Global Anti-inflammatory Peptides Market Size study, by Mechanism of Action (NF-?B Inhibition, JAK/STAT Inhibition, Interleukin Inhibition, TNF-? Inhibition), by Indication (Rheumatoid Arthritis, Osteoarthritis, Gout, Multiple Sclerosis), by Source, by Route of Administration, and Regional Forecasts 2022-2032

May 2025 | 285 pages | ID: G8B58ECA7DACEN
Bizwit Research & Consulting LLP

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Global Anti-inflammatory Peptides Market is valued approximately at USD 4.39 billion in 2023 and is anticipated to grow with a phenomenal CAGR of more than 11.96% over the forecast period 2024–2032. Amid the escalating global prevalence of inflammatory diseases and autoimmune disorders, anti-inflammatory peptides have emerged as a transformative class of biomolecules, forging a new frontier in immunomodulatory therapies. Unlike traditional broad-spectrum drugs that often invite undesirable systemic side effects, these peptides offer targeted intervention at the molecular level—modulating specific signaling pathways such as NF-?B, JAK/STAT, and TNF-?. With a natural origin and high biocompatibility, they hold compelling therapeutic promise for conditions ranging from rheumatoid arthritis and osteoarthritis to multiple sclerosis and inflammatory bowel disease.

This market's ascent is being shaped by relentless innovation in peptide engineering, where breakthroughs in synthetic biology and molecular docking have drastically improved peptide stability, specificity, and delivery. Pharmaceutical companies are racing to harness the advantages of peptides—such as lower immunogenicity and enhanced bioactivity—to develop novel anti-inflammatory formulations that align with precision medicine paradigms. Additionally, the rise of biologics and biosimilars in chronic disease therapy is paving the way for anti-inflammatory peptides to be explored not just as standalone treatments, but as combination partners with conventional drugs and biologics. However, despite their therapeutic appeal, challenges surrounding peptide degradation, manufacturing scalability, and regulatory clarity pose hurdles to full-scale commercial adoption.

In response, a number of biotech and pharma players are collaborating with academic institutions to innovate novel delivery systems—ranging from oral formulations resistant to enzymatic breakdown to injectable microsphere-based sustained release platforms. Meanwhile, plant and microbial-derived peptides are gaining attention due to their renewable sourcing and relatively lower production costs, especially critical in expanding access across lower-income regions. As R&D activity intensifies, especially in the domains of interleukin inhibition and JAK/STAT modulation, multiple candidates are currently progressing through clinical trials, targeting diseases with previously unmet therapeutic needs.

Market dynamics are also being reshaped by the growing trend of decentralized clinical trials and patient-centric drug designs. Enhanced focus on outpatient and self-administered therapies is pushing the development of topical and oral peptide-based anti-inflammatories. Moreover, AI-driven peptide screening platforms are being increasingly utilized to accelerate discovery cycles and minimize attrition rates in early-phase development. Industry stakeholders are also engaging in strategic licensing deals and regional expansion tactics to penetrate high-burden markets and navigate patent cliffs with differentiated product pipelines.

Geographically, North America commands the largest share of the global anti-inflammatory peptides market, buoyed by robust funding for immunological research, advanced healthcare systems, and strong IP protection frameworks. Europe follows closely, particularly in nations like Germany and the UK, where government-backed initiatives are promoting peptide therapeutics. Meanwhile, Asia Pacific is expected to witness the most accelerated growth, underpinned by a rapidly aging population, rising healthcare expenditures, and the increasing domestic production of therapeutic peptides in countries such as China, India, and South Korea. Latin America and the Middle East & Africa are also showing encouraging momentum, supported by multinational clinical trials and growing public awareness of inflammatory disease management.

Major market player included in this report are:
  • Amgen Inc.
  • Novartis AG
  • Pfizer Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Eli Lilly and Company
  • AbbVie Inc.
  • Bristol-Myers Squibb Company
  • AstraZeneca PLC
  • GlaxoSmithKline PLC
  • Merck & Co., Inc.
  • Sanofi S.A.
  • F. Hoffmann-La Roche Ltd
  • Takeda Pharmaceutical Company Limited
  • BioCryst Pharmaceuticals, Inc.
  • Regeneron Pharmaceuticals, Inc.
The detailed segments and sub-segment of the market are explained below:

By Mechanism of Action
  • NF-?B Inhibition
  • JAK/STAT Inhibition
  • Interleukin Inhibition
  • TNF-? Inhibition
By Indication
  • Rheumatoid Arthritis
  • Osteoarthritis
  • Gout
  • Multiple Sclerosis
By Source
  • Animal Origin
  • Plant Origin
  • Microbial Origin
By Route of Administration
  • Injections
  • Oral
  • Topical
By Region:

North America
  • U.S.
  • Canada
Europe
  • UK
  • Germany
  • France
  • Spain
  • Italy
  • Rest of Europe
Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • Rest of Asia Pacific
Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
Middle East & Africa
  • Saudi Arabia
  • South Africa
  • Rest of Middle East & Africa
Years considered for the study are as follows:
  • Historical year – 2022
  • Base year – 2023
  • Forecast period – 2024 to 2032
Key Takeaways:
  • Market Estimates & Forecast for 10 years from 2022 to 2032.
  • Annualized revenues and regional level analysis for each market segment.
  • Detailed analysis of geographical landscape with Country level analysis of major regions.
  • Competitive landscape with information on major players in the market.
  • Analysis of key business strategies and recommendations on future market approach.
  • Analysis of competitive structure of the market.
  • Demand side and supply side analysis of the market.
Companies Mentioned
  • Amgen Inc.
  • Novartis AG
  • Pfizer Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Eli Lilly and Company
  • AbbVie Inc.
  • Bristol-Myers Squibb Company
  • AstraZeneca PLC
  • GlaxoSmithKline PLC
  • Merck & Co., Inc.
  • Sanofi S.A.
  • F. Hoffmann-La Roche Ltd
  • Takeda Pharmaceutical Company Limited
  • BioCryst Pharmaceuticals, Inc.
  • Regeneron Pharmaceuticals, Inc.
CHAPTER 1. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET EXECUTIVE SUMMARY

1.1. Global Market Size & Forecast (2022–2032)
1.2. Regional Summary
1.3. Segmental Summary
  1.3.1. By Mechanism of Action
  1.3.2. By Indication
  1.3.3. By Source
  1.3.4. By Route of Administration
1.4. Key Trends
1.5. Recession Impact
1.6. Analyst Recommendations & Conclusion

CHAPTER 2. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET DEFINITION AND RESEARCH ASSUMPTIONS

2.1. Research Objective
2.2. Market Definition
2.3. Research Assumptions
  2.3.1. Inclusion & Exclusion
  2.3.2. Limitations
  2.3.3. Supply Side Analysis
    2.3.3.1. Infrastructure & Capacity
    2.3.3.2. Regulatory Environment
    2.3.3.3. Manufacturing Complexity
    2.3.3.4. Economic Viability (Provider’s Perspective)
  2.3.4. Demand Side Analysis
    2.3.4.1. Disease Prevalence & Unmet Needs
    2.3.4.2. Payer & Reimbursement Trends
2.4. Estimation Methodology
2.5. Years Considered for the Study
2.6. Currency Conversion Rates

CHAPTER 3. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET DYNAMICS

3.1. Market Drivers
  3.1.1. Rising Incidence of Autoimmune and Inflammatory Diseases
  3.1.2. Advances in Peptide Engineering and Delivery Technologies
  3.1.3. Shift Toward Targeted, Biocompatible Therapeutics
3.2. Market Challenges
  3.2.1. Peptide Stability and Degradation Issues
  3.2.2. High Manufacturing and Scale-Up Costs
  3.2.3. Regulatory and Clinical Trial Complexities
3.3. Market Opportunities
  3.3.1. Growth of Biosourced and Microbial Peptides
  3.3.2. AI-Driven Peptide Discovery Platforms
  3.3.3. Expansion of Oral and Topical Delivery Formats

CHAPTER 4. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET INDUSTRY ANALYSIS

4.1. Porter’s Five Forces
  4.1.1. Bargaining Power of Suppliers
  4.1.2. Bargaining Power of Buyers
  4.1.3. Threat of New Entrants
  4.1.4. Threat of Substitutes
  4.1.5. Competitive Rivalry
4.2. PESTEL Analysis
  4.2.1. Political
  4.2.2. Economic
  4.2.3. Social
  4.2.4. Technological
  4.2.5. Environmental
  4.2.6. Legal
4.3. Top Investment Opportunities
4.4. Winning Market Strategies
4.5. Disruptive Trends
4.6. Industry Expert Perspectives
4.7. Analyst Recommendations & Conclusion

CHAPTER 5. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET SIZE & FORECASTS BY MECHANISM OF ACTION (2022–2032)

5.1. Segment Dashboard
5.2. NF-?B Inhibition: Revenue Trend Analysis, 2022 & 2032
5.3. JAK/STAT Inhibition: Revenue Trend Analysis, 2022 & 2032
5.4. Interleukin Inhibition: Revenue Trend Analysis, 2022 & 2032
5.5. TNF-? Inhibition: Revenue Trend Analysis, 2022 & 2032

CHAPTER 6. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET SIZE & FORECASTS BY INDICATION (2022–2032)

6.1. Segment Dashboard
6.2. Rheumatoid Arthritis: 2022 & 2032
6.3. Osteoarthritis: 2022 & 2032
6.4. Gout: 2022 & 2032
6.5. Multiple Sclerosis: 2022 & 2032

CHAPTER 7. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET SIZE & FORECASTS BY SOURCE (2022–2032)

7.1. Segment Dashboard
7.2. Animal Origin: 2022 & 2032
7.3. Plant Origin: 2022 & 2032
7.4. Microbial Origin: 2022 & 2032

CHAPTER 8. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET SIZE & FORECASTS BY ROUTE OF ADMINISTRATION (2022–2032)

8.1. Segment Dashboard
8.2. Injections: 2022 & 2032
8.3. Oral: 2022 & 2032
8.4. Topical: 2022 & 2032

CHAPTER 9. GLOBAL ANTI-INFLAMMATORY PEPTIDES MARKET SIZE & FORECASTS BY REGION (2022–2032)

9.1. North America Market
  9.1.1. U.S. Market
  9.1.2. Canada Market
9.2. Europe Market
  9.2.1. UK Market
  9.2.2. Germany Market
  9.2.3. France Market
  9.2.4. Spain Market
  9.2.5. Italy Market
  9.2.6. Rest of Europe Market
9.3. Asia Pacific Market
  9.3.1. China Market
  9.3.2. India Market
  9.3.3. Japan Market
  9.3.4. Australia Market
  9.3.5. South Korea Market
  9.3.6. Rest of Asia Pacific Market
9.4. Latin America Market
  9.4.1. Brazil Market
  9.4.2. Mexico Market
  9.4.3. Rest of Latin America Market
9.5. Middle East & Africa Market
  9.5.1. Saudi Arabia Market
  9.5.2. South Africa Market
  9.5.3. Rest of Middle East & Africa Market

CHAPTER 10. COMPETITIVE INTELLIGENCE

10.1. Key Company SWOT Analysis
  10.1.1. Amgen Inc.
  10.1.2. Novartis AG
  10.1.3. Pfizer Inc.
10.2. Top Market Strategies
10.3. Company Profiles
  10.3.1. Amgen Inc.
    10.3.1.1. Key Information
    10.3.1.2. Overview
    10.3.1.3. Financial (Subject to Data Availability)
    10.3.1.4. Product Summary
    10.3.1.5. Market Strategies
  10.3.2. Novartis AG
  10.3.3. Pfizer Inc.
  10.3.4. Teva Pharmaceutical Industries Ltd.
  10.3.5. Eli Lilly and Company
  10.3.6. AbbVie Inc.
  10.3.7. Bristol-Myers Squibb Company
  10.3.8. AstraZeneca PLC
  10.3.9. GlaxoSmithKline PLC
  10.3.10. Merck & Co., Inc.
  10.3.11. Sanofi S.A.
  10.3.12. F. Hoffmann-La Roche Ltd
  10.3.13. Takeda Pharmaceutical Company Limited
  10.3.14. BioCryst Pharmaceuticals, Inc.
  10.3.15. Regeneron Pharmaceuticals, Inc.

CHAPTER 11. RESEARCH PROCESS

11.1. Data Mining
11.2. Analysis
11.3. Market Estimation
11.4. Validation
11.5. Publishing
11.6. Research Attributes

LIST OF TABLES

TABLE 1. Global Anti-inflammatory Peptides Market, Report Scope
TABLE 2. Global Market Estimates & Forecasts by Region (2022–2032)
TABLE 3. Global Market Estimates & Forecasts by Mechanism of Action (2022–2032)
TABLE 4. Global Market Estimates & Forecasts by Indication (2022–2032)
TABLE 5. Global Market Estimates & Forecasts by Source (2022–2032)
TABLE 6. Global Market Estimates & Forecasts by Route of Administration (2022–2032)
TABLE 7. North America Market Estimates & Forecasts, 2022–2032
TABLE 8. U.S. Market Estimates & Forecasts by Segment, 2022–2032
TABLE 9. Canada Market Estimates & Forecasts by Segment, 2022–2032
TABLE 10. Europe Market Estimates & Forecasts, 2022–2032
TABLE 11. Asia Pacific Market Estimates & Forecasts, 2022–2032
TABLE 12. Latin America Market Estimates & Forecasts, 2022–2032
TABLE 13. Middle East & Africa Market Estimates & Forecasts, 2022–2032
TABLE 14. Competitive Landscape: Market Shares of Top 10 Companies (2023)
TABLE 15. R&D Expenditure by Leading Players (2022)
TABLE 16. Peptide Pipeline by Mechanism of Action (2023)
TABLE 17. Oral vs. Injectable Route Adoption Rates (2023)
TABLE 18. Regional Pricing and Reimbursement Comparison (2023)
TABLE 19. Clinical Trial Landscape by Indication (2023)
TABLE 20. Forecasted Impact of AI on Peptide Discovery (2024–2032)

LIST OF FIGURES

FIG 1. Research Methodology Flowchart
FIG 2. Market Estimation Techniques
FIG 3. Global Market Size: Historical vs. Forecast
FIG 4. Key Trends Shaping the Market
FIG 5. CAGR Outlook by Segment (2024–2032)
FIG 6. Porter’s Five Forces Analysis
FIG 7. PESTEL Analysis Summary
FIG 8. Value Chain Analysis
FIG 9. Market Share by Mechanism of Action (2023)
FIG 10. Market Share by Indication (2023)
FIG 11. Market Share by Source (2023)
FIG 12. Market Share by Route of Administration (2023)
FIG 13. Regional Snapshot: 2022 vs. 2032
FIG 14. North America Market Trend (2022–2032)
FIG 15. Europe Market Trend (2022–2032)
FIG 16. Asia Pacific Market Trend (2022–2032)
FIG 17. Latin America Market Trend (2022–2032)
FIG 18. Middle East & Africa Market Trend (2022–2032)
FIG 19. Competitive Positioning Map
FIG 20. AI-Enabled Peptide Discovery Workflow


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