Scleroderma - Pipeline Insight, 2021
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DelveInsight’s, “Scleroderma - Pipeline Insight, 2021,” report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Scleroderma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Scleroderma: Overview
Scleroderma, also known as Systemic Sclerosis, progressive systemic sclerosis or the CREST syndrome, is a chronic skin disorder that affects the skin, connective tissues and other internal organs. The disorder takes place sin humans, when the immune system causes the body to make the protein collagen, an important component of the skin, in huge amounts. The most recognizable feature that is observed in Scleroderma patients, is the process of progressive fibrosis that is a resultant of excessive deposition of the extracellular matrix components in several tissues and organs. Other characteristics of scleroderma comprise of vascular damage, inflammation and the presence of specific autoantibodies. Systemic sclerosis has been found to cause damage to the skin, including the internal organs of the body as lungs, heart, kidneys, musculoskeletal system and the gastrointestinal tract. Amongst all these, skin sclerosis has been observed to be the major symptom of systemic sclerosis. It can also be calculated using the Rodnan skin score (mRss) and using a detectable marker of the disease activity.
'Scleroderma - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Scleroderma pipeline landscape is provided which includes the disease overview and Scleroderma treatment guidelines. The assessment part of the report embraces, in depth Scleroderma commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Scleroderma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
This segment of the Scleroderma report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Scleroderma Emerging Drugs
Further product details are provided in the repor
Scleroderma: Therapeutic Assessment
This segment of the report provides insights about the different Scleroderma drugs segregated based on following parameters that define the scope of the report, such as:
Scleroderma: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Scleroderma therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Scleroderma drugs.
Scleroderma Report Insights
Current Treatment Scenario and Emerging Therapies:
DelveInsight’s, “Scleroderma - Pipeline Insight, 2021,” report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Scleroderma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Scleroderma: Overview
Scleroderma, also known as Systemic Sclerosis, progressive systemic sclerosis or the CREST syndrome, is a chronic skin disorder that affects the skin, connective tissues and other internal organs. The disorder takes place sin humans, when the immune system causes the body to make the protein collagen, an important component of the skin, in huge amounts. The most recognizable feature that is observed in Scleroderma patients, is the process of progressive fibrosis that is a resultant of excessive deposition of the extracellular matrix components in several tissues and organs. Other characteristics of scleroderma comprise of vascular damage, inflammation and the presence of specific autoantibodies. Systemic sclerosis has been found to cause damage to the skin, including the internal organs of the body as lungs, heart, kidneys, musculoskeletal system and the gastrointestinal tract. Amongst all these, skin sclerosis has been observed to be the major symptom of systemic sclerosis. It can also be calculated using the Rodnan skin score (mRss) and using a detectable marker of the disease activity.
'Scleroderma - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Scleroderma pipeline landscape is provided which includes the disease overview and Scleroderma treatment guidelines. The assessment part of the report embraces, in depth Scleroderma commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Scleroderma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Scleroderma R&D. The therapies under development are focused on novel approaches to treat/improve Scleroderma.
This segment of the Scleroderma report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Scleroderma Emerging Drugs
- Iloprost: Eicos Sciences
- EHP-101: Emerald Health Pharmaceuticals
- HZN-825: Horizon Pharmaceuticals
- Guselkumab: Janssen Biotech
Further product details are provided in the repor
Scleroderma: Therapeutic Assessment
This segment of the report provides insights about the different Scleroderma drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Scleroderma
- Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Interdermal
- Intramuscular
- Intravenous
- Subcutaneous
- Topical.
- Molecule Type
- Monoclonal Antibody
- Recombinant Proteins
- Skin disorder therapy
- Small molecule
- Gene therapy
- Stem cell therapy
- Product Type
Scleroderma: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Scleroderma therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Scleroderma drugs.
Scleroderma Report Insights
- Scleroderma Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Scleroderma drugs?
- How many Scleroderma drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Scleroderma?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Scleroderma therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Scleroderma and their status?
- What are the key designations that have been granted to the emerging drugs?
- Eicos Sciences
- Emerald Health Pharmaceuticals
- Horizon Pharmaceuticals
- Janssen Biotech
- Beijing Continent Pharmaceutical
- Kyowa Kirin
- Cytori therapeutics
- Corbus Pharmaceuticals
- Zenyaku Kogyo
- Sanofi
- Bayer
- ASKA Pharmaceutical
- United Therapeutics
- Cumberland Pharmaceuticals
- Gesynta Pharma
- Certa Therapeutics
- Vicore Pharma
- Seagen
- CSL Behring
- arGentis Pharmaceuticals
- Mitsubishi Tanabe Pharma
- Kadmon Pharmaceuticals
- GlaxoSmithKline
- Bristol-Myers Squibb
- Camurus
- Regeneron Pharmaceuticals
- Castle Creek Biosciences
- Talaris Therapeutics
- Viela Bio
- Formation Biologics
- Chemomab therapeutics
- AnaMar
- Atlantic Healthcare
- Iloprost
- EHP-101
- HZN-825
- Guselkumab
- Pirfenidone
- KHK4827
- ECCS 50
- Lenabasum (JBT-101)
- Rituximab
- SAR156597
- Riociguat
- Rifaximin
- Treprostinil
- Ifetroban
- GS-248
- FT011
- Crisaborole
- C21
- Brentuximab Vedotin
- IgPro20
- ARG201
- Dersimelagon (MT-7117)
- Belumosudil
- Belimumab
- Abatacept
- CAM2043
- Tofacitinib
- Sarilumab
- Rilonacept
- FCX 013
- FCR001
- VIB7734
- AVID200
- CM-101
- AM 1476
- Renzapride
Introduction
Executive Summary
Scleroderma: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Scleroderma – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Scleroderma companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Scleroderma Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
Iloprost: Eicos Sciences
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
EHP-101: Emerald Health Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
CM 101: Chemomab Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
Comparative Analysis
TMB-003: Timber Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Scleroderma Key Companies
Scleroderma Key Products
Scleroderma- Unmet Needs
Scleroderma- Market Drivers and Barriers
Scleroderma- Future Perspectives and Conclusion
Scleroderma Analyst Views
Scleroderma Key Companies
Appendix
Executive Summary
Scleroderma: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Scleroderma – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Scleroderma companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Scleroderma Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
Iloprost: Eicos Sciences
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
EHP-101: Emerald Health Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
CM 101: Chemomab Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
Comparative Analysis
TMB-003: Timber Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Scleroderma Key Companies
Scleroderma Key Products
Scleroderma- Unmet Needs
Scleroderma- Market Drivers and Barriers
Scleroderma- Future Perspectives and Conclusion
Scleroderma Analyst Views
Scleroderma Key Companies
Appendix
LIST OF TABLES
Table 1 Total Products for Scleroderma
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Table 1 Total Products for Scleroderma
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
LIST OF FIGURES
Figure 1 Total Products for Scleroderma
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Figure 1 Total Products for Scleroderma
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products