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The Roche Intelligence Dossier

November 2009 | 48 pages | ID: RE5B1B1EFDEEN
FirstWord

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As the fourth largest pharmaceutical company in the world, with annual revenues of $43.9 billion, some of the most instantly recognisable drugs marketed and the kind of pipeline smaller companies only dream of, Roche’s performance seems beyond reproach.

The headlines speak for themselves: While pharmaceutical revenues rose 11 per cent in Q3, boosted by sales of Tamiflu, net income at Roche Group fell 29 per cent in the first half of 2009, as the cost of the Genentech deal took effect. The FDA approved Valcyte for paediatric indication and Avastin for renal cancer, while the EMEA gave the nod to MabThera for rheumatic arthritis. On the corporate landscape, the company announced the buyout by Genentech of Lonza’s cell culture biologic manufacturing facility in Singapore for $360 million, while appointing new C-level executives.

But behind the glowing headlines lies another story. Despite facing just one more year of debt repayment for the Genentech takeover, Roche recently announced layoffs in the company’s late-stage drug development and administration areas. What’s more, while several key drug profiles such as Xenical and Xolair are under review by the FDA, the company is facing stiff competition from Tamiflu generics and an increasingly aggressive antiviral development market.

In six months of Roche’s major successes and setbacks, the question is: How does the positive news balance against the negative?

Key insights on critical developments at Roche

The Roche Intelligence Dossier — the second in FirstWord’s new series — delves behind the headlines of 125 articles on Roche’s Q2 and Q3 developments, to review the events forming the company’s present and future. In the 40-plus page dossier, FirstWord discusses not just the content of news reports, but offers visual breakdowns charting their positive or negative spin and how that affects Roche’s brand perception.

The report reviews Roche’s Q2 and Q3 developments to establish:
  • Critical trends in news reports of Roche’s corporate, financial, product and R&D resources
  • Key areas of importance affecting Roche’s outlook to give competitors significant insight

The report
  • Offers a detailed overview of all reported developments, events and corporate adjustments for the past two financial quarters
  • Discusses key positives in media reports, such as revenue recovery, drug developments, approvals and corporate appointments as well as negative news surrounding competition from generics, setbacks in regulatory rulings and drug reviews as well as financial and administrative issues
  • Updates on clinical trial results, terminations or approval applications for prominent drug profiles such as Avastin, Herceptin, XELODA, Lucentis, MabThera and Actemra.
  • Examines current R&D threads, as well as those being developed by competition
  • Offers a general company overview, stakeholder details, up-to-date financials and extensive charting of the Phase III pipeline.
ROCHE COMPANY OVERVIEW

NEWS ANALYSIS

NEWS BREAKDOWN

Q3 NEWS ON ROCHE

Positive News
  Drug and Research News
    Avastin (bevacizumab)
    Xeloda (capecitabine)
    Herceptin (trastuzumab)
    Lucentis (ranibizumab)
    Rituxan/MabThera ((rituximab)
    Actemra (tocilizumab)
    Tarceva (erlotinib)
    Valcyte (valganciclovir)
    Tamiflu (oseltamivir)
    Pegasys (peginterferon alpha 2a)
    CellCept (mycophenolate mofetil)
    Early Stage Developments
    GDC-0449
    PLX4032
    G7227/ITMN-191
    rHuPH20
    EVT 103
  Corporate News
    Mergers/Acquisitions
    Appointments
    Partnerships
    Job Cuts
    Financial News
    Negative news

Q2 NEWS ON ROCHE

Positive News
Negative news

ROCHE - BACKGROUND INFORMATION

Key Executives
  Roche Corporate Executive Committee Effective January 1, 2010
Stakeholder Engagement
Finance
Research and Development
  Roche’s Filed Compounds
  Roche’s Phase III Compounds

INDEX

APPENDIX

Q3 NEWS HEADLINES
Q2 NEWS HEADLINES


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