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Alzheimer's Disease Therapeutics and Diagnostics: World Market 2013-2023

June 2013 | 149 pages | ID: AB158048079EN
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Alzheimer's medicine - your guide to technologies, trends and revenues

Where's treatment of Alzheimer's disease heading? Visiongain's new report gives you revenue predictions for those drugs and diagnostic tests from 2013, helping you stay ahead.

There you find financial data, R&D trends, opportunities, and prospects. In particular, you see forecasted sales to 2023 at overall world market, submarket, product, and national level.

Read on, then, to explore that industry and see what its future market could be worth.

Forecasts to 2023 and other analyses to help you stay ahead

Besides revenue forecasting to 2023, you find historical data, growth rates, and market shares. You assess quantitative and qualitative analysis, business news, outlooks, and developments (R&D). You also gain 40 tables, 63 charts, and an interview.

Many opportunities exist for diagnosis and treatment of Alzheimer's. Our study shows you the most promising and lucrative parts of that CNS market, helping you stay ahead. Now see how you can benefit your research, analyses and decisions, also saving time.

Finding data you need on that neurodegenerative disorder has just got easier. The following sections show how you benefit from our new analysis.

Discover outlooks for the world market and submarkets

Along with prediction of overall world market value to 2023, our report shows you revenue forecasting for main submarkets at world level:
  • Medicines for Alzheimer's disease
  • Diagnostics for Alzheimer's (including biomarkers).
Also our study discusses what stimulates and restrains that market. That analysis helps you identify potential and find ways for your business to develop. Assess brands too.

See forecasts for Alzheimer's drugs

How will drugs perform to 2023 at world level? Our study predicts individual revenues of three products:
  • Namenda
  • Aricept
  • Exelon.
There you discover how high sales can go, to 2023. You see what's happening, then, understanding trends, competition, challenges, and opportunities.

You find geographical revenue predictions too.

Discover prospects of national markets for those anti-dementia products

Developments worldwide expand the market for diagnosing, treating and monitoring neurodegenerative disorders. Developed and developing national markets hold high potential from 2013.

Our analyses show you individual revenue forecasts to 2023 for nine national markets and a regional block:
  • US
  • Japan
  • Germany, France, UK, Italy, and Spain (EU5)
  • Europe (grouped forecast)
  • India and China.
There you find potential. Large companies and specialty biopharma and diagnostics firms face many opportunities. Our study explains, assessing developments to help your work.

What affects producers of those diagnostic tests and medicines?

Our report discusses issues and events affecting that industry and market from 2013, including these:
  • Research and development (R&D) - drugs, diagnostic tests, and related technologies
  • Disease prevalence - expanding patient populations
  • Disease-modifying drugs and obstacles to cures
  • Regulatory guidelines - changes and opportunities.
The study also discusses other aspects of diagnosing and treating Alzheimer's:
  • Needs for Alzheimer's treatments
  • Drugs and related technologies to transform the market
  • Biomarkers and diagnostic imaging technologies, including structural, functional, and molecular imaging
  • Deep brain stimulation (functional neuromodulation)
  • Intellectual property (IP), licensing agreements and partnerships.
That way, you explore the industry's strengths, weaknesses, opportunities, and threats. You also analyse it through Porter's five forces.

See, then, what the future holds.

Prominent companies in that biomedical field and 2017 market value

Our new study predicts the world market for Alzheimer's products will reach $8.3bn in 2017, and expand fast - especially from 2018.

Disease-modifying therapies will transform that market. New drugs hold great potential from 2018 to 2023, given the prevalence of Alzheimer's and needs for more-effective treatments.

Our work thus shows you what technologies, products, and organisations hold greatest potential. In particular, the analysis investigates these companies:
  • Pfizer
  • Eisai
  • Forest Laboratories
  • Lundbeck
  • Novartis
  • TauRx Therapeutics
  • AC Immune.
There you assess results, product ranges, R&D pipelines, and outlooks.

Prospects for Alzheimer's products and R&D are strong, and from 2013 there will arise many opportunities. Our work shows you the possibilities there, helping you stay ahead.

Eight ways Alzheimer's Disease Therapeutics and Diagnostics: World Market 2013-2023 helps you

In particular, then, our investigation gives you the following knowledge:
  • Revenue to 2023 for the world market - discover that industry's overall sales potential
  • Revenues to 2023 for world-level submarkets - investigate the potential of its components, finding the most promising places for investments and revenues
  • Revenues to 2023 for top products - find sales outlooks for top brands, seeing how they can compete and succeed
  • Forecasts to 2023 for national markets in North America, Europe, and Asia - discover the best countries for revenues and potential growth
  • Assessments of prominent companies - hear about developers and manufacturers' activities, results, and outlooks
  • Review of R&D - explore progress in research and development, finding technological and medical possibilities for that neurological disorder
  • Competition and opportunities - investigate what shapes that market's future, including ways to develop business
  • Analysis of what stimulates and restrains that industry and market - assess challenges and strengths, helping you compete and get advantages.
You gain information found nowhere else

That work gives independent analysis. You receive business intelligence found only in our report, seeing where prospects are most rewarding.

With our study you are less likely to fall behind in knowledge or miss opportunity. See there how you could benefit your research, analyses, and decisions. Also see how you can save time and get recognition for commercial insight.

Assess progress and potential now, seeing what you can gain.

Discover predictions for Alzheimer's-related products by ordering now

Our study lets you find data, trends, opportunities, and sales predictions for Alzheimer's medicine. Avoid missing out - please order our new report now.
1. EXECUTIVE SUMMARY

1.1 Overview of Findings
1.2 Structure of the Report
1.3 Research and Analysis Methods

2. ALZHEIMER'S DISEASE: AN INTRODUCTION

2.1 Neurodegenerative Diseases
  2.1.1 What is Alzheimer's Disease?
  2.1.2 What Causes Alzheimer's Disease?
    2.1.2.1 Alzheimer's Disease: Type 3 Diabetes?
  2.1.3 Management of Alzheimer's Disease
  2.1.4 The Socio-Economic Impact of Alzheimer's Disease
  2.1.5 Diagnosis of Alzheimer's Disease

3. ALZHEIMER'S DISEASE THERAPEUTICS AND DIAGNOSTICS MARKET, 2013-2023

3.1 Alzheimer's Disease Therapeutics and Diagnostics Market, 2012
3.2 Alzheimer's Disease Therapeutics and Diagnostics Market Forecast, 2012-2017
  3.2.1 The Market Has Been Left Exposed to Intensified Generic Competition
3.3 Alzheimer's Disease Therapeutics and Diagnostics Market Forecast, 2017-2023
  3.3.1 Healthcare Costs for Alzheimer's Disease Will Surpass All Other Medical Expenses
  3.3.2 The Current Drugs and Diagnostics Pipeline Is Strong
  3.3.3 New Diagnostics and Drugs Regulatory Guidelines Will Lower the Barriers to Entry
3.4 Drivers and Restraints

4. THE ALZHEIMER'S DISEASE DRUGS MARKET, 2013-2023

4.1 Current Approaches and Unmet Needs in the Treatment of Alzheimer's Disease
4.2 The Alzheimer's Disease Drugs Market, 2012
4.3 The Alzheimer's Disease Drugs Market Forecast, 2012-2017
4.4 The Alzheimer's Disease Drugs Market Forecast, 2017-2023
  4.4.1 Novel Drugs Will Dramatically Alter the AD Drugs Market to 2023
  4.4.2 A Global Aging Population Will Increase Disease Prevalence Over the Forecast Period
4.5 Namenda
  4.5.1 Namenda Sales Forecast 2013-2023
4.6 Aricept
  4.6.1 Aricept Sales Forecast, 2013-2023
4.7 Exelon
  4.7.1 Exelon Sales Forecast, 2013-2023
4.8 Alzheimer's Disease Drugs Pipeline, 2013
  4.8.1 Recent High-Profile Failures of Drugs in Development
    4.8.1.1 Gammagard
    4.8.1.2 Bapineuzumab
    4.8.1.3 Solanezumab
    4.8.1.4 Dimebon
    4.8.1.5 Avagacestat
  4.8.2 FDA to Relax Rules for the Approval of Alzheimer's Drugs
  4.8.3 Will Novel Drug Development Strategies Prove Successful?
  4.8.4 Promising Therapies in the Alzheimer's Disease Pipeline, 2013
    4.8.4.1 Gantenerumab (Roche)
    4.8.4.2 TTP488 (TransTech Pharma)
    4.8.4.3 SB-742457 (GlaxoSmithKline)
    4.8.4.4 CERE-110 (Ceregene)
    4.8.4.5 LMTX, TRx0237 (TauRx)
    4.8.4.6 EVP-6124 (EnVivo Pharmaceuticals)
    4.8.4.7 AD02 (Affiris)
    4.8.4.8 Deep Brain Stimulation (Functional Neuromodulation)
4.9 Leading Companies in the Alzheimer's Disease Drugs Market, 2012
  4.9.1 Pfizer, Inc.
    4.9.1.1 Sales and Recent Performance Analysis, 2012
    4.9.1.2 Pfizer: Aricept
    4.9.1.3 Pfizer: R&D Capabilities and Alzheimer's Disease Drug Candidates
    4.9.1.4 Recent Discontinued Alzheimer's Disease Projects
  4.9.2 Eisai Co., Ltd
    4.9.2.1 Sales and Recent Performance Analysis, 2012
    4.9.2.2 Eisai: Aricept
    4.9.2.3 Alzheimer's Disease Drug Pipeline
    4.9.2.4 Partnership with GE Healthcare for Diagnostic Development
  4.9.3 Forest Laboratories
    4.9.3.1 Sales and Recent Performance Analysis, 2012
    4.9.3.2 Forest: Namenda
  4.9.4 Lundbeck A/S
    4.9.4.1 Sales and Recent Performance Analysis, 2012
    4.9.4.2 Ebixa
    4.9.4.3 Alzheimer's Disease Drug Pipeline
  4.9.5 Novartis AG
    4.9.5.1 Sales and Recent Performance Analysis, 2012
    4.9.5.2 Novartis: Exelon
    4.9.5.3 eHealth Programme: Delivering Innovation
    4.9.5.4 Alzheimer's Disease Drug Pipeline
  4.9.6 TauRx
    4.9.6.1 Partnership with Bayer Schering Pharma AG
  4.9.7 AC Immune
    4.9.7.1 Groundbreaking $100m Trial for Alzheimer's Therapy
    4.9.7.2 AC Immune Halts Development of AC-91

5. THE ALZHEIMER'S DISEASE DIAGNOSTICS MARKET, 2013-2023

5.1 There is Still a Strong Market Need for Effective Diagnosis
5.2 The Alzheimer's Disease Diagnostics Market, 2012
5.3 New Criteria and Guidelines to Diagnose Alzheimer's Disease
5.4 Biomarkers for Alzheimer's Disease
  5.4.1 Leading Companies Pursuing Novel Biomarker Development Strategies
5.5 Alzheimer's Disease: Advances in Diagnostic Imaging Technologies
  5.5.1 Structural Imaging
  5.5.2 Functional Imaging
  5.5.3 Molecular Imaging Technologies
    5.5.3.1 Pittsburgh Compound B (PIB)
    5.5.3.2 18F Flutemetamol
    5.5.3.3 Florbetapir F18 (18F-AV-45)
    5.5.3.4 Florbetaben (Bay 94-9172)
    5.5.3.5 Other Alzheimer's Radiotracers in Development
5.6 Alzheimer's Disease Diagnostics Market Forecast, 2012-2017
5.7 Alzheimer's Disease Diagnostics Market Forecast, 2017-2022
5.8 Leading Companies in The Alzheimer's Disease Diagnostics Market, 2013
  5.8.1 Eli Lilly
    5.8.1.1Recent Performance and Sales Analysis, 2012
    5.8.1.2 Alzheimer's Disease Research Efforts
      5.8.1.2.1 Solanezumab
      5.8.1.2.2 Amyvid
      5.8.1.2.3 Amyvid Receives Marketing Authorization from the European Commission
      5.8.1.2.4 Eli Lilly Acquires Novel Tau Tangle Diagnostic Programme
  5.8.2 DiaGenic
    5.8.2.1 Collaborative Agreement with Pfizer
  5.8.3 Amarantus BioScience Holdings, Inc.
    5.8.3.1 LymPro
    5.8.3.2 Intellectual Property Acquisitions
  5.8.4 Piramal Enterprises
    5.8.4.1 Piramal Imaging SA
    5.8.4.2 Regulatory Acceptance for Review of Florbetaben
    5.8.4.3 Manufacturing and Distribution Agreements
  5.8.5 GE Healthcare
    5.8.5.1 GE's Commitment to Imaging Research in the Alzheimer's Field
    5.8.5.2 Regulatory Acceptance for Review of Flutemetamol
    5.8.5.3 Licensing Agreements for Flutemetamol

6. THE LEADING NATIONAL MARKETS, 2013-2023

6.1 Regional Breakdown of the Global Alzheimer's Disease Therapeutics and Diagnostics Market, 2012
  6.1.1 The US and Europe Represent More Than 70% of the Total Market
6.2 The Global Alzheimer's Disease Therapeutics and Diagnostics Market: Regional Forecast, 2013-2023
6.3 Changing Market Shares of Leading National Markets, 2013-2023
6.4 The US Alzheimer's Disease Therapeutics and Diagnostics Market, 2012-2023
  6.4.1 One in Eight Over the Age of 65 has AD in the US
  6.4.2 The US Will Remain the Largest Market Over the Forecast Period
6.5 The European Alzheimer's Disease Therapeutics and Diagnostics Market, 2012-2023
  6.5.1 Germany 2012-2023: The Largest European Market
  6.5.2 The French Market, 2012-2023: Highest Healthcare Spender in Europe
  6.5.3 The UK Market, 2012-2023: Spending Restrictions
  6.5.4 The Spanish Market, 2012-2023: Cost Containment Measures Will Continue to Affect the Market
  6.5.5 The Italian Market, 2012-2023
6.6 The Japanese Market, 2012-2023: The Second Largest National Market in 2012
6.7 The Chinese Market, 2012-2023: One of the Fastest Growing Markets
6.8 The Indian Market, 2012-2023: Improvements in Regulations Will Boost the Market to 2023

7. QUALITATIVE ANALYSIS OF THE ALZHEIMER'S DISEASE THERAPEUTICS AND DIAGNOSTICS MARKET, 2013

7.1 SWOT Analysis
7.2 Strengths
  7.2.1 Alzheimer's Disease is a High Profile Disease
  7.2.2 Expanding Patient Population
  7.2.3 Strong R&D Pipeline in Both Sectors of the Market
7.3 Weaknesses
  7.3.1 Current Drugs Only Treat the Symptoms of Alzheimer's Disease
  7.3.2 Recent Failures of Promising Drug Candidates in Clinical Trials
  7.3.3 Poor Macroeconomic Conditions in Key Regions of the Market
7.4 Opportunities
  7.4.1 Regulators Seeking Improved Standards of Alzheimer's Disease Drug Development
  7.4.2 Neurodegenerative Diseases Have Strong R&D
  7.4.3 Emerging Markets Will Help Drive the Market
  7.4.4 Advances in Diagnostic Technologies Will Improve Drug Market Penetration
7.5 Threats
  7.5.1 Patent Expiries Will Lead to Further Generic Competition
  7.5.2 New AD Therapies Face Political, Commercial and Social Pressures
7.6 Porter's Five Force Analysis
  7.6.1 Rivalry Among Competitors
  7.6.2 Threat of New Entrants
  7.6.3 Power of Suppliers
  7.6.4 Bargaining Power of Suppliers
  7.6.5 Threat of Substitutes

8. RESEARCH INTERVIEW

8.1 Interview with Professor J№rgen GЎtz
  8.1.1 The Obstacles for Developing a Cure for Alzheimer's Disease
  8.1.2 The Time Frame for Developing a Cure for Alzheimer's Disease
  8.1.3 Potential Alzheimer's Disease Treatments
  8.1.4 The Market Potential for a Cure for Alzheimer's Disease

9. CONCLUSIONS

9.1 Disease-Modifying Drugs and Novel Diagnostic Technologies Will Transform the Market
9.2 Demographics Will Help Drive the Market Over the Forecast Period
9.3 Medicines and Diagnostic Tests for Alzheimer's Disease Hold Great Potential from 2013 to 2023

LIST OF TABLES

Table 2.1 Leading Sectors in the Neurodegenerative Disease Market, 2013
Table 2.2 Imaging Technologies Used in Alzheimer's Research, 2013
Table 3.1 The Global Alzheimer's Disease Therapeutics and Diagnostics Market: Revenues ($bn) and Market Shares (%) by Sector, 2012
Table 3.2 Alzheimer's Disease Therapeutics and Diagnostics Market Forecasts: Revenues ($bn), AGR (%), CAGR (%), 2012-2017
Table 3.3 Alzheimer's Disease Therapeutics and Diagnostics Market Forecasts: Revenues ($bn), AGR (%), CAGR (%), 2017-2023
Table 3.4 The Alzheimer's Disease Therapeutics and Diagnostics Market: Drivers and Restraints, 2013
Table 4.1 The Alzheimer's Disease Drugs Market: Revenues ($bn) and Market Shares (%) by Leading Drugs, 2012
Table 4.2 Alzheimer's Disease Drugs Market Forecast: Revenues ($bn), AGR (%), CAGR (%), 2012-2017
Table 4.3 Alzheimer's Disease Drugs Market Forecast: Revenues ($bn), AGR (%), CAGR (%), 2017-2023
Table 4.4 Selected List of Alzheimer's Disease Drugs in the Pipeline, 2013
Table 4.5 Pfizer: Revenues ($bn) and Revenue Shares (%) by Sector, 2012
Table 4.6 Pfizer: Aricept Revenue Forecast ($bn), AGR (%), CAGR (%), 2012-2023
Table 4.7 Pfizer: Alzheimer's Disease Drug Pipeline, 2013
Table 4.8 Eisai: Aricept Revenue Forecast ($bn), AGR (%), CAGR (%), 2012-2023
Table 4.9 Forest: Namenda's Historical Revenues ($bn), AGR (%) and Percentage of Net Sales (%), 2009-2013
Table 4.10 Forest: Namenda Sales Forecast ($bn), AGR (%), CAGR (%), 2012-2023
Table 4.11 Lundbeck: Revenues ($bn) and Revenue Shares (%) by Region, 2012
Table 4.12 Ebixa: Revenues ($bn) and Revenue Shares (%) by Region, 2012
Table 4.13 Ebixa: Sales Forecast ($bn), AGR (%), CAGR (%), 2012-2023
Table 4.14 Novartis: Revenue ($bn) and Revenue Shares (%) by Segment, 2012
Table 5.1 The Alzheimer's Disease Diagnostics Market: Revenues ($bn) and Market Shares (%) by Segment, 2012
Table 5.2 The Alzheimer's Disease Diagnostics Market Forecast: Revenues ($bn), AGR (%), CAGR (%) by Sector, 2012-2017
Table 5.3 The Alzheimer's Disease Diagnostics Market Forecast: Revenues ($bn), AGR (%), CAGR (%), by Sector, 2017-2023
Table 5.4 Diagenic: Diagnostics Pipeline, 2013
Table 6.1 The Alzheimer's Disease Therapeutics and Diagnostics Market: Revenues ($bn) and Market Shares (%) by Region, 2012
Table 6.2 The Alzheimer's Disease Therapeutics and Diagnostics Market Forecast: Revenues ($bn), AGR (%), CAGR (%), by Region, 2012-2017
Table 6.3 The Alzheimer's Disease Therapeutics and Diagnostics Market Forecast: Revenues ($bn), AGR (%), CAGR (%), by Region, 2017-2023
Table 6.4 Regional Alzheimer's Disease Therapeutics and Diagnostics Market Forecast: CAGR (%), 2012-2017, 2017-2023 and 2012-2023
Table 6.5 Market Shares (%) of the Leading Regional Alzheimer's Disease Therapeutics and Diagnostics Markets, 2012, 2017 and 2023
Table 6.6 The US Alzheimer's Disease Therapeutics and Diagnostics Market Forecast Summary: Size ($bn), Rank, Share (%), CAGR (%), 2012-2023
Table 6.7 The European Alzheimer's Therapeutics and Diagnostics Market: Revenues ($bn), European Market Share (%) and Global Market Share (%) by Leading Countries, 2012
Table 6.8 The European Alzheimer's Disease Therapeutics and Diagnostics Market Forecast: Revenues ($bn), AGR (%), CAGR (%) by Leading Country, 2012-2017
Table 6.9 The European Alzheimer's Disease Therapeutics and Diagnostics Market Forecast: Revenues ($bn), AGR (%), CAGR (%) by Leading Country, 2017-2023
Table 6.10 The Japanese Alzheimer's Disease Therapeutics and Diagnostics Market Forecast Summary: Size ($bn), Rank, Share (%), CAGR (%), 2012-2023
Table 6.11 The Chinese Alzheimer's Disease Therapeutics and Diagnostics Market Forecast Summary: Size ($bn), Rank, Share (%), CAGR (%), 2012-2023
Table 6.12 The Indian Alzheimer's Disease Therapeutics and Diagnostics Market Forecast Summary: Size ($bn), Rank, Share (%), CAGR (%), 2012-2023
Table 6.13 India: Population Forecast by Age Group (%), 2010, 2015 and 2020
Table 7.1 SWOT Analysis of the Alzheimer's Disease Therapeutics and Diagnostics Market, 2013
Table 9.1 The Global Alzheimer's Disease Therapeutics and Diagnostics Market: Revenues ($bn) by Region, in 2012, 2017 and 2023
Table 9.2 The Global Alzheimer's Disease Therapeutics and Diagnostics Market ($bn) by Sector, 2012, 2017 and 2023

Eisai separates reporting segments for its pharmaceutical business by geographical region.Eisai reported that sales for Aricept declined 49.4% year on year in fiscal 2011, following the expiration of the composition of matter patent in the US. Sales of Aricept in the East Asia segment were reported to have advanced 2.7%. In Japan, Aricept sales increased 2.6%, reaching $1.3bn in 2011. In December 2011, Eisai submitted an application seeking approval of a new, dry syrup formulation in Japan. A phase III study of the higher dose Aricept 23mg tablet formulation is also ongoing in Japan. In the US, Aricept sales fell 92.6% (91.9% on a local currency basis) in 2011. In Europe, sales of Aricept decreased 17.4%, to $0.2bn, due to patent expiration. In the company’s New Markets and ASEAN segment, Aricept sales were reported to have decreased by 4.6%, to $20.7m in 2011.

According to Eisai’s fiscal 2011 annual report, Aricept remains the leading brand in India in its category, despite the entry of many competitors since the company launched it locally in 2005. In this highly competitive market, Eisai sells the drug in India at a price about 90.0% less than it sales price in Japan. In addition Eisai is promoting initiatives to raise awareness of dementia of the Alzheimer’s type in India. In an effort to ensure that patients in India receive appropriate treatment, Eisai distributes free pamphlets with information on caring for dementia to patients and their families, and supports the establishment of outpatient memory clinics while providing training and education for the medical staff. 

The latest financial results from Eisai show Aricept achieved revenues of approximately $0.7bn in the East Asia segment, in the third quarter of fiscal 2012. This represents a decrease of approximately 42.3%, over the same quarter, in the previous fiscal year. Aricept’s sales in Japan reached $0.7bn, a decline of approximately 39.6% over the previous fiscal year. The decline of sales in Japan was due to the impact of the NHI drug price revisions and intensified market competition. Moreover, Eisai terminated the co-promotion of Aricept with Pfizer Japan Inc. and, as a result, the company assumed sole promotion on January 1, 2013. Aricept achieved sales of $0.5bn in the Americas business segment and $27.8m in the EMEA segment, during the company’s third quarter of fiscal year 2012.

Eisai revised its full year sales forecast for Aricept in light of the most recent levels of sales in Japan. Eisai is expecting full year global net sales for Aricept at $1.2bn, which compared to fiscal 2011, would represent a decline of approximately 37.2%. The company had previously forecast Aricept to achieve approximately $1.4bn in sales for the full fiscal year. Table 4.8 and Figure 4.15show our forecast for Eisai’s Aricept sales over the next decade. We have used Eisai’s 2012 financial guidance to estimate Aricept’s revenues for fiscal year 2012.



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