Artificial Organs: Market Research Report

Date: January 8, 2016
Pages: 248
Price:
US$ 4,500.00
Publisher: Global Industry Analysts, Inc
Report type: Strategic Report
Delivery: E-mail Delivery (PDF)
ID: A0867F9F2E0EN
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Artificial Organs: Market Research Report
This report analyzes the worldwide markets for Artificial Organs in US$ Million by the following Product Segments: Artificial Heart, Artificial Kidneys, Artificial Liver, Artificial Pancreas, and Artificial Lungs. The report provides separate comprehensive analytics for the US, and Rest of World. Annual estimates and forecasts are provided for the period 2015 through 2022.

Also, a six-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs.

The report profiles 48 companies including many key and niche players such as -
  • Abbott Diabetes Care, Inc.
  • Abiomed, Inc.
  • Asahi Kasei Medical Co., Ltd.
  • Baxter International, Inc.
  • F.Hoffmann-La Roche Ltd.
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
Artificial Organs
Artificial Heart
Artificial Kidneys
Artificial Liver
Artificial Pancreas
Artificial Lungs

II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW

Artificial Organs Revolutionize Medical Technology Industry
Growth Drivers
Growth Inhibitors
Artificial Organs Poised to Witness Significant Demand
The United States – A Dominant Force in the Artificial Organs Market
Artificial Kidneys Garner a Larger Pie in the Artificial Organs Market
Competitive Scenario
Technological Advancements Spearheading Growth

2. ANALYSIS BY SEGMENT

Artificial Heart

Table 1. Artificial Heart Transplants Worldwide (1969-2016): Percentage Share Breakdown of Number of Heart Transplants (includes corresponding Graph/Chart)

Medical Community Poised to Embrace Artificial Heart
Ventricular Assist Devices
Select Ventricular Assist Devices
Artificial Mechanical Heart Valves Come of Age
Artificial Kidney
Kidney Failure: A Major Concern
Artificial Kidney or Dialyzers Market
Major Initiatives in the Artificial Kidney Space
The Kidney Project
Current Status of the Kidney Project
Wearable Artificial Kidney Holds Promise to Transform Dialysis
Artificial Liver
Liver Support System to Provide Precious Time for Liver Transplantation
Liver Assist Devices Competitive Landscape
Select Liver Assist Devices
Artificial Pancreas
Artificial Pancreas Device System Market Presents Lucrative Opportunities
Market Overview
Scientific Community Inches towards Artificial Pancreas System
Competition and Key Developments in Artificial Pancreas Space
Artificial Pancreas Status in the US
Key Concerns

3. MARKET TRENDS AND ISSUES

The Grim Reality of Mounting Economic and Social Burden of Cardiovascular Disease

Table 2. Prevalence of Heart Failure in Select Countries (includes corresponding Graph/Chart)

Artificial Pancreas System (APS) – The Future of Diabetes Care
Higher Development Costs and Lengthy Regulatory Process – Stumbling Blocks for Product Commercialization
Lack of Requisite Expertise – Hindering Implantation Process
Xenotransplantation – Other Alternative to Donor Organ Shortage
Artificial Organs from Cloned Animal Cells – A Promising Trend
Immunosuppressants Hold Promise in Artificial Organs Market
Move towards Smaller Implantable Devices
Barriers to Entry Significantly High in Dialyzers Market
Reuse of Dialyzers – A Major Issue in Dialysis Industry
Poor Reimbursement Environment Stymies Innovation
Product Recalls – A Major Blow to the Manufacturers
Higher Cost of Artificial Organs Hampers Broader Adoption
Major Issues Related to Artificial Organs
Financial
Legal
Ethical
Social

4. MACRO FACTORS IMPACTING THE ARTIFICIAL ORGANS MARKET

Aging Population: A Strong Growth Driver
Global Aging Population Statistics – Opportunity Indicators

Table 3. Elderly Population (60+ Years) as a Percentage of Total Population (2015 & 2050) (includes corresponding Graph/Chart)
Table 4. Global Aging Population in Select Regions/Countries: Population of 60+ Individuals in ‘000s and as a Percentage of Total Population for 2015 & 2050 (includes corresponding Graph/Chart)
Table 5. Life Expectancy at Age 60 and 80 Years - (2010-2015), (2020-2025) & (2045-2050) (includes corresponding Graph/Chart)
Table 6. Life Expectancy for Select Countries in Number of Years: 2015E (includes corresponding Graph/Chart)

Expanding Pool of ESRD and CKD Patients – The Major Growth Driver for Kidney Dialysis Treatment

Table 7. Increasing Number of ESRD Patients Worldwide: 2014-2018 (includes corresponding Graph/Chart)
Table 8. ESRD Prevalence in Select Countries (2014): Number of ESRD Patients Per Million Population in EU-28, Japan, Taiwan, USA and Global (includes corresponding Graph/Chart)

Dialysis Market to Stage Steady Growth Amid Rising Prevalence of Kidney Diseases

Table 9. Global Population of ESRD Patients Undergoing Treatment by Type of Modality (2010, 2015E & 2020P): Percentage Breakdown of Patients Undergoing Dialysis Therapy, and Kidney Transplantation (includes corresponding Graph/Chart)

Developed Markets Maintain Lead, Emerging Markets to Dictate Momentum

Table 10. Worldwide Distribution of Dialysis Patients by Geographic Region (2015): Percentage Breakdown of Patient Population (includes corresponding Graph/Chart)

Rising Incidence of Diabetes: Opportunity Indicator for Artificial Pancreas
Growing Number of Type 1 Diabetes Cases
Global Diabetic Statistics - Opportunity Indicators

Table 11. Top 10 Countries for Number of Children with Type 1 Diabetes (2015) (includes corresponding Graph/Chart)
Table 12. Global Prevalence of Type 1 Diabetes in Children by Region (2015) (includes corresponding Graph/Chart)

A “Silent Killer” in Both Developed as well as Developing Nations

Table 13. Global Diabetes Mellitus Incidence among Ages 20-79 (2015 & 2040P): Prevalence (in Million) and Percentage Share by Geographic Region (includes corresponding Graph/Chart)
Table 14. Top Ten Countries Worldwide with the Highest Number of People (in the Age Group 20-79 Years) with DM (in Millions): 2015 (includes corresponding Graph/Chart)

Dialysis Patient Population: An Opportunity Indicator for Artificial KIdneys

Table 15. Global Dialysis Patient Population by Geographic Region/Country (2014-2018): Breakdown of Patient Population for US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World (includes corresponding Graph/Chart)

Distribution of Dialysis Patients by Modality

Table 16. Worldwide Dialysis Patient Population by Treatment Modality (2015): Percentage Breakdown of Hemodialysis (HD) Patients and Peritoneal Dialysis (PD) Patients for US, Japan, European Union, and Rest of World (includes corresponding Graph/Chart)
Table 17. Global Dialysis Patient Population Distribution by Modality for Select Countries (2015): Percentage Breakdown of Hemodialysis (HD) Patients and Peritoneal Dialysis (PD) Patients for US, China, Japan, Brazil, Mexico, Germany, India, Taiwan, Turkey, Thailand, Korea, Italy, France, Egypt, and Malaysia (includes corresponding Graph/Chart)

5. 3D BIOPRINTING – A GAME CHANGER FOR THE ARTIFICIAL ORGANS INDUSTRY

Application of 3D-Printing in the Medical Field
3D PRINTING REVOLUTIONIZING THE MEDICAL INDUSTRY’S ARTIFICIAL ORGAN DEVELOPMENT SEGMENT
Issues to be Tackled
Sophisticated Software – A Key Element for 3D Printing
Bioprinters to Aid Medical Students
Bioprinters to Print Organs
Bioprinters for Printing Defective Organs for Surgeons to Practice On

6. TECHNOLOGICAL ADVANCEMENTS

New Artificial Pancreas with Sensor to Improve Insulin Management
Researchers at the University of California Come Up with an Artificial Kidney
Wearable Artificial Kidney Enters the US FDA’s EAP Pipeline
New Artificial Pancreas System to Improve Diabetes Management
Production of 3D-like Artificial Organs in a Device that Works like a Cotton Candy Machine
Harvard Scientists Create Tissue Containing Blood Vessels
University of Washington Researchers Create Communicating Yeast Cells
ALung Technologies Develops Hemolung RAS Artificial Lung
The First Transplant of Small Sized Artificial Heart for Petite People Carried Out in California
Scientists Define Morphospace to Evaluate Viability of Artificial Organs

7. PRODUCT OVERVIEW

Artificial Organs
Categorization of Artificial Organs
External Artificial Organs
Internal or Implantable Artificial Devices
Artificial Heart
Total Artificial Heart (TAH)
Ventricle Assist Device (VAD)

Table 18. Distribution of Various Uses of VADs (includes corresponding Graph/Chart)

Right Ventricular Assist Systems (RVAS)
Left Ventricular Assist Systems (LVAS)
Categorization of LVAS
First Generation LVAS
Second Generation LVAS
Third Generation LVAS
Benefits of LVAS
Major Limitations and Complications of VADs
Infection
Internal Bleeding
Thrombus
Dependability
Cost
Natural Human Heart
Heart Diseases
Congenital Heart Disease
Congestive Heart Failure
Types of Heart Failure
Diastolic Heart Failure
Systolic Heart Failure
Artificial Heart - A Historical Perspective
Major Milestones in Artificial Heart Development
Jarvik-7
AbioCor Total Artificial Heart
CardioWest Temporary Total Artificial Heart
DuraHeart LVAS
HeartSaverVAD
VentrAssist Left Ventricular Assist Device
Artificial Kidney (Dialyzer)
Limitations of Artificial Kidney
Types of Dialysis
Hemodialysis
Peritoneal Dialysis
Advancements in Artificial Kidney Technology
Bioartificial Kidneys
Limitations of Bioartificial Kidneys
Hindrances to Develop Implantable Artificial Kidney
Artificial Kidneys - A Historical Perspective
Artificial Liver
Overdose of Drugs – A Leading Cause for Liver Damage
Categorization of Liver Devices
Mechanical Systems
Liver Dialysis Unit
Bio-Artificial Systems
Capillary Hollow Fiber Systems
Direct Perfusion Systems
Entrapment Based Systems
Major BAL Devices
Extracorporeal Liver Assist Device (ELAD)
Hybrid Artificial Liver Support System
History of Artificial Liver
Liver Assist Devices – Major Milestones
Nonbiological Method Introduction Time Line
Biological Method Introduction Time Line
Artificial Pancreas
Insulin Pumps - Historical Perspective
Bioartificial Pancreas
Nanotechnology in Artificial Pancreas
Artificial Lungs (Oxygenator)
About Human Lungs
Types of Artificial Lung
Intravenous Membrane Oxygenator
Hattler Respiratory Catheter
MC3 Pulmonary Assist Device
In-Series
In-Parallel
BioLung
Heart-Lung Bypass Machine
Role of Artificial Lungs during Surgery
Direct Contact Device
Indirect-Contact Type-Membrane Devices
Biorubber to be used in Artificial Lungs
History of Artificial Lungs
An Overview of Tissue Engineering

8. INTRODUCTION TO BIOMATERIALS

9. ORGAN TRANSPLANTATION

Europe and the United States Lead the Global Organ Transplants Market

Table 19. Global Organ Transplants Market (2014 & 2015): Number of Actual Deceased Organ Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 20. Global Organ Transplants Market (2014 & 2015): Number of Living Organ Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 21. Global Organ Transplants Market (2014): Number of Actual Donors After Cardiac Death Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 22. Global Heart Transplants Market (2014): Number of Transplants Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 23. Global Kidney Transplants Market (2014): Number of Deceased Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 24. Global Kidney Transplants Market (2014): Number of Living Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 25. Global Liver Transplants Market (2014): Number of Deceased Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 26. Global Liver Transplants Market (2014): Number of Living Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 27. Global Pancreas Transplants Market (2014): Number of Transplants Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 28. Global Lung Transplants Market (2014): Number of Transplants Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)

Sources of Donor Organs

Table 29. US Kidney Donations by Donor Type - Cadaveric and Living for Years 2010 through 2016 (includes corresponding Graph/Chart)
Table 30. US Liver Donations by Donor Type - Cadaveric and Living for Years 2010 through 2016 (includes corresponding Graph/Chart)
Table 31. US Heart Donations by Cadaveric Donor Type for Years 2010 through 2016 (includes corresponding Graph/Chart)
Table 32. US Lung Donations by Donor Type - Cadaveric and Living for Years 2010 through 2016 (includes corresponding Graph/Chart)
Table 33. US Pancreas Donations by Donor Type - Cadaveric and Living for Years 2010 through 2016 (includes corresponding Graph/Chart)
Table 34. European Organ Transplants Market (2014 & 2015): Number of Actual Deceased Organ Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)
Table 35. European Organ Transplants Market (2014 & 2015): Number of Living Organ Donors Per Million Population (PMP) by Select Country (includes corresponding Graph/Chart)

Shortage of Donor Organs Restricts Transplantation Procedures

Table 36. Waiting List of Patient Registrations in the US by Organ Type: As of July 2016 (includes corresponding Graph/Chart)

Organ Rejection – A Major Barrier to Transplantation
Other Issues for Organ Transplantation
Illegal Organ Trafficking – A Risky Proposition
Ethical Concerns in Transplants
Bioethical Issues Hinder Organ Donation Process
Increasing Consent Rates – A Key Factor
Combined Organ Transplantation – Gaining Attention
Transplant Tourism – Creating Brighter Avenues

10. REGULATORY ENVIRONMENT

Regulatory Environment in the US
Regulatory Environment in Europe

11. PRODUCT INNOVATIONS/INTRODUCTIONS

Medtronic Launches MiniMed(TM) 640G System
Pandorum Develops Artificial Human Liver Tissue

12. RECENT INDUSTRY ACTIVITY

Medtronic and HeartWare International Ink Merger Agreement
SynCardia Systems Inks an Agreement with Versa Capital Management
Vivonics Sells Artificial Lung Technology to Lung Biotechnology PBC
Insulet Corporation Enters into a Partnership and License Agreement with Mode AGC
Cellnovo Group Enters into a Partnership with TypeZero
St. Jude Medical Acquires Thoratec
Debiotech Collaborates with ARTORG Center to Develop Artificial Pancreas
DreaMed Diabetes Enters into an Agreement with Medtronic
Breethe Acquires Exclusive Rights from University of Maryland
SynCardia Systems Bags FDA Approval for SynCardia Temporary Total Artificial Heart’s Destination Therapy Study
HeartWare International Bags Approval from Health Canada for HeartWare Ventricular Assist System
Alung Technologies Announces Participation in the Pivotal Trial of ECCO2R Technology
ALung Technologies Announces EAP Designation for Hemolung RAS
Debiotech, AWAK and Neokidney Development Ink Join Venture Agreement
Carmat Implants Artificial Heart
Baxter International Acquires Gambro
Thoratec Acquires DuraHeart II from Terumo
Sunshine Heart Enters into Collaboration with Minnetronix(R)
TandemDiabetes Care Enters into a Partnership with JDRF

13. FOCUS ON SELECT GLOBAL PLAYERS

Abbott Diabetes Care, Inc. (USA)
Abiomed, Inc. (USA)
Asahi Kasei Medical Co. , Ltd. (Japan)
Baxter International, Inc. (USA)
F. Hoffmann-La Roche Ltd. (Switzerland)
Fresenius Medical Care AG & Co. KGaA (Germany)
HeartWare International, Inc. (USA)
Jarvik Heart, Inc. (USA)
Medtronic, Inc. (USA)
Nikkiso Co. , Ltd. (Japan)
Nipro Corporation (Japan)
SynCardia Systems, Inc. (USA)
Terumo Heart, Inc. (USA)
Thoratec Corp. (USA)
Toray Medical Co. , Ltd. (Japan)
Vital Therapies, Inc. (USA)
Xenios AG (Germany)

14. GLOBAL MARKET PERSPECTIVE

Table 37. World Recent Past, Current & Future Analysis for Artificial Organs by Geographic Region - US and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2015 through 2022 (includes corresponding Graph/Chart)
Table 38. World Historic Review for Artificial Organs by Geographic Region - US and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2014 (includes corresponding Graph/Chart)
Table 39. World 14-Year Perspective for Artificial Organs by Geographic Region - Percentage Breakdown of Dollar Sales for US and Rest of World Markets for Years 2009, 2016 & 2022 (includes corresponding Graph/Chart)
Table 40. World Recent Past, Current & Future Analysis for Artificial Organs by Product Segment - Artificial Heart, Artificial Kidneys, Artificial Liver, Artificial Pancreas and Artificial Lungs Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2015 through 2022 (includes corresponding Graph/Chart)
Table 41. World Historic Review for Artificial Organs by Product Segment - Artificial Heart, Artificial Kidneys, Artificial Liver, Artificial Pancreas and Artificial Lungs Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2014 (includes corresponding Graph/Chart)
Table 42. World 14-Year Perspective for Artificial Organs by Product Segment - Percentage Breakdown of Dollar Sales for Artificial Heart, Artificial Kidneys, Artificial Liver, Artificial Pancreas and Artificial Lungs Markets for Years 2009, 2016 & 2022 (includes corresponding Graph/Chart)
Table 43. World Recent Past, Current & Future Analysis for Artificial Kidneys/Dialyzers by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East & Africa, and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2015 through 2022 (includes corresponding Graph/Chart)
Table 44. World Historic Review for Artificial Kidneys/Dialyzers by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East & Africa, and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2014 (includes corresponding Graph/Chart)
Table 45. World 14-Year Perspective for Artificial Kidneys/Dialyzers by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East & Africa, and Latin American Markets for Years 2009, 2016 & 2022 (includes corresponding Graph/Chart)
Table 46. World Recent Past, Current & Future Analysis for Insulin Pumps (External) by Geographic Region - US, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)
Table 47. World Historic Review for Insulin Pumps (External) by Geographic Region - US, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)
Table 48. World 14-Year Perspective for Insulin Pumps (External) by Geographic Region - Percentage Breakdown of Dollar Sales for US, Europe and Rest of World Markets for Years 2009, 2016 & 2022 (includes corresponding Graph/Chart)

III. MARKET

1. THE UNITED STATES

A. Market Analysis
SynCardia’s temporary Total Artificial Heart: The Only FDA Approved Artificial Heart
Ageing Demographics: A Major Driving Factor for Artificial Organs Market

Table 49. North American Elderly Population by Age Group: 1975-2050 (includes corresponding Graph/Chart)

Surging Diabetic Population Spurs Demand

Table 50. Prevalence of Diabetes Mellitus in North America (2013 & 2035): Number of People with DM (in Thousands) in the 20-79 Age Group for the US, Canada and Mexico (includes corresponding Graph/Chart)
Table 51. The US Diabetics Population (2010-2017): Percentage Population with Diagnosed and Undiagnosed Diabetes (includes corresponding Graph/Chart)
Table 52. The US Diabetes Prevalence (in 000’s) for 2010-2017P (includes corresponding Graph/Chart)
Table 53. Diabetes Prevalence in the US by Type: 2013 (includes corresponding Graph/Chart)
Table 54. Diabetes Prevalence by Ethnicity (includes corresponding Graph/Chart)

Artificial Pancreas System (APS): The Future of Diabetes Management
Artificial Pancreas Status in the US
Wearable Artificial Kidney Holds Promise to Transform Dialysis
Product Introduction
Strategic Corporate Developments
Focus on Select Key Players
B. Market Analytics

Table 55. The US Recent Past, Current & Future Analysis for Artificial Organs Market Analyzed with Annual Sales Figures in US$ Million for Years 2015 through 2022 (includes corresponding Graph/Chart)
Table 56. The US Historic Review for Artificial Organs Market Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2014 (includes corresponding Graph/Chart)

2. REST OF WORLD

A. Market Analysis

Table 57. Dialysis Patient Population by Geographic Region/Country (2014-2018): Breakdown of Patient Population for Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World (includes corresponding Graph/Chart)
Table 58. Prevalence of Diabetes Mellitus in Europe (2013 & 2035): Number of People with DM (in thousands) in the 20-79 Age Group for 47 Countries in the Region
Table 59. Prevalence of Diabetes Mellitus in South East Asia (2013 & 2035): Number of People with DM (in thousands) in the 20-79 Age Group for Bangladesh, Bhutan, India, Maldives, Mauritius, Nepal, and Sri Lanka
Table 60. Prevalence of Diabetes Mellitus in Western Asia, Pacific Regions (2013 & 2035): Number of People with DM (in thousands) in the 20-79 Age Group for 27 Countries in the Region
Table 61. Prevalence of Diabetes Mellitus in South & Central America (2013 & 2035): Number of People with DM (in thousands) in the 20-79 Age Group for 20 Countries in the Region
Table 62. Prevalence of Diabetes Mellitus in Africa (2013 & 2035): Number of People with DM (in thousands) in the 20-79 Age Group for 27 Countries in the Region
Table 63. Prevalence of Diabetes Mellitus in Middle East & North Africa (2013 & 2035): Number of People with DM (in thousands) in the 20-79 Age Group for 19 Countries in the Region

New Artificial Pancreas System to Improve Diabetes Management
EU-Supported Artificial Pancreas Project to Provide Competitive Edge to Europe
Product Introduction
Strategic Corporate Developments
Focus on Select Players
B. Market Analytics

Table 64. Rest of World Recent Past, Current & Future Analysis for Artificial Organs Market Analyzed with Annual Sales Figures in US$ Million for Years 2015 through 2022 (includes corresponding Graph/Chart)
Table 65. Rest of World Historic Review for Artificial Organs Market Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2014 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 48 (including Divisions/Subsidiaries - 56)
The United States (25)
Japan (10)
Europe (15)
  France (3)
  Germany (5)
  The United Kingdom (2)
  Rest of Europe (5)
Asia-Pacific (Excluding Japan) (4)
Middle East (2)
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