Synthetic Biology: Market Research Report

January 2015 | 240 pages | ID: S05E57DEDACEN
Global Industry Analysts, Inc

Abstracts

This report analyzes the worldwide markets for Synthetic Biology in US$ Thousands by the following Product Segments: Enabled Products, and Others. The report also analyzes the market by the following Application Areas: Energy and Chemicals, Biotechnology and Pharmaceuticals, and Others. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 51 companies including many key and niche players such as -

• Amyris, Inc.
• BP PLC
• Chromatin Inc.
• Evolva SA
• Gevo, Inc.

Contents

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study

II. EXECUTIVE SUMMARY

1. OUTLOOK

A Quick Primer
Synthetic Biology: Prediction Becoming Reality
Current and Future Analysis
Analysis by Region
Analysis by Product Segment
Analysis by End-Use Market
Key Growth Drivers and Major Concerns
Growth Drivers
Major Concerns
Future Outlook

2. INDUSTRY OVERVIEW

Synthetic Biology – An Emerging Discipline in Need of Promotion
Contribution of Synthetic Biology to Biotech
Craig Venter’s Synthetic Life: Momentous Achievement in Synthetic Biology Field
Gibson Assembly: Building Toolset for Synthetic Biology
Gen9’s BioFab: Major Breakthrough in Synthetic Biology
Key Developments in the Synthetic Biology Field: A Synopsis
Synthetic Biology Products with Commercial Potential in the Future by End Market
Competitive Landscape
Competition in Synthetic Biology Market
Intrexon: Leader in Synthetic Biology Field
Key Factors Contributing to Intrexon’s Success in Synthetic Biology Field
Proprietary Suite of Innovative Technologies
Unique ECC-based Business Model
A Synopsis of Intrexon’s ECC Agreements: 2011-2013

3. MARKET TRENDS, DRIVERS, AND ISSUES

Is Synthetic Biology a Bane or Boon?
Synthetic Biology Exhibits Plateau in Awareness
Synthetic Biology Research Gathers Momentum
US and Europe - Propelling Research in the Field of Synthetic Biology

Table 1. Number of Entities Focused on Synthetic Biology Research Globally: 2009 & 2013 (includes corresponding Graph/Chart)

Table 2. Synthetic Biology and their Potential Areas of Applications Being Researched by Biological Systems Manufacturers/Designers (includes corresponding Graph/Chart)

Table 3. Number of Biological Systems Manufacturers/Designers Focused on Specialty/Fine Chemical Applications (includes corresponding Graph/Chart)

Table 4. Number of Patent Filings Related to Synthetic Biology: 2003-2013 (includes corresponding Graph/Chart)

Table 5. Leading Filers of Patent Applications Related to Synthetic Biology: 2003-2013 (includes corresponding Graph/Chart)

Synthetic Biology Mired by Challenges in Developing Countries
Synthetic Biology Bringing a Paradigm Shift in the Field of Biological Research
DNA Sequencing Technique Propelling Growth for Synthetic Biology
Plummeting Cost of DNA Sequencing Bolsters Market Growth

Table 6. Cost per Genome Sequencing: 2001-2014

Systems Biology Leading to Advancements in Synthetic Biology
Synthetic Biology based Microbial Factories for Production of Poppies
Food and Other Basic Needs’ Scarcity to Fuel Synthetic Biology Market
Food, Water, and Energy Statistics

Table 7. Top 20 Countries Worldwide in Terms of Population in Million (2014) (includes corresponding Graph/Chart)

Will Synthetic Biology Mitigate Food Security Concerns?
Growing Demand for GM Crops Opens Up Growth Avenues
Synthetic Biology-based Ingredients Gain Traction
Role of Synthetic Biology in Producing Plants with Desirable Characteristics
Do-It-Yourself Biology (DIYBio): A Growing Phenomenon
Synthetic Biology Ingredients in Consumer Products - Laden with Concerns
Synthetic Biology Gaining Prominence in Biomedical Applications
Research Efforts in Full Swing to Treat Life-Threatening Diseases using Synthetic Biology
Synthetic Biology Therapeutics to Address Antibiotic-Resistance Crisis
Pipeline Perspective of Synthetic Biology Therapeutics (Synthetic Biologics and Intrexon Collaboration)
Synthetic Biology for Wildlife Conservation Laden with Risks
Synthetic Biology Enabling Creation of Advanced Biosensing Systems
Synthetic Biology Gains Significance in Production of Bio-Based Chemicals and Biofuels
Contribution of Synthetic Biology to Renewable Chemicals
Synthetic Biology for Energy Supply: Potential Threat to Biodiversity
SynBio Products and Ingredients Face Opposition from Several Organizations
Lack of Regulatory Framework - A Major Concern

4. KEY RESEARCH FINDINGS ON SYNTHETIC BIOLOGY

Biologists Implants Artificial Chromosome in Yeast to Create Artificial Life
Synthetic Genes to Open New World of Drug Development
Researchers Announce Production of Peptoid Nanosheets
Synthetic Biology in Repelling Viruses
Synthetic Biology in Engineered Food
Synthetic Biology to Address Issues Related to Algal Blooms
Synthetic Biology Holds Potential for Testing Water Purity
Mars – A Home Away from Home Courtesy Synthetic Biology
Predictable Biological Systems - No More a Myth
Researchers at JCVI Make Novel Advances in Synthetic Genomics
Synthetic Biology Tools Can Detect Listeria Contamination in Food Products
Synthetic Biology Accelerates Flu Vaccine Production
Bioengineers at Duke University Develops Novel System for Reproducing Natural Complex Gene Regulation
TALE: A Viable Technology for Synthetic Protein Development
Can Synthetic Biology Fuel Cars or Household Power Supplies Using Naturally-Existing Fatty Acids?
Researchers Engineered Synthetic Compound to Defend Iron Deficiency
Cellular Circuit Designing Made Possible through Biological Genes
Meshing Inputs/Outputs Offer Layered Circuits
Cambrian Genomics Pioneers DNA Laser Printer
Researchers Develop Novel Technique that Speeds the Process for Developing New Biological Parts
Researchers Develop Novel Biological Device that Mimics Transistor-Like Properties

5. SYNTHETIC BIOLOGY - AN OVERVIEW

Introduction
Historical Background
Synthetic Biology Vis-à-vis Genetic Engineering - A Comparison
Scope of Synthetic Biology in Various Fields
Engineering
Chemistry
Major Enabling Technologies
Sequencing
Fabrication
Modeling
Measurement
Synthetic Biology Market – By Product
Core Products/Biologic Components
Synthetic Genes
Synthetic Cells
Chassis Organisms
Escherichia coli
Bacillus subtilis
Yeast
Mycoplasma
Acinetobacter
Mycoplasma genitalium
XNA (Xeno Nucleic Acid)
Enabling Products
DNA Synthesis
Oligonucleotide Synthesis
Market Potential
Pharmaceutical
Industrial
Agriculture
Life Sciences Research
Renewable Energy
Synthetic Biology Applications/Products with Highest Potential for Commercialization by 2030
Potential Uses
Biomedicine
Intricate Molecular Devices Utilized for Tissue Regeneration/Repair
Smart Drugs
Biological Delivery Systems
Vectors for Therapy
Personalized Medicine
Cells with Novel Properties for Betterment of Human Health
In Vivo Synthesis of Small-Molecule Pharmaceuticals
Intricate Natural Products
Expansion of Chemistry of Life
Expanding Genetic Alphabet
Nucleic Acids
Proteins
New Imaging and Targeting Methods
Chemical Industry Sustainability
Eco-friendly Production of Chemicals
Energy and Environment
Bioremediation
Energy Production
Biomaterials and Smart Materials Production
Synthesis
Organization
Socio-Economic Concerns and Risks of Synthetic Biology
Production of Bio-Weapons
Accidental Release
Return on Investment
Dissonance with Other Disciplines
Continuous Evolution
Curtailed Understanding
Unpredictable Ecosystem Effects
Unexpected Transfer of Genes
Aggravating Problems
Industry Associations
Synthetic Biology Industry Association (SynBIA)
Industry Association of Synthetic Biology (IASB)

6. PRODUCT INNOVATIONS/INTRODUCTIONS

Synthetic Biologics Obtains Orphan Drug Designation for SYN-005 mAb
Agilent Technologies Introduces SureGuide Kits
Agilent Technologies Rolls Out ClearSeq AML Next-Generation Sequencing Cancer Research Panels
Gen9 Rolls Out Variant Libraries
Gen9 Introduces GeneByte Plus DNA Constructs
Agilent Technologies Introduces SureSelect Clinical Research Exome
Agilent Technologies Launches QuikChange HT Protein Engineering Synthetic Biology System
GenScript Introduces GenEZ Next-Generation Molecular Cloning Service
DNA2. 0 Releases CRISPR/Cas9 Tools for Genome Editing and Engineering
GenScript Unveils GenPlus Next-Generation Gene Synthesis Technology
Life Technologies Introduces new GeneArt Algae Protein Expression Kits
Life Technologies Unveils Vector NTI Express Designer Bioinformatics Software Platform
Gen9 Introduces GeneBytes DNA Constructs
New England Biolabs and Synthetic Genomics Launches Gibson Assembly Cloning Kit and NEBuilder Primer Design Tool
GenScript Introduces Gene-Brick Gene Synthesis Service

7. RECENT INDUSTRY ACTIVITY

Genome Compiler Enters into Collaborative Agreement with DNA2.
Eurofins Genomics Enters into Co-operation Agreement with Igenbio
Bacterial Robotics Signs Strategic Agreement with Bacmine
Intrexon and Histogenics Enter into Exclusive Channel Collaboration for Cartilage Repair Therapies
Intrexon and Amneal Pharmaceuticals Announce Second Exclusive Channel Collaboration for a Target API
Synthetic Biologics and FUJIFILM Diosynth Biotechnologies Announces Positive Phase I Outcomes of API Manufacturing of SYN-004
Evolva Holding Acquires Prosarix
Igenbio Collaborates with Genome Compiler
Pareto Biotechnologies Enters into Technology Partnership with DNA2.
Roche Enters into Research Agreement with Stratos Genomics
Cellectis Enters into Agreement with Thermo Fisher Scientific
Roche Acquires Genia Technologies
Synthorx, a New Synthetic Biotechnology Company Launches
Synthetic Genomics Enters into Long-Term R&D Agreement with Lung Biotechnology
OriGene Introduces Genome-wide Gene-knockout Kits
Intrexon Concludes Acquisition of Medistem
Amyris Enters into Collaborative R&D Agreement with BASF
MIT SBC Collaborates with Pfizer
Tauriga Sciences Acquires Pilus Energy LLC
OvaScience and Intrexon Enter into Agreement
Sanofi Commences Large-Scale Production of Semi-Synthetic Artemisinin
EVOLVA and IFF Enter into Pre-Manufacturing Phase for Natural Vanillin
Synthetic Genomics Enters into Research Agreement with ExxonMobil
Amyris Signs Long Term Agreement with International Flavors & Fragrances
SGI-DNA and IDT Announce Expanded Collaboration
College of Engineering Establishes BU Center of Synthetic Biology
Gen9 Enters into Partnership with Agilent Technologies
AquaBounty Technologies Enters into Exclusive Channel Collaboration with Intrexon
Synthetic Biologics Collaborates with Intrexon for Infectious Disease Therapies
DuPont Collaborates with OligoCo
DNA2. 0 Collaborates with Newcastle University
Amyris Secures Contract from the US DARPA
Pfenex Collaborates with DNA2.
Synthetic Genomics Inks Agreement with New England Biolabs
Amyris Commences Production of Biofene in Brazil

8. FOCUS ON SELECT PLAYERS

Players Focused on Synthetic Biology Applications
Amyris, Inc. (US)

BP PLC. (UK)

Chromatin Inc. (US)
Evolva SA (Switzerland)
Gevo, Inc. (US)
Joule Unlimited, Inc. (US)
Metabolix (US)
MorphoSys AG (Germany)
Sapphire Energy, Inc. (US)
Solazyme, Inc. (US)
Synthetic Biologics, Inc. (US)
Synthetic Genomics, Inc. (US)
Players Focused on Gene Synthesis and Tools

454 LIFE SCIENCES (US)

Agilent Technologies Inc. (US)
ATG Biosynthetics GmbH (Germany)

DNA2. 0 (US)

Epoch Life Science, Inc. (US)
Gen9, Inc. (US)
GenScript USA, Inc. (US)
Gingko Bioworks, Inc. (US)
Intrexon Corporation (US)
LC Sciences LLC (US)
Life Technologies Corp. (US)
OPXBIO, Inc. (US)
OriGene Technologies, Inc. (US)
Sangamo BioSciences, Inc. (US)
Verdezyne, Inc. (US)

9. GLOBAL MARKET PERSPECTIVE

Table 8. World Recent Past, Current & Future Analysis for Synthetic Biology by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 9. World Historic Review for Synthetic Biology by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

Table 10. World 14-Year Perspective for Synthetic Biology by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)

Table 11. World Recent Past, Current & Future Analysis for Synthetic Biology by Product Segment - Enabled Products and Others Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 12. World Historic Review for Synthetic Biology by Product Segment - Enabled Products and Others Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

Table 13. World 14-Year Perspective for Synthetic Biology by Product Segment - Percentage Breakdown of Dollar Sales for Enabled Products and Others Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)

Table 14. World Recent Past, Current & Future Analysis for Synthetic Biology by End-Use Sector - Energy & Chemicals, Biotechnology & Pharmaceuticals, and Others Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 15. World Historic Review for Synthetic Biology by End-Use Sector - Energy & Chemicals, Biotechnology & Pharmaceuticals, and Others Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

Table 16. World 14-Year Perspective for Synthetic Biology by End-Use Sector - Percentage Breakdown of Dollar Sales for Energy & Chemicals, Biotechnology & Pharmaceuticals, and Others Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)

III. MARKET

1. THE UNITED STATES

A. Market Analysis
Current & Future Analysis
Research in the US

Table 17. Number of Entities Focused on Synthetic Biology Research in the US (2009 & 2013) (includes corresponding Graph/Chart)

International Genetically Engineered Machine (IGEM) – A Platform for Innovations
Product Launches
Strategic Corporate Developments
Key Players
B. Market Analytics

Table 18. US Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 19. US Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

2. CANADA

Market Analysis

Table 20. Canadian Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 21. Canadian Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

3. JAPAN

Market Analysis

Table 22. Japanese Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 23. Japanese Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

4. EUROPE

A. Market Analysis
Current & Future Analysis
Research in Europe

Table 24. Number of Entities Focused on Synthetic Biology Research in Europe (2009 & 2013) (includes corresponding Graph/Chart)

Table 25. Number of Entities Focused on Synthetic Biology Research by Area of Interest: 2013 (includes corresponding Graph/Chart)

B. Market Analytics

Table 26. European Recent Past, Current & Future Analysis for Synthetic Biology by Geographic Region - France, Germany, Italy, UK, Spain and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 27. European Historic Review for Synthetic Biology by Geographic Region - France, Germany, Italy, UK, Spain and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

Table 28. European 14-Year Perspective for Synthetic Biology by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK, Spain and Rest of Europe Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)

4A. FRANCE

A. Market Analysis
Current & Future Analysis
Strategic Corporate Development
B. Market Analytics

Table 29. French Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 30. French Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

4B. GERMANY

A. Market Analysis
Current & Future Analysis
Key Players
B. Market Analytics

Table 31. German Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 32. German Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

4C. ITALY

Market Analysis

Table 33. Italian Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through 2020 (includes corresponding Graph/Chart)

Table 34. Italian Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

4D. THE UNITED KINGDOM

A. Market Analysis
Current & Future Analysis
Market Overview
UK Government Awards Over £6 Million Grant for Synthetic Biology
UK Government Funding for Synthetic Biology: 2013
Synbicite Centre to Spearhead UK Research In Synthetic Biology
UK Sets Up New Synthetic Biology Research Centers
Synthetic Biology Research Centre Nottingham (Sbrc Nottingham)
Bristol Centre for Synthetic Biology (Brissynbio)
Openplant Synthetic Biology Research Centre
University of Edinburgh inks Agreement with Bgi to Develop Artificial Yeast Genome
Strategic Corporate Development
BP Plc. - A Key Player
B. Market Analytics

Table 35. UK Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 36. UK Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

4E. SPAIN

A. Market Analysis
Current & Future Analysis
Strategic Corporate Development
B. Market Analytics

Table 37. Spanish Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through 2020 (includes corresponding Graph/Chart)

Table 38. Spanish Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

4F. REST OF EUROPE

A. Market Analysis
Current & Future Analysis
Evolva SA (Switzerland) – A Major Player
B. Market Analytics

Table 39. Rest of Europe Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 40. Rest of Europe Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

5. ASIA-PACIFIC

A. Market Analysis
Current & Future Analysis

Table 41. Number of Entities Focused on Synthetic Biology Research in Asia and Oceania in 2013 (includes corresponding Graph/Chart)

B. Market Analytics

Table 42. Asia-Pacific Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 43. Asia-Pacific Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

6. REST OF WORLD

A. Market Analysis
Current & Future Analysis
Strategic Corporate Development
B. Market Analytics

Table 44. Rest of World Recent Past, Current & Future Analysis for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)

Table 45. Rest of World Historic Review for Synthetic Biology Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 51 (including Divisions/Subsidiaries - 52)
The United States (41)
Canada (1)
Europe (8)
  France (1)
  Germany (3)
  The United Kingdom (1)
  Spain (1)
  Rest of Europe (2)
Asia-Pacific (Excluding Japan) (2)