1 Impact on Constrained Peptide Drugs Companies
4.10.2 Clinical Trial Disruptions and Resumptions
5 EUROPE
5.1 Constrained Peptide Drugs Market (by Country), $Billion, 2024-2031
5.1.1 Europe
5.1.1.1 U.K.
5.1.1.2 Germany
5.1.1.3 France
5.1.1.4 Italy
5.1.1.5 Spain
6 COMPANY PROFILES
6.1 Overview
6.2 Bicycle Therapeutics plc
6.2.1 Company Overview
6.2.2 Role of Bicycle Therapeutics plc in the Constrained Peptide Drugs Market
6.2.1 Current Status and Policies for Investigational Drugs
6.2.2 Key Competitors of the Company
6.2.3 Financials
6.2.4 Key Insights about the Financial Health of the Company
6.2.5 Corporate Strategies
6.2.5.1 Synergistic Activities
6.2.5.2 Funding
6.2.6 Business Strategies
6.2.6.1 Clinical Developments
6.2.6.2 Regulatory and Legal
6.2.7 Analyst Perspective
6.3 Spexis AG
6.3.1 Company Overview
6.3.2 Role of Spexis AG in the Constrained Peptide Drugs Market
6.3.3 Current Status and Policies for Investigational Drugs
6.3.4 Key Competitors of the Company
6.3.5 Financials
6.3.6 Key Insights about the Financial Health of the Company
6.3.7 Corporate Strategies
6.3.7.1 Funding
6.3.7.2 Mergers and Acquisitions
6.3.7.3 Synergistic activities
6.3.8 Business Strategies
6.3.8.1 Regulatory and Legal
6.3.9 Analyst Perspective
6.4 Santhera Pharmaceuticals
6.4.1 Company Overview
6.4.2 Role of Santhera Pharmaceuticals in the Constrained Peptide Drugs Market
6.4.3 Current Status and Policies for Investigational Drugs
6.4.4 Key Competitors of the Company
6.4.5 Financials
6.4.6 Corporate Strategies
6.4.6.1 Funding
6.4.7 Business Strategies
6.4.7.1 Clinical Developments
6.4.8 Analyst Perspective
6.5 Union Chimique Belge S.A. (UCB)
6.5.1 Company Overview
6.5.2 Role of Union Chimique Belge S.A. (UCB) in the Constrained Peptide Drugs Market
6.5.3 Current Status and Policies for Investigational Drugs
6.5.4 Key Competitors of the Company
6.5.5 Financials
6.5.6 Key Insights about the Financial Health of the Company
6.5.7 Corporate Strategies
6.5.7.1 Mergers and Acquisitions
6.5.8 Business Strategies
6.5.8.1 Clinical Developments
6.5.8.2 Regulatory and legal
6.5.9 Analyst Perspective
6.6 Biosynth (Pepscan)
6.6.1 Company Overview
6.6.2 Role of Biosynth (Pepscan) in the Constrained Peptide Drugs Market
6.6.3 Key Competitors of the Company
6.6.4 Corporate Strategies
6.6.4.1 License
6.6.5 Business Strategies
6.6.5.1 Product Launch
6.6.6 Analyst Perspective
6.6.7 Zealand Pharma
6.6.7.1 ZP10000 (Preclinical)
6.6.7.1.1 Product Profile
LIST OF FIGURES
Figure 1: Europe Total Number of Drugs Approved by the U.S. FDA, 2016-2021
Figure 2: Europe Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 3: Europe Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 4: Europe Constrained Peptide Drugs: Impact Analysis
Figure 5: Constrained Peptide Drugs Market (by Region), $Billion, 2024-2040
Figure 6: Constrained Peptide Drugs Methodology
Figure 7: Primary Research Methodology
Figure 8: Epidemiology-Based Approach
Figure 9: Inducing Conformational Effects
Figure 10: Two Main Types of Constraints
Figure 11: Methodology for Restricting Conformation in Peptides
Figure 12: Types of Constrained Peptides
Figure 13: Key Milestones in the Evolution of Constrained Peptides
Figure 14: Major Factors Affecting Constrained Peptide Development
Figure 15: Value Chain Analysis- Key Stakeholders
Figure 16: Constrained Peptide Drugs Market (by Region), $Billion, 2024-2031
Figure 17: Constrained Peptide Drugs Market (by Region), $Billion, 2032-2040
Figure 18: Europe Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 19: Europe Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 20: Constrained Peptide Drugs Market (by Region)
Figure 21: Constrained Peptide Drugs Market (by Region), $Billion, 2024-2040
Figure 22: Europe Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 23: Europe Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 24: Europe: Market Dynamics
Figure 25: Europe Constrained Peptide Drugs Market (by Country), $Billion, 2025 and 2040
Figure 26: U.K. Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 27: U.K. Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 28: Germany Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 29: Germany Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 30: France Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 31: France Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 32: Italy Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 33: Italy Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 34: Spain Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 35: Spain Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 36: Total Number of Companies Profiled
Figure 37: Bicycle Therapeutics plc: Product Portfolio
Figure 38: Bicycle Therapeutics plc: Overall Financials, $Million, 2019-2021
Figure 39: Bicycle Therapeutics plc: Revenue (by Region), $Million, 2019-2021
Figure 40: Bicycle Therapeutics plc: R&D Expenditure, $Million, 2019-2021
Figure 41: Spexis AG: Product Portfolio
Figure 42: Spexis AG: Overall Financials, $Million, 2019-2021
Figure 43: Spexis AG: R&D Expenditure, $Million, 2019-2021
Figure 44: Santhera Pharmaceuticals: Product Portfolio
Figure 45: Santhera Pharmaceuticals: Overall Financials, $Million, 2019-2021
Figure 46: Union Chimique Belge S.A. (UCB): Product Portfolio
Figure 47: Union Chimique Belge S.A. (UCB): Overall Financials, $Million, 2019-2021
Figure 48: Union Chimique Belge S.A. (UCB): R&D Expenditure, $Million, 2019-2021
Figure 49: Biosynth (Pepscan): Product Portfolio
Figure 1: Europe Total Number of Drugs Approved by the U.S. FDA, 2016-2021
Figure 2: Europe Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 3: Europe Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 4: Europe Constrained Peptide Drugs: Impact Analysis
Figure 5: Constrained Peptide Drugs Market (by Region), $Billion, 2024-2040
Figure 6: Constrained Peptide Drugs Methodology
Figure 7: Primary Research Methodology
Figure 8: Epidemiology-Based Approach
Figure 9: Inducing Conformational Effects
Figure 10: Two Main Types of Constraints
Figure 11: Methodology for Restricting Conformation in Peptides
Figure 12: Types of Constrained Peptides
Figure 13: Key Milestones in the Evolution of Constrained Peptides
Figure 14: Major Factors Affecting Constrained Peptide Development
Figure 15: Value Chain Analysis- Key Stakeholders
Figure 16: Constrained Peptide Drugs Market (by Region), $Billion, 2024-2031
Figure 17: Constrained Peptide Drugs Market (by Region), $Billion, 2032-2040
Figure 18: Europe Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 19: Europe Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 20: Constrained Peptide Drugs Market (by Region)
Figure 21: Constrained Peptide Drugs Market (by Region), $Billion, 2024-2040
Figure 22: Europe Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 23: Europe Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 24: Europe: Market Dynamics
Figure 25: Europe Constrained Peptide Drugs Market (by Country), $Billion, 2025 and 2040
Figure 26: U.K. Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 27: U.K. Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 28: Germany Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 29: Germany Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 30: France Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 31: France Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 32: Italy Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 33: Italy Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 34: Spain Constrained Peptide Drugs Market, $Billion, 2024-2031
Figure 35: Spain Constrained Peptide Drugs Market, $Billion, 2032-2040
Figure 36: Total Number of Companies Profiled
Figure 37: Bicycle Therapeutics plc: Product Portfolio
Figure 38: Bicycle Therapeutics plc: Overall Financials, $Million, 2019-2021
Figure 39: Bicycle Therapeutics plc: Revenue (by Region), $Million, 2019-2021
Figure 40: Bicycle Therapeutics plc: R&D Expenditure, $Million, 2019-2021
Figure 41: Spexis AG: Product Portfolio
Figure 42: Spexis AG: Overall Financials, $Million, 2019-2021
Figure 43: Spexis AG: R&D Expenditure, $Million, 2019-2021
Figure 44: Santhera Pharmaceuticals: Product Portfolio
Figure 45: Santhera Pharmaceuticals: Overall Financials, $Million, 2019-2021
Figure 46: Union Chimique Belge S.A. (UCB): Product Portfolio
Figure 47: Union Chimique Belge S.A. (UCB): Overall Financials, $Million, 2019-2021
Figure 48: Union Chimique Belge S.A. (UCB): R&D Expenditure, $Million, 2019-2021
Figure 49: Biosynth (Pepscan): Product Portfolio
LIST OF TABLES
Table 1: Potential Indications of Constrained Peptide Drugs
Table 2: Potential Therapy Areas of Constrained Peptide Drugs
Table 3: Route of Administration of Constrained Peptide Drugs
Table 4: Impact of COVID-19 on Constrained Peptide Drug Companies
Table 1: Potential Indications of Constrained Peptide Drugs
Table 2: Potential Therapy Areas of Constrained Peptide Drugs
Table 3: Route of Administration of Constrained Peptide Drugs
Table 4: Impact of COVID-19 on Constrained Peptide Drug Companies
