World Pain Relieving Drug Market 2013-2023

Date: July 24, 2013
Pages: 257
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Publisher: Visiongain
Report type: Strategic Report
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ID: W5C0C508213EN
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World Pain Relieving Drug Market 2013-2023
New study reveals sales potential of this large, expanding market

See what the future holds for painkillers. Visiongain's report gives you revenue predictions to 2023. You find data, trends, opportunities and commercial prospects.

That new study lets you assess forecasted sales at overall world market, submarket, product and national level. You see why the pain relievers industry and market will grow, as we predict.

In our investigation you find revenue forecasting, growth rates and market shares. Also, you see qualitative analyses, R&D and commercial developments. You receive 84 tables, 79 charts and three research interviews.

The following sections highlight what you discover in the report.

Prospects for submarkets and products

In addition to analyses of the overall world market, you see revenue forecasting of five world-level submarkets to 2023:
  • Narcotics
  • Non-narcotics
  • Neuropathic pain relievers
  • Treatments for migraines
  • Treatments for arthritis.
Also, you see how 29 leading drugs - including Oxycontin ER, Panadol, Lyrica and Zomig - can perform to 2023. Our study includes OTC (over-the-counter) and Rx (prescription) pain relieving medicines. There, you find revenue forecasts and other data.
The work also breaks the overall world market into leading national markets.

Prospects for leading countries shown to 2023

Developments worldwide will influence the market, especially fast-rising demand in emerging countries. There will be many opportunities for pain-treating products.

You discover revenue forecasts to 2023 for twelve national markets:
  • US
  • Japan
  • Germany, France, UK, Italy and Spain (EU5 nations)
  • India
  • China
  • Brazil
  • Russia
  • Turkey
This decade, revenues from India and China will be among the fastest growing worldwide. In particular, product launches from 2013 onwards will benefit regional and national markets.

Research and development activities

What's happening in the R&D pipeline for painkillers? You see developmental trends there:
  • Narcotic drugs
  • Non-narcotic products
  • Neuropathic treatments
  • Anti-migraine agents
  • Arthritic pain relievers.
Discover how technological progress changes the sector. Our investigation explains, bringing together many issues.

Prominent issues affecting the pain treatment sector

Our study lets you assess industry trends and outlooks worldwide from 2013. As the work shows, many issues affect the industry and market:
  • Better treatment of acute and chronic pain worldwide, including cancer pain
  • Anticonvulsants, analgesics, COX-2 inhibitors, novel opioids, cannabinoids and local anaesthetics
  • Non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids and aldose reductase inhibitors
  • Disease modifying anti-rheumatic drugs (DMARDs)
  • Biologics (e.g. monoclonal antibodies, MAbs) for rheumatoid arthritis (RA)
  • Reimbursement, regulations, patent expiries, generic competition and OTC switching.
You see discussions of technological, commercial and economic matters, with emphasis on organisations competing in the industry.

Discussions of leading companies and prospects for market growth

What will happen next? The pharmaceutical industry will improve treatments for pain relief and increase revenues there from 2013 to 2023. The R&D pipeline is strong.

Overall world revenue for that market area will reach $68.0bn in 2013, our report forecasts. Ageing populations and diseases such as cancer, arthritis and diabetes will increase sales of painkillers. Also, improved drug delivery and new formulations will be important.

You find discussions of Pfizer, GSK, Johnson & Johnson, Bristol-Myers Squibb and other developers and manufacturers. This decade, many opportunities will arise.

Eight ways World Pain Relieving Drug Market 2013-2023 benefits you

In particular, then, our study gives you the following knowledge on painkilling drugs:
  • Forecasted revenues to 2023 for the overall world market and submarkets
  • Potential revenues of 29 leading products to 2023
  • Market forecasting to 2023 for the US, Japan, leading EU countries (Germany, France, the UK, Italy and Spain), India, China, Brazil, Russia and Turkey
  • Assessment of companies - discussions of activities and outlooks
  • Review of R&D pipelines by treatment area - progress and trends
  • Opinions on the sector, including our research interviews with leaders in industry
  • Investigation of competition and opportunities influencing sales
  • Discussion of what stimulates and restrains the industry and market.
That work gives independent analyses from our primary and secondary research. You receive information found only in our report.

With our study, you find business intelligence to help you understand the future of that industry and market.

Ordering now lets you discover prospects for drugs treating pain

Visiongain's study is for everybody needing commercial analyses for the treatment of pain. You find data, trends and predictions there. Please order that report now.
1. EXECUTIVE SUMMARY

1.1 The Pain Relieving Drug Market: Overview
1.2 Aims, Scope and Format of the Report
1.3 Research and Analysis Methods

2. INTRODUCTION TO THE PAIN RELIEVING DRUG MARKET

2.1 What is Pain?
  2.1.1 Historical Aspects of Pain
2.2 Pain Pathways and the Origin of Pain
  2.2.1 WHO Pain Ladder
2.3 Classification and Types of Pain
  2.3.1 Acute Pain
  2.3.2 Chronic Pain
  2.3.3 Psychosocial Effects of Chronic Pain
  2.3.4 Chronic Cancer Pain
  2.3.5 Breakthrough Cancer Pain
2.4 Neuropathic Pain
  2.4.1 Distinguishing Neuropathic Pain
2.5 Neurochemistry of Pain
  2.5.1 Prostaglandins
  2.5.2 Opioids
2.6 Treatment
  2.6.1 Opioids in the Treatment of Pain
2.7 OTC Pain Relievers

3. THE WORLD PAIN RELIEVING DRUG MARKET, 2013-2023

3.1 The World Pain Relieving Drug Market: Analysis and Forecast, 2013-2023
3.2 Submarket Categories of the World Pain Drug Market
  3.2.1 Anti-Arthritic Drug Sales Will Continue to Dominate
  3.2.2 Neuropathic Pain Market Will Grow
3.3 Success in the World Pain Treatment Market Has Been Challenging
3.4 The Pain Relieving Drug Market Will Expand

4. NARCOTIC PAIN RELIEVING DRUGS: WORLD MARKET ANALYSIS AND FORECAST, 2013-2023

4.1 Oxycontin ER (Purdue Pharma): Market Analysis and Forecast, 2013-2023
  4.1.1 Launch of Tamper Resistant Oxycontin ER
  4.1.2 Patent and Legal Battles of Oxycontin ER
  4.1.3 Oxycontin ER Sales Forecast, 2013-2023
4.2 Opana ER (Endo Pharmaceuticals): Market Analysis and Forecast, 2013-2023
  4.2.1 Development of Tamper Resistant Opana ER
  4.2.2 Opana ER Sales Forecast, 2013-2023
4.3 Duragesic (Johnson & Johnson): Market Analysis and Forecast, 2013-2023
  4.3.1 Duragesic Sales Forecast, 2013-2023
4.4 Ultram (Johnson & Johnson, Ortho-McNeil): Market Analysis and Forecast, 2013-2023
4.5 Zaldiar/Ultracet (GrГјnenthal): Market Analysis and Forecast, 2013-2023
4.6 World Market Forecast for Other Narcotic Drugs, 2013-2023

5. NON-NARCOTIC PAIN RELIEVING DRUGS: WORLD MARKET ANALYSIS AND FORECAST, 2013-2023

5.1 Advil (Pfizer): Market Analysis and Forecast, 2013-2023
  5.1.1 Development of Advil (Ibuprofen)
  5.1.2 Advil Sales Forecast, 2013-2023
5.2 Panadol (GSK): Market Analysis and Forecast, 2013-2023
  5.2.1 Panadol Sales Forecast, 2013-2023
5.3 Bayer Aspirin (Bayer): Market Analysis and Forecast, 2013-2023
  5.3.1 Development of Bayer Aspirin (Acetylsalicyclic Acid)
  5.3.2 Bayer Aspirin Sales Forecast, 2013-2023
5.4 Efferalgan (Bristol-Myers Squibb): Market Analysis and Forecast, 2013-2023
5.5 Tylenol (Johnson & Johnson, Ortho-McNeil): Market Analysis and Forecast, 2013-2023
  5.5.1 Eroded Sales in 2012
  5.5.2 Tylenol Sales Forecast, 2013-2023
5.6 Other Non-Narcotic Pain Relieving Drugs: Market Analysis and Forecast, 2013-2023

6. NEUROPATHIC PAIN RELIEVING DRUGS: WORLD MARKET ANALYSIS AND FORECAST, 2013-2023

6.1 Treatment Options
6.2 Pharmacological Treatments
  6.2.1 Anti-Convulsants
  6.2.2 Analgesics
  6.2.3 Local Anaesthetics
  6.2.4 Anti-Depressants
  6.2.5 Aldose Reductase Inhibitors
6.3 World Neuropathic Pain Relieving Drug Sales Forecast, 2013-2023
6.4 Lyrica (Pfizer): Market Analysis and Forecast, 2013-2023
  6.4.1 Impact of Lyrica Patent Expiry
6.5 Cymbalta (Eli Lilly): Market Analysis and Forecast, 2013-2023
6.6 Lidoderm (Endo Pharmaceuticals): World Market Analysis and Forecast, 2013-2023
  6.6.1 Impact of Lidoderm Patent Expiry
6.7 Neurontin Market Forecast, 2013-2023
6.8 Nucynta Franchise (GrГјnenthal GmbH, Johnson & Johnson): Market Analysis and Forecast, 2013-2023
  6.8.1 Development of Nucynta ER (Tapentadol)
  6.8.2 Nucynta Franchise Sales Forecast, 2013-2023
  6.8.3 Nucynta Franchise Has High Potential
6.9 Qutenza (NeurogesX) and NGX-1998 Market Prospects
6.10 Kinedak (Ono Pharmaceuticals) Market Prospects
6.11 Development and Market Prospects of Horizant (Xenoport, GSK)
6.12 Will Gralise (Depomed) Become a Market Leader?
6.13 Future Treatment of Neuropathies
  6.13.1 Therapies That Can Target the Underlying Cause Are in Demand

7. ANTI-MIGRAINE DRUGS: WORLD MARKET ANALYSIS AND FORECAST, 2013- 2023

7.1 How is Migraine Treated and Prevented?
  7.1.1 Migraine Treatment
  7.1.2 Migraine Prevention
7.2 World Anti-Migraine Drug Sales Forecast, 2013-2023
7.3 Maxalt (Merck & Co.): Market Analysis and Forecast, 2013-2023
7.4 Zomig (AstraZeneca): Market Analysis and Forecast, 2013-2023
7.5 Relpax (Pfizer): Market Analysis and Forecast, 2013-2023
7.6 Imitrex/Imigran (GSK): Market Analysis and Forecast, 2013-2023
7.7 Botox (Allergan): Market Analysis and Forecast, 2013-2023
  7.7.1 Botox Will Boost World Migraine Sales
7.8 Axert (Johnson & Johnson, Almirall): Market Analysis and Forecast, 2013-2023
7.9 Treximet (GSK, Pozen): Market Analysis and Forecast, 2013-2023
7.10 What Does the Future Hold for Migraine Therapy?
7.11 Unmet Needs in the Treatment of Migraine

8. ANTI-ARTHRITIC PAIN DRUGS: WORLD MARKET ANALYSIS AND FORECAST, 2013-2023

8.1 Arthritis
8.2 What Drugs are used to Treat Arthritis?
  8.2.1 Pain Relieving Drugs and Analgesics
  8.2.2 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  8.2.3 Corticosteroids
  8.2.4 Disease Modifying Anti-Rheumatic Drugs (DMARDs)
  8.2.5 Biologics
8.3 Biologics for Rheumatoid Arthritis Treatment
  8.3.1 Side Effects of Biologics
8.4 World Anti-Arthritic Pain Drug Sales Forecast, 2013-2023
8.5 Humira (Abbott Laboratories): Market Analysis and Forecast, 2013-2023
  8.5.1 Long-Term Prospects for Humira
8.6 Enbrel (Amgen, Pfizer, Takeda): Market Analysis and Forecast, 2013-2023
  8.6.1 Amgen Continues to Benefit from Enbrel Sales
  8.6.2 Enbrel Sales Will Show an Initial Increase
  8.6.3 Study Eases Fears of TNF Blocker Cancer Risk
  8.6.4 New Enbrel Delivery System
  8.6.5 Sales of Enbrel will Eventually Decline
  8.6.6 Enbrel Faces Competition from Several Other Biotech Drugs
8.7 Remicade (Johnson & Johnson): Market Analysis and Forecast, 2013-2023
  8.7.1 Long Term Prospects for Remicade
8.8 Rituxan (MabThera-Roche; Biogen Idec): Market Analysis and Forecast, 2013-2023
  8.8.1 Rituxan is a Leading Biosimilar Target
8.9 Celebrex (Pfizer): Market Analysis and Forecast, 2013-2023
  8.9.1 Development of Celebrex
  8.9.2 Celebrex Sales Forecast, 2013-2023
8.10 Voltaren (Endo, Novartis): Market Analysis and Forecast, 2013-2023
  8.10.1 Voltaren Sales Forecast, 2013-2023
8.11 Arcoxia (Merck & Co.): Market Analysis and Forecast, 2013-2023
  8.11.1 Development of Arcoxia
  8.11.2 Arcoxia Sales Forecast, 2013-2023
8.12 Outlook for the Anti-Arthritic Pain Drug Market

9. LEADING NATIONAL MARKETS FOR PAIN RELIEVING DRUGS, 2013-2023

9.1 The Pain Relieving Drug Market: Regional Sales Breakdown
9.2 Pain Drug Revenues in Leading National Markets, 2013-2023
  9.2.1 The Pain Relieving Drug Market in the US, 2013-2023
  9.2.2 The Pain Relieving Drug Market in Japan, 2013-2023
  9.2.3 Top 5 EU Markets for Pain Relieving Drugs, 2013-2023
  9.2.4 The Pain Relieving Drug Market in Germany, 2013-2023
  9.2.5 The Pain Relieving Drug Market in France, 2013-2023
  9.2.6 The Pain Relieving Drug Market in the UK, 2013-2023
  9.2.7 The Pain Relieving Drug Market in Italy, 2013-2023
  9.2.8 The Pain Relieving Drug Market in Spain, 2013-2023
9.3 Emerging Economies Showing Strong Performance, 2013-2023
  9.3.1 The Pain Relieving Drug Market in China, 2013-2023
  9.3.2 The Pain Relieving Drug Market in Brazil, 2013-2023
  9.3.3 The Pain Relieving Drug Market in Russia, 2013-2023
  9.3.4 The Pain Relieving Drug Market in India, 2013-2023
  9.3.5 The Pain Relieving Drug Market in Turkey, 2013-2023
9.4 The Pain Relieving Drug Market in the Rest of the World, 2013-2023

10. THE R&D PIPELINE FOR THE TREATMENT OF PAIN, 2013

10.1 The R&D Pipeline for Pain Drugs is Large and Expanding
10.2 The Potential of the Pain Market Has Encouraged R&D
10.3 Innovation Rules for Early Stage Pipeline Drugs
10.4 Narcotic Pain Relieving Drug Pipeline, 2013
  10.4.1 Acurox (Acura, Pfizer)
  10.4.2 Remoxy (Pfizer, Pain Therapeutics, Durect)
  10.4.3 BEMA Buprenorphine (BioDelivery Sciences, Endo Pharmaceuticals)
  10.4.4 Morphine Glucuronide (Paion)
  10.4.5 MoxDuo IR (Shire; China Aoxing; QRxPharma)
  10.4.6 Acuracet (Pfizer, Acura)
  10.4.7 ARX 02 (AcelRx Pharmaceuticals)
  10.4.8 Zohydro ER (Zogenix)
  10.4.9 COL-003 (Collegium)
  10.4.10 ALO 02 (Pfizer)
  10.4.11 Subsys (Insys Therapeutics)
  10.4.12 Oxceta (Pfizer, Acura)
10.5 Non-Narcotic Pain Relieving Drug Pipeline, 2013
  10.5.1 Exparel (Pacira Pharmaceuticals)
  10.5.2 Lofexidine HCl (US WorldMeds)
  10.5.3 Synera (Nuvo Research)
  10.5.4 Neosaxitoxin (Proteus SA)
  10.5.5 Adlea (ALRGX-4975) (Anesiva, Johns Hopkins University)
  10.5.6 OMS 103 HP (Omeros)
  10.5.7 Tetrodotoxin (WEX, CK Life Sciences)
  10.5.8 CE 224535 (Pfizer)
  10.5.9 MK-2295 (Ligand, Merck & Co.)
10.6 Neuropathic Pain Relieving Drug Pipeline, 2013
  10.6.1 Retigabine (Valeant, GSK)
  10.6.2 Perampanel (Eisai)
  10.6.3 Serenbotase (Syntaxin, Allergan)
  10.6.4 EMA401 (Spinifex)
  10.6.5 KRN5500 (Dara Biosciences)
  10.6.6 NT-11624 (Neurotune)
  10.6.7 ARC-2022 (Arcion)
  10.6.8 ARC-4558 (Arcion)
  10.6.9 Amiket (EpiCept)
  10.6.10 Ralfinamide (Newron)
  10.6.11 Eladur (Durect)
  10.6.12 AVP-923 (Avanir Pharmaceuticals)
10.7 Anti-Migraine Drug Pipeline, 2013
  10.7.1 Zelrix (NuPathe)
  10.7.2 BMS-927711 (Bristol-Myers Squibb)
  10.7.3 Lasmiditan (CoLucid Pharmaceuticals)
  10.7.4 Telcagepant (Merck & Co.)
  10.7.5 NXN-188 (NeurAxon)
  10.7.6 BGG492 (Novartis)
  10.7.7 LY2300559 (Eli Lilly)
10.8 Anti-Arthritic Pain Drug Pipeline, 2013
  10.8.1 Duexa (Horizon Pharma)
  10.8.2 Zavryl/Ibuprofen-PC (PLx Pharma)
  10.8.3 Naproxcinod (NicOx)
  10.8.4 Lodotra/RAYOS Horizon Pharma, SkyePharma)
  10.8.5 Tofacitinib (Pfizer)
  10.8.6 Ofatumumab (Genmab, GSK)
  10.8.7 Mastinitib (AB Science)
  10.8.8 Belimumab (GSK, Human Genome Sciences)
10.9 The Future of Pain Research
  10.9.1 Advanced Drug Delivery
    10.9.1.1 Delivery of Low Solubility Drugs
  10.9.2 Challenges Faced by Novel Painkillers - Monoclonal Antibodies (MAbs)
  10.9.3 Novel Opioid Molecules
10.10 Cannabinoids and Pain

11. DRIVERS AND RESTRAINTS IN THE WORLDWIDE PAIN RELIEVING DRUG MARKET, 2013-2023

11.1 STEP/SWOT Analysis of the World Pain Relieving Drug Market, 2013-2023
11.2 Social, Technological, Economic and Political Factors Affecting the Pain Relieving Drug Market (STEP Analysis), 2013-2023
  11.2.1 Social Factors Influencing the Pain Relieving Drug Market
  11.2.2 Technological Factors Influencing the Pain Relieving Drug Market
  11.2.3 Economic Factors Influencing the Pain Relieving Drug Market
  11.2.4 Political Factors Influencing the Pain Relieving Drug Market
11.3 Market Drivers
11.4 Market Restraints
11.5 The Pain Market after the Withdrawal of COX-2 Inhibitors
11.6 Lack of Adequate Reimbursement Limits Potential of Pain Drugs
11.7 Reformulations of Existing Drugs Will Drive Market Growth
11.8 Narcotics Market Will Continue to Grow Despite Reported Concerns of Side Effects
11.9 Risk of Intestinal Bleeding Associated With Use of NSAIDs
11.10 Ageing Population
11.11 Patent Expiries Will Lead to Generic Competition
11.12 OTC Switching
11.13 Education in Pain Management is a Key Unmet Need
  11.13.1 Personalised Pain Management Therapy

12. RESEARCH INTERVIEWS FROM OUR SURVEY

12.1 Interview with Dr Bradley S. Galer, MD, President of Pain Group, Nuvo Research Inc.
  12.1.1 Perspective on the Pain Treatment Market
  12.1.2 Challenges in the Pain Treatment Market
  12.1.3 Insight on the Topical Pain Relief Market
  12.1.4 Thoughts on Arthritic Pain Market Developments
  12.1.5 Thoughts on Key Submarkets
  12.1.6 Views on Drivers and Threats
  12.1.7 Treatments in the R&D Pipeline
  12.1.8 Future of World Pain Treatment Market
12.2 Interview with Dr John Andrews, President and Chief Scientific Officer, NeurAxon.
  12.2.1 Perspective on the Pain Treatment Market
  12.2.2 Key Unmet Needs
  12.2.3 Thoughts on Key Submarkets
  12.2.4 Development of the Anti-Migraine Drug Market
  12.2.5 Views on Drivers and Threats
  12.2.6 Thoughts on National Market Opportunities
  12.2.7 Treatments in the R&D Pipeline
  12.2.8 Views on the Future of the Market
12.3 Interview with Dr Tuulikki Sokka, MD, PhD, Head of Rheumatology, Jyväskylä Central Hospital, Finland.
  12.3.1 On Current and Future Anti-arthritic Treatments
  12.3.2 On Unmet Needs in the Anti-arthritic Sector
  12.3.3 On the R&D Pipeline for Rheumatoid Arthritis
  12.3.4 On Drivers of the Anti-arthritic Therapy Sector
  12.3.5 On Global Prevalence of Rheumatoid Arthritis

13. CONCLUSIONS

13.1 The Pain Drug Market Will Achieve Revenue Growth from 2013
13.2 Narcotics Submarket Will Grow Despite Reported Concerns
13.3 Strong Growth Expected in Neuropathic and Cancer Pain Submarkets
13.4 Botox Approval Expected to Boost Anti-Migraine Submarket
13.5 The Anti-Arthritic Pain Drug Submarket Will Remain Strong
13.6 Leading National Markets Will Achieve Revenue Growth
13.7 The Worldwide Pain Drug Treatment Market Holds Strong Potential from 2013 to 2023

LIST OF FIGURES

Figure 2.1 Pain Categories
Figure 3.1 World Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 3.2 World Pain Relieving Drug Market: Market Shares (%) by Submarkets, 2012
Figure 3.3 World Pain Relieving Drug Market: Market Shares (%) by Submarkets, 2017
Figure 3.4 World Pain Relieving Drug Market: Market Shares (%) by Submarkets, 2023
Figure 4.1 World Narcotic Pain Relieving Drugs Market: Sales Forecast ($m), 2012-2023
Figure 4.2 World Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2012
Figure 4.3 World Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2017
Figure 4.4 World Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2023
Figure 4.5 World Oxycontin ER Sales Forecast ($m), 2012-2023
Figure 4.6 World Opana ER Sales Forecast ($m), 2012-2023
Figure 4.7 World Duragesic Sales Forecast ($m), 2012-2023
Figure 4.8 World Ultram ER Sales Forecast ($m), 2012-2023
Figure 4.9 World Zaldiar/Ixprim Sales Forecast ($m), 2012-2023
Figure 4.10 World Other Narcotic Drug Sales Forecast ($m), 2012-2023
Figure 5.1 World Non-Narcotic Pain Relieving Drugs Market: Sales Forecast ($m), 2012-2023
Figure 5.2 World Non-Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2012
Figure 5.3 World Non-Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2017
Figure 5.4 World Non-Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2023
Figure 5.5 World Advil Sales Forecast ($m), 2012-2023
Figure 5.6 World Panadol Sales Forecast ($m), 2012-2023
Figure 5.7 World Bayer Aspirin Sales Forecast ($m), 2012-2023
Figure 5.8 World Efferalgan Sales Forecast ($m), 2012-2023
Figure 5.9 World Tylenol Sales Forecast ($m), 2012-2023
Figure 5.10 World Other Non-Narcotic Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 6.1 World Neuropathic Pain Relieving Drugs Market: Sales Forecast ($m), 2012-2023
Figure 6.2 Rising Prevalence of Diabetes, 2011, 2030 & 2050
Figure 6.3 World Neuropathic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2012
Figure 6.4 World Neuropathic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2017
Figure 6.5 World Neuropathic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs, 2023
Figure 6.6 World Lyrica Sales Forecast ($m), 2012-2023
Figure 6.7 World Cymbalta Sales Forecast ($m), 2012-2023
Figure 6.8 World Lidoderm Sales Forecast ($m), 2012-2023
Figure 6.9 World Neurontin Sales Forecast ($m), 2012-2023
Figure 6.10 World Nucynta Franchise Sales Forecast ($m), 2012-2023
Figure 7.1 World Anti-Migraine Drugs Market: Sales Forecast ($m), 2012-2023
Figure 7.2 World Anti-Migraine Drug Market: Market Shares (%) of Leading Drugs, 2012
Figure 7.3 World Anti-Migraine Drug Market: Market Shares (%) of Leading Drugs, 2017
Figure 7.4 World Anti-Migraine Drug Market: Market Shares (%) of Leading Drugs, 2023
Figure 7.5 World Maxalt Sales Forecast ($m), 2012-2023
Figure 7.6 World Zomig Sales Forecast ($m), 2012-2023
Figure 7.7 World Relpax Sales Forecast ($m), 2012-2023
Figure 7.8 World Imitrex/Imigran Sales Forecast ($m), 2012-2023
Figure 7.9 World Botox Sales Forecast ($m), 2012-2023
Figure 7.10 World Axert Sales Forecast ($m), 2012-2023
Figure 7.11 World Treximet Sales Forecast ($m), 2012-2023
Figure 8.1 World Anti-Arthritic Drugs Market: Sales Forecast ($m), 2012-2023
Figure 8.2 World Anti-Arthritic Drug Market: Market Shares (%) of Leading Drugs, 2012
Figure 8.3 World Anti-Arthritic Drug Market: Market Shares (%) of Leading Drugs, 2017
Figure 8.4 World Anti-Arthritic Drug Market: Market Shares (%) of Leading Drugs, 2023
Figure 8.5 World Humira Sales Forecast ($m), 2012-2023
Figure 8.6 World Enbrel Sales Forecast ($m), 2012-2023
Figure 8.7 World Remicade Sales Forecast ($m), 2012-2023
Figure 8.8 World Rituxan Sales Forecast ($m), 2012-2023
Figure 8.9 World Celebrex Sales Forecast ($m), 2012-2023
Figure 8.10 World Voltaren Sales Forecast ($m), 2012-2023
Figure 8.11 World Arcoxia Sales Forecast ($m), 2012-2023
Figure 9.1 US, Japan & Total World: Pain Relieving Drug Sales Forecasts ($m), 2012-2023
Figure 9.2 Leading European Markets: Pain Relieving Drug Sales Forecasts ($m), 2012-2023
Figure 9.3 Leading Asian and Emerging Markets: Pain Relieving Drug Sales Forecasts ($m), 2012-2023
Figure 9.4 Pain Relieving Drug Market Shares (%) in Leading National Markets, 2012
Figure 9.5 Pain Relieving Drug Market Shares (%) in Leading National Markets, 2017
Figure 9.6 Pain Relieving Drug Market Shares (%) in Leading National Markets, 2023
Figure 9.7 US: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.8 Japan: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.9 Germany: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.10 France: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.11 UK: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.12 Italy: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.13 Spain: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.14 China: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.15 Brazil: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.16 Russia: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.17 India: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.18 Turkey: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 9.19 Rest of The World: Pain Relieving Drug Sales Forecast ($m), 2012-2023
Figure 11.1 World Population Forecast, 2012-2023
Figure 11.2 World Population Aged 65 and Over: Forecast, 2012-2023
Figure 11.3 Population Aged 65 and Over in Seven Leading Developed Pain Drug Markets, 2012 & 2023

COMPANIES LISTED

AB Science
Abbott Laboratories
AcelRx Pharmaceuticals
Actavis
Acura Pharmaceuticals
Allergan
Almirall
Alpharma
ALZA Corporation
American Academy of Pain Medicine
American Council for Headache Education
Amgen
Anesiva
Aoxing Pharmaceuticals
Apotec.
Apotex.
Arcion Therapeutics
Astellas Pharma
AstraZeneca
Australian New Zealand Clinical Trials Registry (ANZCTR)
Avanir Pharmaceuticals
Bayer
BioDelivery Sciences
Biogen Idec
Biovail Corporation
Boston Millennia Partners
Bristol-Myers Squibb
Britannia Pharmaceuticals
CeNeS Pharmaceuticals
Centocor Ortho Biotech
China Aoxing
CK Life Sciences
Collegium Pharmaceutical
CoLucid Pharmaceuticals
Dainippon
Dara Biosciences
Depomed
Descartes Therapeutics
Dr. Reddy's Laboratories
Durect
Eisai
Eli Lilly
Endo Pharmaceuticals
EpiCept
Eurocept BV
European Medicines Agency (EMA)
Food and Drug Administration (FDA)
Forest Pharmaceuticals
Frazier Healthcare Ventures
Galderma
Genentech
Genmab
GlaxoSmithKline (GSK)
GrГјnenthal
Horizon Pharma
Human Genome Sciences
Insys Therapeutics
International Association for the Study of Pain
Ipsen
IVAX Pharmaceuticals
Janssen Pharmaceuticals
Johns Hopkins University
Johnson and Johnson (J&J)
Jyväskylä Central Hospital
King Pharmaceuticals
Ligand Pharmaceuticals
Longitude Capital
Lundbeck
MAP Pharmaceuticals
Merck & Co.
Merck Serono
Mitsubishi Tanabe Pharma
Mundipharma
Mylan
National Cancer Institute (NCI)
National Health Service (NHS)
National Institute for Health and Clinical Excellence (NICE UK)
Nektar Therapeutics
NeurAxon
NeurogesX
Neurotune
Newron Pharmaceuticals
NicOx Pharmaceuticals
Novartis
NuPathe
Nuvo Research
Omeros
Ono Pharmaceutical
Organon
Ortho-McNeil
Pacira Pharmaceuticals
Pain Therapeutics
Paion
Paladin
Par Pharmaceuticals
Penwest
Pfizer
Pharmacia
PLx Pharma
Pozen
PriCara Pharmaceuticals
Procter & Gamble
Proteus
Purdue Pharma
QRxPharma
Ranbaxy
Ratiopharm
Rigel Pharmaceuticals
Roche
Sanofi
Schering Plough
Shire
SkyePharma
Skyline Ventures
Solvay Pharmaceuticals
Spinifex Pharmaceuticals
Stada Pharmaceuticals
Sun Pharmaceuticals
Syntaxin
Takeda
Teikoku
Teva Pharmaceutical Industries
The Arthritis Foundation
The International Diabetes Federation (IDF)
The Neuropathy Association
The World Health Organization (WHO)
UCB
University of Queensland
US Census Bureau
US Society for Neuroscience
US WorldMeds
Valeant Pharmaceuticals International
Watson Pharmaceuticals
WEX Pharmaceuticals
Wyeth (now part of Pfizer)
Xenoport
Zars Pharmaceuticals
Zenyaku Kogyo
Zogenix

Botox (Allergan): Market Analysis and Forecast, 2013-2023

Botox (onabotulinumtoxinA) is a protein and neurotoxin produced by the bacterium clostridium botulinum. Botox is manufactured by Allergan Inc., and is used for cosmetic and therapeutic purposes. Therapeutic uses include the treatment of certain neuromuscular disorders, hyperhydrosis, prophylactic treatment of headaches in adults with chronic migraine and urinary incontinence.

Botox was first approved by the US FDA in 1989 for the treatment of two eye muscle disorders, strabismus and blepharospasm, making it the first botulinum toxin type A product approved in the world. Since its first approval, Botox has been approved by regulatory authorities worldwide as a treatment for approximately 25 unique indications in approximately 85 countries. Botox was first approved for certain aesthetic uses in 2002.

Since the FDA's approval of Dysport, a competing product, the FDA has required that all botulinum toxins marketed in the US include a boxed warning regarding the symptoms associated with the spread of botulinum toxin beyond the injection site along with a corresponding risk evaluation and mitigation strategies (REMS). However, apparently there has not been a confirmed case of spread of toxin effect when Botox has been used at the recommended dose to treat chronic migraine, reports also indicate.

Botox Will Boost World Migraine Sales

In 2012, total global sales of Botox reached $1,767m, a rise of 13% over the previous year. Therapeutic sales accounted for 52% of the total global sales figures in 2012. In October 2010 Botox became a first in class drug when it was approved for prophylaxis of headaches in adults with chronic migraine. Botox is now approved for the prophylactic treatment of adult chronic migraine in approximately 25 countries, including the UK and almost all other countries in the European Union as well as Australia, Brazil, Canada, India and Korea. Visiongain estimates that chronic migraine treatment with Botox generated $260m sales in 2012. In May 2012 Allergan announced that the National Institute for Health and Clinical Excellence (NICE) is recommending Botox for the prophylaxis (prevention) of headache in adults with chronic migraine, highlighting the confidence that Botox treatment has generated since FDA approval in 2010.

Visiongain's Botox sales forecast only includes sales attributed to migraine treatment. Visiongain believes that Botox sales for migraine will increase steadily through the entire forecast period. Generic competition is not expected in the first half of the forecast period, as Botox is a biologic drug and the uptake of biosimilar products in the US is expected to be slow. Visiongain believes that the launch of Botox as a chronic migraine treatment has promoted awareness of new treatment options among people having migraines, therefore helping to drive the overall growth of the anti-migraine market as undiagnosed patients demand treatments. Visiongain believes that migraine revenues for Botox will rise steadily over the first half of the forecast period, reaching $425m by 2017, representing a CAGR of 10.4% for the forecast period 2012-2017. Sales will continue to grow at a slower rate towards the end of the forecast period, owing to competition from other biologics being introduced to the market. By 2023 sales will reach $533m, representing a CAGR of 6.8% for the entire forecast period 2012-2023.

The material was prepared in September, 2013.

LIST OF TABLES

Table 2.1 Defining Acute and Chronic Pain
Table 3.1 World Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 3.2 World Pain Relieving Drug Sales Forecasts ($m), AGRs (%), CAGRs (%) for Submarkets, 2012-2017
Table 3.3 World Pain Relieving Drug Sales Forecasts ($m), AGRs (%), CAGRs (%) for Submarkets, 2018-2023
Table 3.4 World Pain Relieving Drug Market: Market Shares (%) by Submarkets in 2012, 2017 & 2023
Table 4.1 World Narcotic Pain Relieving Drugs Market: Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 4.2 Leading Narcotic Pain Relieving Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2012-2017
Table 4.3 Leading Narcotic Pain Relieving Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2018-2023
Table 4.4 World Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs in 2012, 2017 & 2023
Table 4.5 World Oxycontin ER Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 4.6 World Opana ER Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 4.7 World Duragesic Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 4.8 World Ultram ER Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 4.9 World Zaldiar/Ixprim Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 4.10 World Other Narcotic Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.1 World Non-Narcotic Pain Relieving Drugs Market: Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.2 Leading Non-Narcotic Pain Relieving Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2012-2017
Table 5.3 Leading Non-Narcotic Pain Relieving Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2018-2023
Table 5.4 World Non-Narcotic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs in 2012, 2017 & 2023
Table 5.5 Advil North American Formulations, 2013
Table 5.6 World Advil Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.7 Panadol Formulations, 2013
Table 5.8 World Panadol Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.9 World Bayer Aspirin Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.10 World Efferalgan Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.11 Tylenol Products, 2013
Table 5.12 World Tylenol Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 5.13 World Other Non-Narcotic Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.1 Key Drugs Indicated for Neuropathic Pain, 2013
Table 6.2 FDA-Approved Drugs Indicated for Neuropathic Pain, 2013
Table 6.3 World Neuropathic Pain Relieving Drugs Market: Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.4 Rising Prevalence of Diabetes, 2011, 2030 & 2050
Table 6.5 Leading Neuropathic Pain Relieving Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.6 World Neuropathic Pain Relieving Drug Market: Market Shares (%) of Leading Drugs in 2012, 2017 & 2023
Table 6.7 World Lyrica Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.8 World Cymbalta Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.9 World Lidoderm Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.10 World Neurontin Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 6.11 World Nucynta Franchise Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.1 World Anti-Migraine Drugs Market: Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.2 Leading Anti-Migraine Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.3 World Anti-Migraine Drug Market: Market Shares (%) of Leading Drugs in 2012, 2017 & 2023
Table 7.4 World Maxalt Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.5 World Zomig Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.6 World Relpax Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.7 World Imitrex/Imigran Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.8 World Botox Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.9 World Axert Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 7.10 World Treximet Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.1 Examples of Anti-Arthritic Pain Drugs, 2013
Table 8.2 World Anti-Arthritic Drugs Market: Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.3 World Anti-Arthritic Drugs Market: Market Shares (%) of Leading Drugs in 2012, 2017 & 2023
Table 8.4 Leading Anti-Arthritic Drugs: Sales Forecasts ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.5 World Humira Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.6 World Enbrel Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.7 World Remicade Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.8 World Rituxan Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.9 World Celebrex Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.10 World Voltaren Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 8.11 World Arcoxia Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.1 Pain Relieving Drug Sales Forecasts ($m), AGRs (%), CAGRs (%) for Leading National Markets, 2012-2017
Table 9.2 Pain Relieving Drug Sales Forecasts ($m), AGRs (%), CAGRs (%) for Leading National Markets, 2018-2023
Table 9.3 Pain Relieving Drug Market Shares (%) in Leading National Markets, 2012, 2017 & 2023
Table 9.4 US: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.5 Japan: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.6 Germany: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.7 France: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.8 UK: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGR (%), 2012-2023
Table 9.9 Italy: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.10 Spain: Pain Relieving Drugs Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.11 China: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.12 Brazil: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.13 Russia: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.14 India: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.15 Turkey: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 9.16 Rest of the World: Pain Relieving Drug Sales Forecast ($m), AGRs (%), CAGRs (%), 2012-2023
Table 10.1 R&D Pipeline for Narcotic Pain Drugs, 2013
Table 10.2 R&D Pipeline for Non-Narcotic Pain Drugs, 2013
Table 10.3 R&D Pipeline for Neuropathic Pain Drugs, 2013
Table 10.4 R&D Pipeline for Anti-Migraine Pain Drugs, 2013
Table 10.5 R&D Pipeline for Anti-Arthritic Pain Drugs, 2013
Table 11.1 STEP Analysis of the Pain Relieving Drug Market, 2013-2023
Table 11.2 SWOT Analysis of the Pain Relieving Drug Market, 2013-2023
Table 11.3 World Population Forecast, 2012-2023

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Global Pain Relieving Drug Market Analysis 2010-2025 US$ 2,325.00 Apr, 2010 · 150 pages
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