Cell Surface Markers: US, Europe, Japan Forecasts by Test, Market Segment and Country

August 2011 | 120 pages | ID: C2FD15A873BEN
Venture Planning Group

Abstracts

The report provides a worldwide overview of the cell surface marker testing, including 5-year forecasts for CD4, CD8, CD34 and other markers by country.

Rationale

The use of surface marker identification and classification of cells began with the revolution in immunology brought about by the discovery of T and B cells, which can be distinguished by virtue of specific surface markers. The technology has now spread to the subclassification of lymphocytes, and has begun to allow the identification of many other cell types, such as monocytes, macrophages, myeloid stem cells, and tumor cells.

The devices are now available to detect single cells that are capable of making antibody against a particular antigen, and to sort those cells into separate culture vessels. This permits the screening and cloning of cells in one operation, while automatically weeding out the dead cells in the process. A combination of the hybridoma technology with flow cytometry is synergistic, and will further expand the applications of both technologies.

During the next five years, the main trend in flow cytometry in general, and in cell surface marker analysis specifically, will be further simplification of the sample preparation and the analysis itself. Contains 120 pages and 15 tables

Contents

I. INTRODUCTION

II. WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW

A. Lymphocyte Subclassification CD4/CD8/CD34
  Instrumentation and Reagent Test Kits
    BD FACS Count
    Beckman Coulter VCS
    T Cells Diagnostics TRAx
B. Other Cell Markers
C. Instrumentation Review
  1. Hematology Analyzers
    a. Overview
      Electrical Aperture-Impedance Analyzers
      Light Scatter Analyzers
    b. System Review
      Abbott Cell-Dyn 3000
      Abbott Cell-Dyn 3200
      Abbott Cell-Dyn 3500
      Abbott Cell-Dyn 3700
      Abbott Cell-Dyn Ruby
      Abbott Cell-Dyn Sapphire
      Abbott Cell-Dyn Emerald
      Beckman Coulter HmX
      Beckman Coulter LH 500
      Beckman Coulter LH 750
      Beckman Coulter LH 780
      Beckman Coulter LH 1500
      Beckman Coulter STKS
      Beckman Coulter UniCell DxH 800
      Horiba ABX Helios LMG/5DIFF
      Horiba ABX Pentra Series
      Siemens ADVIA/H Series
      Siemens Advia 120
      Siemens Advia 2120i
      Sysmex XE-2100
      Sysmex XE-5000
      Sysmex XE-AlphaN
      Sysmex HST-N
      Sysmex NE-8000
      Sysmex SE-9000
      Sysmex XT Series
  2. Flow Cytometers
    a. Introduction
    b. System Overview
      Beckman Coulter Epics Profile
      Beckman Coulter Epics XL
      BD FACSadvantage
      BD FACSAria III
      BD FACScan
      BD FACSCanto II
      BD FACSCalibur
      BD FACSCount
      BD Influx
      BD FACStar Series
      BD FACSort
      BD FACStrak
      BD FACS Vantage
      Beckman Coulter Epics Elite ESP
      Beckman Coulter Epics Elite Analyzer
      Beckman Coulter Epics C
      Beckman Coulter FC 500 Series
      Beckman Coulter Vi-CELL XR
D. Current Market Needs and Future Demand for Hematology Analyzers
E. Reagents and Controls
F. Current and Emerging Technologies
  1. Information Technologies
  2. Automation and Robotics
  3. Lasers
  4. Artificial Intelligence
  5. Monoclonal Antibodies
  6. Molecular Diagnostics
  7. Microdrop Technology

III. FRANCE : FORECASTS BY TEST AND MARKET SEGMENT

IV. GERMANY : FORECASTS BY TEST AND MARKET SEGMENT

V. ITALY : FORECASTS BY TEST AND MARKET SEGMENT

VI. JAPAN : FORECASTS BY TEST AND MARKET SEGMENT

VII. SPAIN : FORECASTS BY TEST AND MARKET SEGMENT

VIII. U.K. : FORECASTS BY TEST AND MARKET SEGMENT

IX. U.S. : FORECASTS BY TEST AND MARKET SEGMENT

X. ALTERNATIVE MARKET PENETRATION STRATEGIES

A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies for the Decentralized Testing Markets
  1. Four Marketing Approaches
  2. Product Complexity Factor
  3. Customer Preference Factor
  4. Established Suppliers
  5. Emerging Suppliers
  6. Major Types of Distributors
  7. Market Segmentation Factor

XI. POTENTIAL MARKET ENTRY BARRIERS AND RISKS

A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

XII. COMPETITIVE ASSESSMENTS

      Abbott
      Beckman Coulter
      Becton Dickinson
      Bio-Rad
      DakoCytomation
      Horiba
      Iris
      J&J Diagnostics
      Nihon Kohden
      Roche
      Siemens
      Sysmex

XIII. APPENDIX: MAJOR UNIVERSITIES AND RESEARCH CENTERS DEVELOPING HEMATOLOGY/FLOW CYTOMETRY TECHNOLOGIES AND APPLICATIONS

List Of Tables

LIST OF TABLES

France, Hospital Laboratories Estimated Cell Surface Marker Test Volume
France, Commercial/Private Laboratories Estimated Cell Surface Marker Test Volume
Germany, Hospital Laboratories Estimated Cell Surface Marker Test Volume
Italy, Hospital Laboratories Estimated Cell Surface Marker Test Volume
Italy, Commercial/Private Laboratories Estimated Cell Surface Marker Test Volume
Japan, Hospital Laboratories Estimated Cell Surface Marker Test Volume
Japan, Commercial/Private Laboratories Estimated Cell Surface Marker Test Volume
Spain, Hospital Laboratories Estimated Cell Surface Marker Test Volume
Spain, Commercial/Private Laboratories Estimated Cell Surface Marker Test Volume
Spain, Ambulatory Care Center Estimated Cell Surface Marker Test Volume
U.K., Hospital Laboratories Estimated Cell Surface Marker Test Volume
U.K., Commercial/Private Laboratories Estimated Cell Surface Marker Test Volume
U.S., Hospital Laboratories Estimated Cell Surface Marker Test Volume
U.S., Commercial/Private Laboratories Estimated Cell Surface Marker Test Volume
U.S., Physician Office Laboratories Estimated Cell Surface Marker Test Volume