Human Papillomavirus Protein E6 (E6) - Pipeline Review, H2 2019

December 2019 | 114 pages | ID: H752B80260DEN
Global Markets Direct

Abstracts

Human Papillomavirus Protein E6 (E6) - Pipeline Review, H2 2019

SUMMARY

Human Papillomavirus Protein E6 (E6) pipeline Target constitutes close to 34 molecules. Out of which approximately 22 molecules are developed by companies and remaining by the universities/institutes. The latest report Human Papillomavirus Protein E6 (E6) - Pipeline Review, H2 2019, outlays comprehensive information on the Human Papillomavirus Protein E6 (E6) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Human Papillomavirus Protein E6 (E6) - The Human Papillomavirus (HPV) E6 protein is one of oncoproteins encoded by the virus. It is a 151 amino-acid peptide. It plays a major role in the induction and maintenance of cellular transformation. It acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. The complex E6/E6P targets several other substrates to degradation via the proteasome including host NFX1-91. The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. The molecules developed by companies in Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical and Discovery stages are 1, 6, 3, 1, 9 and 2 respectively. Similarly, the universities portfolio in Phase II, Phase I, Preclinical and Discovery stages comprises 2, 2, 6 and 2 molecules, respectively. Report covers products from therapy areas Oncology, Women's Health, Infectious Disease and Gastrointestinal which include indications Human Papillomavirus (HPV) Associated Cancer, Cervical Cancer, Cervical Intraepithelial Neoplasia (CIN), Head And Neck Cancer Squamous Cell Carcinoma, Human Papillomavirus Infections, Penile Cancer, Anal Cancer, Head And Neck Cancer, Oropharyngeal Cancer, Vaginal Cancer, Vulvar Cancer, Anal Dysplasia, Glioblastoma Multiforme (GBM), Lung Cancer, Melanoma, Pancreatic Cancer and Triple-Negative Breast Cancer (TNBC).

Furthermore, this report also reviews key players involved in Human Papillomavirus Protein E6 (E6) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

SCOPE

• The report provides a snapshot of the global therapeutic landscape for Human Papillomavirus Protein E6 (E6)
• The report reviews Human Papillomavirus Protein E6 (E6) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
• The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
• The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
• The report reviews key players involved in Human Papillomavirus Protein E6 (E6) targeted therapeutics and enlists all their major and minor projects
• The report assesses Human Papillomavirus Protein E6 (E6) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
• The report summarizes all the dormant and discontinued pipeline projects
• The report reviews latest news and deals related to Human Papillomavirus Protein E6 (E6) targeted therapeutics

REASONS TO BUY

• Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
• Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
• Identify and understand the targeted therapy areas and indications for Human Papillomavirus Protein E6 (E6)
• Identify the use of drugs for target identification and drug repurposing
• Identify potential new clients or partners in the target demographic
• Develop strategic initiatives by understanding the focus areas of leading companies
• Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
• Devise corrective measures for pipeline projects by understanding Human Papillomavirus Protein E6 (E6) development landscape
• Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Contents

Introduction
Global Markets Direct Report Coverage
Human Papillomavirus Protein E6 (E6) - Overview
Human Papillomavirus Protein E6 (E6) - Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Products under Development by Universities/Institutes
Human Papillomavirus Protein E6 (E6) - Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Human Papillomavirus Protein E6 (E6) - Companies Involved in Therapeutics Development
Abion Inc
AstraZeneca Plc
BioNTech SE
Cellid Co Ltd
Etubics Corp
Genexine Inc
Hookipa Pharma Inc
Immunomic Therapeutics Inc
Innovene
Inovio Pharmaceuticals Inc
Ispin Inc
Papivax LLC
Rottapharm Biotech Srl
Selecta Biosciences Inc
Touchlight Genetics Ltd
Transgene SA
UbiVac LLC
ViciniVax BV
Vir Biotechnology Inc
Human Papillomavirus Protein E6 (E6) - Drug Profiles
(bizalimogene ralaplasmid + mavilimogene ralaplasmid) - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Featured News & Press Releases
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List Of Tables

LIST OF TABLES

Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Indication, H2 2019
Number of Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019 (Contd..1), H2 2019
Products under Development by Companies, H2 2019 (Contd..2), H2 2019
Products under Development by Companies, H2 2019 (Contd..3), H2 2019
Number of Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019 (Contd..1), H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Stage and Route of Administration, H2 2019
Number of Products by Stage and Molecule Type, H2 2019
Pipeline by Abion Inc, H2 2019
Pipeline by AstraZeneca Plc, H2 2019
Pipeline by BioNTech SE, H2 2019
Pipeline by Cellid Co Ltd, H2 2019
Pipeline by Etubics Corp, H2 2019
Pipeline by Genexine Inc, H2 2019
Pipeline by Hookipa Pharma Inc, H2 2019
Pipeline by Immunomic Therapeutics Inc, H2 2019
Pipeline by Innovene, H2 2019
Pipeline by Inovio Pharmaceuticals Inc, H2 2019
Pipeline by Ispin Inc, H2 2019
Pipeline by Papivax LLC, H2 2019
Pipeline by Rottapharm Biotech Srl, H2 2019
Pipeline by Selecta Biosciences Inc, H2 2019
Pipeline by Touchlight Genetics Ltd, H2 2019
Pipeline by Transgene SA, H2 2019
Pipeline by UbiVac LLC, H2 2019
Pipeline by ViciniVax BV, H2 2019
Pipeline by Vir Biotechnology Inc, H2 2019
Dormant Projects, H2 2019
Discontinued Products, H2 2019

List Of Figures

LIST OF FIGURES

Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Top 10 Indications, H2 2019
Number of Products by Mechanism of Actions, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Routes of Administration, H2 2019
Number of Products by Stage and Routes of Administration, H2 2019
Number of Products by Molecule Types, H2 2019
Number of Products by Stage and Top 10 Molecule Types, H2 2019

COMPANIES MENTIONED

Abion Inc
AstraZeneca Plc
BioNTech SE
Cellid Co Ltd
Etubics Corp
Genexine Inc
Hookipa Pharma Inc
Immunomic Therapeutics Inc
Innovene
Inovio Pharmaceuticals Inc
Ispin Inc
Papivax LLC
Rottapharm Biotech Srl
Selecta Biosciences Inc
Touchlight Genetics Ltd
Transgene SA
UbiVac LLC
ViciniVax BV
Vir Biotechnology Inc