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DNA and Gene Cloning Services Market – Distribution by Type of Service Offered (Gene Synthesis, Custom Cloning, Sub-cloning and Others), Type of Gene (Standard Gene, Complex Gene and Others), Company Size (Small, Mid-sized and Large), End-User Industry (Academic and R&D, Pharmaceutical and Biotechnology Companies, and Others) and Key Geographies (North America, Europe, Asia-Pacific, Latin America and MENA): Industry Trends and Global Forecasts, 2022-2035

August 2022 | 228 pages | ID: D2597179F4BCEN
Roots Analysis

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The projected value of DNA and gene cloning market is expected to be valued at USD 2,100 million in 2022 and is anticipated to grow at a CAGR of 16% during the forecast period 2022-2035.

In 1973, a pivotal scientific breakthrough occurred when a group of researchers demonstrated the isolation and cloning of individual genes through the enzymatic cleavage of DNA into fragments. This milestone marked the inception of DNA and gene cloning, subsequently evolving into a fundamental tool for genetic research. The ongoing progress in genetic engineering and cloning techniques has facilitated genome alterations in microorganisms, leading to the production of substances with diverse applications in research and therapeutics.

The ramifications of gene cloning extend to the development of gene therapies aimed at addressing serious medical conditions such as cystic fibrosis, cancer, and AIDS. Remarkably, gene cloning presents a potential remedy for organ scarcity and plays a crucial role in the synthesis of antibiotics, vitamins, and hormones. Recognizing the multifaceted applications of DNA and gene cloning, scientists have undertaken initiatives to construct gene libraries housing a comprehensive collection of cloned DNA.

However, the successful implementation of DNA and gene cloning is not without its challenges. Issues such as gene toxicity, the necessity for specific insert sizes or large vectors, unstable DNA elements, and the presence of DNA secondary structures pose hurdles in achieving seamless cloning processes. To surmount these obstacles and ensure the production of high-quality and stable outcomes, companies engaged in DNA and gene cloning are increasingly turning to outsourcing as a preferable solution among other alternatives.

Presently, the landscape of DNA cloning and gene cloning services is characterized by a highly fragmented market, featuring a diverse array of players ranging from start-ups to mid-sized firms and well-established entities. These entities offer a comprehensive spectrum of services employing various cloning methods. Noteworthy is the significant research focus on DNA cloning technologies, evident from the publication of over 6,900 research articles in recent years. Moreover, more than 35 global events have been organized to delve into the latest trends associated with DNA and gene cloning.

Driven by escalating demand for gene therapies and the introduction of novel, advanced DNA cloning technologies, the DNA cloning and gene cloning services market is poised for steady growth during the forecast period. This trajectory reflects the increasing significance of cloning services in advancing scientific and medical frontiers.

Research Coverage
  • A comprehensive overview of DNA cloning, covering methods (e.g., PCR, Ligation Independent Cloning), techniques, gene types, expression systems, and cloning vectors. It also delves into applications, challenges, and the rationale for outsourcing.
  • The current market landscape, evaluating providers based on parameters like establishment year, size, and services offered, including gene synthesis and custom cloning.
  • A benchmark analysis of DNA and gene cloning service providers in North America, Europe, Asia-Pacific, and Rest of the World, comparing capabilities using various parameters.
  • Detailed profiles of key players in DNA and gene cloning services, encompassing company overviews, financial information, service portfolios, and recent developments.
  • Patents related to DNA and gene cloning since 2017, considering parameters like patent type, geographical location, and leading players.
  • Reviews over 6,900 peer-reviewed articles on DNA and gene cloning published between 2018 and 2022, examining parameters such as publication year and key focus areas.
  • Recent events related to DNA and gene cloning, considering factors like event type, geographical distribution, and emerging agendas.
  • A market forecast analysis until 2035, segmented by service type, gene type, company size, end-user industry, and geographical regions.
  • A case study on DNA cloning kits developers, detailing kit components, cloning methods, and geographical distribution. It also covers DNA cloning reagents developers.
Key Market Companies
  • Aragen Life Sciences
  • Bio-Techne
  • Charles River Laboratories
  • Curia
  • Eurofins
  • GenScript
  • Integrated DNA Technologies
  • MedGenome
  • Sino Biological
  • Syngene
  • Twist Bioscience
1. PREFACE

1.1. Scope of the Report
1.2. Market Segmentation
1.3. Research Methodology
1.4. Key Questions Answered
1.5. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION

3.1. Chapter Overview
3.2. Introduction to DNA Cloning
3.3. Methods of DNA Cloning
  3.3.1. Restriction Enzyme Based Cloning
  3.3.2. PCR Cloning
  3.3.3. Ligation Independent Cloning
  3.3.4. TA Cloning
  3.3.5. Blunt End Cloning
  3.3.6. Seamless Cloning
  3.3.7. Recombinational Cloning
3.4. Techniques Used in DNA and Gene Cloning
  3.4.1. Molecular Cloning
  3.4.2. Genetic Synthesis
  3.4.3. Custom Cloning
3.5. Types of Genes Cloned
  3.5.2. Standard Genes
  3.5.3. Complex Genes
3.6. Type of Expression Systems Used in DNA and Gene Cloning
  3.6.1. Mammalian Expression System
  3.6.2. Insect Expression System
  3.6.3. Bacterial Expression System
  3.6.4. Plant Expression System
  3.6.5. Yeast Expression System
3.7. Cloning Vectors
  3.7.1. Plasmids
  3.7.2. Bacteriophages
  3.7.3. Bacterial Artificial Chromosomes (BACs)
  3.7.4. Yeast Artificial Chromosomes (YACs)
  3.7.5. Mammalian Artificial Chromosomes (MACs)
3.8. Applications of DNA and Gene Cloning
  3.8.1. Gene Synthesis
  3.8.2. Gene Expression
  3.8.3. Vaccine Research
  3.8.4. Gene Therapy
  3.8.5. Genomic Library
3.9. Challenges associated with DNA and Gene Cloning
3.10. Outsourcing of DNA and Gene Cloning Services
3.11. Future Perspectives

4. MARKET LANDSCAPE: DNA AND GENE CLONING SERVICE PROVIDERS

4.1. Chapter Overview
4.2. DNA and Gene Cloning Service Providers Landscape
  4.2.1. Analysis by Year of Establishment
  4.2.2. Analysis by Company Size
  4.2.3. Analysis by Region of Headquarters
  4.2.4. Analysis by Company Size and Region of Headquarters
4.3. DNA and Gene Cloning Services: Overall Market Landscape
  4.3.1. Analysis by Type of Service(s) Offered
  4.3.2. Analysis by Cloning Method(s) Used
  4.3.3. Analysis by Type of Gene(s) Cloned
  4.3.4. Analysis by Expression System(s) Used
  4.3.5. Analysis by Cloning Vector(s) Used
  4.3.6. Analysis by End User

5. BENCHMARK ANALYSIS

5.1. Chapter Overview
5.2. Assumptions and Key Parameters
5.3. Methodology
5.4. Benchmark Analysis: Peer Groups
  5.4.1. Benchmark Analysis: North America (Peer Group I)
  5.4.2. Benchmark Analysis: North America (Peer Group II)
  5.4.3. Benchmark Analysis: North America (Peer Group III)
  5.4.4. Benchmark Analysis: Europe (Peer Group IV)
  5.4.5. Benchmark Analysis: Europe (Peer Group V)
  5.4.6. Benchmark Analysis: Asia-Pacific and Rest of the World (Peer Group VI)
  5.4.7. Benchmark Analysis: Asia-Pacific and Rest of the World (Peer Group VII)

6. COMPANY PROFILES

6.1. Chapter Overview
6.2. Aragen Life Sciences
  6.2.1. Company Overview
  6.2.2. Service Portfolio
  6.2.3. Recent Developments and Future Outlook
6.3. Bio-Techne
  6.3.1. Company Overview
  6.3.2. Financial Information
  6.3.3. Service Portfolio
  6.3.4. Recent Developments and Future Outlook
6.4. Charles River Laboratories
  6.4.1. Company Overview
  6.4.2. Financial Information
  6.4.3. Service Portfolio
  6.4.4. Recent Developments and Future Outlook
6.5. Curia
  6.5.1. Company Overview
  6.5.2. Service Portfolio
  6.5.3. Recent Developments and Future Outlook
6.6. Eurofins
  6.6.1. Company Overview
  6.6.2. Financial Information
  6.6.3. Service Portfolio
  6.6.4. Recent Developments and Future Outlook
6.7. GenScript
  6.7.1. Company Overview
  6.7.2. Financial Information
  6.7.3. Service Portfolio
  6.7.4. Recent Developments and Future Outlook
6.8. Integrated DNA Technologies
  6.8.1. Company Overview
  6.8.2. Service Portfolio
  6.8.3. Recent Developments and Future outlook
6.9. MedGenome
  6.9.1. Company Overview
  6.9.2. Service Portfolio
  6.9.3. Recent Developments and Future Outlook
6.10. Sino Biological
  6.10.1. Company Overview
  6.10.2. Service Portfolio
  6.10.3. Recent Developments and Future Outlook
6.11. Syngene
  6.11.1. Company Overview
  6.11.2. Financial Information
  6.11.3. Service Portfolio
  6.11.4. Recent Developments and Future Outlook
6.12. Twist Bioscience
  6.12.1. Company Overview
  6.12.2. Financial Information
  6.12.3. Service Portfolio
  6.12.4. Recent Developments and Future Outlook

7. PATENT ANALYSIS

7.1. Chapter Overview
7.2. Scope and Methodology
7.3. DNA and Gene Cloning: Patent Analysis
  7.3.1. Analysis by Publication Year
  7.3.2. Analysis by Application Year
  7.3.3. Analysis by Annual Number of Granted Patents and Patent Applications
  7.3.4. Analysis by Geographical Location
  7.3.5. Analysis by CPC Symbols
  7.3.6. Analysis by Focus Area
  7.3.7. Analysis by Type of Applicant
  7.3.8. Leading Players: Analysis by Number of Patents
  7.3.9. Leading Individual Assignees: Analysis by Number of Patents
7.4. DNA and Gene Cloning: Patent Benchmarking Analysis
  7.4.1. Analysis by Patent Characteristics
7.5. DNA and Gene Cloning: Patent Valuation Analysis
7.6. Leading Patents by Number of Citations

8. PUBLICATION ANALYSIS

8.1. Chapter Overview
8.2. Scope and Methodology
  8.2.1. Analysis by Year of Publication
  8.2.2. Analysis by Type of Cloning
  8.2.3. Word Cloud: Emerging Focus Areas
  8.2.4. Popular Journals: Analysis by Number of Publications
  8.2.5. Leading Authors: Analysis by Number of Publications
  8.2.6. Leading First Authors: Analysis by Number of Publications

9. GLOBAL EVENT ANALYSIS

9.1. Chapter Overview
9.2. Scope and Methodology
9.3. List of Global Events related to DNA and Gene Cloning
  9.3.1. Analysis by Year of Event
  9.3.2. Analysis by Event Platform
  9.3.3. Analysis by Type of Event
  9.3.4. Analysis by Geography
  9.3.5. Word Cloud: Evolutionary Trends in Event Agenda / Key Focus Area
  9.3.6. Most Active Participants: Analysis by Number of Events
  9.3.7. Analysis by Seniority Level of Event Speakers
  9.3.8. Geographical Mapping of Upcoming Events

10. MARKET FORECAST

10.1. Chapter Overview
10.2. Forecast Methodology and Key Assumptions
10.3. Global DNA and Gene Cloning Services Market, 2022-2035
  10.3.1. DNA and Gene Cloning Services Market, 2022 and 2035: Distribution by Services Offered
    10.3.1.1. DNA and Gene Cloning Services Market for Gene Synthesis, 2022-2035
    10.3.1.2. DNA and Gene Cloning Services Market for Custom Cloning, 2022-2035
    10.3.1.3. DNA and Gene Cloning Services Market for Sub-cloning, 2022-2035
    10.3.1.4. DNA and Gene Cloning Services Market for Other Services, 2022-2035
  10.3.2. DNA and Gene Cloning Services Market, 2022 and 2035: Distribution by Type of Genes Cloned
    10.3.2.1. DNA and Gene Cloning Services Market for Standard Gene, 2022-2035
    10.3.2.2. DNA and Gene Cloning Services Market for Complex Gene, 2022-2035
    10.3.2.3. DNA and Gene Cloning Services Market for Other Genes, 2022-2035
  10.3.3. DNA and Gene Cloning Services Market, 2022 and 2035: Distribution by Company Size
    10.3.3.1. DNA and Gene Cloning Services Market for Small Companies, 2022-2035
    10.3.3.2. DNA and Gene Cloning Services Market for Mid-sized Companies, 2022-2035
    10.3.3.3. DNA and Gene Cloning Services Market for Large Companies, 2022-2035
  10.3.4. DNA and Gene Cloning Services Market, 2022 and 2035: Distribution by End User Industry
    10.3.4.1. DNA and Gene Cloning Services Market for Academic and R&D, 2022-2035
    10.3.4.2. DNA and Gene Cloning Services Market for Pharmaceutical and Biotechnology Companies, 2022-2035
    10.3.4.3. DNA and Gene Cloning Services Market for Other End Users, 2022-2035
  10.3.5. DNA and Gene Cloning Services Market, 2022 and 2035: Distribution by Key Geographical Regions
    10.3.5.1. DNA and Gene Cloning Services Market in North America, 2022-2035
    10.3.5.2. DNA and Gene Cloning Services Market in Europe, 2022-2035
    10.3.5.3. DNA and Gene Cloning Services Market in Asia-Pacific, 2022-2035
    10.3.5.4. DNA and Gene Cloning Services Market in Latin America, 2022-2035
    10.3.5.5. DNA and Gene Cloning Services Market in MENA, 2022-2035

11. CASE STUDY: DNA AND GENE CLONING KITS AND REAGENTS

11.1. Chapter Overview
11.2. DNA Cloning Kits
  11.2.1. Analysis by Kit Components
  11.2.2. Analysis by Number of Reactions
  11.2.3. Analysis by Type of Cloning Method Used
  11.2.4. Analysis by Type of Fragment(s) Cloned
  11.2.5. Analysis by Cloning Time
  11.2.6. Analysis by Efficacy
  11.2.7. Analysis by Kit Shelf Life
11.3. DNA Cloning Reagents
  11.3.1. Analysis by Unit Size
  11.3.2. Analysis by Reagent Concentration
  11.3.3. Analysis by Reagent Components
  11.3.4. Analysis by Exonuclease Activity
  11.3.5. Analysis by Product Overhangs
  11.3.6. Analysis by Heat Inactivation Temperature
  11.3.7. Analysis by Storage Temperature
11.4. Players in North America
  11.4.1. DNA Cloning Kit Developers
  11.4.2. DNA Cloning Reagent Developers
  11.4.3. DNA Cloning Service Providers
11.5. Players in Europe
  11.5.1. DNA Cloning Kit Developers
  11.5.2. DNA Cloning Reagent Developers
  11.5.3. DNA Cloning Service Providers
11.6. Players in Asia-Pacific and Rest of the World
  11.6.1. DNA Cloning Kit Developers
  11.6.2. DNA Cloning Reagent Developers
  11.6.3. DNA Cloning Service Providers

12. CONCLUDING REMARKS

13. EXECUTIVE INSIGHTS

14. APPENDIX I: TABULATED DATA

15. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS


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