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Gene Amplification Technologies: Market Research Report

January 2012 | 529 pages | ID: G6792BF5159EN
Global Industry Analysts, Inc

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This report analyzes the worldwide markets for Gene Amplification Technologies in US$ Million by the following Product Segments: Polymerase Chain Reaction, and Other Gene Amplification Technologies.

The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World.

Annual estimates and forecasts are provided for the period 2009 through 2017.

Also, a six-year historic analysis is provided for these markets.

The report profiles 90 companies including many key and niche players such as Abbott Laboratories, Becton, Dickinson and Company, bioMerieux, Bio-Rad Laboratories, Cepheid, Life Technologies Corp., QIAGEN N.V, Roche Diagnostics, Rubicon Genomics, and Takara Bio, Inc.

Market data and analytics are derived from primary and secondary research.

Company profiles are primarily based upon search engine sources in the public domain.
I.INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
Definitions
Polymerase Chain Reaction
Other Gene Amplification Technologies

II. EXECUTIVE SUMMARY

1.INDUSTRY OVERVIEW

PCR Dominates Amplification Technologies
Growth Prospects Live in PCR Market despite Competition
Miniaturization – The Next Big Focus
Critical in Diagnostic Procedures
Leading Players

2.TECHNOLOGY OVERVIEW

Definition of Gene Amplification
Target vs. Signal Amplification
Available Types of Gene Amplification Technologies
Polymerase Chain Reaction
Reagents and Equipment required for PCR
Reaction Steps
Denaturation
Annealing
Extension
Detection of Amplified Product/DNA

(Q&Q) PCR

Reverse Transcriptase PCR (RT-PCR)
Alternative Technologies to PCR
OmniPlex
Strand Displacement Amplification
Ligase Chain Reaction
LCR Involves a Cyclic Two-Step Reaction
Gene Amplification Technology (GAT)
Hybrid Capture
Isothermal DNA Amplification Techniques
Rolling circle Amplification in Diagnostics
Ican Isothermal Gene Amplification Technology
BioHelix HDA Technology
Other Amplification Technologies
Signal Amplification Technology
Transcription Mediated Amplification
DNA cleavage-based signal amplification
Ramification Amplification Method

3.END-USE MARKET ANALYSIS

Medical and Diagnostics
Role of Amplification Technology in the Diagnoses of Infectious Diseases
Diagnosis of Infectious Diseases by PCR
Detection of Antimicrobial Resistance
PCR Based Nucleic Acid Amplification for Detection of Antimicrobial Agents
Nucleic Acid Amplification Testing (NAT)
Nucleic Acid Amplification Methods
DNA Amplification Technology in the Diagnosis of Infectious Diseases
Forensic and Paternity Testing
Food Safety

4.PRODUCT INNOVATIONS/LAUNCHES

DuPont Qualicon Launches New BAX® System Real-Time PCR Assay
Rubicon Genomics Launches PicoPlex Single Cell WGA Kit
NuGEN Unveils WT-OvationTM RNA Amplification System for Whole-Transcriptome Gene Expression Analysis
DuPont Qualicon Obtains Approval from Russian Federal Consumer Rights Protection and Human Health Control Service for BAX™ System
DuPont Qualicon Receives Approval from the General Administration of Quality Supervision, Inspection and Quarantine for BAX® system
Seegene Enters into Partnership with Shimadzu
Bio-Rad Launches New CFX96 PCR Detection System

5.PRODUCT INNOVATIONS/LAUNCHES IN RECENT PAST – A PERSPECTIVE BUILDER

Roche Introduces Genome Sequencer FLX System
QIAGEN Launches TopTaq DNA Polymerase
Applied Biosystems Introduces TaqMan Array Human MicroRNA Panel
Spartan Introduces Spartan DX
Applied Biosystems Launches Forensic Tools
Applied Biosystems Introduces StepOne Real-Time PCR System
Sigma-Aldrich Unveils GenomePlex Tissue Whole Genome Amplification Kit
QIAGEN Rolls Out Wide RNAi and SYBR® Green-based RT- PCR
Applied Biosystems Launches 7500 Fast Real-Time PCR System
Applied Biosystems Launches 9800 Fast PCR System

7900HT FAST REAL-TIME PCR SYSTEM FROM APPLIED BIOSYSTEMS

Enzo Life Sciences Introduces New Advanced Amplification Technology
Applied Biosystems Unveils AmpFSTR® Yfiler™ PCR Amplification Kit
Amersham Launches GenomiPhi
Rubicon Genomics Launches GenomePlex WGA
Agilent Introduces Amplification Kit
Linden Introduces Snapshot mRNA
Rubicon Launches OmniPlex™

6.RECENT INDUSTRY ACTIVITY

QIAGEN Acquires Rights to 70 Molecular Food Safety Tests from ifp
Life Technologies to Acquire Geneart
Thermo Fisher Scientific Takes Over Finnzymes
Abbott Inks Agreement with GlaxoSmithKline for Developing Molecular Diagnostic Test
DXS Purchases License for P13K Gene from Johns Hopkins University
Qiagen Acquires SABiosciences
DuPont Qualicon Obtains License from DxS for Scorpions® Technology
BD Takes Over HandyLab
Life Technologies Takes Over BioTrove
Merck Merges with Schering-Plough
QIAGEN Acquires Licenses from Idaho Technology and Roche
Response Genetics Inks Non-Exclusive Agreement with Roche Diagnostics
Invitrogen Announces Merger with Applied Biosystems
Hologic Acquires Third Wave Technologies
BIOTECON Acquires Roche's Technology License
QIAGEN Signs a Global Licensing Agreement with BioHelix
BioTrove and Gene Express Receive NIH Grant for Innovative Bio-experimentation

7.CORPORATE ACTIVITY IN THE RECENT PAST – A PERSPECTIVE BUILDER

SuperArray Bioscience Inks License Agreement with Applied Biosystems
Merck Capital Takes Over Minority Interest in High Throughput Genomics
NuGEN Enters into a Service Agreement with ExonHit
Qiagen Enters into License Agreements with Roche and Ortho-Clinical
Agilent Takes Over Stratagene
Eiken Chemical Inks Licensing Agreement with Meridian Bioscience
Sigma-Aldrich Acquires JRH
Sigma-Aldrich Snaps Up Proligo
Beckman Acquires Agencourt
Roche Diagnostics and Applera Corporation Expand PCR Licensing Program
Mount and Hamilton Receive Patent
Invitrogen Bags License from Applied Biosystems
OriGene to Access TrueClone
Orchid BioSciences to Turn into Orchid Cellmark
QIAGEN Purchases Assets of Molecular Staging
Cepheid, Applied Biosystems and Celera Diagnostics Sign Patent License Agreement
Abbott Enters into Agreement with BioGenex
Roche Inks Licensing Agreement with Incyte Corp
Rubicon Genomics Signs Licensing Agreement with Sigma-Aldrich
BioMérieux Teams-up with Cepheid
Molecular Staging Collaborates with Eli Lilly
Pacific Biometrics Inc. Receives Gene Amplification Patent
Rubicon Introduces Service for Genome Amplification
Takara Obtains Patent for New Amplification Method

8.FOCUS ON SELECT GLOBAL PLAYERS

Abbott Laboratories (US)
Becton, Dickinson and Company (US)
bioMérieux (France)
Bio-Rad Laboratories (US)
Cepheid (US)
Life Technologies Corp. (US)
QIAGEN N.V. (The Netherlands)
Roche Diagnostics (Switzerland)
Rubicon Genomics (US)
Takara Bio, Inc.

9.GLOBAL MARKET PERSPECTIVE

Table 1. World Recent Past, Current & Future Market Analysis for Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 2. World Historic Review for Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 3. World 15-Year Perspective for Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)
Table 4. World Recent Past, Current & Future Market Analysis for Polymerase Chain Reaction (PCR) by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 5. World Historic Review for Polymerase Chain Reaction (PCR) by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 6. World 15-Year Perspective for Polymerase Chain Reaction (PCR) by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)
Table 7. World Recent Past, Current & Future Market Analysis for Other Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 8. World Historic Review for Other Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 9. World 15-Year Perspective for Other Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)

III. MARKET

1.THE UNITED STATES

A. Market Analysis
Real-Time PCR Market in North America: A Primer

Table 10. Leading Suppliers of Individual qPCR Reagents in North America (2008): Percentage Dollar Share Breakdown of Invitrogen, Applied Biosystems, Roche Applied, Bio-Rad/ MJ, BD Clontech, Promega, Amblon, NEB, Qiagen, and Others (includes corresponding Graph/Chart)

Key Factors (Ranked in Order) in Selection of Real-Time/qPCR Platforms Manufacturers
Top 10 Research Applications of Real-Time Quantitative PCR (qPCR) in North America
B. Market Analytics

Table 11. US Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 12. US Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 13. US 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

2.CANADA

Market Analysis

Table 14. Canadian Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 15. Canadian Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 16. Canadian 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

3.JAPAN

Market Analysis

Table 17. Japanese Recent Past, Current & Future nalysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 18. Japanese Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 19. Japanese 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

4.EUROPE

Market Analysis

Table 20. European Recent Past, Current & Future Analysis for Gene Amplification Technologies by Geographic Region – France, Germany, UK, Italy, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 21. European Historic Review for Gene Amplification Technologies by Geographic Region – France, Germany, UK, Italy, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 22. European 15-Year Perspective for Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for France, Germany, UK, Italy, & Rest of Europe Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart) (includes corresponding Graph/Chart)
Table 23. European Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 24. European Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 25. European 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

4A.FRANCE

Market Analysis

Table 26. French Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 27. French Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 28. French 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

4B.GERMANY

Market Analysis

Table 29. German Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 30. German Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 31. German 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

4C.ITALY

Market Analysis

Table 32. Italian Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 33. Italian Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 34. Italian 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

4D.THE UNITED KINGDOM

Market Analysis

Table 35. UK Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 36. UK Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 37. UK 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

4E.REST OF EUROPE

Market Analysis

Table 38. Rest of Europe Market for Gene Amplification Technologies - Recent Past, Current & Future Market Analysis by Segment for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 39. Rest of Europe Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 40. Rest of Europe 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017

5.REST OF WORLD

Market Analysis

Table 41. Rest of World Market for Gene Amplification Technologies - Recent Past, Current & Future Market Analysis by Segment for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 42. Rest of World Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 43. Rest of World 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 90 (including Divisions/Subsidiaries - 104)
Region/CountryPlayers
The United States
Canada
Japan
Europe
France
Germany
The United Kingdom
Italy
Spain
Rest of Europe
Asia-Pacific (Excluding Japan)


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