North America Active Pharmaceutical Ingredients (API) Market 2022-2032 by Molecule (Small, Large), Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Country: Trend Forecast and Growth Opportunity

April 2023 | 197 pages | ID: N0641B0829BEEN
GMD Research

Abstracts

North America active pharmaceutical ingredients (API) market is projected to grow by 4.8% annually in the forecast period and reach $120.7 billion by 2032, driven by rising adoption of biologics in disease management, increasing regulatory approvals, patent expiration of major drugs, growing trend of outsourcing and increase in geriatric population.

Highlighted with 82 tables and 75 figures, this 197-page report “North America Active Pharmaceutical Ingredients (API) Market 2022-2032 by Molecule (Small, Large), Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Country: Trend Forecast and Growth Opportunity” is based on a comprehensive research of the entire North America active pharmaceutical ingredients (API) market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2020-2022 and provides forecast from 2023 till 2032 with 2022 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)

In-depth qualitative analyses include identification and investigation of the following aspects:

• Market Structure
• Growth Drivers
• Restraints and Challenges
• Emerging Product Trends & Market Opportunities
• Porter’s Fiver Forces

The trend and outlook of North America market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19 and Russia-Ukraine conflict. The balanced (most likely) projection is used to quantify North America active pharmaceutical ingredients (API) market in every aspect of the classification from perspectives of Molecule, Synthesis, Manufacturing Process, Therapeutic Application, Drug Type, and Country.

Based on Molecule, the North America market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Small Molecule APIs
• Large Molecule APIs

Based on Synthesis, the North America market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Synthetic API
• Branded Synthetic API
• Generic Synthetic API
• Biotech API
• by type
• Monoclonal Antibodies
• Recombinant Proteins
• Vaccines
• Other Biotech APIs
• by Category
• Innovative Biologic API
• Generic Biosimilar API
• by Expression
• Mammalian Expression
• Microbial Expression
• Yeast Expression
• Insect Expression
• Other Expression Technologies
• HPAPI
• Branded HPAPI
• Generic HPAPI

Based on Manufacturing Process, the North America market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Captive Manufacturing
• Branded Captive API
• Generic Captive API
• Merchant Manufacturing
• by Drug Type
• Branded Merchant API
• Generic Merchant API
• by Drug Synthesis
• Merchant Synthetic API
• Merchant Biotech API

By Therapeutic Application, the North America market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Infectious Diseases
• Oncology
• Ophthalmology
• Cardiovascular Disorders
• Central Nervous System
• Pulmonary Disorders
• Orthopedics
• Other Applications

By Drug Type, the North America market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Branded Prescription Drugs
• Generic Prescription Drugs
• OTC Drugs

Geographically, the following national/local markets are fully investigated:

• U.S.
• Canada
• Mexico

For each key country, detailed analysis and data for annual revenue ($ mn) are available for 2022-2032. The breakdown of national markets by Synthesis, Manufacturing Process, and Therapeutic Application over the forecast years are also included.

The report also covers the current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.

Selected Key Players:

AbbVie Inc.

Astrazeneca

Aurobindo Pharma Ltd.

BASF

Bayer AG

Boehringer Ingelheim

Catalent Inc.

Dr. Reddy's Laboratories

F. Hoffmann-La Roche

GlaxoSmithKline plc

Lonza Group

Lupin Limited

Merck & Co., Inc.

Mylan NV

Novartis International AG

Pfizer Inc.

Sanofi

Sun Pharmaceutical Industries Ltd.

Teva Pharmaceutical Industries Ltd.

Thermo Fisher Scientific

(Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)

Contents

1.1 Industry Definition and Research Scope
  1.1.1 Industry Definition
  1.1.2 Research Scope
1.2 Research Methodology
  1.2.1 Overview of Market Research Methodology
  1.2.2 Market Assumption
  1.2.3 Secondary Data
  1.2.4 Primary Data
  1.2.5 Data Filtration and Model Design
  1.2.6 Market Size/Share Estimation
  1.2.7 Research Limitations
1.3 Executive Summary

2 MARKET OVERVIEW AND DYNAMICS

2.1 Market Size and Forecast
  2.1.1 Impact of COVID-19 on World Economy
  2.1.2 Impact of COVID-19 on the Market
  2.1.3 Impact of Russia-Ukraine Conflict: War Slows Economic Recovery
2.2 Major Growth Drivers
2.3 Market Restraints and Challenges
2.4 Emerging Opportunities and Market Trends
2.5 Porter’s Fiver Forces Analysis

3 SEGMENTATION OF NORTH AMERICA MARKET BY MOLECULE

3.1 Market Overview by Molecule
3.2 Small Molecule APIs
3.3 Large Molecule APIs

4 SEGMENTATION OF NORTH AMERICA MARKET BY SYNTHESIS

4.1 Market Overview by Synthesis
4.2 Synthetic API
  4.2.1 Branded Synthetic API
  4.2.2 Generic Synthetic API
4.3 Biotech API
  4.3.1 Biotech API by Drug Type
    4.3.1.1 Monoclonal Antibodies
    4.3.1.2 Recombinant Proteins
    4.3.1.3 Vaccines
    4.3.1.4 Other Biotech APIs
  4.3.2 Biotech API by Category
    4.3.2.1 Innovative Biologic API
    4.3.2.2 Generic Biosimilar API
  4.3.3 Biotech API by Expression Technology
    4.3.3.1 Mammalian Expression
    4.3.3.2 Microbial Expression
    4.3.3.3 Yeast Expression
    4.3.3.4 Insect Expression
    4.3.3.5 Other Expression Technologies
4.4 HPAPI
  4.4.1 Branded HPAPI
  4.4.2 Generic HPAPI

5 SEGMENTATION OF NORTH AMERICA MARKET BY MANUFACTURING PROCESS

5.1 Market Overview by Manufacturing Process
5.2 Captive Manufacturing
  5.2.1 Branded Captive API
  5.2.2 Generic Captive API
5.3 Merchant Manufacturing
  5.3.1 Merchant Manufacturing by Drug Type
    5.3.1.1 Branded Merchant API
    5.3.1.2 Generic Merchant API
  5.3.2 Merchant Manufacturing by Drug Synthesis
    5.3.2.1 Merchant Synthetic API
    5.3.2.2 Merchant Biotech API

6 SEGMENTATION OF NORTH AMERICA MARKET BY THERAPEUTIC APPLICATION

6.1 Market Overview by Therapeutic Application
6.2 Infectious Diseases
6.3 Oncology
6.4 Ophthalmology
6.5 Cardiovascular Disorders
6.6 Central Nervous System
6.7 Pulmonary Disorders
6.8 Orthopedics
6.9 Other Applications

7 SEGMENTATION OF NORTH AMERICA MARKET BY DRUG TYPE

7.1 Market Overview by Drug Type
7.2 Branded Prescription Drugs
7.3 Generic Prescription Drugs
7.4 OTC Drugs

8 NORTH AMERICA MARKET 2022-2032 BY COUNTRY

8.1 Overview of North America Market
8.2 U.S.
8.3 Canada
8.4 Mexico

9 COMPETITIVE LANDSCAPE

9.1 Overview of Key Vendors
9.2 New Product Launch, Partnership, Investment, and M&A
9.3 Company Profiles
AbbVie Inc.
Astrazeneca
Aurobindo Pharma Ltd.
BASF
Bayer AG
Boehringer Ingelheim
Catalent Inc.
Dr. Reddy's Laboratories
F. Hoffmann-La Roche
GlaxoSmithKline plc
Lonza Group
Lupin Limited
Merck & Co., Inc.
Mylan NV
Novartis International AG
Pfizer Inc.
Sanofi
Sun Pharmaceutical Industries Ltd.
Teva Pharmaceutical Industries Ltd.
Thermo Fisher Scientific
Related Reports and Products

List Of Tables

LIST OF TABLES:

Table 1. Snapshot of North America Active Pharmaceutical Ingredients (API) Market in Balanced Perspective, 2022-2032
Table 2. World Economic Outlook, 2021-2031
Table 3. World Economic Outlook, 2021-2023
Table 4. Scenarios for Economic Impact of Ukraine Crisis
Table 5. World Health Spending by Region, $ bn, 2013-2020
Table 6. World Top 10 Pharmaceutical Companies Based on Projected R&D Spending in 2026, $ bn
Table 7. Main Product Trends and Market Opportunities in North America Active Pharmaceutical Ingredients (API) Market
Table 8. North America Active Pharmaceutical Ingredients (API) Market by Molecule, 2022-2032, $ bn
Table 9. North America Active Pharmaceutical Ingredients (API) Market by Synthesis, 2022-2032, $ bn
Table 10. North America Active Pharmaceutical Ingredients (API) Market: Synthetic API by Drug Type, 2022-2032, $ bn
Table 11. North America Active Pharmaceutical Ingredients (API) Market: Biotech API by Drug Type, 2022-2032, $ bn
Table 12. North America Active Pharmaceutical Ingredients (API) Market: Biotech API by Category, 2022-2032, $ bn
Table 13. North America Active Pharmaceutical Ingredients (API) Market: Biotech API by Expression Technology, 2022-2032, $ bn
Table 14. North America Active Pharmaceutical Ingredients (API) Market: HPAPI by Drug Type, 2022-2032, $ bn
Table 15. North America Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2022-2032, $ bn
Table 16. North America Active Pharmaceutical Ingredients (API) Market: Captive Manufacturing by Drug Type, 2022-2032, $ bn
Table 17. North America Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Type, 2022-2032, $ bn
Table 18. North America Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Synthesis, 2022-2032, $ bn
Table 19. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2022-2032, $ bn
Table 20. North America Active Pharmaceutical Ingredients (API) Market by Drug Type, 2022-2032, $ bn
Table 21. North America Active Pharmaceutical Ingredients (API) Market by Country, 2022-2032, $ bn
Table 22. U.S. Active Pharmaceutical Ingredients (API) Market by Synthesis, 2022-2032, $ bn
Table 23. U.S. Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2022-2032, $ bn
Table 24. U.S. Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2022-2032, $ bn
Table 25. Top 15 Countries Supplying API for Medicines Consumed in the US, 2019, % based on Dollar Value
Table 26. Canada Active Pharmaceutical Ingredients (API) Market by Synthesis, 2022-2032, $ bn
Table 27. Canada Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2022-2032, $ bn
Table 28. Canada Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2022-2032, $ bn
Table 29. Mexico Active Pharmaceutical Ingredients (API) Market by Synthesis, 2022-2032, $ bn
Table 30. Mexico Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2022-2032, $ bn
Table 31. Mexico Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2022-2032, $ bn
Table 32. AbbVie Inc.: Company Snapshot
Table 33. AbbVie Inc.: Business Segmentation
Table 34. AbbVie Inc.: Product Portfolio
Table 35. Astrazeneca: Company Snapshot
Table 36. Aurobindo Pharma Ltd.: Company Snapshot
Table 37. Aurobindo Pharma Ltd.: Product Portfolio
Table 38. BASF: Company Snapshot
Table 39. BASF: Business Segmentation
Table 40. Bayer AG: Company Snapshot
Table 41. Bayer AG: Business Segmentation
Table 42. Bayer AG: Product Portfolio
Table 43. Boehringer Ingelheim: Company Snapshot
Table 44. Boehringer Ingelheim: Product Portfolio
Table 45. Catalent Inc.: Company Snapshot
Table 46. Catalent Inc.: Business Segmentation
Table 47. Catalent Inc.: Product Portfolio
Table 48. Dr. Reddy's Laboratories: Company Snapshot
Table 49. Dr. Reddy's Laboratories: Business Segmentation
Table 50. F. Hoffmann-La Roche: Company Snapshot
Table 51. F. Hoffmann-La Roche: Clinical Trial Service
Table 52. F. Hoffmann-La Roche: Business Segmentation
Table 53. F. Hoffmann-La Roche: Revenue by Region
Table 54. GlaxoSmithKline: Company Snapshot
Table 55. GlaxoSmithKline: Business Segmentation
Table 56. GlaxoSmithKline: Product Portfolio
Table 57. Lonza Group: Company Snapshot
Table 58. Lonza Group: Business Segmentation
Table 59. Lonza Group: Product Portfolio
Table 60. Lupin Limited: Company Snapshot
Table 61. Lupin Limited: Business Segmentation
Table 62. Merck & Co., Inc.: Company Snapshot
Table 63. Merck & Co., Inc.: Business Segmentation
Table 64. Mylan NV: Company Snapshot
Table 65. Mylan NV: Breakdown of Revenue by Region, 2022
Table 66. Mylan NV: Breakdown of Revenue by Product Category, 2022
Table 67. Novartis International AG: Company Snapshot
Table 68. Novartis International AG: Business Segmentation
Table 69. Pfizer Inc.: Company Snapshot
Table 70. Pfizer Inc.: Business Segmentation
Table 71. Pfizer Inc.: Breakdown of Revenue by Product Category
Table 72. Pfizer Inc.: Breakdown of Revenue by Region
Table 73. Pfizer Inc.: Product Portfolio
Table 74. Sanofi: Company Snapshot
Table 75. Sanofi: Business Segmentation
Table 76. Sanofi: Breakdown of Revenue by Region
Table 77. Sun Pharmaceutical Industries Limited: Company Snapshot
Table 78. Teva Pharmaceutical Industries Ltd.: Company Snapshot
Table 79. Teva Pharmaceutical Industries Ltd.: Business Segmentation
Table 80. Thermo Fisher Scientific: Company Snapshot
Table 81. Thermo Fisher Scientific: Breakdown of Revenue by Business Segment, 2020, %
Table 82. Thermo Fisher Scientific: Breakdown of Revenue by Region, 2020, %

List Of Figures

LIST OF FIGURES:

Figure 1. Research Method Flow Chart
Figure 2. Bottom-up Approach and Top-down Approach for Market Estimation
Figure 3. North America Market Forecast in Optimistic, Conservative and Balanced Perspectives, 2022-2032
Figure 4. North America Active Pharmaceutical Ingredients (API) Market, 2022-2032, $ bn
Figure 5. Impact of COVID-19 on Business
Figure 6. Primary Drivers and Impact Factors of North America Active Pharmaceutical Ingredients (API) Market
Figure 7. GDP per capita in the World, 1960-2022, $ thousand
Figure 8. Leading Causes of Death in the World, 2000 and 2019, million
Figure 9. Worldwide Geriatric Population (60 years and above) by Regions, 2015 & 2030, million
Figure 10. World Population 65 and Over, % of Total Population, 1950-2060
Figure 11. Primary Restraints and Impact Factors of North America Active Pharmaceutical Ingredients (API) Market
Figure 12. Investment Opportunity Analysis
Figure 13. Porter’s Fiver Forces Analysis of North America Active Pharmaceutical Ingredients (API) Market
Figure 14. Breakdown of North America Active Pharmaceutical Ingredients (API) Market by Molecule, 2022-2032, % of Revenue
Figure 15. North America Addressable Market Cap in 2023-2032 by Molecule, Value ($ bn) and Share (%)
Figure 16. North America Active Pharmaceutical Ingredients (API) Market by Molecule: Small Molecule APIs, 2022-2032, $ bn
Figure 17. North America Active Pharmaceutical Ingredients (API) Market by Molecule: Large Molecule APIs, 2022-2032, $ bn
Figure 18. Breakdown of North America Active Pharmaceutical Ingredients (API) Market by Synthesis, 2022-2032, % of Revenue
Figure 19. Contribution to North America 2023-2032 Cumulative Revenue by Synthesis, Value ($ bn) and Share (%)
Figure 20. North America Active Pharmaceutical Ingredients (API) Market by Synthesis: Synthetic API, 2022-2032, $ bn
Figure 21. North America Active Pharmaceutical Ingredients (API) Market by Synthetic API: Branded Synthetic API, 2022-2032, $ bn
Figure 22. North America Active Pharmaceutical Ingredients (API) Market by Synthetic API: Generic Synthetic API, 2022-2032, $ bn
Figure 23. North America Active Pharmaceutical Ingredients (API) Market by Synthesis: Biotech API, 2022-2032, $ bn
Figure 24. North America Biotech API Market by Drug Type: Monoclonal Antibodies, 2022-2032, $ bn
Figure 25. North America Biotech API Market by Drug Type: Recombinant Proteins, 2022-2032, $ bn
Figure 26. North America Biotech API Market by Drug Type: Vaccines, 2022-2032, $ bn
Figure 27. North America Biotech API Market by Drug Type: Other Biotech APIs, 2022-2032, $ bn
Figure 28. North America Biotech API Market by Category: Innovative Biologic API, 2022-2032, $ bn
Figure 29. North America Biotech API Market by Category: Generic Biosimilar API, 2022-2032, $ bn
Figure 30. North America Biotech API Market by Expression Technology: Mammalian Expression, 2022-2032, $ bn
Figure 31. North America Biotech API Market by Expression Technology: Microbial Expression, 2022-2032, $ bn
Figure 32. North America Biotech API Market by Expression Technology: Yeast Expression, 2022-2032, $ bn
Figure 33. North America Biotech API Market by Expression Technology: Insect Expression, 2022-2032, $ bn
Figure 34. North America Biotech API Market by Expression Technology: Other Expression Technologies, 2022-2032, $ bn
Figure 35. North America Active Pharmaceutical Ingredients (API) Market by Synthesis: HPAPI, 2022-2032, $ bn
Figure 36. North America Active Pharmaceutical Ingredients (API) Market by HPAPI: Branded HPAPI, 2022-2032, $ bn
Figure 37. North America Active Pharmaceutical Ingredients (API) Market by HPAPI: Generic HPAPI, 2022-2032, $ bn
Figure 38. Breakdown of North America Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2022-2032, % of Revenue
Figure 39. Contribution to North America 2023-2032 Cumulative Revenue by Manufacturing Process, Value ($ bn) and Share (%)
Figure 40. North America Active Pharmaceutical Ingredients (API) Market by Manufacturing Process: Captive Manufacturing, 2022-2032, $ bn
Figure 41. North America Active Pharmaceutical Ingredients (API) Market by Captive Manufacturing: Branded Captive API, 2022-2032, $ bn
Figure 42. North America Active Pharmaceutical Ingredients (API) Market by Captive Manufacturing: Generic Captive API, 2022-2032, $ bn
Figure 43. North America Active Pharmaceutical Ingredients (API) Market by Manufacturing Process: Merchant Manufacturing, 2022-2032, $ bn
Figure 44. North America API Merchant Manufacturing Market by Drug Type: Branded Merchant API, 2022-2032, $ bn
Figure 45. North America API Merchant Manufacturing Market by Drug Type: Generic Merchant API, 2022-2032, $ bn
Figure 46. North America API Merchant Manufacturing Market by Drug Synthesis: Merchant Synthetic API, 2022-2032, $ bn
Figure 47. North America API Merchant Manufacturing Market by Drug Synthesis: Merchant Biotech API, 2022-2032, $ bn
Figure 48. Breakdown of North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2022-2032, % of Revenue
Figure 49. Contribution to North America 2023-2032 Cumulative Revenue by Therapeutic Application, Value ($ bn) and Share (%)
Figure 50. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Infectious Diseases, 2022-2032, $ bn
Figure 51. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Oncology, 2022-2032, $ bn
Figure 52. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Ophthalmology, 2022-2032, $ bn
Figure 53. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Cardiovascular Disorders, 2022-2032, $ bn
Figure 54. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Central Nervous System, 2022-2032, $ bn
Figure 55. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Pulmonary Disorders, 2022-2032, $ bn
Figure 56. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Orthopedics, 2022-2032, $ bn
Figure 57. North America Active Pharmaceutical Ingredients (API) Market by Therapeutic Application: Other Applications, 2022-2032, $ bn
Figure 58. Breakdown of North America Active Pharmaceutical Ingredients (API) Market by Drug Type, 2022-2032, % of Revenue
Figure 59. Contribution to North America 2023-2032 Cumulative Revenue by Drug Type, Value ($ bn) and Share (%)
Figure 60. North America Active Pharmaceutical Ingredients (API) Market by Drug Type: Branded Prescription Drugs, 2022-2032, $ bn
Figure 61. North America Active Pharmaceutical Ingredients (API) Market by Drug Type: Generic Prescription Drugs, 2022-2032, $ bn
Figure 62. North America Active Pharmaceutical Ingredients (API) Market by Drug Type: OTC Drugs, 2022-2032, $ bn
Figure 63. Breakdown of North America Active Pharmaceutical Ingredients (API) Market by Country, 2022 and 2032, % of Revenue
Figure 64. Contribution to North America 2023-2032 Cumulative Revenue by Country, Value ($ bn) and Share (%)
Figure 65. U.S. Active Pharmaceutical Ingredients (API) Market, 2022-2032, $ bn
Figure 66. Manufacturing Sites of APIs for U.S. Market by Country or Region,
Figure 67. Number and Percentage of API Facilities for the 370 U.S. Marketed Drugs on the 2019 WHO Essential Medicines List
Figure 68. Number and Percentage of API Facilities for the 370 U.S. Marketed Drugs on the 2019 WHO Essential Medicines List
Figure 69. Canada Active Pharmaceutical Ingredients (API) Market, 2022-2032, $ bn
Figure 70. Active Pharmaceutical Ingredients (API) Market in Mexico, 2022-2032, $ bn
Figure 71. Growth Stage of North America Active Pharmaceutical Ingredients (API) Industry over the Forecast Period
Figure 72. AstraZeneca: Breakdown of Revenue by Therapy Area, 2022
Figure 73. AstraZeneca: Breakdown of Revenue by Region, 2022
Figure 74. Boehringer Ingelheim: Revenue by Business Segment, 2019-2022
Figure 75. Boehringer Ingelheim: R&D Investement, 2019-2022