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Glabellar lines - Pipeline Insight, 2021

June 2021 | 60 pages | ID: G2B9EF2C93B8EN
DelveInsight

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DelveInsight’s, “Glabellar lines - Pipeline Insight, 2021,” report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in Glabellar lines pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Glabellar lines Understanding

Glabellar lines: Overview

Glabellar lines or glabella lines appear in the glabella, the skin over the forehead, between and above the eyebrows and right above the nose. When a person wrinkle his/her face by talking, yawning, laughing, or making expressions, the glabella is the skin most affected by the muscle activity beneath the surface. Over time, as a result of a combination of causes including genetics, skin tightness, muscle activity, face shape, and various intrinsic and extrinsic causes, the lines that appear in your glabella may remain permanently, evolving into wavy furrows in the forehead. These are known as glabellar lines and they can continuously worsen over time if not treated.

'Glabellar lines - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Glabellar lines pipeline landscape is provided which includes the disease overview and Glabellar lines treatment guidelines. The assessment part of the report embraces, in depth Glabellar lines commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Glabellar lines collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Glabellar lines R&D. The therapies under development are focused on novel approaches to treat/improve Glabellar lines.
Glabellar lines Emerging Drugs Chapters

This segment of the Glabellar lines report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Glabellar lines Emerging Drugs
  • ATGC-100: EuBiologics
ATGC-100 is botulinum toxin A just like Allergan’s Botox. Eubiologics and ATGC are jointly developing ATGC-100. Botulinum Toxin is a toxin produced only by the gram-positive anaerobic bacteria, Clostridium botulinum, inducing temporary muscle paralysis by reversibly blocking the secretion of acetylcholine at a neuromuscular junction.
  • DaxibotulinumtoxinA for Injection (DAXI): Revance Therapeutics
DaxibotulinumtoxinA for Injection is an investigational agent that has not been approved by the FDA and is currently under regulatory review. DAXI has been evaluated in three Phase 3 trials (SAKURA 1, 2, 3), the largest aesthetic neuromodulator clinical program ever conducted for the treatment of glabellar (frown) lines. In the Phase 3 pivotal program, the median time to loss of none or mild wrinkle severity was 24 weeks and the median time to return to baseline wrinkle severity was approximately 28 weeks.

Further product details are provided in the report..

Glabellar lines: Therapeutic Assessment

This segment of the report provides insights about the different Glabellar lines drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Glabellar lines
There are approx. 4+ key companies which are developing the therapies for Glabellar lines. The companies which have their Glabellar lines drug candidates in the most advanced stage, i.e. preregistration include, Revance Therapeutics.
  • Phases
DelveInsight’s report covers around 4+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Glabellar lines pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical.
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Glabellar lines: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Glabellar lines therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Glabellar lines drugs.

Glabellar lines Report Insights
  • Glabellar lines Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Glabellar lines Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Glabellar lines drugs?
  • How many Glabellar lines drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Glabellar lines?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Glabellar lines therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Glabellar lines and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • ATGC Biotech
  • EuBiologics
  • Ipsen
  • Bonti
  • Eirion Therapeutics
  • Roche
  • Galderma
Key Products
  • ATGC-100
  • Daxibotulinumtoxin A
  • IPN-10200
  • EB-001
  • AI-09
  • RelabotulinumtoxinA
Introduction
Executive Summary
Glabellar lines: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Glabellar lines – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  Glabellar lines companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Glabellar lines Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
DaxibotulinumtoxinA for Injection (DAXI): Revance Therapeutics
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Mid Stage Products (Phase II)
  Comparative Analysis
EB-001: Bonti
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Early Stage Products (Phase I/II)
  Comparative Analysis
IPN-10200: Ipsen
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Preclinical and Discovery Stage Products
  Comparative Analysis
AI-09: Eirion Therapeutics
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..


Inactive Products
  Comparative Analysis
Glabellar lines Key Companies
Glabellar lines Key Products
Glabellar lines- Unmet Needs
Glabellar lines- Market Drivers and Barriers
Glabellar lines- Future Perspectives and Conclusion
Glabellar lines Analyst Views
Glabellar lines Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for Glabellar lines
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products


LIST OF FIGURES

Figure 1 Total Products for Glabellar lines
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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