Emerging Transfusion Diagnostic Tests and Companies Developing Innovative Technologies and Products

February 2012 | 186 pages | ID: TFF883AA26DEN
Venture Planning Group

Abstracts

This 186-page report presents a comprehensive analysis of the clinical significance and market needs for major blood typing, grouping, and infectious disease screening assays, including NAT tests, as well as extensive listings of companies developing or marketing new transfusion testing technologies and products.

Contains 186 pages and 7 tables

Contents

1. BLOOD TYPING AND GROUPING TESTS

a. ABO
b. Antibody Panels
c. Antibody Screening
d. Antigen Typing
e. Antiglobulin Test
f. Crossmatch
g. HLA Typing
h. Rh
i. Other Blood Groups

2. INFECTIOUS DISEASE SCREENING TESTS

a. AIDS
  Structure and Composition
  Classification
  HIV-2 Infection
  Origin of AIDS
  Animal Lentivirus Systems
  Virus Receptors
  HIV Infections in Humans
    Pathogenesis & Pathology
    Overview of Course of HIV Infection
  CD4T Lymphocytes and Memory Cells
   Monocytes and Macrophages
   Lymphoid Organs
   Neural Cells
   Viral Coinfections
    Clinical Findings
  Plasma Viral Load
   Pediactric AIDS
    Neurologic Disease
    Opportunistic Infections
    Protozoa
    Fungi
    Bacteria
    Viruses
    Cancer
    Immunity
    Laboratory Diagnosis
      Virus Isolation
      Serology
      Detection of Viral Nucleic Acid or Antigens
     Epidemiology
      Worldwide Spread of AIDS
      United States
      Routes of Transmission
     Prevention, Treatment, And Control
      Antiviral Drugs
      Vaccines Against HIV
   Transmission of HIV in Blood Products
   HIV Transmission in Transplant and Artificial Insemination Recipients
   Diagnostic Tests
    Enzyme Immunoassay Interpretation
    Specificity, Sensitivity, and Predictive Value of Enzyme Immunoassay
  Competition Assays
   Western Blot Technique
   Immuno-Fluorescence Assay (IFA)
   Radioimmunoprecipitation
   HIV-1/HIV-2 Combination Testing
  Methods of HIV-Antigen Detection
   Antigen Assays and Blood Screening
   Urine Tests
   DNA Probes
     Overview
     Quantitative Polymerase Chain Reaction
     In Situ PCR
     Needed Improvements
   Viral Load/Drug Resistance Testing
   Genotype and Phenotype Testing
   Blood Banking Considerations
b. Hepatitis
   Hepatitis A
   Hepatitis B
    Structure and Composition
    Replication of Hepatitis B Virus
     Hepatitis C
     Hepatitis D (Delta Hepatitis)
     Hepatitis E
     Hepatitis G
    Hepatitis Virus Infections In Humans
      Pathology
     Clinical Findings
     Laboratory Features
      Hepatitis A
      Hepatitis B
      Hepatitis C
      Hepatitis D
      Hepatitis E
     Virus-Host Immune Reactions
     Epidemiology
      Hepatitis A
      Hepatitis B
      Hepatitis C
      Hepatitis D (Delta Agent)
     Vaccines and Drugs
c. Cytomegalovirus
   Background
   Chorioretinitis
   Gastrointestinal
  Central Nervous System Disease
   Diagnostic Tests
   Vaccines and Drugs
d. Syphilis
   Background
   Diagnostic Tests
   Vaccines and Drugs
e. West Nile Virus
   Background
  Clinical Syndromes
   Diagnostic Tests
   Vaccines and Drugs
f. Parvovirus B19
   Microbiology
   Epidemiology
   Clinical Syndromes
  Erythema Infectiosum Slapped (cheek)
  Adult Polyarthropathy
  Transient Aplastic Crisis
  Transient Pancytopenia
    Red Cell Aplasia in the Immunocompromised
  Perinatal Infections
   Diagnosis
   Treatment
g. Creutzfeldt-Jakob’s Disease
   Background
   Transmission
   Diagnostic Tests
   Major Commercial and Academic Players
    Bayer
    Disease Sciences/BioTec Global
    Imperial College School of Medicine
    Ortho-Clinical Diagnostics
    Pall
    ProMetic Life Sciences
    Proteome Sciences/Idexx
    Q-One Biotech
    Serono
    U.S. Agricultural Research Service
  Drugs
   Vaccines
h. Malaria
i. Chagas Disease
j. Babesiosis

3. PATHOGEN REDUCTION

4. LEUKOCYTE REDUCTION

Background
Methods

List Of Tables

LIST OF TABLES

Major Companies Developing or Marketing Blood Typing and Grouping Tests
Major Companies Developing or Marketing HLA Typing Tests
Major Companies Developing or Marketing AIDS Tests
Major Companies Developing or Marketing Hepatitis Tests
Major Companies Developing or Marketing CMV Tests
Major Companies Developing or Marketing Syphilis Tests