Analysis of Emerging Molecular Diagnostics Tests And Strategic Profiles of Leading Suppliers
This 548-page report presents an overview of the clinical significance and market needs for major current and emerging tests, as well as extensive listings of companies developing and marketing molecular diagnostic technologies and products.
This report also presents strategic assessments of current and emerging suppliers of molecular diagnostic products, including of their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
Contains 548 pages and 22 tables
This report also presents strategic assessments of current and emerging suppliers of molecular diagnostic products, including of their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
Contains 548 pages and 22 tables
MICROBIOLOGY/INFECTIOUS DISEASES
a. Overview
b. Major Infectious Diseases
AIDS
Structure and Composition
Classification
AIDS Origins
Animal Lentivirus Systems
Virus Receptors
HIV Infections in Humans
Pathogenesis and Pathology
CD4T Lymphocytes and Memory Cells
Monocytes and Macrophages
Lymphoid Organs
Neural Cells
Viral Coinfections
Clinical Findings
Plasma Viral Load
Pediatric AIDS
Neurologic Disease
Opportunistic Infections
Cancer
Immunity
Virus Isolation
Serology
Viral Nucleic Acid/Antigen Detection
Epidemiology
Worldwide Spread of AIDS
United States
Routes of Transmission
DNA Probes
Overview
Quantitative PCR
In Situ PCR
Needed Improvements
Viral Load/Drug Resistance Testing
Genotype and Phenotype Testing
Blood Banking Considerations
Adenovirus
Background
Diagnostic Tests
Vaccines and Drugs
Adeno-Associated Viruses (AAV)
Anthrax/Bacillus Anthracis
Background
Diagnostic Tests
Vaccines and Drugs
Babesiosis
Background
BEA and Other Bartonella Diseases
Background
Diagnostic Tests
Vaccines and Drugs
Chagas Disease
Background
Campylobacter
Background
Diagnostic Tests
Culture Identification
Vaccines and Drugs
Chlamydia
Background
Chlamydia psittaci
Chlmaydia pneumoniae
Chlamydia trachomatis
Diagnostic Tests
Vaccines and Drugs
Creutzfeldt-Jakob’s Disease
Background
Blood Transmission
Diagnostic Tests
Major Commercial and Academic Players
Bayer
Disease Sciences/Bi-Tec Global
Imperial College School of Medicine
Ortho-Clinical Diagnostics
Pall
ProMetic Life Sciences
Proteome Sciences/Idexx
Q-One Biotech
Serono
U.S. Agricultural Research Service
Drugs
Vaccines
Cytomegalovirus
Background
Chorioretinitis
Gastrointestinal
Central Nervous System Disease
Diagnostic Tests
Vaccines and Drugs
Ebola Virus
Background
Epidemiology
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
EchoVirus
Background
Acute Aseptic Meningitisis
Encephalitis
Exanthems
Respiratory Disease
Myopericarditis
Neonatal Infections
Diagnostic Tests
Vaccines and Drugs
Encephalitis
Background
Diagnostic Tests
Vaccines and Drugs
Enteroviruses
Background
Diagnostic Tests
Viral Isolation and Identification
Antibody Tests
Vaccines and Drugs
Epstein-Barr Virus
Background
Diagnostic Tests
Vaccines and Drugs
Gonorrhea
Background
Diagnostic Tests
Vaccines and Drugs
Hepatitis
Hepatitis A
Hepatitis B
Structure and Composition
Replication
Hepatitis C
Hepatitis D (Delta)
Hepatitis E
Hepatitis G
Hepatitis Infections Pathology
Clinical Findings
Laboratory Tests
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Virus-Host Immune Reactions
Epidemiology
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D (Delta)
Vaccines and Drugs
Herpes Simplex Virus
Background
Diagnostic Tests
Vaccines and Drugs
Legionella
Background
Diagnostic Tests
Vaccines and Drugs
Lyme Disease
Background
Clinical Description
Clinical Case Definition
Laboratory Criteria for Diagnosis
Case Classification
Diagnostic Tests
Vaccines and Drugs
Malaria
Mycoplasma
Background
Ureaplasma Urealyticum & Mycoplasma Hominis
Diagnostic Tests
Vaccines and Drugs
Papillomaviruses/HPV
Background
HPV in Cancer
Cervical Neoplasm
Diagnostic Tests
Vaccines and Drugs
Prevention
Parvovirus B19
Background
Microbiology
Epidemiology
Clinical Syndromes
Erythema Infectiosum (Slapped Cheek)
Adult Polyarthropathy
Transient Aplastic Crisis
Transient Pancytopenia
Red Cell Aplasia in Immunocompromised
Perinatal Infections
Diagnostic Test
Vaccines and Drugs
Pneumonia
Background
Diagnostic Tests
Vaccines and Drugs
Polyomaviruses
Background
Diagnostic Tests
Vaccines and Drugs
Salmonellosis
Background
Diagnostic Tests
Vaccines and Drugs
Shigellosis
Background
Diagnostic Tests
Vaccines and Drugs
Streptococci
Background
Diagnostic Tests
Vaccines and Drugs
Group A Streptococci
Group B Streptococci
Toxoplasmosis
Background
Diagnostic Tests
Vaccines and Drugs
Tuberculosis
Background
Diagnostic Tests
Microscopic Characteristics
Cultural Characteristics
Skin Tests
MDRTB
Vaccines and Drugs
West Nile Virus
Background
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
Yersinia
Background
Diagnostic Tests
Vaccines and Drugs
Antibiotic Susceptibility Cancer Testing
a. Overview
b. Major Cancer Types
Prostate
Lung
Colon and Rectum
Breast
Skin
Uterine
Leukemia
Oral
c. Oncogenes
Abl/abl-bcr
AIB1
BCL-2
BRCA1
CD44
C-fos
C-myb
C-myc
CYP17
Erb-B
HPC1
N-myc
P40
P51
P53
PIK3CA
PTI-1
Ras
Reg
Sis
Src
GENETIC DISEASES
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
Achondroplasia
Autosomal Dominant Polycystic Kidney Disease
Cancer
Cosmetogenomics
Cystic Fibrosis
Down's Syndrome
Duchenne and Becker Muscular Dystrophy
Factor V (Leiden)
Factor IX Deficiency
Fragile X Syndrome
Heart Disease
Hemochomatosis
Hemophilia
Huntington's Disease
Maternal-Fetal Incompatibility
Multiple Endocrine Neoplasia
Phenylketonuria (PKU)
Polycystic Kidney Disease (PKD)
Prenatal Screening
Retinitis Pigmentosa
Retinoblastoma
Sickle Cell Anemia
Spinal Muscular Atrophy
Vitamin B12 Metabolism
i. Social Issues and Concerns
FORENSIC TESTING
a. Overview
b. Multilocus and Single Locus Probes
Multilocus Probes
Single Locus Probes
PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
U.S.A.
U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing t-the DNA Probe Market Expansion
Technology Availability
Use of Hair as Evidence
h. Wildlife Forensics
PATERNITY TESTING/HLA TYPING
OTHER APPLICATIONS
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
COMPETITIVE PROFILES
Abbott
Affymetrix
Agilent
Applied Gene Technologies
Arca
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
Bio-Rad
Biotest
Caliper
Cepheid
Decode
Diadexus
Eiken
Enzo
Exact Sciences
Fujirebio
Gen-Probe
Hologic
Illumina
Innogenetics/Solvay
Kreatech
Li-Cor Biosciences
Life Technologies
Monogram Biosciences
Myriad Genetics
Nanogen/Elitech
Novartis
Orchid CellMark
Ortho-Clinical Diagnostics
Proteome Sciences
Qiagen
Roche
Scienion
Sequenom
Shimadzu
Siemens
Sierra Molecular
Takara Bio
Tecan Group
a. Overview
b. Major Infectious Diseases
AIDS
Structure and Composition
Classification
AIDS Origins
Animal Lentivirus Systems
Virus Receptors
HIV Infections in Humans
Pathogenesis and Pathology
CD4T Lymphocytes and Memory Cells
Monocytes and Macrophages
Lymphoid Organs
Neural Cells
Viral Coinfections
Clinical Findings
Plasma Viral Load
Pediatric AIDS
Neurologic Disease
Opportunistic Infections
Cancer
Immunity
Virus Isolation
Serology
Viral Nucleic Acid/Antigen Detection
Epidemiology
Worldwide Spread of AIDS
United States
Routes of Transmission
DNA Probes
Overview
Quantitative PCR
In Situ PCR
Needed Improvements
Viral Load/Drug Resistance Testing
Genotype and Phenotype Testing
Blood Banking Considerations
Adenovirus
Background
Diagnostic Tests
Vaccines and Drugs
Adeno-Associated Viruses (AAV)
Anthrax/Bacillus Anthracis
Background
Diagnostic Tests
Vaccines and Drugs
Babesiosis
Background
BEA and Other Bartonella Diseases
Background
Diagnostic Tests
Vaccines and Drugs
Chagas Disease
Background
Campylobacter
Background
Diagnostic Tests
Culture Identification
Vaccines and Drugs
Chlamydia
Background
Chlamydia psittaci
Chlmaydia pneumoniae
Chlamydia trachomatis
Diagnostic Tests
Vaccines and Drugs
Creutzfeldt-Jakob’s Disease
Background
Blood Transmission
Diagnostic Tests
Major Commercial and Academic Players
Bayer
Disease Sciences/Bi-Tec Global
Imperial College School of Medicine
Ortho-Clinical Diagnostics
Pall
ProMetic Life Sciences
Proteome Sciences/Idexx
Q-One Biotech
Serono
U.S. Agricultural Research Service
Drugs
Vaccines
Cytomegalovirus
Background
Chorioretinitis
Gastrointestinal
Central Nervous System Disease
Diagnostic Tests
Vaccines and Drugs
Ebola Virus
Background
Epidemiology
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
EchoVirus
Background
Acute Aseptic Meningitisis
Encephalitis
Exanthems
Respiratory Disease
Myopericarditis
Neonatal Infections
Diagnostic Tests
Vaccines and Drugs
Encephalitis
Background
Diagnostic Tests
Vaccines and Drugs
Enteroviruses
Background
Diagnostic Tests
Viral Isolation and Identification
Antibody Tests
Vaccines and Drugs
Epstein-Barr Virus
Background
Diagnostic Tests
Vaccines and Drugs
Gonorrhea
Background
Diagnostic Tests
Vaccines and Drugs
Hepatitis
Hepatitis A
Hepatitis B
Structure and Composition
Replication
Hepatitis C
Hepatitis D (Delta)
Hepatitis E
Hepatitis G
Hepatitis Infections Pathology
Clinical Findings
Laboratory Tests
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Virus-Host Immune Reactions
Epidemiology
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D (Delta)
Vaccines and Drugs
Herpes Simplex Virus
Background
Diagnostic Tests
Vaccines and Drugs
Legionella
Background
Diagnostic Tests
Vaccines and Drugs
Lyme Disease
Background
Clinical Description
Clinical Case Definition
Laboratory Criteria for Diagnosis
Case Classification
Diagnostic Tests
Vaccines and Drugs
Malaria
Mycoplasma
Background
Ureaplasma Urealyticum & Mycoplasma Hominis
Diagnostic Tests
Vaccines and Drugs
Papillomaviruses/HPV
Background
HPV in Cancer
Cervical Neoplasm
Diagnostic Tests
Vaccines and Drugs
Prevention
Parvovirus B19
Background
Microbiology
Epidemiology
Clinical Syndromes
Erythema Infectiosum (Slapped Cheek)
Adult Polyarthropathy
Transient Aplastic Crisis
Transient Pancytopenia
Red Cell Aplasia in Immunocompromised
Perinatal Infections
Diagnostic Test
Vaccines and Drugs
Pneumonia
Background
Diagnostic Tests
Vaccines and Drugs
Polyomaviruses
Background
Diagnostic Tests
Vaccines and Drugs
Salmonellosis
Background
Diagnostic Tests
Vaccines and Drugs
Shigellosis
Background
Diagnostic Tests
Vaccines and Drugs
Streptococci
Background
Diagnostic Tests
Vaccines and Drugs
Group A Streptococci
Group B Streptococci
Toxoplasmosis
Background
Diagnostic Tests
Vaccines and Drugs
Tuberculosis
Background
Diagnostic Tests
Microscopic Characteristics
Cultural Characteristics
Skin Tests
MDRTB
Vaccines and Drugs
West Nile Virus
Background
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
Yersinia
Background
Diagnostic Tests
Vaccines and Drugs
Antibiotic Susceptibility Cancer Testing
a. Overview
b. Major Cancer Types
Prostate
Lung
Colon and Rectum
Breast
Skin
Uterine
Leukemia
Oral
c. Oncogenes
Abl/abl-bcr
AIB1
BCL-2
BRCA1
CD44
C-fos
C-myb
C-myc
CYP17
Erb-B
HPC1
N-myc
P40
P51
P53
PIK3CA
PTI-1
Ras
Reg
Sis
Src
GENETIC DISEASES
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
Achondroplasia
Autosomal Dominant Polycystic Kidney Disease
Cancer
Cosmetogenomics
Cystic Fibrosis
Down's Syndrome
Duchenne and Becker Muscular Dystrophy
Factor V (Leiden)
Factor IX Deficiency
Fragile X Syndrome
Heart Disease
Hemochomatosis
Hemophilia
Huntington's Disease
Maternal-Fetal Incompatibility
Multiple Endocrine Neoplasia
Phenylketonuria (PKU)
Polycystic Kidney Disease (PKD)
Prenatal Screening
Retinitis Pigmentosa
Retinoblastoma
Sickle Cell Anemia
Spinal Muscular Atrophy
Vitamin B12 Metabolism
i. Social Issues and Concerns
FORENSIC TESTING
a. Overview
b. Multilocus and Single Locus Probes
Multilocus Probes
Single Locus Probes
PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
U.S.A.
U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing t-the DNA Probe Market Expansion
Technology Availability
Use of Hair as Evidence
h. Wildlife Forensics
PATERNITY TESTING/HLA TYPING
OTHER APPLICATIONS
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
COMPETITIVE PROFILES
Abbott
Affymetrix
Agilent
Applied Gene Technologies
Arca
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
Bio-Rad
Biotest
Caliper
Cepheid
Decode
Diadexus
Eiken
Enzo
Exact Sciences
Fujirebio
Gen-Probe
Hologic
Illumina
Innogenetics/Solvay
Kreatech
Li-Cor Biosciences
Life Technologies
Monogram Biosciences
Myriad Genetics
Nanogen/Elitech
Novartis
Orchid CellMark
Ortho-Clinical Diagnostics
Proteome Sciences
Qiagen
Roche
Scienion
Sequenom
Shimadzu
Siemens
Sierra Molecular
Takara Bio
Tecan Group
LIST OF FIGURES
Major Companies Developing or Marketing AIDS Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Herpes
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Legionella
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Lyme
Disease Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Papilloma
Virus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Shigella
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis
Molecular Diagnostic And Other Direct Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer
Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular
Diagnostic Test For Genetic Diseases
Major Companies Developing or Marketing AIDS Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Herpes
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Legionella
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Lyme
Disease Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Papilloma
Virus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Shigella
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis
Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis
Molecular Diagnostic And Other Direct Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer
Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular
Diagnostic Test For Genetic Diseases
