DNA Sequencing: Role in Clinical Laboratories
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Rationale
This report presents a concise review of the DNA sequencing field, including discussion of such topics as sequencing methods, automation, detection, gene profiling, and expression, polymorphism, screening, protein interaction networks, and others.
Sequencing is expected to continue playing a major role in clinical laboratories, e.g., in detecting resistance mutations in viruses and bacteria, especially because of the rising availability of sequencing technologies and automated instrumentation.
Contains 15 pages
Rationale
This report presents a concise review of the DNA sequencing field, including discussion of such topics as sequencing methods, automation, detection, gene profiling, and expression, polymorphism, screening, protein interaction networks, and others.
Sequencing is expected to continue playing a major role in clinical laboratories, e.g., in detecting resistance mutations in viruses and bacteria, especially because of the rising availability of sequencing technologies and automated instrumentation.
Contains 15 pages
1. INTRODUCTION
2. SEQUENCING METHODS
3. AUTORADIOGRAPHY
4. THE HUMAN GENOME PROJECT
5. SEQUENCING AUTOMATION
6. IMAGE SCANNERS
7. FLUORESCENT DETECTION
8. GENE PROFILING
9. GENE EXPRESSION
10. POLYMORPHISM SCREENING
11. PROTEIN INTERACTION NETWORKS
2. SEQUENCING METHODS
3. AUTORADIOGRAPHY
4. THE HUMAN GENOME PROJECT
5. SEQUENCING AUTOMATION
6. IMAGE SCANNERS
7. FLUORESCENT DETECTION
8. GENE PROFILING
9. GENE EXPRESSION
10. POLYMORPHISM SCREENING
11. PROTEIN INTERACTION NETWORKS
