2015 Nucleic Acid Testing Market: Strategic Assessments of Leading Suppliers

July 2015 | 549 pages | ID: 2D346709044EN
Venture Planning Group

Abstracts

This 549-page report presents an overview of the clinical significance and market needs for major current and emerging NAT assays, as well as extensive listings of companies developing and marketing innovative technologies and products. This report also presents strategic assessments of current and emerging suppliers of nucleic acid testing products, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies. Contains 549 pages and 22 tables

Contents

MICROBIOLOGY/INFECTIOUS DISEASES

a. Overview
b. Major Infectious Diseases
  AIDS
    Structure and Composition
    Classification
    AIDS Origins
    Animal Lentivirus Systems
    Virus Receptors
    HIV Infections in Humans
      Pathogenesis and Pathology
    CD4T Lymphocytes and Memory Cells
    Monocytes and Macrophages
    Lymphoid Organs
    Neural Cells
    Viral Coinfections
      Clinical Findings
    Plasma Viral Load
    Pediatric AIDS
      Neurologic Disease
      Opportunistic Infections
      Cancer
    Immunity
      Virus Isolation
      Serology
      Viral Nucleic Acid/Antigen Detection
    Epidemiology
      Worldwide Spread of AIDS
      United States
      Routes of Transmission
    DNA Probes
      Overview
      Quantitative PCR
      In Situ PCR
      Needed Improvements
    Viral Load/Drug Resistance Testing
    Genotype and Phenotype Testing
    Blood Banking Considerations
  Adenovirus
      Background
      Diagnostic Tests
      Vaccines and Drugs
    Adeno-Associated Viruses (AAV)
  Anthrax/Bacillus Anthracis
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Babesiosis
      Background
  BEA and Other Bartonella Diseases
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Chagas Disease
      Background
  Campylobacter
      Background
      Diagnostic Tests
      Culture Identification
      Vaccines and Drugs
  Chlamydia
      Background
        Chlamydia psittaci
        Chlmaydia pneumoniae
        Chlamydia trachomatis
      Diagnostic Tests
      Vaccines and Drugs
  Creutzfeldt-Jakob’s Disease
      Background
    Blood Transmission
      Diagnostic Tests
      Major Commercial and Academic Players
        Bayer
        Disease Sciences/Bio Tec Global
        Imperial College School of Medicine
        Ortho-Clinical Diagnostics
        Pall
        ProMetic Life Sciences
        Proteome Sciences/Idexx
        Q-One Biotech
        Serono
        U.S. Agricultural Research Service
    Drugs
    Vaccines
  Cytomegalovirus
      Background
        Chorioretinitis
        Gastrointestinal
        Central Nervous System Disease
      Diagnostic Tests
      Vaccines and Drugs
  Ebola Virus
      Background
        Epidemiology
        Clinical Syndromes
      Diagnostic Tests
      Vaccines and Drugs
  EchoVirus
      Background
        Acute Aseptic Meningitisis
        Encephalitis
        Exanthems
        Respiratory Disease
        Myopericarditis
        Neonatal Infections
      Diagnostic Tests
      Vaccines and Drugs
  Encephalitis
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Enteroviruses
      Background
      Diagnostic Tests
        Viral Isolation and Identification
        Antibody Tests
      Vaccines and Drugs
  Epstein-Barr Virus
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Gonorrhea
    Background
    Diagnostic Tests
    Vaccines and Drugs
  Hepatitis
    Hepatitis A
    Hepatitis B
      Structure and Composition
      Replication
    Hepatitis C
    Hepatitis D (Delta)
    Hepatitis E
    Hepatitis G
    Hepatitis Infections Pathology
    Clinical Findings
    Laboratory Tests
    Hepatitis A
    Hepatitis B
    Hepatitis C
    Hepatitis D
    Hepatitis E
    Virus-Host Immune Reactions
    Epidemiology
    Hepatitis A
    Hepatitis B
    Hepatitis C
    Hepatitis D (Delta)
      Vaccines and Drugs
  Herpes Simplex Virus
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Legionella
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Lyme Disease
      Background
        Clinical Description
        Clinical Case Definition
        Laboratory Criteria for Diagnosis
        Case Classification
      Diagnostic Tests
      Vaccines and Drugs
  Malaria
  Mycoplasma
      Background
        Ureaplasma Urealyticum & Mycoplasma Hominis
      Diagnostic Tests
      Vaccines and Drugs
  Papillomaviruses/HPV
      Background
        HPV in Cancer
        Cervical Neoplasm
      Diagnostic Tests
      Vaccines and Drugs
        Prevention
  Parvovirus B19
      Background
        Microbiology
        Epidemiology
        Clinical Syndromes
        Erythema Infectiosum (Slapped Cheek)
        Adult Polyarthropathy
        Transient Aplastic Crisis
        Transient Pancytopenia
        Red Cell Aplasia in Immunocompromised
        Perinatal Infections
    Diagnostic Test
      Vaccines and Drugs
  Pneumonia
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Polyomaviruses
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Salmonellosis
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Shigellosis
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Streptococci
      Background
      Diagnostic Tests
      Vaccines and Drugs
        Group A Streptococci
        Group B Streptococci
  Toxoplasmosis
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Tuberculosis
      Background
      Diagnostic Tests
        Microscopic Characteristics
        Cultural Characteristics
        Skin Tests
        MDRTB
      Vaccines and Drugs
  West Nile Virus
      Background
        Clinical Syndromes
      Diagnostic Tests
      Vaccines and Drugs
  Yersinia
      Background
      Diagnostic Tests
      Vaccines and Drugs
  Antibiotic Susceptibility

CANCER TESTING

a. Overview
b. Major Cancer Types
  Prostate
  Lung
  Colon and Rectum
  Breast
  Skin
  Uterine
  Leukemia
  Oral
c. Oncogenes
  Abl/abl-bcr
  AIB1
  BCL-2
  BRCA1
  CD44
  C-fos
  C-myb
  C-myc
  CYP17
  Erb-B
  HPC1
  N-myc
  P40
  P51
  P53
  PIK3CA
  PTI-1
  Ras
  Reg
  Sis
  Src

GENETIC DISEASES

a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
  Achondroplasia
  Autosomal Dominant Polycystic Kidney Disease
  Cancer
  Cosmetogenomics
  Cystic Fibrosis
  Down's Syndrome
  Duchenne and Becker Muscular Dystrophy
  Factor V (Leiden)
  Factor IX Deficiency
  Fragile X Syndrome
  Heart Disease
  Hemochomatosis
  Hemophilia
  Huntington's Disease
  Maternal-Fetal Incompatibility
  Multiple Endocrine Neoplasia
  Phenylketonuria (PKU)
  Polycystic Kidney Disease (PKD)
  Prenatal Screening
  Retinitis Pigmentosa
  Retinoblastoma
  Sickle Cell Anemia
  Spinal Muscular Atrophy
  Vitamin B12 Metabolism
i. Social Issues and Concerns Forensic Testing
  a. Overview
  b. Multilocus and Single Locus Probes
    Multilocus Probes
    Single Locus Probes
    PCR and RFLP
  c. The FBI
  d. DNA Profile Data Banks
    U.S.A.
    U.K.
  e. Judicial Implementation
  f. Major Crime Categories
  g. Factors Contributing to the DNA Probe Market Expansion
    Technology Availability
    Use of Hair as Evidence
  h.

WILDLIFE FORENSICS PATERNITY TESTING/HLA TYPING

OTHER APPLICATIONS

a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other

COMPETITIVE PROFILES

Abbott
Affymetrix
Agilent
Applied Gene Technologies
Arca
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
Bio-Rad
Biotest
Caliper
Cepheid
Decode
Diadexus
Eiken
Enzo
Exact Sciences
Fujirebio
Gen-Probe
Hologic
Illumina
Innogenetics/Solvay
Kreatech
Li-Cor Biosciences
Life Technologies
Monogram Biosciences
Myriad Genetics
Nanogen/Elitech
Novartis
Orchid CellMark
Ortho-Clinical Diagnostics
Proteome Sciences
Qiagen
Roche
Scienion
Sequenom
Shimadzu
Siemens
Sierra Molecular
Takara Bio
Tecan Group

List Of Tables

LIST OF TABLES

Major Companies Developing or Marketing AIDS Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Herpes Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Legionella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Papilloma Virus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Shigella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic And Other Direct Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular Diagnostic Test For Genetic Diseases