Global Tangential Flow Filtration Sales Market Report to 2021

October 2016 | 129 pages | ID: G3C89F27B6CEN
QYResearch

Abstracts

Notes:

Sales, means the sales volume of Tangential Flow Filtration

Revenue, means the sales value of Tangential Flow Filtration

This report studies sales (consumption) of Tangential Flow Filtration in Global market, especially in USA, China, Europe, Japan, India and Southeast Asia, focuses on top players in these regions/countries, with sales, price, revenue and market share for each player in these regions, covering

• Danaher Corporation (U.S.)
• Merck Millipore (U.S.)
• Sartorius Stedim Biotech S.A. (France)
• Parker Hannifin Corporation (U.S.)
• GE Healthcare (U.S.)
• Alfa Laval AB (Sweden)
• Spectrum Laboratories (U.S.)
• Novasep (U.S.)

Market Segment by Regions, this report splits Global into several key Regions, with sales (consumption), revenue, market share and growth rate of Tangential Flow Filtration in these regions, from 2011 to 2021 (forecast), like

• USA
• China
• Europe
• Japan
• India
• Southeast Asia

Split by product Types, with sales, revenue, price and gross margin, market share and growth rate of each type, can be divided into

• Single-use Systems
• Reusable Systems
• Membrane Filters
• Filtration Accessories

Split by applications, this report focuses on sales, market share and growth rate of Tangential Flow Filtration in each application, can be divided into

• Bioprocessing
• Viral Vectors and Vaccine Purification
• Pharmaceutical Water Production
• Other Applications?

Contents

Global Tangential Flow Filtration Sales Market Report 2016

1 TANGENTIAL FLOW FILTRATION OVERVIEW

1.1 Product Overview and Scope of Tangential Flow Filtration
1.2 Classification of Tangential Flow Filtration
  1.2.1 Single-use Systems
  1.2.2 Reusable Systems
  1.2.3 Membrane Filters
  1.2.4 Filtration Accessories
1.3 Application of Tangential Flow Filtration
  1.3.1 Bioprocessing
  1.3.2 Viral Vectors and Vaccine Purification
  1.3.3 Pharmaceutical Water Production
  1.3.4 Other Applications?
1.4 Tangential Flow Filtration Market by Regions
  1.4.1 USA Status and Prospect (2011-2021)
  1.4.2 China Status and Prospect (2011-2021)
  1.4.3 Europe Status and Prospect (2011-2021)
  1.4.4 Japan Status and Prospect (2011-2021)
  1.4.5 India Status and Prospect (2011-2021)
  1.4.6 Southeast Asia Status and Prospect (2011-2021)
1.5 Global Market Size (Value and Volume) of Tangential Flow Filtration (2011-2021)
  1.5.1 Global Tangential Flow Filtration Sales and Growth Rate (2011-2021)
  1.5.2 Global Tangential Flow Filtration Revenue and Growth Rate (2011-2021)

2 GLOBAL TANGENTIAL FLOW FILTRATION COMPETITION BY MANUFACTURERS, TYPE AND APPLICATION

2.1 Global Tangential Flow Filtration Market Competition by Manufacturers
  2.1.1 Global Tangential Flow Filtration Sales and Market Share of Key Manufacturers (2011-2016)
  2.1.2 Global Tangential Flow Filtration Revenue and Share by Manufacturers (2011-2016)
2.2 Global Tangential Flow Filtration (Volume and Value) by Type
  2.2.1 Global Tangential Flow Filtration Sales and Market Share by Type (2011-2016)
  2.2.2 Global Tangential Flow Filtration Revenue and Market Share by Type (2011-2016)
2.3 Global Tangential Flow Filtration (Volume and Value) by Regions
  2.3.1 Global Tangential Flow Filtration Sales and Market Share by Regions (2011-2016)
  2.3.2 Global Tangential Flow Filtration Revenue and Market Share by Regions (2011-2016)
2.4 Global Tangential Flow Filtration (Volume) by Application

3 USA TANGENTIAL FLOW FILTRATION (VOLUME, VALUE AND SALES PRICE)

3.1 USA Tangential Flow Filtration Sales and Value (2011-2016)
  3.1.1 USA Tangential Flow Filtration Sales and Growth Rate (2011-2016)
  3.1.2 USA Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
  3.1.3 USA Tangential Flow Filtration Sales Price Trend (2011-2016)
3.2 USA Tangential Flow Filtration Sales and Market Share by Manufacturers
3.3 USA Tangential Flow Filtration Sales and Market Share by Type
3.4 USA Tangential Flow Filtration Sales and Market Share by Application

4 CHINA TANGENTIAL FLOW FILTRATION (VOLUME, VALUE AND SALES PRICE)

4.1 China Tangential Flow Filtration Sales and Value (2011-2016)
  4.1.1 China Tangential Flow Filtration Sales and Growth Rate (2011-2016)
  4.1.2 China Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
  4.1.3 China Tangential Flow Filtration Sales Price Trend (2011-2016)
4.2 China Tangential Flow Filtration Sales and Market Share by Manufacturers
4.3 China Tangential Flow Filtration Sales and Market Share by Type
4.4 China Tangential Flow Filtration Sales and Market Share by Application

5 EUROPE TANGENTIAL FLOW FILTRATION (VOLUME, VALUE AND SALES PRICE)

5.1 Europe Tangential Flow Filtration Sales and Value (2011-2016)
  5.1.1 Europe Tangential Flow Filtration Sales and Growth Rate (2011-2016)
  5.1.2 Europe Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
  5.1.3 Europe Tangential Flow Filtration Sales Price Trend (2011-2016)
5.2 Europe Tangential Flow Filtration Sales and Market Share by Manufacturers
5.3 Europe Tangential Flow Filtration Sales and Market Share by Type
5.4 Europe Tangential Flow Filtration Sales and Market Share by Application

6 JAPAN TANGENTIAL FLOW FILTRATION (VOLUME, VALUE AND SALES PRICE)

6.1 Japan Tangential Flow Filtration Sales and Value (2011-2016)
  6.1.1 Japan Tangential Flow Filtration Sales and Growth Rate (2011-2016)
  6.1.2 Japan Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
  6.1.3 Japan Tangential Flow Filtration Sales Price Trend (2011-2016)
6.2 Japan Tangential Flow Filtration Sales and Market Share by Manufacturers
6.3 Japan Tangential Flow Filtration Sales and Market Share by Type
6.4 Japan Tangential Flow Filtration Sales and Market Share by Application

7 INDIA TANGENTIAL FLOW FILTRATION (VOLUME, VALUE AND SALES PRICE)

7.1 India Tangential Flow Filtration Sales and Value (2011-2016)
  7.1.1 India Tangential Flow Filtration Sales and Growth Rate (2011-2016)
  7.1.2 India Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
  7.1.3 India Tangential Flow Filtration Sales Price Trend (2011-2016)
7.2 India Tangential Flow Filtration Sales and Market Share by Manufacturers
7.3 India Tangential Flow Filtration Sales and Market Share by Type
7.4 India Tangential Flow Filtration Sales and Market Share by Application

8 SOUTHEAST ASIA TANGENTIAL FLOW FILTRATION (VOLUME, VALUE AND SALES PRICE)

8.1 Southeast Asia Tangential Flow Filtration Sales and Value (2011-2016)
  8.1.1 Southeast Asia Tangential Flow Filtration Sales and Growth Rate (2011-2016)
  8.1.2 Southeast Asia Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
  8.1.3 Southeast Asia Tangential Flow Filtration Sales Price Trend (2011-2016)
8.2 Southeast Asia Tangential Flow Filtration Sales and Market Share by Manufacturers
8.3 Southeast Asia Tangential Flow Filtration Sales and Market Share by Type
8.4 Southeast Asia Tangential Flow Filtration Sales and Market Share by Application

9 GLOBAL TANGENTIAL FLOW FILTRATION MANUFACTURERS ANALYSIS

9.1 Danaher Corporation (U.S.)
  9.1.1 Company Basic Information, Manufacturing Base and Competitors
  9.1.2 Tangential Flow Filtration Product Type, Application and Specification
    9.1.2.1 Type I
    9.1.2.2 Type II
  9.1.3 Danaher Corporation (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.1.4 Main Business/Business Overview
9.2 Merck Millipore (U.S.)
  9.2.1 Company Basic Information, Manufacturing Base and Competitors
  9.2.2 129 Product Type, Application and Specification
    9.2.2.1 Type I
    9.2.2.2 Type II
  9.2.3 Merck Millipore (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.2.4 Main Business/Business Overview
9.3 Sartorius Stedim Biotech S.A. (France)
  9.3.1 Company Basic Information, Manufacturing Base and Competitors
  9.3.2 145 Product Type, Application and Specification
    9.3.2.1 Type I
    9.3.2.2 Type II
  9.3.3 Sartorius Stedim Biotech S.A. (France) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.3.4 Main Business/Business Overview
9.4 Parker Hannifin Corporation (U.S.)
  9.4.1 Company Basic Information, Manufacturing Base and Competitors
  9.4.2 Sept Product Type, Application and Specification
    9.4.2.1 Type I
    9.4.2.2 Type II
  9.4.3 Parker Hannifin Corporation (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.4.4 Main Business/Business Overview
9.5 GE Healthcare (U.S.)
  9.5.1 Company Basic Information, Manufacturing Base and Competitors
  9.5.2 Product Type, Application and Specification
    9.5.2.1 Type I
    9.5.2.2 Type II
  9.5.3 GE Healthcare (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.5.4 Main Business/Business Overview
9.6 Alfa Laval AB (Sweden)
  9.6.1 Company Basic Information, Manufacturing Base and Competitors
  9.6.2 Million USD Product Type, Application and Specification
    9.6.2.1 Type I
    9.6.2.2 Type II
  9.6.3 Alfa Laval AB (Sweden) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.6.4 Main Business/Business Overview
9.7 Spectrum Laboratories (U.S.)
  9.7.1 Company Basic Information, Manufacturing Base and Competitors
  9.7.2 Medical Devices Product Type, Application and Specification
    9.7.2.1 Type I
    9.7.2.2 Type II
  9.7.3 Spectrum Laboratories (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.7.4 Main Business/Business Overview
9.8 Novasep (U.S.)
  9.8.1 Company Basic Information, Manufacturing Base and Competitors
  9.8.2 Product Type, Application and Specification
    9.8.2.1 Type I
    9.8.2.2 Type II
  9.8.3 Novasep (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
  9.8.4 Main Business/Business Overview

10 TANGENTIAL FLOW FILTRATION MAUFACTURING COST ANALYSIS

10.1 Tangential Flow Filtration Key Raw Materials Analysis
  10.1.1 Key Raw Materials
  10.1.2 Price Trend of Key Raw Materials
  10.1.3 Key Suppliers of Raw Materials
  10.1.4 Market Concentration Rate of Raw Materials
10.2 Proportion of Manufacturing Cost Structure
  10.2.1 Raw Materials
  10.2.2 Labor Cost
  10.2.3 Manufacturing Process Analysis of Tangential Flow Filtration

11 INDUSTRIAL CHAIN, SOURCING STRATEGY AND DOWNSTREAM BUYERS

11.1 Tangential Flow Filtration Industrial Chain Analysis
11.2 Upstream Raw Materials Sourcing
11.3 Raw Materials Sources of Tangential Flow Filtration Major Manufacturers in 2015
11.4 Downstream Buyers

12 MARKETING STRATEGY ANALYSIS, DISTRIBUTORS/TRADERS

12.1 Marketing Channel
  12.1.1 Direct Marketing
  12.1.2 Indirect Marketing
  12.1.3 Marketing Channel Development Trend
12.2 Market Positioning
  12.2.1 Pricing Strategy
  12.2.2 Brand Strategy
  12.2.3 Target Client
12.3 Distributors/Traders List

13 MARKET EFFECT FACTORS ANALYSIS

13.1 Technology Progress/Risk
  13.1.1 Substitutes Threat
  13.1.2 Technology Progress in Related Industry
13.2 Consumer Needs/Customer Preference Change
13.3 Economic/Political Environmental Change

14 GLOBAL TANGENTIAL FLOW FILTRATION MARKET FORECAST (2016-2021)

14.1 Global Tangential Flow Filtration Sales, Revenue Forecast (2016-2021)
14.2 Global Tangential Flow Filtration Sales Forecast by Regions (2016-2021)
14.3 Global Tangential Flow Filtration Sales Forecast by Type (2016-2021)
14.4 Global Tangential Flow Filtration Sales Forecast by Application (2016-2021)

15 APPENDIX

Author List
Disclosure Section
Research Methodology
Data Source
China Disclaimer

List Of Tables

LIST OF TABLES AND FIGURES

Figure Picture of Tangential Flow Filtration
Table Classification of Tangential Flow Filtration
Figure Global Sales Market Share of Tangential Flow Filtration by Type in 2015
Figure Single-use Systems Picture
Figure Reusable Systems Picture
Figure Membrane Filters Picture
Figure Filtration Accessories Picture
Table Applications of Tangential Flow Filtration
Figure Global Sales Market Share of Tangential Flow Filtration by Application in 2015
Figure Bioprocessing Examples
Figure Viral Vectors and Vaccine Purification Examples
Figure Pharmaceutical Water Production Examples
Figure Other Applications? Examples
Figure USA Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Figure China Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Figure Europe Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Figure Japan Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Figure India Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Figure Southeast Asia Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Figure Global Tangential Flow Filtration Sales and Growth Rate (2011-2021)
Figure Global Tangential Flow Filtration Revenue and Growth Rate (2011-2021)
Table Global Tangential Flow Filtration Sales of Key Manufacturers (2011-2016)
Table Global Tangential Flow Filtration Sales Share by Manufacturers (2011-2016)
Figure 2015 Tangential Flow Filtration Sales Share by Manufacturers
Figure 2016 Tangential Flow Filtration Sales Share by Manufacturers
Table Global Tangential Flow Filtration Revenue by Manufacturers (2011-2016)
Table Global Tangential Flow Filtration Revenue Share by Manufacturers (2011-2016)
Table 2015 Global Tangential Flow Filtration Revenue Share by Manufacturers
Table 2016 Global Tangential Flow Filtration Revenue Share by Manufacturers
Table Global Tangential Flow Filtration Sales and Market Share by Type (2011-2016)
Table Global Tangential Flow Filtration Sales Share by Type (2011-2016)
Figure Sales Market Share of Tangential Flow Filtration by Type (2011-2016)
Figure Global Tangential Flow Filtration Sales Growth Rate by Type (2011-2016)
Table Global Tangential Flow Filtration Revenue and Market Share by Type (2011-2016)
Table Global Tangential Flow Filtration Revenue Share by Type (2011-2016)
Figure Revenue Market Share of Tangential Flow Filtration by Type (2011-2016)
Figure Global Tangential Flow Filtration Revenue Growth Rate by Type (2011-2016)
Table Global Tangential Flow Filtration Sales and Market Share by Regions (2011-2016)
Table Global Tangential Flow Filtration Sales Share by Regions (2011-2016)
Figure Sales Market Share of Tangential Flow Filtration by Regions (2011-2016)
Figure Global Tangential Flow Filtration Sales Growth Rate by Regions (2011-2016)
Table Global Tangential Flow Filtration Revenue and Market Share by Regions (2011-2016)
Table Global Tangential Flow Filtration Revenue Share by Regions (2011-2016)
Figure Revenue Market Share of Tangential Flow Filtration by Regions (2011-2016)
Figure Global Tangential Flow Filtration Revenue Growth Rate by Regions (2011-2016)
Table Global Tangential Flow Filtration Sales and Market Share by Application (2011-2016)
Table Global Tangential Flow Filtration Sales Share by Application (2011-2016)
Figure Sales Market Share of Tangential Flow Filtration by Application (2011-2016)
Figure Global Tangential Flow Filtration Sales Growth Rate by Application (2011-2016)
Figure USA Tangential Flow Filtration Sales and Growth Rate (2011-2016)
Figure USA Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
Figure USA Tangential Flow Filtration Sales Price Trend (2011-2016)
Table USA Tangential Flow Filtration Sales by Manufacturers (2011-2016)
Table USA Tangential Flow Filtration Market Share by Manufacturers (2011-2016)
Table USA Tangential Flow Filtration Sales by Type (2011-2016)
Table USA Tangential Flow Filtration Market Share by Type (2011-2016)
Table USA Tangential Flow Filtration Sales by Application (2011-2016)
Table USA Tangential Flow Filtration Market Share by Application (2011-2016)
Figure China Tangential Flow Filtration Sales and Growth Rate (2011-2016)
Figure China Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
Figure China Tangential Flow Filtration Sales Price Trend (2011-2016)
Table China Tangential Flow Filtration Sales by Manufacturers (2011-2016)
Table China Tangential Flow Filtration Market Share by Manufacturers (2011-2016)
Table China Tangential Flow Filtration Sales by Type (2011-2016)
Table China Tangential Flow Filtration Market Share by Type (2011-2016)
Table China Tangential Flow Filtration Sales by Application (2011-2016)
Table China Tangential Flow Filtration Market Share by Application (2011-2016)
Figure Europe Tangential Flow Filtration Sales and Growth Rate (2011-2016)
Figure Europe Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
Figure Europe Tangential Flow Filtration Sales Price Trend (2011-2016)
Table Europe Tangential Flow Filtration Sales by Manufacturers (2011-2016)
Table Europe Tangential Flow Filtration Market Share by Manufacturers (2011-2016)
Table Europe Tangential Flow Filtration Sales by Type (2011-2016)
Table Europe Tangential Flow Filtration Market Share by Type (2011-2016)
Table Europe Tangential Flow Filtration Sales by Application (2011-2016)
Table Europe Tangential Flow Filtration Market Share by Application (2011-2016)
Figure Japan Tangential Flow Filtration Sales and Growth Rate (2011-2016)
Figure Japan Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
Figure Japan Tangential Flow Filtration Sales Price Trend (2011-2016)
Table Japan Tangential Flow Filtration Sales by Manufacturers (2011-2016)
Table Japan Tangential Flow Filtration Market Share by Manufacturers (2011-2016)
Table Japan Tangential Flow Filtration Sales by Type (2011-2016)
Table Japan Tangential Flow Filtration Market Share by Type (2011-2016)
Table Japan Tangential Flow Filtration Sales by Application (2011-2016)
Table Japan Tangential Flow Filtration Market Share by Application (2011-2016)
Figure India Tangential Flow Filtration Sales and Growth Rate (2011-2016)
Figure India Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
Figure India Tangential Flow Filtration Sales Price Trend (2011-2016)
Table India Tangential Flow Filtration Sales by Manufacturers (2011-2016)
Table India Tangential Flow Filtration Market Share by Manufacturers (2011-2016)
Table India Tangential Flow Filtration Sales by Type (2011-2016)
Table India Tangential Flow Filtration Market Share by Type (2011-2016)
Table India Tangential Flow Filtration Sales by Application (2011-2016)
Table India Tangential Flow Filtration Market Share by Application (2011-2016)
Figure Southeast Asia Tangential Flow Filtration Sales and Growth Rate (2011-2016)
Figure Southeast Asia Tangential Flow Filtration Revenue and Growth Rate (2011-2016)
Figure Southeast Asia Tangential Flow Filtration Sales Price Trend (2011-2016)
Table Southeast Asia Tangential Flow Filtration Sales by Manufacturers (2011-2016)
Table Southeast Asia Tangential Flow Filtration Market Share by Manufacturers (2011-2016)
Table Southeast Asia Tangential Flow Filtration Sales by Type (2011-2016)
Table Southeast Asia Tangential Flow Filtration Market Share by Type (2011-2016)
Table Southeast Asia Tangential Flow Filtration Sales by Application (2011-2016)
Table Southeast Asia Tangential Flow Filtration Market Share by Application (2011-2016)
Table Danaher Corporation (U.S.) Basic Information List
Table Danaher Corporation (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Danaher Corporation (U.S.) Tangential Flow Filtration Global Market Share (2011-2016)
Table Merck Millipore (U.S.) Basic Information List
Table Merck Millipore (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Merck Millipore (U.S.) Tangential Flow Filtration Global Market Share (2011-2016)
Table Sartorius Stedim Biotech S.A. (France) Basic Information List
Table Sartorius Stedim Biotech S.A. (France) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Sartorius Stedim Biotech S.A. (France) Tangential Flow Filtration Global Market Share (2011-2016)
Table Parker Hannifin Corporation (U.S.) Basic Information List
Table Parker Hannifin Corporation (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Parker Hannifin Corporation (U.S.) Tangential Flow Filtration Global Market Share (2011-2016)
Table GE Healthcare (U.S.) Basic Information List
Table GE Healthcare (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure GE Healthcare (U.S.) Tangential Flow Filtration Global Market Share (2011-2016)
Table Alfa Laval AB (Sweden) Basic Information List
Table Alfa Laval AB (Sweden) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Alfa Laval AB (Sweden) Tangential Flow Filtration Global Market Share (2011-2016)
Table Spectrum Laboratories (U.S.) Basic Information List
Table Spectrum Laboratories (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Spectrum Laboratories (U.S.) Tangential Flow Filtration Global Market Share (2011-2016)
Table Novasep (U.S.) Basic Information List
Table Novasep (U.S.) Tangential Flow Filtration Sales, Revenue, Price and Gross Margin (2011-2016)
Figure Novasep (U.S.) Tangential Flow Filtration Global Market Share (2011-2016)
Table Production Base and Market Concentration Rate of Raw Material
Figure Price Trend of Key Raw Materials
Table Key Suppliers of Raw Materials
Figure Manufacturing Cost Structure of Tangential Flow Filtration
Figure Manufacturing Process Analysis of Tangential Flow Filtration
Figure Tangential Flow Filtration Industrial Chain Analysis
Table Raw Materials Sources of Tangential Flow Filtration Major Manufacturers in 2015
Table Major Buyers of Tangential Flow Filtration
Table Distributors/Traders List
Figure Global Tangential Flow Filtration Sales and Growth Rate Forecast (2016-2021)
Figure Global Tangential Flow Filtration Revenue and Growth Rate Forecast (2016-2021)
Table Global Tangential Flow Filtration Sales Forecast by Regions (2016-2021)
Table Global Tangential Flow Filtration Sales Forecast by Type (2016-2021)
Table Global Tangential Flow Filtration Sales Forecast by Application (2016-2021)