Global Microbots Drug Delivery Advances, Therapeutic Applications & Opportunity Insight 2025
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'Global Microbots Drug Delivery Advances, Therapeutic Applications & Opportunity Insight 2025' Report Highlights:
Medical robotics is a very promising new branch. It is a field that uses tiny robots to travel inside a patient and carry out surgery, diagnosis or drug delivery. They would have the highest scientific and societal impacts on healthcare and bioengineering applications. Milli/submilli/ micro robots are the best alternative to existing medical devices (flexible endoscopes and catheters), mobile medical milli/microrobots has the ability to access small and complex regions of the human body like blood capillaries, gastrointestinal (GI), brain, spinal cord and inside the eye while being minimally invasive. Through microrobots it is possible to access unprecedented sub millimeter size regions inside the human body which has not yet been possible by any conventional medical devices.
The most promising application of microrobots in biomedical field is for targeted drug delivery which allows doctors to inject or dispense drugs to specific or hard-to-reach areas in the body that need them. Targeted therapy boosts the concentration of therapeutics, for instance, drugs, proteins, genes, mRNA, stem cells, radioactive seeds and imaging contrast agents in a specific targeted site inside the body while keeping the side effects to a minimal level in rest of the body. Furthermore, microbots can be controlled by the clinicians which help them control the release kinetics of the drug and modulate the concentration at the therapeutic window. This adjustment would lead to prolong effect of single dose administration at the targeted region.
All the traditional methods of treatment that are presently used don’t have the potential to reach some of the inaccessible places in the human body. So whenever there is some problem in the hard-to-reach places of the body it is always a guesswork, for instance brain or neurological related concern. Even though there are advanced technologies like CT scan and MRI, these technologies provide only few images of the problematic zone in the brain but nothing concrete. There are still no technologies which can penetrate the blood brain barrier and perform a diagnosis.
Microrobots have lot of advantages in the biomedical field due to its miniature structure. It has the ability to go inside the body and reach inaccessible places and collect tissue samples to further analyze. For conducting biopsy with microrobots, especially for bone marrow biopsy or bone biopsy, there is no need for the patient to go through surgery. Also it is much less painful. In prostate biopsy with needles, multiple needle biopsies are taken at one time from the prostate gland. Sometimes to reach the prostate, a probe is inserted into the rectum. While microbots are so tiny there is no need for these painful procedures. Microbots go to the targeted site, grab onto tissue sample and taken out of the body.
In the near future microbot will definitely occupy the targeted drug delivery and minimally invasive surgery arena. As these are the most sought for and demanding line of work. Targeted drug delivery and minimally invasive surgeries will not only be less painful for the patient but will also help in cutting the healthcare expenditure. This will definitely draw the attention of the government towards the usefulness of microbots and more grants may be released for R&D on microrobotics.
Also, with growing research and development larger companies working on robotics will bend towards the medical use of the microrobots, hence providing institutes with funding to continue their research to better their product. In this fast forward and technologically driven era, microbots are meant to be the future answer to the medicinal queries and distress. With minimally to non- invasive surgeries it will be easy to treat any age of patient with complicated health conditions also. At present the microbots might be going through rough patch but it will slow transition into the best treatment method.
'Global Microbots Drug Delivery Advances, Therapeutic Applications & Opportunity Insight 2025' Report Highlights:
- Overview of Microbots
- Real Life Application of Microbots
- Microbots: Application In Medicine & Biotechnology
- Need of Microbots : Thrust To Targeted Drug Delivery Mechanism
- Technological Advancement in Medical Microrobotics
- Microbot Drug Deliver by Indication/Therapy: Cancer, Stem Cell Therapy, Blood Circulatory System, Neurological Problems & Others
Medical robotics is a very promising new branch. It is a field that uses tiny robots to travel inside a patient and carry out surgery, diagnosis or drug delivery. They would have the highest scientific and societal impacts on healthcare and bioengineering applications. Milli/submilli/ micro robots are the best alternative to existing medical devices (flexible endoscopes and catheters), mobile medical milli/microrobots has the ability to access small and complex regions of the human body like blood capillaries, gastrointestinal (GI), brain, spinal cord and inside the eye while being minimally invasive. Through microrobots it is possible to access unprecedented sub millimeter size regions inside the human body which has not yet been possible by any conventional medical devices.
The most promising application of microrobots in biomedical field is for targeted drug delivery which allows doctors to inject or dispense drugs to specific or hard-to-reach areas in the body that need them. Targeted therapy boosts the concentration of therapeutics, for instance, drugs, proteins, genes, mRNA, stem cells, radioactive seeds and imaging contrast agents in a specific targeted site inside the body while keeping the side effects to a minimal level in rest of the body. Furthermore, microbots can be controlled by the clinicians which help them control the release kinetics of the drug and modulate the concentration at the therapeutic window. This adjustment would lead to prolong effect of single dose administration at the targeted region.
All the traditional methods of treatment that are presently used don’t have the potential to reach some of the inaccessible places in the human body. So whenever there is some problem in the hard-to-reach places of the body it is always a guesswork, for instance brain or neurological related concern. Even though there are advanced technologies like CT scan and MRI, these technologies provide only few images of the problematic zone in the brain but nothing concrete. There are still no technologies which can penetrate the blood brain barrier and perform a diagnosis.
Microrobots have lot of advantages in the biomedical field due to its miniature structure. It has the ability to go inside the body and reach inaccessible places and collect tissue samples to further analyze. For conducting biopsy with microrobots, especially for bone marrow biopsy or bone biopsy, there is no need for the patient to go through surgery. Also it is much less painful. In prostate biopsy with needles, multiple needle biopsies are taken at one time from the prostate gland. Sometimes to reach the prostate, a probe is inserted into the rectum. While microbots are so tiny there is no need for these painful procedures. Microbots go to the targeted site, grab onto tissue sample and taken out of the body.
In the near future microbot will definitely occupy the targeted drug delivery and minimally invasive surgery arena. As these are the most sought for and demanding line of work. Targeted drug delivery and minimally invasive surgeries will not only be less painful for the patient but will also help in cutting the healthcare expenditure. This will definitely draw the attention of the government towards the usefulness of microbots and more grants may be released for R&D on microrobotics.
Also, with growing research and development larger companies working on robotics will bend towards the medical use of the microrobots, hence providing institutes with funding to continue their research to better their product. In this fast forward and technologically driven era, microbots are meant to be the future answer to the medicinal queries and distress. With minimally to non- invasive surgeries it will be easy to treat any age of patient with complicated health conditions also. At present the microbots might be going through rough patch but it will slow transition into the best treatment method.
1. OVERVIEW OF MICROBOTS
1.1 Introduction to Microbots
1.2 History & Evolution of Microbots
2. DESIGN OF MICROBOTS
2.1 Design
2.2 Control
3. ACTUATION OF MICROBOTS
3.1 Electromagnetic Actuators (EMA)
3.2 MEMS Based Magnetic Actuator
4. MICROBOTS WORKING MECHANISM
5. REAL LIFE APPLICATION OF MICROBOTS
5.1 Snake-Like Microbot
5.2 SWARM
5.3 Harvard’s Ambulatory Micro Robot (HAMR)
5.4 Microbees
5.5 ViRob
5.6 Micro-Scallops
6. MICROBOTS: APPLICATION IN MEDICINE & BIOTECHNOLOGY
6.1 Disease Diagnosis/Imaging
6.2 Telemetry
6.3 Targeted Therapy
6.3.1 Drug Delivery
6.3.2 Brachytherapy
6.3.3 Hyperthermia & Thermoablation
6.3.4 Stem Cell Delivery
6.4 Minimally Invasive Surgery
6.5 Tissue Engineering
6.6 Cell Manipulation
6.7 Wound Healing
6.8 Material Removal
6.8.1 Ablation
6.8.2 Biopsy
6.9 Controllable Structures
7. NEED OF MICROBOTS : THRUST TO TARGETED DRUG DELIVERY MECHANISM
8. TECHNOLOGICAL ADVANCEMENT IN MEDICAL MICROROBOTICS
8.1 Microtumblers (µTUMs)
8.2 Photolithography
8.3 3D Printing Techniques
8.4 Biocompatible & Biodegradable Materials
8.5 Wireless communication
9. MICROBOTS: CANCER TREATMENT
9.1 Drug Delivery to Tumor Cells
9.2 Minimally Invasive Surgery in Cancer Treatment
10. MICROBOTS IN OPHTHALMOLOGY
10.1 Drug Delivery Using Microbots
10.2 Microrobots For Minimally Invasive Intraocular Therapies
11. MICROBOTS IN BLOOD CIRCULATORY SYSTEM
11.1 Drug Delivery to Arteries via Microbots
11.2 Minimally Invasive Cardiovascular Surgery
12. MICROBOTS: TREATMENT & DIAGNOSIS IN GASTROINTESTINAL TRACT
12.1 Drug Delivery in GI Tract through Microbots
12.2 Diagnosis of GI Tract Using Microbots
12.3 Minimally Invasive Surgery in GI Tract
13. MICROBOTS IN TREATING RENAL AILMENTS
13.1 Targeted Drug Delivery Inside Renal System
13.2 Microbots Assisting Renal System Imaging
14. MICROBOTS INSIDE THE EAR (HEARING RESTORATION)
15. MICROBOTS FIXING NEUROLOGICAL PROBLEMS
15.1 Self Cleaning Shunt: Treating Hydrocephalus
15.2 Drug-Delivering Microbots To Treat Lacunar Strokes
16. MICROBOTS: CARRIER OF STEM CELLS
17. MICROBOTS IN DRUG DELIVERY
17.1 Locomotive Drug Delivery Particle
17.2 Different Modes Of Microbot Drug Delivery
18. GLOBAL MICROBOT DRUG DELIVERY MARKET DYNAMICS
18.1 Driving Force for Microbot Research
18.2 Microbot Drug Delivery Market Challenges
19. INTELLECTUAL PROPERTY & COMMERCIALIZATION
20. FUTURE OF MICROBOTS IN MEDICINE
1.1 Introduction to Microbots
1.2 History & Evolution of Microbots
2. DESIGN OF MICROBOTS
2.1 Design
2.2 Control
3. ACTUATION OF MICROBOTS
3.1 Electromagnetic Actuators (EMA)
3.2 MEMS Based Magnetic Actuator
4. MICROBOTS WORKING MECHANISM
5. REAL LIFE APPLICATION OF MICROBOTS
5.1 Snake-Like Microbot
5.2 SWARM
5.3 Harvard’s Ambulatory Micro Robot (HAMR)
5.4 Microbees
5.5 ViRob
5.6 Micro-Scallops
6. MICROBOTS: APPLICATION IN MEDICINE & BIOTECHNOLOGY
6.1 Disease Diagnosis/Imaging
6.2 Telemetry
6.3 Targeted Therapy
6.3.1 Drug Delivery
6.3.2 Brachytherapy
6.3.3 Hyperthermia & Thermoablation
6.3.4 Stem Cell Delivery
6.4 Minimally Invasive Surgery
6.5 Tissue Engineering
6.6 Cell Manipulation
6.7 Wound Healing
6.8 Material Removal
6.8.1 Ablation
6.8.2 Biopsy
6.9 Controllable Structures
7. NEED OF MICROBOTS : THRUST TO TARGETED DRUG DELIVERY MECHANISM
8. TECHNOLOGICAL ADVANCEMENT IN MEDICAL MICROROBOTICS
8.1 Microtumblers (µTUMs)
8.2 Photolithography
8.3 3D Printing Techniques
8.4 Biocompatible & Biodegradable Materials
8.5 Wireless communication
9. MICROBOTS: CANCER TREATMENT
9.1 Drug Delivery to Tumor Cells
9.2 Minimally Invasive Surgery in Cancer Treatment
10. MICROBOTS IN OPHTHALMOLOGY
10.1 Drug Delivery Using Microbots
10.2 Microrobots For Minimally Invasive Intraocular Therapies
11. MICROBOTS IN BLOOD CIRCULATORY SYSTEM
11.1 Drug Delivery to Arteries via Microbots
11.2 Minimally Invasive Cardiovascular Surgery
12. MICROBOTS: TREATMENT & DIAGNOSIS IN GASTROINTESTINAL TRACT
12.1 Drug Delivery in GI Tract through Microbots
12.2 Diagnosis of GI Tract Using Microbots
12.3 Minimally Invasive Surgery in GI Tract
13. MICROBOTS IN TREATING RENAL AILMENTS
13.1 Targeted Drug Delivery Inside Renal System
13.2 Microbots Assisting Renal System Imaging
14. MICROBOTS INSIDE THE EAR (HEARING RESTORATION)
15. MICROBOTS FIXING NEUROLOGICAL PROBLEMS
15.1 Self Cleaning Shunt: Treating Hydrocephalus
15.2 Drug-Delivering Microbots To Treat Lacunar Strokes
16. MICROBOTS: CARRIER OF STEM CELLS
17. MICROBOTS IN DRUG DELIVERY
17.1 Locomotive Drug Delivery Particle
17.2 Different Modes Of Microbot Drug Delivery
18. GLOBAL MICROBOT DRUG DELIVERY MARKET DYNAMICS
18.1 Driving Force for Microbot Research
18.2 Microbot Drug Delivery Market Challenges
19. INTELLECTUAL PROPERTY & COMMERCIALIZATION
20. FUTURE OF MICROBOTS IN MEDICINE
LIST OF FIGURES
Figure 1- 1: Evolution of Microbots
Figure 2-1: Major Functions of Microrobots
Figure 2-2: Main Approaches Of Designing, Building & Controlling Microrobots
Figure 2-3: Examples of On-Board & Off-Board Approaches to Mobile Microrobot Actuation & Control in 3-D
Figure 2-4: Microbots Classification On The Basis Of Material
Figure 3-1: Actuators Used In Microbots
Figure 3-2: Different Types of Actuation Approaches
Figure 4-1: Locomotion of Microbots Inspired By Microganisms
Figure 4-2: Approaches to Mimic Bacterial & Eukaryotic Flagella In Microbots
Figure 5-1: Timeline Showing the Microrobot Systems, 1996-2014
Figure 6-1: Applications of Microbots in Biomedical & Bioengineering
Figure 6-2: Microbot Used As Telemetry
Figure 6-3: Potential Application of Targeted Therapy by Microbots
Figure 6-4: Targeted Drug Delivery by Microrobotics Swarm
Figure 6-5: Applications of Microrobotics Cell Application
Figure 6-6: Material Removal by Microbots
Figure 6-7: Microbots: Possible Uses as Controllable Structures
Figure 8-1: Types of 3-D Bioprinting Technologies Based On Working Principle
Figure 8-2: Steps of 3-D Bioprinting Process
Figure 8-3: Concept of Magnetic Actuated Drug Delivery
Figure 9-1: Process of Microbot Drug Delivery for Cancer Treatment
Figure 9-2: Making Of Magnetized Spirulina for Treating Cancer
Figure 10-1: Ocular Disposition of Topically Applied Formulation to the Eye
Figure 11-1: Cage Shaped Microbot in the Utilization of Drug Delivery System
Figure 11-2: Difference between angioplasty & microbot assisted surgery
Figure 12-1: Challenges in Delivering Drug to GI Tract
Figure 15-1: SCS Ability to Prevent Blockage on a Shunt Opening (%)
Figure 15-2: Advantages of SCS
Figure 15-3: Advantages of Drug-Delivering Microbots to Treat Lacunar Strokes
Figure 16-1: Use of Microbot in Stem Cell Delivery
Figure 17-1: Objectives for Drug Delivery Particles
Figure 18-1: Drivers of Microbot Research
Figure 18-2: Unique Multivalent Functionalities of Microbots
Figure 1- 1: Evolution of Microbots
Figure 2-1: Major Functions of Microrobots
Figure 2-2: Main Approaches Of Designing, Building & Controlling Microrobots
Figure 2-3: Examples of On-Board & Off-Board Approaches to Mobile Microrobot Actuation & Control in 3-D
Figure 2-4: Microbots Classification On The Basis Of Material
Figure 3-1: Actuators Used In Microbots
Figure 3-2: Different Types of Actuation Approaches
Figure 4-1: Locomotion of Microbots Inspired By Microganisms
Figure 4-2: Approaches to Mimic Bacterial & Eukaryotic Flagella In Microbots
Figure 5-1: Timeline Showing the Microrobot Systems, 1996-2014
Figure 6-1: Applications of Microbots in Biomedical & Bioengineering
Figure 6-2: Microbot Used As Telemetry
Figure 6-3: Potential Application of Targeted Therapy by Microbots
Figure 6-4: Targeted Drug Delivery by Microrobotics Swarm
Figure 6-5: Applications of Microrobotics Cell Application
Figure 6-6: Material Removal by Microbots
Figure 6-7: Microbots: Possible Uses as Controllable Structures
Figure 8-1: Types of 3-D Bioprinting Technologies Based On Working Principle
Figure 8-2: Steps of 3-D Bioprinting Process
Figure 8-3: Concept of Magnetic Actuated Drug Delivery
Figure 9-1: Process of Microbot Drug Delivery for Cancer Treatment
Figure 9-2: Making Of Magnetized Spirulina for Treating Cancer
Figure 10-1: Ocular Disposition of Topically Applied Formulation to the Eye
Figure 11-1: Cage Shaped Microbot in the Utilization of Drug Delivery System
Figure 11-2: Difference between angioplasty & microbot assisted surgery
Figure 12-1: Challenges in Delivering Drug to GI Tract
Figure 15-1: SCS Ability to Prevent Blockage on a Shunt Opening (%)
Figure 15-2: Advantages of SCS
Figure 15-3: Advantages of Drug-Delivering Microbots to Treat Lacunar Strokes
Figure 16-1: Use of Microbot in Stem Cell Delivery
Figure 17-1: Objectives for Drug Delivery Particles
Figure 18-1: Drivers of Microbot Research
Figure 18-2: Unique Multivalent Functionalities of Microbots
