2012 Germany Cancer Diagnostics Market Outlook: Growth Opportunities and Strategies

Date: April 17, 2012
Pages: 585
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Report type: Strategic Report
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2012 Germany Cancer Diagnostics Market Outlook: Growth Opportunities and Strategies
This report presents a comprehensive analysis of the German cancer diagnostics market, including:
  • Major issues pertaining to the German laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years.
  • Mortality statistics and scientific views on the etiology of major types of cancer, e.g., lung, colorectal, breast, prostatic, pancreatic, leukemia, lymphoma, gastrointestinal, bladder, liver, ovarian, testicular, oral, skin and others.
  • Ten-year test volume and sales forecasts for 40 cancer diagnostic procedures performed in German hospitals, commercial laboratories and physician offices.
  • Placements and installed base of automated and semiautomated analyzers used for cancer testing.
  • Current instrumentation technologies and feature comparison of leading analyzers.
  • Sales and market shares of leading suppliers.
  • Emerging diagnostic technologies and their potential market applications.
  • Product development opportunities.
  • Profiles of current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
  • Business opportunities and strategic recommendations for suppliers.
Contains 585 pages and 95 tables.
INTRODUCTION

WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW

A. CANCER STATISTICS AND ETIOLOGY


1. Brest Cancer
2. Lung Cancer
3. Colon and Rectum Cancer
4. Prostate Cancer
5. Stomach Cancer
6. Leukemia
7. Lymphoma
8. Oral Cancer
9. Skin Cancer
10. Uterine Cancer
11. Ovarian Cancer
12. Bladder Cancer

B. MAJOR CURRENT AND EMERGING CANCER DIAGNOSTIC TESTS

1. Introduction
2. Tumor Marker Classification
3. ACTH
4. Alpha-Fetoprotein (AFP)
5. Beta-2 Microglobulin
6. CA 15-3/27.29
7. CA 19-9
8. CA-125
9. Calcitonin
10. Carcinoembrionic Antigen (CEA)
11. Estrogen and Progesterone Receptors
12. Ferritin
13. Gastrin
14. Human Chorionic Gonadotropin (HCG)
15. Insulin
16. NSE
17. Occult Blood
18. PAP Smear/HPV
19. Prostatic Acid Phosphatase (PAP)
20. Prostate-Specific Antigen (PSA)
21. Squamous Cell Carcinoma Antigen (SCC)
22. T and B Lymphocytes
23. TdT
24. Thyroglobulin
25. Tissue Polypeptide Antigen (TPA)
26. Biochemical Tumor Markers
  ADA
  B-Protein
  PNP
  5'-Nucleotidase
27. Oncogenes
  Abl/abl-bcr
  AIB1
  BCL-2
  BRCA1
  CD44
  C-fos
  C-myb
  C-myc
  CYP-17
  Erb-B
  HPC1
  N-myc
  P40
  P51
  P53
  PIK3CA
  PTI-1
  Ras
  Reg
  Sis
  Src
28. Polypeptide Growth Factors
  Basic Fibroblast Growth Factor
  Beta-TGF
  Cachectin (TNT)
  Calmodulin
  ECFR
  Nerve Growth Factor (NGF)
  Epidermal Growth Factor (EGF)
  Ornithine Decarboxylase
  Transferrin
  Transforming Growth Factor-Alpha
29. Ectopic Hormones
30. Colony Stimulating Factors
31. Lymphokines
  Alpha-Interferon
  B Cell Growth Factors
  B Cell Growth Factor (BCGF)
  Gamma-Interferon
  Interleukin-1 (IL-1)
  Macrophage Activating Factor
32. Immunohistochemical Stains
33. Emerging Tumor Markers
  N-Acetylglucosamine
  Actin
  Alpha-Actin
  Antineuronal Antibodies
  7B2
  B72.3
  Bax
  BCD-F9
  BLCA-4
  Blood Group Antigens A,B,H
  CA 50
  CA 72-4/TAG-72
  CA 195
  CA-242
  CA-549
  CAM 26
  CAR-3
  Cathepsin-D
  Chromogranin A and B
  Cluster 1 Antigen
  Cluster-5/5A Antigen
  CTA
  CU18
  DR-70
  DU-PAN-2
  Endometrial Bleeding Associated Factor
  Endostatin
  Epithelial Membrane Antigen
  Feulgen Hydrolysis
  Fibronectin
  FSH
  (1->3)-L-fucosyltransferase
  Gastrin-Releasing Peptide (GRP)
  GDCFP-15
  Glucagon
  Glycoamines
  H23
  Her-2
  Human Carcinoma Antigen
  HPA
  HSP27
  Intermediate Filaments
    Cytokeratins/CK18/Cyfra 21-1
    Desmin
    Gliofibrillary Acid Protein
    Neurofilaments
    Vimentin
  KA 93
  Kinases
  KP16D3
  LAI
  Leukocyte Common Antigen
  Lewis Antigens
  Lysophosphatidic Acid (LPA)
  Ma 695/Ma 552
  MABDF3
  MAG
  ME1
  Minactivin
  MN/CA9
  MSA
  Mucin Cancer Antigen (MCA)
  Multiple Tumor Suppressor 1
  Myosin
  NEA-130
  NMP22
  OA-519
  Opiod Peptides
  P-glycoprotein
  Pancreatic Oncofetal Antigen (POA)
  Placental Lactogen
  PR92
  Proliferative Index, Ki-67
  Px
  RB Inactivation/Deletion
  Ret
  SCCL 175
  Selectin
  Sialic Acid
  Sialyl SSEA-1/SLX
  SN10
  Somatostatin
  TA-90
  TABA
  Tachykinin
  TAG 12
  TPS
  Troponin
  Tubulin
  VCAM
  VEGF
  Villen

C. INSTRUMENTATION REVIEW AND MARKET NEEDS

1. Abbott AxSYM
2. Abbott Architect c4000
3. Abbott Architect i2000 Series
4. Abbott Architect ci8200 System
5. Beckman Coulter UniCel Series
6. Beckman Coulter Access
7. Binding Site ESP600
8. bioMerieux Mini Vidas
9. Carolina Chemistries BioLis 24i
10. DiaSorin Liaison
11. Horiba ABX Pentra 400
12. Inverness DS2
13. J&J Vitros ECi/ECiQ
14. J&J Vitros 3600
15. J&J Vitros 5600
16. Olympus AU5400
17. Olympus AU3000i
18. Olympus AU2700
19. Roche Modular Analytics
20. Roche Cobas Integra 400
21. Roche Cobas Integra 400 Plus
22. Roche Elecsys
23. Roche Cobas c311
24. Siemens ADVIA Centaur
25. Siemens Dimension
26. Siemens Dimension RxL Max
27. Siemens Dimension Vista 500
28. Siemens Immulite
29. Siemens Stratus
30. Tosoh AIA-Series
31. Vital Diagnostics ATAC 8000
32. Vital Diagnostics Envoy 500

D. CURRENT AND EMERGING TECHNOLOGIES

1. Monoclonal and Polyclonal Antibodies
2. Immunoassays
  a. Technological Principle
  b. Radioimmunoassay (RIA)
  c. Enzyme Immunoassays (EIA)
    Overview
    ELISA
    Immunofiltration
    Particle-Membrane Capture Immunoassay
    Enzyme Amplification
  d. Fluorescent Immunoassays
  e. Luminescence
    Chemiluminescence
    Bioluminescence
  f. Latex Agglutination
  g. Immunoprecipitation
  h. Affinity Chromatographu
  e. Liposome Flow-Injection Immunoassay
3. Molecular Diagnostics
  a. Technology Overview
  b. Amplification Methods
    PCR
    DAP-PCR
    Immuno-PCR
    QC-PCR
    CAR
    DNA
    HPA
    LCR
    NASBA
    QBR
    SDA
    3 SR, and others
4. Chromosome Analysis
  a. Chronic Myelogenous Leukemia (CML)
  b. Acute Myeloid Leukemia (AML)
  c. Acute Lymphoblastic Leukemia (ALL)
  d. Malignant Lymphomas Lymphoid Malignancies
  e. Chronic Lymphocytic Leukemia (CLL)
  f. Solid Cancers
  g. Chromosomal Translocation and Oncogenes
5. Artificial Intelligence
6. Flow Cytometry
7. Two Dimensional Gel Electrophoresis (2-DGE)
8. Biosensors
9. Competing/Complementing Technologies
  a. CT
  b. MRI
  c. NMR
  d. PET
  e. Photonics Spectroscopy

E. PERSONAL TESTING

GERMANY


A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

MAJOR PRODUCT DEVELOPMENT OPPORTUNITIES

A. Reagent Kits and Test Systems/Panels
B. Instrumentation
C. Computers, Software and Automation
D. Auxiliary Products

DESIGN CRITERIA FOR DECENTRALIZED TESTING PRODUCTS

ALTERNATIVE MARKET PENETRATION STRATEGIES


A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies
  1. Marketing Approaches
  2. Product Complexity
  3. Customer Preference
  4. Established Suppliers
  5. Emerging Suppliers
  6. Major Types of Distributors
  7. Market Segmentation Factor

POTENTIAL MARKET ENTRY BARRIERS AND RISKS

A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

COMPETITIVE PROFILES

Abbott
AdnaGen
Applied Gene Technologies
Arca
Beckman Coulter/Danaher
Becton Dickinson
Biomedical Diagnostics
bioMerieux
Bio-Rad
Cepheid
Correlogic Systems
Dako
Decode
Diadexus
Diagnocure
Diasorin
Eiken Chemical
Enterix
Enzo Biochem
Epigenomics
Exact Sciences
Fujirebio
Gen-Probe
Guided Therapeutics
Hologic
Ipsogen
Kreatech
Kyowa Medex
Life Technologies
Mackay Life Sciences
Myriad Genetics
Nanogen Elitech
OncoLab
Otho-Clinical Diagnostics
Panacea Pharmaceuticals
Polartechnics
Polymedco
PreMD
Qiagen
Radient Pharmaceuticals
Roche
Scienion
Sequenom
Siemens Healthcare
Takara Bio
Targeted Diagnostics & Therapeutics
Tosoh
Veridex
Wako Pure Chemicals
Wallac/PE
Zila

APPENDIXES

Appendix I: Major Universities and Research Centers Developing Cancer Diagnostic Technology and Applications
Appendix II: Assumed Currency Exchange Rates

LIST OF TABLES

Tumor Marker Classification
Major Companies Developing or Marketing ACTH Tests
Major Companies Developing or Marketing AFP Tests
Major Companies Developing or Marketing Beta-2 Microglobulin Tests
Major Companies Developing or Marketing CA 15-3/27.29 Tests
Major Companies Developing or Marketing CA 19-9 Tests
Major Companies Developing or Marketing CA 125 Tests
Major Companies Developing or Marketing Calcitonin Tests
Major Companies Developing or Marketing CEA Tests
Major Companies Developing or Marketing Estrogen Receptor Tests
Major Companies Developing or Marketing Progesterone Receptor Tests
Major Companies Developing or Marketing Ferritin Tests
Major Companies Developing or Marketing Gastrin Tests
Major Companies Developing or Marketing HCG Tests
Major Companies Developing or Marketing Insulin Tests
Major Companies Developing or Marketing NSE Tests
Major Companies Developing or Marketing Occult Blood Tests
Major Companies Developing or Marketing PAP Smear/HPV Tests
Major Companies Developing or Marketing PAP Tests
Major Companies Developing or Marketing PSA Tests
Major Companies Developing or Marketing Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications In Cancer Diagnosis
Oncogenes Potential Applications In Cancer Diagnosis
Major Companies Developing or Marketing Oncogene Tests
Growth Factors Potential Applications In Cancer Diagnosis
Colony Stimulating Factors Potential Applications in Cancer Diagnosis
Lymphokines Potential Applications In Cancer Diagnosis
Immunohistochemical Stains Potential Applications in Cancer Diagnosis
Executive Summary Table: Germany, Total Tumor Marker Test Volume and Sales Forecast By Market Segment
Germany, Estimated Cancer Death Rates Per 100,000 Population
Germany, Laboratories Performing Tumor Marker Tests by Market Segment
Germany, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
Germany, Commercial/Private Laboratories Performing Tumor Markers by Annual Test Volume
Germany, Total Tumor Marker Test Volume Forecast by Market Segment
Germany, All Market Segments, Major Tumor Marker Test Volume Forecast
Germany, Hospital Laboratories, Major Tumor Marker Test Volume Forecast by Test
Germany, Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
Germany, Physician Offices/Group Practices Major Tumor Marker Test Volume Forecast
Germany, Total Tumor Marker Sales Forecast by Market Segment
Germany, All Market Segments Major Tumor Marker Sales Forecast by Test
Germany, Hospital Laboratories, Major Tumor Marker Sales Forecast by Test
Germany, Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
Germany, Physician Offices/Group Practices Major Tumor Marker Sales Forecast by Test
Germany, ACTH Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, AFP Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Beta-2 Microglobulin Test Volume And Diagnostics Sales Forecast by Market Segment
Germany, CA-15-3/27.29 Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, CA-19 Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, CA 125 Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Calcitonin Test Volume And Diagnostic Sales Forecast by Market Segment
Germany, Cathepsin Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, CEA Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Chromogranin Test Volume And Diagnostics Sales Forecast by Market Segment
Germany, Colon-Specific Antigen Test Volume And Diagnostics Sales Forecast by Market Segment
Germany, Cytokeratins Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Estrogen Receptor Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Ferritin Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Gastrin Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, HCG, Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Insulin Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Interferons Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Interleukins Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Lymphocyte Subtyping Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, NSE Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Occult Blood Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Oncogenes Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Pancreatic Oncofetal Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Pap Smear Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Parathyroid Hormone Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Progesterone Receptor Test Volume And Diagnostics Sales Forecast by Market Segment
Germany, PAP Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, PSA Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, S-100 Protein Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Serotonin Test Volume and Diagnostics Sales Forecast by Mar Segment
Germany, Sialic Acid Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Squamous Cell Carcinoma Antigen Test Volume and Diagnostics Sales Forecast By Market Segment
Germany, TDT Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Thymidine Kinase Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Thyroglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, TPA Test Volume and Diagnostics Sales Forecast by Market Segment
Germany, Total Tumor Marker Sales By Major Supplier
Germany, AFP Testing Market Diagnostics Sales by Major Supplier
Germany CA 15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
Germany CA 19-9 Testing Market Diagnostics Sales by Major Supplier
Germany, CA 125 Testing Market Diagnostics Sales by Major Supplier
Germany, CEA Testing Market Diagnostics Sales by Major Supplier
Germany, PSA Testing Market Diagnostics Sales by Major Supplier
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2012 Germany Cancer Diagnostics Market Outlook: Growth Opportunities and Strategies
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