TOP 10 Drug Discovery Technologies – Strategic Analysis and Global Forecasts

Date: November 22, 2010
Pages: 311
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Report type: Strategic Report
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TOP 10 Drug Discovery Technologies – Strategic Analysis and Global Forecasts
Top 10 drug discovery technologies – strategic analysis and global forecasts (2010 to 2015)

The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs, which is the most important aspect for the pharmaceutical companies. The applications of these technologies in the introduction of drugs for diverse diseases such as cancer, CVD, CNS disorders such as Parkinson’s and Alzheimer’s and other serious chronic diseases have created significant opportunities for the market growth in the future. The slow growth of the introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.

The global top 10 drug discovery technologies market is expected to be around $ 30.8 billion in 2010 and estimated to reach $ 54 billion mark in 2015, growing at a CAGR of 11.9 % from 2010-2015. The market for high throughput screening accounts for the largest share with approximately 33% of the entire market for top 10 drug discovery technologies. This huge market share is mainly due to the increasing applications of cell based assays and robotics in the parallel screening of compounds.

Scope of the report

This research report includes following drug discovery technologies:
  • High throughput screening (robotics and automation, cell based assays, miniaturization, high content screening and ultra high throughput screening)
  • Bioanalytical instruments (mass spectrometry, NMR, micro plate readers and chemotherapy instruments)
  • Pharmacogenomics
  • Combinatorial chemistry
  • Genomics (functional and structural genomics)
  • Biochips (DNA microarrays, lab on a chip, proteomics microarrays)
  • Bioinformatics
  • Proteomics (2DGE, two hybrid systems, isotope encoding and activity based assays)
  • RNAi (siRNA, miRNA, ddRNAi, short hairpin RNAs)
  • Nanotechnology (Atomic force microscopy, nano mass spectroscopy, dip pen nanolithography and other nanotechnologies)

Each section will provide market data, market drivers, trends and opportunities, top-selling products, key players, and competitive outlook. This report will also provide market tables for covering the sub-segments and micro-markets. In addition, the report also provides more than 20 company profiles covering all the sub-segments.

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  • We provide the longest market segmentation chain in this industry- not many reports provide market breakdown upto level 5.
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  • We conduct detailed market positioning, product positioning and competitive positioning. Entry strategies, gaps and opportunities are identified for all the stakeholders.
  • Comprehensive market analysis for the following sectors:

Pharmaceuticals, Medical Devices, Biotechnology, Semiconductor and Electronics, Energy and Power Supplies, Food and Beverages, Chemicals, Advanced Materials, Industrial Automation, and Telecom and IT. We also analyze retailers and super-retailers, technology providers, and research and development (R&D) companies.

Key questions answered
  • Which are the high-growth segments/cash cows and how is the market segmented in terms of applications and materials?
  • What are market estimates and forecasts; which markets are doing well and which are not?
  • Where are the gaps and opportunities; what is driving the market?
  • Which are the key playing fields? Which are the winning edge imperatives?
  • How is the competitive outlook; who are the main players in each of the segments; what are the key selling products; what are their strategic directives, operational strengths and product pipelines? Who is doing what?

Powerful Research and analysis

The analysts working with MarketsandMarkets come from renowned publishers and market research firms, globally, adding their expertise and domain understanding. We get the facts from over 22,000 news and information sources, a huge database of key industry participants and draw on our relationships with more than 900 market research companies across the world. We, at MarketsandMarkets, are inspired to help our clients grow by providing qualitative business insights with our huge market intelligence repository.
EXECUTIVE SUMMARY

Objective
Market scenario

1 INTRODUCTION

1.1 Key take-aways
1.2 Report description
1.3 Markets covered
1.4 Research methodology
1.5 Stakeholders

2 SUMMARY

3 MARKET OVERVIEW

3.1 Market segmentation
3.2 High throughput screening & bioanalytical instruments leading the market
3.3 Patent analysis

4 DRIVING FACTOR ANALYSIS

4.1 Drivers
  4.1.1 Contract research boosting technology adoption
  4.1.2 Collaborations between academia & pharmaceutical industry
  4.1.3 Increased necessity for ADME/toxicity technologies
4.2 Opportunities
  4.2.1 Offshoring scenario for drug discovery

5 HIGH THROUGHPUT SCREENING

5.1 Introduction
5.2 Market overview
5.3 Burning issues & winning imperatives
  5.3.1 Increasing participation from academic research
  5.3.2 High throughput screening set up: pharmaceutical vs academic
5.4 Ultra high throughput screening
5.5 Robotics & automation
5.6 Miniaturization
5.7 High content screening
  5.7.1 Opportunities
    5.7.1.1 GPCR drug discovery
5.8 Cell based assays

6 BIOANALYTICAL INSTRUMENTS

6.1 Introduction
6.2 Burning issues & trends
  6.2.1 Pharmaceutical industry a major end client
  6.2.2 Agilent penetration in bioanalytical instruments market
  6.2.3 Outsourcing scenario
6.3 Mass spectrometry
  6.3.1 Upcoming technology - Maldi-QMS
6.4 Microplate readers
6.5 Nuclear magnetic resonance
6.6 Chemotherapy instruments

7 PHARMACOGENOMICS

7.1 Introduction
7.2 Pharmacogenomics applications in drug development
7.3 Burning issues
  7.3.1 Commercial hurdles in drug development
    7.3.1.1 Cost issues in clinical development
    7.3.1.2 FDA approval
    7.3.1.3 Ethical issues
  7.3.2 Pharmacogenomics for drug reintroduction
  7.3.3 Pharmacogenomics applications in existing drugs
7.4 Key trends in the pharmacogenomics technology market
  7.4.1 Regulatory initiatives boosting adoption for pharmacogenomics technology
  7.4.2 Rise in pharmacogenomics consortia boost technology based research
  7.4.3 Increasing importance of databases
7.5 Future prospects for pharmacogenomics technology research
7.6 Pharmacogenomics products: pricing effects
  7.6.1 Case study: high priced herceptin
  7.6.2 Pharmacogenomics cost effectiveness
7.7 Pharmacogenomics technology: short & long term benefits
  7.7.1 Improvement in patient safety
  7.7.2 Increase in drug effectiveness
  7.7.3 Selection of medication for chronic diseases
  7.7.4 Better economic efficiency for the healthcare system
  7.7.5 Improved patient access to drugs

8 COMBINATORIAL CHEMISTRY

8.1 Introduction
8.2 Market drivers
  8.2.1 Technological advances boost adoption of combinatorial chemistry
  8.2.2 Process enhancement results in better compounds
  8.2.3 Collaborative approach
  8.2.4 Need for novel compounds acts as market opportunity
8.3 Stakeholders characteristics
8.4 Burning issues
8.5 Key trends and market boosters
  8.5.1 Increased recognition of combinatorial chemistry technology
  8.5.2 Faster drug discovery

9 GENOMICS

9.1 Introduction
9.2 Winning imperatives
  9.2.1 Reducing cost for whole genome sequencing
9.3 Functional genomics
9.4 Structural genomics

10 BIOCHIPS

10.1 Introduction
10.2 Burning issues
  10.2.1 Business trends
  10.2.2 Patent disputes
  10.2.3 Competition
10.3 Industry trends
  10.3.1 Next generation technology: microfluidics with CD-ROM
  10.3.2 Biochips in biomarker development
  10.3.3 Outsourcing the biochip technology
10.4 DNA microarrays
  10.4.1 Market drivers
    10.4.1.1 Increased utilization in complex diseases
    10.4.1.2 Sequence data proliferation
    10.4.1.3 Easy-access programs
10.5 Lab on a chip
  10.5.1. New technology & cost saving by lab on a chip boost the market
10.6 Proteomics microarrays
  10.6.1 Burning issues and trends
    10.6.1.1 Technical lags
    10.6.1.2 Human protein microarray for multiple protein analysis

11 BIOINFORMATICS

11.1 Introduction
11.2 Burning issues and trends
  11.2.1 Outsourcing
  11.2.2 Allocation of grants

12 PROTEOMICS

12.1 Introduction
12.2 Industry trends
  12.2.1 Funding for proteomics research
  12.2.2 Proteomics in anti cancer drug discovery
12.3 Two dimensional gel electrphoresis- 2DGE
12.4 Two-hybrid systems

13 RNAI

13.1 Technology overview
13.2 Winning imperatives
  13.2.1 Core competency acquisition
13.3 Opportunity in RNAi drug discovery
  13.3.1 RNAi based cholesterol drugs
  13.3.2 Cancer drugs
13.4 SiRNA
13.5 MiRNAS
13.6 Other RNAi technologies

14 NANOTECHNOLOGY

14.1 Introduction
14.2 Healthcare application areas for nanotechnology
  14.2.1 Biomedical research
  14.2.2 Therapeutics
  14.2.3 Diagnostics
14.3 Burning issues and trends
  14.3.1 Regulatory & health issues
  14.3.2 Increase in funding
14.4 Atomic force microscopy (AFM)
14.5 Nano-mass spectroscopy
14.6 Dip-pen Nanolithography

15 GEOGRAPHICAL ANALYSIS

15.1 Introduction
15.2 North America
15.3 Europe
15.4 Asia
15.5 ROW

16 COMPETITIVE LANDSCAPE

16.1 Market share for drug discovery technologies
16.2 Agreements & collaborations
16.3 New product launch
16.4 End clients for top 10 drug discovery technologies

17 COMPANY PROFILES

17.1 ABBOTT LABORATORIES INC.
  17.1.1 Overview
  17.1.2 Primary business
  17.1.3 Strategy
  17.1.4 Developments
17.2 AFFYMETRIX INC.
  17.2.1 Overview
  17.2.2 Primary business
  17.2.3 Strategy
  17.2.4 Developments
17.3 AGILENT TECHNOLOGIES INC.
  17.3.1 Overview
  17.3.2 Primary business
  17.3.3 Strategy
  17.3.4 Developments
17.4 ALBANY MOLECULAR RESEARCH INC.
  17.4.1 Overview
  17.4.2 Primary business
  17.4.3 Strategy
  17.4.4 Developments
17.5 ARQULE INC.
  17.5.1 Overview
  17.5.2 Primary business
  17.5.3 Strategy
  17.5.4 Developments
17.6 ASTRAZENECA PLC.
  17.6.1 Overview
  17.6.2 Primary business
  17.6.3 Strategy
  17.6.4 Developments
17.7 BIO-RAD LABORATORIES INC.
  17.7.1 Overview
  17.7.2 Primary business
  17.7.3 Strategy
  17.7.4 Developments
17.8 CALIPER LIFE SCIENCES INC.
  17.8.1 Overview
  17.8.2 Primary business
  17.8.3 Strategy
  17.8.4 Developments
17.9 CELERA CORP
  17.9.1 Overview
  17.9.2 Primary business
  17.9.3 Strategy
  17.9.4 Developments
17.10 CHARLES RIVER LABORATORIES INTERNATIONAL INC.
  17.10.1 Overview
  17.10.2 Primary business
  17.10.3 Strategy
  17.10.4 Developments
17.11 CHEMBRIDGE CORP
  17.11.1 Overview
  17.11.2 Primary business
  17.11.3 Strategy
  17.11.4 Developments
17.12 EVOTEC AG
  17.12.1 Overview
  17.12.2 Primary business
  17.12.3 Strategy
  17.12.4 Developments
17.13 F. HOFFMANN-LA ROCHE LTD.
  17.13.1 Overview
  17.13.2 Primary business
  17.13.3 Strategy
  17.13.4 Developments
17.14 GYROS AB
  17.14.1 Overview
  17.14.2 Primary business
  17.14.3 Strategy
  17.14.4 Developments
17.15 INCYTE CORP
  17.15.1 Overview
  17.15.2 Primary business
  17.15.3 Strategy
  17.15.4 Developments
17.16 LIFE TECHNOLOGIES CORP
  17.16.1 Overview
  17.16.2 Primary business
  17.16.3 Strategy
  17.16.4 Developments
17.17 SHIMADZU CORP
  17.17.1 Overview
  17.17.2 Primary business
  17.17.3 Strategy
  17.17.4 Developments
17.18 PERKINELMER INC.
  17.18.1 Overview
  17.18.2 Primary business
  17.18.3 Strategy
  17.18.4 Developments
17.19 SIGMA-ALDRICH CORP
  17.19.1 Overview
  17.19.2 Primary business
  17.19.3 Strategy
  17.19.4 Developments
17.20 TECAN GROUP LTD.
  17.20.1 Overview
  17.20.2 Primary business
  17.20.3 Strategy
  17.20.4 Developments
17.21 THERMO FISHER SCIENTIFIC INC.
  17.21.1 Overview
  17.21.2 Primary business
  17.21.3 Strategy
  17.21.4 Developments

APPENDIX

U.S. patents
EUROPE patents
JAPAN patents

LIST OF TABLES

1 Global top 10 drug discovery technologies market 2008 – 2015 ($Million)
2 Estimated time saving by CRO in clinical trials
3 Global high throughput screening market, by products 2008 – 2015 ($Million)
4 High throughput screening market, by geography 2008 – 2015 ($Million)
5 HTS infrastructural/resource comparison for pharmaceutical and academic centers
6 Ultra high throughput screening market, by geography 2008 – 2015 ($Million)
7 Robotics and automation market, by geography 2008 – 2015 ($Million)
8 Miniaturization market, by geography 2008 – 2015 ($Million)
9 High content screening market, by geography 2008 – 2015 ($Million)
10 Cell based assays market, by geography 2008 – 2015 ($Million)
11 Global bioanalytical instruments market, by products 2008 – 2015 ($Million)
12 Bioanalytical instruments market, by geography 2008 – 2015 ($Million)
13 Global mass spectrometry market, by products 2008 – 2015 ($Million)
14 Mass spectrometry market, by geography 2008 – 2015 ($Million)
15 Microplate Readers Market, By Geography 2008 – 2015 ($Million)
16 NMR market, by geography 2008 – 2015 ($Million)
17 Chemotherapy instruments market, by geography 2008 – 2015 ($Million)
18 Pharmacogenomics market, by geography 2008 – 2015 ($Million)
19 Combinatorial chemistry market, by geography 2008 – 2015 ($Million)
20 Cost comparison between traditional and combinatorial chemistry
21 Global genomics market, by products 2008 – 2015 ($Million)
22 Genomics market, by geography 2008 – 2015 ($Million)
23 Functional genomics market, by geography 2008 – 2015 ($Million)
24 Structural genomics market, by geography 2008 – 2015 ($Million)
25 Global biochips market, by segment 2008 – 2015 ($Million)
26 Biochips market, by geography 2008 – 2015 ($Million)
27 Patent disputes within the biochips market
28 DNA microarrays market, by geography 2008 – 2015 ($Million)
29 Lab on a chip market, by geography 2008 – 2015 ($Million)
30 Proteomics microarrays market, by geography 2008 – 2015 ($Million)
31 Global bioinformatics market, by products 2008 – 2015 ($Million)
32 Bioinformatics market, by geography 2008 – 2015 ($Million)
33 Global proteomics market, by products2008 – 2015 ($Million)
34 Proteomics market, by geography 2008 – 2015 ($Million)
35 2DGE market, by geography 2008 – 2015 ($Million)
36 Two hybrid systems market, by geography 2008 – 2015 ($Million)
37 Global RNAi market, by products 2008 – 2015 ($Million)
38 RNAi market, by geography 2008 – 2015 ($Million)
39 SiRNA market, by geography 2008 – 2015 ($Million)
40 MiRNA market, by geography 2008 – 2015 ($Million)
41 Global other RNAi technologies market, by products 2008 – 2015 ($Million)
42 Other RNAi technologies market, by geography 2008 – 2015 ($Million)
43 Global nanotechnology market, by products 2008 – 2015 ($Million)
44 Nanotechnology market, by geography 2008 – 2015 ($Million)
45 Comparison of AFM technology with other microscopy technology
46 Atomic force microscopy market, by geography 2008 – 2015 ($Million)
47 Nano-mass spectroscopy market, by geography 2008 – 2015 ($Million)
48 Dip-pen Nanolithography market, by geography 2008 – 2015 ($Million)
49 North American top 10 drug discovery technologies market 2008 – 2015 ($Million)
50 European top 10 drug discovery technologies market 2008 – 2015 ($Million)
51 Asian top 10 drug discovery technologies market 2008 – 2015 ($Million)
52 RoW top 10 drug discovery technologies market 2008 – 2015 ($Million)
53 Agreements and collaborations (2009 – 2010)
54 New product development (2009 – 2010)

LIST OF FIGURES

1 Revenue analysis for top 10 drug discovery technologies
2 Top 10 drug discovery technologies market segmentation
3 Relative market scenario (2010)
4 Patent analysis by geography
5 Patent analysis by competitors 2005 – 2010
6 High throughput screening in drug discovery
7 Approximate industrial demand for bioanalytical instruments (2010)
8 Cost saving in comparison with high throughput screening
9 Approximate end client share for microplate readers
10 Drug development process and pharmacogenomics applications
11 Future advancements in the pharmacogenomics research
12 Cost associated with pharmacogenomics based tests
13 Long term goals/benefits for pharmacogenomics
14 Dollar value offered, by technology providers
15 Time and cost saving by implementation of combinatorial chemistry
16 Reducing costs for whole genome sequencing
17 Major end clients for biochip technology market
18 Historical data for DNA microarray based collaborations
19 Applications of lab-on-a-chip technology in drug discovery
20 MiRNA research efforts
21 Applications areas of MiRNA
22 MiRNA in drug discovery
23 Nanotechnology applications
24 Global market for top 10 drug discovery technologies
25 Approximate market share for overall drug discovery technologies
26 Approximate end client share for top 10 drug discovery technologies
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