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Chlamydia - Pipeline Insight, 2021

July 2021 | 60 pages | ID: C1825F7A3AF5EN
DelveInsight

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DelveInsight’s, “Chlamydia – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Chlamydia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Chlamydia Understanding

Chlamydia: Overview

Chlamydia is a sexually transmitted infection (STI) caused by a bacteria called chlamydia trachomatis. It can cause serious, permanent damage to a woman’s reproductive system. Chlamydia is usually passed on through unprotected vaginal, anal or oral sex. Chlamydia can be passed on through genital contact.

Signs of chlamydia in women include:
  • increase in vaginal discharge
  • pain or burning when urinating (peeing)
  • pain during sex and/or bleeding after sex
  • pain in the lower stomach – especially when having sex
  • bleeding between periods and/or heavier periods.
Signs of chlamydia in men include:
  • white, cloudy or watery discharge from the penis
  • pain or burning when urinating
  • pain and/or swelling in the testicles.
Getting tested for chlamydia is easy and doesn’t hurt. A healthcare professional will ask for a urine (pee) sample and/or take a swab from the area that might be infected. This is usually the lower part of the womb (cervix) or the vagina for women, and the tip of the penis (urethra) for men. Azithromycin is an antibiotic usually prescribed in a single, large dose. Doxycycline is an antibiotic that must be taken twice per day for about one week. Other antibiotics may also be given.

'Chlamydia - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Chlamydia pipeline landscape is provided which includes the disease overview and Chlamydia treatment guidelines. The assessment part of the report embraces, in depth Chlamydia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Chlamydia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Chlamydia R&D. The therapies under development are focused on novel approaches to treat/improve Chlamydia.
Chlamydia Emerging Drugs Chapters

This segment of the Chlamydia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Chlamydia Emerging Drugs
  • EVO100: Evofem
EVO100 vaginal gel is designed to reduce certain vaginal infections by: Balancing vaginal pH, thereby maintaining healthy vaginal flora and creating an environment that is detrimental to the growth and proliferation of harmful bacteria and using a different mechanism of action that may help to address drug resistance concerns. In October 2020, Evofem initiated EVOGUARD, a pivotal Phase III clinical trial to evaluate the safety and efficacy of EVO100 for the prevention of urogenital Chlamydia trachomatis and Neisseria gonorrhoeae infection in women. Top-line results are expected in 2022.
  • Chlamydia Vaccine Candidate: Eurocine Vaccines AB
Eurocine Vaccines AB is developing a Chlamydia Vaccine Candidate. They have successfully identified sections of the MOMP (Major Outer Membrane Protein) in the bacterium Chlamydia trachomatis – sequences that can be used to stimulate an immune response. The specially designed protein chains are essential for the creation of the vaccine and are patent protected. Eurocine Vaccines entered into a collaboration and license agreement with Spixia Biotechnology for the development and commercialization of Chlamydia vaccines. Under the agreement, Eurocine Vaccines receives an exclusive right to develop, manufacture and commercialize vaccine candidates against Chlamydia based on vaccine antigens that Spixia Biotechnology has developed.

Further product details are provided in the report……..

Chlamydia: Therapeutic Assessment

This segment of the report provides insights about the different Chlamydia drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Chlamydia
There are approx. 10+ key companies which are developing the therapies for Chlamydia. The companies which have their Chlamydia drug candidates in the most advanced stage, i.e. Phase III include, Evofem.
  • Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Chlamydia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Chlamydia: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Chlamydia therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Chlamydia drugs.

Chlamydia Report Insights
  • Chlamydia Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Chlamydia Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Chlamydia drugs?
  • How many Chlamydia drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Chlamydia?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Chlamydia therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Chlamydia and their status?
  • What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
Chlamydia: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
  Comparative Analysis
EVO100: Evofem
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  Comparative Analysis
Drug Name: Company Name
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Preclinical stage products (Phase I/II)
  Comparative Analysis
Chlamydia Vaccine Candidate: Eurocine Vaccines AB
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  Comparative Analysis
Chlamydia Key Companies
Chlamydia Key Products
Chlamydia- Unmet Needs
Chlamydia- Market Drivers and Barriers
Chlamydia- Future Perspectives and Conclusion
Chlamydia Analyst Views
Chlamydia Key Companies
Appendix


LIST OF TABLES

Table 1 Total Products for Chlamydia
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products


LIST OF FIGURES

Figure 1 Total Products for Chlamydia
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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