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Advanced Non-squamous and squamous NSCLC - Pipeline Insight, 2021

February 2021 | 60 pages | ID: A7014E2F14EDEN
DelveInsight

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DelveInsight’s, “Advanced Non-Squamous & Squamous NSCLC – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Advanced Non-Squamous & Squamous NSCLC pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Advanced Non-Squamous & Squamous NSCLC Understanding

Advanced Non-Squamous & Squamous NSCLC: Overview

Lung cancer is one of the most common types of cancer across the globe and among the leading causes of cancer-related deaths. Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers and is further classified into squamous NSCLC and non-squamous NSCLC (includes large cell histologies and adenocarcinoma). Squamous NSCLC accounts for about 30% of NSCLC cases while non-squamous NSCLC is more commonly observed. Squamous NSCLC is an aggressive form of lung cancer for which there is significant dearth of well-tolerated and effective treatments.

“Advanced Non-Squamous & Squamous NSCLC - Pipeline Insight, 2021” report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Advanced Non-Squamous & Squamous NSCLC pipeline landscape is provided which includes the disease overview and Advanced Non-Squamous & Squamous NSCLC treatment guidelines. The assessment part of the report embraces, in depth Advanced Non-Squamous & Squamous NSCLC commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Advanced Non-Squamous & Squamous NSCLC collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Advanced Non-Squamous & Squamous NSCLC R&D. The therapies under development are focused on novel approaches to treat/improve Advanced Non-Squamous & Squamous NSCLC.

Advanced Non-Squamous & Squamous NSCLC Emerging Drugs Chapters

This segment of the Advanced Non-Squamous & Squamous NSCLC report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Advanced Non-Squamous & Squamous NSCLC Emerging Drugs

Tiragolumab (RG6058): F. Hoffmann-La Roche Ltd

Roche’s drug candidate Tiragolumab is in the phase III stage of the drug development process. It is being developed for the first line NSCLC where the drug is being tested in combination with Tecentriq. Tiragolumab is a fully human monomclonal antibody which is designed to bind with TIGIT and inhibit the interaction between poliovirus receptor and TIGIT.

SAR408701: Sanofi

Sanofi’s drug molecule SAR408701 is in the phase II stage of the drug development process. It is a monoclonal antibody which works as a tubulin inhibitor and CEACAM5 targeting antibody. It is being developed as a combination therapy.

Further product details are provided in the report……..

Advanced Non-Squamous & Squamous NSCLC: Therapeutic Assessment

This segment of the report provides insights about the different Advanced Non-Squamous & Squamous NSCLC drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Advanced Non-Squamous & Squamous NSCLC

There are approx. 4+ key companies which are developing the therapies for Advanced Non-Squamous & Squamous NSCLC. The companies which have their Advanced Non-Squamous & Squamous NSCLC drug candidates in the most advanced stage, i.e. phase II include, Sanofi.

Phases

DelveInsight’s report covers around 10+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
Route of Administration

Advanced Non-Squamous & Squamous NSCLC pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Subcutaneous
  • Intravitreal
  • Intramuscular
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Advanced Non-Squamous & Squamous NSCLC: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Advanced Non-Squamous & Squamous NSCLC therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Advanced Non-Squamous & Squamous NSCLC drugs.

Advanced Non-Squamous & Squamous NSCLC Report Insights
  • Advanced Non-Squamous & Squamous NSCLC Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Advanced Non-Squamous & Squamous NSCLC Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Advanced Non-Squamous & Squamous NSCLC drugs?
  • How many Advanced Non-Squamous & Squamous NSCLC drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Advanced Non-Squamous & Squamous NSCLC?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Advanced Non-Squamous & Squamous NSCLC therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Advanced Non-Squamous & Squamous NSCLC and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • F. Hoffmann-La Roche Ltd
  • Sanofi
Key Products
  • Tiragolumab
  • SAR408701?
Introduction
Executive Summary
Advanced Non-Squamous & Squamous NSCLC: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Advanced Non-Squamous & Squamous NSCLC – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  Advanced Non-Squamous & Squamous NSCLC companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Advanced Non-Squamous & Squamous NSCLC Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
Tiragolumab: F. Hoffmann-La Roche Ltd
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
  Comparative Analysis
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  Comparative Analysis
Advanced Non-Squamous & Squamous NSCLC Key Companies
Advanced Non-Squamous & Squamous NSCLC Key Products
Advanced Non-Squamous & Squamous NSCLC- Unmet Needs
Advanced Non-Squamous & Squamous NSCLC- Market Drivers and Barriers
Advanced Non-Squamous & Squamous NSCLC- Future Perspectives and Conclusion
Advanced Non-Squamous & Squamous NSCLC Analyst Views
Advanced Non-Squamous & Squamous NSCLC Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for Advanced Non-Squamous & Squamous NSCLC
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

LIST OF FIGURES

Figure 1 Total Products for Advanced Non-Squamous & Squamous NSCLC
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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