Chronic lymphocytic leukemia - Pipeline Insight, 2021
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DelveInsight’s, “Chronic lymphocytic leukemia – Pipeline Insight, 2021,” report provides comprehensive insights about 60+ companies and 60+ pipeline drugs in Chronic lymphocytic leukemia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Chronic lymphocytic leukemia: Overview
Chronic lymphocytic leukemia (also called CLL) is a cancer of the blood and bone marrow that usually gets worse slowly. CLL is one of the most common types of leukemia in adults. It often occurs during or after middle age; it rarely occurs in children. In the beginning, CLL does not cause any signs or symptoms and may be found during a routine blood test. Later, signs and symptoms may occur. Some of the major symptoms include: Painless swelling of the lymph nodes in the neck, underarm, stomach, or groin, Weakness or feeling tired, Pain or a feeling of fullness below the ribs, Fever and infection, Easy bruising or bleeding. CLL happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of these genetic changes is unknown, so it's hard to predict who might get CLL. There are a few factors that might raise the risk. CLL diagnosis is made via; Physical exam and health history, differential complete blood count, Lactate dehydrogenase testing, blood chemistry studies, Beta-2-microglobulin testing, and several others. Chemoimmunotherapy using anti-CD20 monoclonal antibodies has thus become the standard treatment for most patients with chronic lymphocytic leukaemia, irrespective of age. Idelalisib in combination with rituximab or the anti-CD20 monoclonal antibody ofatumumab is recommended for patients with TP53 aberration who are not suitable for alternative first-line treatment options.
'Chronic lymphocytic leukemia - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Chronic lymphocytic leukemia pipeline landscape is provided which includes the disease overview and Chronic lymphocytic leukemia treatment guidelines. The assessment part of the report embraces, in depth Chronic lymphocytic leukemia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Chronic lymphocytic leukemia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
This segment of the Chronic lymphocytic leukemia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Chronic lymphocytic leukemia Emerging Drugs
Further product details are provided in the report.
Chronic lymphocytic leukemia: Therapeutic Assessment
This segment of the report provides insights about the different Chronic lymphocytic leukemia drugs segregated based on following parameters that define the scope of the report, such as:
Chronic lymphocytic leukemia: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Chronic lymphocytic leukemia therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Chronic lymphocytic leukemia drugs.
Chronic lymphocytic leukemia Report Insights
Current Treatment Scenario and Emerging Therapies:
DelveInsight’s, “Chronic lymphocytic leukemia – Pipeline Insight, 2021,” report provides comprehensive insights about 60+ companies and 60+ pipeline drugs in Chronic lymphocytic leukemia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Chronic lymphocytic leukemia: Overview
Chronic lymphocytic leukemia (also called CLL) is a cancer of the blood and bone marrow that usually gets worse slowly. CLL is one of the most common types of leukemia in adults. It often occurs during or after middle age; it rarely occurs in children. In the beginning, CLL does not cause any signs or symptoms and may be found during a routine blood test. Later, signs and symptoms may occur. Some of the major symptoms include: Painless swelling of the lymph nodes in the neck, underarm, stomach, or groin, Weakness or feeling tired, Pain or a feeling of fullness below the ribs, Fever and infection, Easy bruising or bleeding. CLL happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of these genetic changes is unknown, so it's hard to predict who might get CLL. There are a few factors that might raise the risk. CLL diagnosis is made via; Physical exam and health history, differential complete blood count, Lactate dehydrogenase testing, blood chemistry studies, Beta-2-microglobulin testing, and several others. Chemoimmunotherapy using anti-CD20 monoclonal antibodies has thus become the standard treatment for most patients with chronic lymphocytic leukaemia, irrespective of age. Idelalisib in combination with rituximab or the anti-CD20 monoclonal antibody ofatumumab is recommended for patients with TP53 aberration who are not suitable for alternative first-line treatment options.
'Chronic lymphocytic leukemia - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Chronic lymphocytic leukemia pipeline landscape is provided which includes the disease overview and Chronic lymphocytic leukemia treatment guidelines. The assessment part of the report embraces, in depth Chronic lymphocytic leukemia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Chronic lymphocytic leukemia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Chronic lymphocytic leukemia R&D. The therapies under development are focused on novel approaches to treat/improve Chronic lymphocytic leukemia.
This segment of the Chronic lymphocytic leukemia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Chronic lymphocytic leukemia Emerging Drugs
- Ublituximab: TG Therapeutics
- LOXO305: Loxo Oncology
- Cirmtuzumab: Oncternal Therapeutics
- Olaptesed pegol: NOXXON Pharma
Further product details are provided in the report.
Chronic lymphocytic leukemia: Therapeutic Assessment
This segment of the report provides insights about the different Chronic lymphocytic leukemia drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Chronic lymphocytic leukemia
- Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Oral
- Parenteral
- Intravenous
- Subcutaneous
- Topical
- Molecule Type
- Monoclonal Antibody
- Peptides
- Polymer
- Small molecule
- Gene therapy
- Product Type
Chronic lymphocytic leukemia: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Chronic lymphocytic leukemia therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Chronic lymphocytic leukemia drugs.
Chronic lymphocytic leukemia Report Insights
- Chronic lymphocytic leukemia Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Chronic lymphocytic leukemia drugs?
- How many Chronic lymphocytic leukemia drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Chronic lymphocytic leukemia?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Chronic lymphocytic leukemia therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Chronic lymphocytic leukemia and their status?
- What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
Chronic lymphocytic leukemia: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
Comparative Analysis
Ublituximab: TG Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report.
Mid Stage Products (Phase II)
Comparative Analysis
Cirmtuzumab: Oncternal Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report.
Early stage products (Phase I)
Comparative Analysis
NX-2127: Nurix
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report.
Inactive Products
Comparative Analysis
Chronic lymphocytic leukemia Key Companies
Chronic lymphocytic leukemia Key Products
Chronic lymphocytic leukemia- Unmet Needs
Chronic lymphocytic leukemia- Market Drivers and Barriers
Chronic lymphocytic leukemia- Future Perspectives and Conclusion
Chronic lymphocytic leukemia Analyst Views
Chronic lymphocytic leukemia Key Companies
Appendix
Executive Summary
Chronic lymphocytic leukemia: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
Comparative Analysis
Ublituximab: TG Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report.
Mid Stage Products (Phase II)
Comparative Analysis
Cirmtuzumab: Oncternal Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report.
Early stage products (Phase I)
Comparative Analysis
NX-2127: Nurix
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report.
Inactive Products
Comparative Analysis
Chronic lymphocytic leukemia Key Companies
Chronic lymphocytic leukemia Key Products
Chronic lymphocytic leukemia- Unmet Needs
Chronic lymphocytic leukemia- Market Drivers and Barriers
Chronic lymphocytic leukemia- Future Perspectives and Conclusion
Chronic lymphocytic leukemia Analyst Views
Chronic lymphocytic leukemia Key Companies
Appendix
LIST OF TABLES
Table 1 Total Products for Chronic lymphocytic leukemia
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Table 1 Total Products for Chronic lymphocytic leukemia
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
LIST OF FIGURES
Figure 1 Total Products for Chronic lymphocytic leukemia
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Figure 1 Total Products for Chronic lymphocytic leukemia
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products