[email protected] +44 20 8123 2220 (UK) +1 732 587 5005 (US) Contact Us | FAQ |

Chronic Idiopathic Urticaria - Pipeline Insight, 2021

July 2021 | 60 pages | ID: CCE88975A75EEN
DelveInsight

US$ 2,000.00

E-mail Delivery (PDF)

Download PDF Leaflet

Accepted cards
Wire Transfer
Checkout Later
Need Help? Ask a Question
This report can be delivered to the clients within 72 Hours

DelveInsight’s, “Chronic Idiopathic Urticaria - Pipeline Insight, 2021,” report provides comprehensive insights about 20+ companies and 20+ pipeline drugs in Chronic Idiopathic Urticaria pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Chronic Idiopathic Urticaria Understanding

Chronic Idiopathic Urticaria: Overview

Chronic Urticaria (CU) conventionally refers to recurrent wheals, on most days of the week, which occur for a period of ? six weeks. CU can be further divided into two different subtypes, namely, chronic idiopathic urticaria (also called chronic spontaneous urticaria) and chronic inducible urticaria (also called physical urticaria). In most patients, CU is a sporadic and self-limited disorder. Chronic spontaneous urticaria refers to chronic urticaria that has no specific cause or trigger. Weals are present on most days of the week for 6 weeks or more. Chronic spontaneous urticaria was previously referred to as chronic idiopathic urticaria. This term is no longer used as many cases have an autoimmune basis.

'Chronic Idiopathic Urticaria - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Chronic Idiopathic Urticaria pipeline landscape is provided which includes the disease overview and Chronic Idiopathic Urticaria treatment guidelines. The assessment part of the report embraces, in depth Chronic Idiopathic Urticaria commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Chronic Idiopathic Urticaria collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Chronic Idiopathic Urticaria R&D. The therapies under development are focused on novel approaches to treat/improve Chronic Idiopathic Urticaria.
Chronic Idiopathic Urticaria Emerging Drugs Chapters

This segment of the Chronic Idiopathic Urticaria report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Chronic Idiopathic Urticaria Emerging Drugs
  • Ligelizumab: Novartis
Ligelizumab (QGE031) is a next generation monoclonal anti-immunoglobulin E (IgE) antibody. Ligelizumab is thought to work by blocking the IgE/Fc?RI pathway, a key driver of the inflammatory process in CSU. Ligelizumab (QGE031) had received FDA Breakthrough Therapy designation for patients with chronic spontaneous urticaria (CSU). Ligelizumab is the first treatment to receive FDA Breakthrough Therapy designation in chronic spontaneous urticaria (CSU) in patients with an inadequate response to H1-antihistamines
  • Dupilumab: Regeneron
It is a human monoclonal antibody of the immunoglobulin G4 subclass that inhibits IL-4 and interleukin-13 (IL-13) signaling by specifically binding to the IL-4 receptor alpha subunit, which is shared by the IL-4 and IL-13 receptor complexes. It is in phase III stage of development to treat Chronic Spontaneous Urticaria.
  • Tezepelumab: Amgen
Tezepelumab is an investigational, potential first-in-class human monoclonal antibody that works on the primary source of inflammation: the airway epithelium, which is the first point of contact for viruses, allergens, pollutants and other environmental insults. Specifically, tezepelumab targets and blocks thymic stromal lymphopoietin (TSLP), a key epithelial cytokine that sits at the top of multiple inflammatory cascades and initiates an overreactive immune response to allergic, eosinophilic and other types of airway inflammation associated with severe asthma

Further product details are provided in the report……..

Chronic Idiopathic Urticaria: Therapeutic Assessment

This segment of the report provides insights about the different Chronic Idiopathic Urticaria drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Chronic Idiopathic Urticaria
There are approx. 20+ key companies which are developing the therapies for Chronic Idiopathic Urticaria. The companies which have their Chronic Idiopathic Urticaria drug candidates in the most advanced stage, i.e. phase III include, Novartis.
  • Phases
DelveInsight’s report covers around 20+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Chronic Idiopathic Urticaria pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • intravenous
  • Subcutaneous
  • Topical.
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Chronic Idiopathic Urticaria: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Chronic Idiopathic Urticaria therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Chronic Idiopathic Urticaria drugs.

Chronic Idiopathic Urticaria Report Insights
  • Chronic Idiopathic Urticaria Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Chronic Idiopathic Urticaria Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Chronic Idiopathic Urticaria drugs?
  • How many Chronic Idiopathic Urticaria drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Chronic Idiopathic Urticaria?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Chronic Idiopathic Urticaria therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Chronic Idiopathic Urticaria and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • Novartis
  • Regeneron
  • Amgen
  • AstraZeneca
  • United BioPharma
  • Celltrion
  • Celldex Therapeutics
  • CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
  • Gilead Sciences
  • Stero Biotechs Ltd.
  • UCB Biopharma SRL
  • GlaxoSmithKline
  • UBP Greater China (Shanghai) Co., Ltd
  • Genentech
  • Kiniksa Pharmaceuticals, Ltd.
Key Products
  • Ligelizumab
  • Dupilumab
  • Tezepelumab
  • Benralizumab
  • UB-221
  • CT-P39
  • CDX-0159
  • SYN008
  • Tirabrutinib
  • UCB8600
  • Nucala
  • UB-221
  • GDC-0853
  • KPL-716
Introduction
Executive Summary
Chronic Idiopathic Urticaria: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
  Comparative Analysis
Ligelizumab: Novartis
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  Comparative Analysis
Tezepelumab: Amgen
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
  Comparative Analysis
UCB8600: UCB Pharma
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
  Comparative Analysis
Drug name: Company name
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..

Inactive Products
  Comparative Analysis
Chronic Idiopathic Urticaria Key Companies
Chronic Idiopathic Urticaria Key Products
Chronic Idiopathic Urticaria- Unmet Needs
Chronic Idiopathic Urticaria- Market Drivers and Barriers
Chronic Idiopathic Urticaria- Future Perspectives and Conclusion
Chronic Idiopathic Urticaria Analyst Views
Chronic Idiopathic Urticaria Key Companies
Appendix


LIST OF TABLES

Table 1 Total Products for Chronic Idiopathic Urticaria
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products


LIST OF FIGURES

Figure 1 Total Products for Chronic Idiopathic Urticaria
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


More Publications