Charcot Marie Tooth (CMT) - Market Insights, Epidemiology and Market Forecast-2027
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DelveInsight’s Charcot Marie Tooth (CMT) - Market Insights, Epidemiology and Market Forecast-2027’ report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Charcot Marie Tooth (CMT) in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom) and Japan.
The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Charcot Marie Tooth (CMT) from 2016 to 2027 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.
Geography Covered
Charcot Marie Tooth - Disease Understanding and Treatment Algorithm
According to Charcot-Marie-Tooth Association (CMTA), CMT is a disease of the peripheral nerves that control muscles (unlike the muscular dystrophies, which affect the muscles themselves).It is a group of genetically heterogeneous disorders which affect the motor and/or sensory peripheral nerves, resulting in muscle weakness and atrophy in addition to sensory loss.
The many different types of Charcot Marie Tooth (CMT) are distinguished by age of onset, inheritance pattern, severity, and whether they're linked to defects in axon or myelin. Charcot Marie Tooth (CMT) can be divided into types and subtypes. The types are the clinical pictures of Charcot Marie Tooth (CMT) (CMT type 1, 2, 4, X, etc.), are usually defined by inheritance pattern and nerve conductions. Subtypes (CMT1A, 2B, 4C, X1, etc.) are given only when the genetic cause is known.
The exact symptoms of Charcot Marie Tooth (CMT) vary from person to person partly because there are different types of CMT. It may cause muscle weakness, contractures and bone deformities, sensory loss.
The DelveInsight Charcot Marie Tooth (CMT) market report gives the thorough understanding of the CMT by including details such as disease definition, symptoms, types, causes, genetics and inheritance, pathophysiology, and diagnosis. It also provides treatment algorithms and treatment guidelines for Charcot Marie Tooth (CMT) in the US, Europe, and Japan.
Charcot Marie Tooth Epidemiology
The Charcot Marie Tooth (CMT) epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology [segmented as Total Prevalent Population of Charcot Marie Tooth (CMT), Type Specific Prevalent Population of Charcot Marie Tooth (CMT) and Diagnosed Cases of Charcot Marie Tooth (CMT)] scenario of CMT in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom), and Japan from 2016-2027.
Charcot Marie Tooth (CMT) is one of the most commonly inherited neuropathy in the United States with an estimated prevalence of one in 2,500 as per data released by the National Institutes of Health (NIH). As per data released by the National Organization for Rare Disorders (NORD), the early symptoms of hereditary neuropathy develop gradually sometime in adolescence, early adulthood or middle age and tends to affect an equal number of males and females. Among the European countries, Germany had the highest prevalent population of CMT with 30,000 cases, followed by France which had prevalent population of 23,414 in 2016. On the other hand, Spain had the lowest diagnosed prevalent population of 16,255 in 2016.
According to DelveInsight, total prevalent population of CMT in the 7 major markets estimated approximately 2, 56,934 cases in 2016.
DelveInsight estimates that the prevalent population of CMT in 7MM will significantly change during the study period [2016-2027].
DelveInsight estimates suggest higher prevalence of Charcot Marie Tooth (CMT) in the United States with 129,251 cases in 2016.
Charcot Marie Tooth Drug Chapters
This segment of the Charcot Marie Tooth (CMT) report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.
At present, there are no FDA approved therapies for the treatment of Charcot Marie Tooth (CMT) in the United States and the current therapeutic market for Charcot Marie Tooth (CMT) is based on the supportive management such as occupational therapies, physiotherapy, ankle-foot orthoses (AFO) and shoe inserts.
The expected launch of upcoming therapies such as PXT3003 (Pharnext) and ACE-083 (Acceleron) in 2021 and 2023 respectively have the potential to create a significant positive shift in the Charcot Marie Tooth (CMT) market size.
PXT3003 trial results indicated significant improvement in patients with mild-to-moderate CMT1A and provided encouraging results that indicate PXT3003 may change the treatment paradigm for the disease. Additionally, the candidate has also received Orphan Drug Status from the US FDA and EMA.
The other emerging therapy ACE-083 (Acceleron) is currently under development for the treatment of focal muscle loss. It has been designed to increase strength and function in specific target muscles for improved patient function and quality of life. It is currently under second phase of development for CMT and is also scheduled to enter the market within the forecast period [2018-2027].
Charcot Marie Tooth (CMT) Market Outlook
The Charcot Marie Tooth (CMT) market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria’s, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the market of Charcot Marie Tooth (CMT) in 7MM was found to be USD 502.75 million in 2016, and is expected to increase from 2016-2027.
The United States accounts for the largest market size of Charcot Marie Tooth (CMT), in comparison to EU5 (the United Kingdom, Germany, Italy, France, and Spain) and Japan.
Charcot Marie Tooth (CMT) Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2016-2027. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Charcot Marie Tooth (CMT) Report Insights
DelveInsight’s Charcot Marie Tooth (CMT) - Market Insights, Epidemiology and Market Forecast-2027’ report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Charcot Marie Tooth (CMT) in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom) and Japan.
The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Charcot Marie Tooth (CMT) from 2016 to 2027 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.
Geography Covered
- The United States
- EU5 (Germany, France, Italy, Spain and the United Kingdom)
- Japan
Charcot Marie Tooth - Disease Understanding and Treatment Algorithm
According to Charcot-Marie-Tooth Association (CMTA), CMT is a disease of the peripheral nerves that control muscles (unlike the muscular dystrophies, which affect the muscles themselves).It is a group of genetically heterogeneous disorders which affect the motor and/or sensory peripheral nerves, resulting in muscle weakness and atrophy in addition to sensory loss.
The many different types of Charcot Marie Tooth (CMT) are distinguished by age of onset, inheritance pattern, severity, and whether they're linked to defects in axon or myelin. Charcot Marie Tooth (CMT) can be divided into types and subtypes. The types are the clinical pictures of Charcot Marie Tooth (CMT) (CMT type 1, 2, 4, X, etc.), are usually defined by inheritance pattern and nerve conductions. Subtypes (CMT1A, 2B, 4C, X1, etc.) are given only when the genetic cause is known.
The exact symptoms of Charcot Marie Tooth (CMT) vary from person to person partly because there are different types of CMT. It may cause muscle weakness, contractures and bone deformities, sensory loss.
The DelveInsight Charcot Marie Tooth (CMT) market report gives the thorough understanding of the CMT by including details such as disease definition, symptoms, types, causes, genetics and inheritance, pathophysiology, and diagnosis. It also provides treatment algorithms and treatment guidelines for Charcot Marie Tooth (CMT) in the US, Europe, and Japan.
Charcot Marie Tooth Epidemiology
The Charcot Marie Tooth (CMT) epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology [segmented as Total Prevalent Population of Charcot Marie Tooth (CMT), Type Specific Prevalent Population of Charcot Marie Tooth (CMT) and Diagnosed Cases of Charcot Marie Tooth (CMT)] scenario of CMT in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom), and Japan from 2016-2027.
Charcot Marie Tooth (CMT) is one of the most commonly inherited neuropathy in the United States with an estimated prevalence of one in 2,500 as per data released by the National Institutes of Health (NIH). As per data released by the National Organization for Rare Disorders (NORD), the early symptoms of hereditary neuropathy develop gradually sometime in adolescence, early adulthood or middle age and tends to affect an equal number of males and females. Among the European countries, Germany had the highest prevalent population of CMT with 30,000 cases, followed by France which had prevalent population of 23,414 in 2016. On the other hand, Spain had the lowest diagnosed prevalent population of 16,255 in 2016.
According to DelveInsight, total prevalent population of CMT in the 7 major markets estimated approximately 2, 56,934 cases in 2016.
DelveInsight estimates that the prevalent population of CMT in 7MM will significantly change during the study period [2016-2027].
DelveInsight estimates suggest higher prevalence of Charcot Marie Tooth (CMT) in the United States with 129,251 cases in 2016.
Charcot Marie Tooth Drug Chapters
This segment of the Charcot Marie Tooth (CMT) report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.
At present, there are no FDA approved therapies for the treatment of Charcot Marie Tooth (CMT) in the United States and the current therapeutic market for Charcot Marie Tooth (CMT) is based on the supportive management such as occupational therapies, physiotherapy, ankle-foot orthoses (AFO) and shoe inserts.
The expected launch of upcoming therapies such as PXT3003 (Pharnext) and ACE-083 (Acceleron) in 2021 and 2023 respectively have the potential to create a significant positive shift in the Charcot Marie Tooth (CMT) market size.
PXT3003 trial results indicated significant improvement in patients with mild-to-moderate CMT1A and provided encouraging results that indicate PXT3003 may change the treatment paradigm for the disease. Additionally, the candidate has also received Orphan Drug Status from the US FDA and EMA.
The other emerging therapy ACE-083 (Acceleron) is currently under development for the treatment of focal muscle loss. It has been designed to increase strength and function in specific target muscles for improved patient function and quality of life. It is currently under second phase of development for CMT and is also scheduled to enter the market within the forecast period [2018-2027].
Charcot Marie Tooth (CMT) Market Outlook
The Charcot Marie Tooth (CMT) market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria’s, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the market of Charcot Marie Tooth (CMT) in 7MM was found to be USD 502.75 million in 2016, and is expected to increase from 2016-2027.
The United States accounts for the largest market size of Charcot Marie Tooth (CMT), in comparison to EU5 (the United Kingdom, Germany, Italy, France, and Spain) and Japan.
Charcot Marie Tooth (CMT) Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2016-2027. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Charcot Marie Tooth (CMT) Report Insights
- Patient Population
- Therapeutic Approaches
- Pipeline Analysis
- Market Size and Trends
- Market Opportunities
- Impact of upcoming Therapies
- 10 Years Forecast
- 7MM Coverage
- Epidemiology Segmentation
- Key Cross Competition
- Highly Analyzed Market
- Drugs Uptake
- Current Treatment Practices
- Unmet Needs
- Pipeline Product Profiles
- Market Attractiveness
- Market Drivers and Barriers
- This DelveInsight report will help to develop Business Strategies by understanding the trends shaping and driving Charcot Marie Tooth (CMT) market
- Organize sales and marketing efforts by identifying the best opportunities for Charcot Marie Tooth (CMT) market
- To understand the future market competition in the Charcot Marie Tooth (CMT) market.
1. KEY INSIGHTS
2. CHARCOT MARIE TOOTH MARKET OVERVIEW AT A GLANCE
2.1. Market Share (%) Distribution of Charcot Marie Tooth (CMT) in 2016
2.2. Market Share (%) Distribution of Charcot Marie Tooth (CMT) in 2027
3. CHARCOT MARIE TOOTH (CMT): DISEASE BACKGROUND AND OVERVIEW
3.1. Introduction
3.2. Symptoms
3.3. Types of Charcot Marie Tooth
3.4. Causes
3.5. Genetics and Inheritance
3.5.1. Autosomal Dominant Inheritance
3.5.2. Autosomal Recessive Inheritance
3.5.3. X-Linked Inheritance
3.5.4. Spontaneous Mutation
3.6. Pathophysiology
3.7. Diagnosis
4. EPIDEMIOLOGY AND PATIENT POPULATION
4.1. Key Findings
5. 7MM TOTAL PREVALENT POPULATION OF CHARCOT MARIE TOOTH
6. COUNTRY WISE-EPIDEMIOLOGY OF CHARCOT MARIE TOOTH
6.1. United States
6.1.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in the United States
6.1.2. Type Specific Prevalent Population of Charcot Marie Tooth (CMT) in the United States
6.1.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in the US
6.2. EU5 Countries
6.3. Germany
6.3.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Germany
6.3.2. Type Specific Diagnosed Prevalence of Charcot Marie Tooth (CMT) in Germany
6.3.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Germany
6.4. France
6.4.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in France
6.4.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in France
6.4.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in France
6.5. Italy
6.5.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Italy
6.5.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in Italy
6.5.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Italy
6.6. Spain
6.6.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Spain
6.6.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in Spain
6.6.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Spain
6.7. United Kingdom
6.7.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in the United Kingdom
6.7.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in UK
6.7.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in UK
6.8. Japan
6.8.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Japan
6.8.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in Japan
6.8.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Japan
7. TREATMENT
8. UNMET NEEDS
9. EMERGING DRUGS
9.1. Key Cross Competition
9.2. PXT3003: Pharnext
9.2.1. Product Description
9.2.2. Other Developmental Activities
9.2.3. Clinical Development
9.2.4. Safety and Efficacy
9.2.5. Advantages and Disadvantages
9.2.6. Product Profile
9.3. ACE-083: Acceleron Pharma
9.3.1. Product Description
9.3.2. Other Development Activities
9.3.3. Clinical Development
9.3.4. Safety and Efficacy
9.3.5. Advantages and Disadvantages
9.3.6. Product Profile
9.4. MD1003: MedDay Pharmaceuticals
9.4.1. Product Description
9.4.2. Other Development Activities
9.4.3. Clinical Development
9.4.4. Product Profile
10. CHARCOT MARIE TOOTH (CMT): 7 MAJOR MARKET ANALYSIS
10.1. Key Findings
10.2. Market Size of Charcot Marie Tooth in 7MM
11. THE UNITED STATES MARKET OUTLOOK
11.1. United States Market Size
11.1.1. Total Market size of Charcot Marie Tooth (CMT)
11.1.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in the US
12. EU-5 COUNTRIES: MARKET OUTLOOK
12.1. Germany
12.1.1. Total Market size of Charcot Marie Tooth (CMT) in Germany
12.1.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in Germany
12.2. France
12.2.1. Total Market size of Charcot Marie Tooth (CMT) in France
12.2.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in France
12.3. Italy
12.3.1. Total Market size of Charcot Marie Tooth (CMT) in Italy
12.3.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in Italy
12.4. Spain
12.4.1. Total Market size of Charcot Marie Tooth (CMT) in Spain
12.4.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in Spain
12.5. United Kingdom
12.5.1. Total Market size of Charcot Marie Tooth (CMT) in UK
12.5.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in UK
12.6. Japan: Market Outlook
12.7. Total Market size of Charcot Marie Tooth (CMT) in Japan
12.8. Market Size of Charcot Marie Tooth (CMT) by Therapies in Japan
13. MARKET DRIVERS
14. MARKET BARRIERS
15. APPENDIX
15.1. Report Methodology
16. DELVEINSIGHT CAPABILITIES
17. DISCLAIMER
18. ABOUT DELVEINSIGHT
2. CHARCOT MARIE TOOTH MARKET OVERVIEW AT A GLANCE
2.1. Market Share (%) Distribution of Charcot Marie Tooth (CMT) in 2016
2.2. Market Share (%) Distribution of Charcot Marie Tooth (CMT) in 2027
3. CHARCOT MARIE TOOTH (CMT): DISEASE BACKGROUND AND OVERVIEW
3.1. Introduction
3.2. Symptoms
3.3. Types of Charcot Marie Tooth
3.4. Causes
3.5. Genetics and Inheritance
3.5.1. Autosomal Dominant Inheritance
3.5.2. Autosomal Recessive Inheritance
3.5.3. X-Linked Inheritance
3.5.4. Spontaneous Mutation
3.6. Pathophysiology
3.7. Diagnosis
4. EPIDEMIOLOGY AND PATIENT POPULATION
4.1. Key Findings
5. 7MM TOTAL PREVALENT POPULATION OF CHARCOT MARIE TOOTH
6. COUNTRY WISE-EPIDEMIOLOGY OF CHARCOT MARIE TOOTH
6.1. United States
6.1.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in the United States
6.1.2. Type Specific Prevalent Population of Charcot Marie Tooth (CMT) in the United States
6.1.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in the US
6.2. EU5 Countries
6.3. Germany
6.3.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Germany
6.3.2. Type Specific Diagnosed Prevalence of Charcot Marie Tooth (CMT) in Germany
6.3.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Germany
6.4. France
6.4.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in France
6.4.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in France
6.4.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in France
6.5. Italy
6.5.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Italy
6.5.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in Italy
6.5.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Italy
6.6. Spain
6.6.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Spain
6.6.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in Spain
6.6.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Spain
6.7. United Kingdom
6.7.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in the United Kingdom
6.7.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in UK
6.7.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in UK
6.8. Japan
6.8.1. Total Prevalent Population of Charcot Marie Tooth (CMT) in Japan
6.8.2. Type Specific Prevalence of Charcot Marie Tooth (CMT) in Japan
6.8.3. Diagnosed Cases of Charcot Marie Tooth (CMT) in Japan
7. TREATMENT
8. UNMET NEEDS
9. EMERGING DRUGS
9.1. Key Cross Competition
9.2. PXT3003: Pharnext
9.2.1. Product Description
9.2.2. Other Developmental Activities
9.2.3. Clinical Development
9.2.4. Safety and Efficacy
9.2.5. Advantages and Disadvantages
9.2.6. Product Profile
9.3. ACE-083: Acceleron Pharma
9.3.1. Product Description
9.3.2. Other Development Activities
9.3.3. Clinical Development
9.3.4. Safety and Efficacy
9.3.5. Advantages and Disadvantages
9.3.6. Product Profile
9.4. MD1003: MedDay Pharmaceuticals
9.4.1. Product Description
9.4.2. Other Development Activities
9.4.3. Clinical Development
9.4.4. Product Profile
10. CHARCOT MARIE TOOTH (CMT): 7 MAJOR MARKET ANALYSIS
10.1. Key Findings
10.2. Market Size of Charcot Marie Tooth in 7MM
11. THE UNITED STATES MARKET OUTLOOK
11.1. United States Market Size
11.1.1. Total Market size of Charcot Marie Tooth (CMT)
11.1.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in the US
12. EU-5 COUNTRIES: MARKET OUTLOOK
12.1. Germany
12.1.1. Total Market size of Charcot Marie Tooth (CMT) in Germany
12.1.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in Germany
12.2. France
12.2.1. Total Market size of Charcot Marie Tooth (CMT) in France
12.2.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in France
12.3. Italy
12.3.1. Total Market size of Charcot Marie Tooth (CMT) in Italy
12.3.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in Italy
12.4. Spain
12.4.1. Total Market size of Charcot Marie Tooth (CMT) in Spain
12.4.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in Spain
12.5. United Kingdom
12.5.1. Total Market size of Charcot Marie Tooth (CMT) in UK
12.5.2. Market Size of Charcot Marie Tooth (CMT) by Therapies in UK
12.6. Japan: Market Outlook
12.7. Total Market size of Charcot Marie Tooth (CMT) in Japan
12.8. Market Size of Charcot Marie Tooth (CMT) by Therapies in Japan
13. MARKET DRIVERS
14. MARKET BARRIERS
15. APPENDIX
15.1. Report Methodology
16. DELVEINSIGHT CAPABILITIES
17. DISCLAIMER
18. ABOUT DELVEINSIGHT
LIST OF TABLES
Table 1: Characteristics of Charcot Marie Tooth (CMT) Subtypes
Table 2: Multidisciplinary members and roles in the diagnosis and management of CMT
Table 3: Molecular Diagnostic Methods to Detect CMT1A Duplication/HNPP Deletion
Table 4: CMT classification, including clinical data (such as electrophysiological results) and molecular findings
Table 5: Total Prevalent Population of Charcot Marie Tooth (CMT) in the 7MM (2016-2027)
Table 6: Total Prevalent Population of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Table 7: Type Specific Prevalence of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Table 8: Diagnosed Cases of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Table 9: Total Prevalent Population of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Table 10: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Table 11: Diagnosed Cases of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Table 12: Total Prevalent Population of Charcot Marie Tooth (CMT) in France (2016-2027)
Table 13: Type Specific Prevalence of Charcot Marie Tooth (CMT) in France (2016-2027)
Table 14: Diagnosed Cases of Charcot Marie Tooth (CMT) in France (2016-2027)
Table 15: Total Prevalent Population of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Table 16: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Table 17: Diagnosed Cases of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Table 18: Total Prevalent Population of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Table 19: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Table 20: Diagnosed Cases of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Table 21: Total Prevalent Population of Charcot Marie Tooth (CMT) in the UK (2016-2027)
Table 22: Type Specific Prevalence of Charcot Marie Tooth (CMT) in UK (2016-2027)
Table 23: Diagnosed Cases of Charcot Marie Tooth (CMT) in the UK (2016-2027)
Table 24: Total Prevalent Population of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Table 25: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Table 26: Diagnosed Cases of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Table 27: Comparison of emerging drugs under development
Table 28: PXT3003, Clinical Trial Description, 2017
Table 29: ACE-083, Clinical Trial Description, 2017
Table 30: MD1003, Clinical Trial Description, 2018
Table 31: 7 Major Market Size of Charcot Marie Tooth (CMT) in USD Million (2016-2027)
Table 32: 7 Major Market Size of Charcot Marie Tooth (CMT) by therapies in USD Million (2016-2027)
Table 33: United States Market Size of Charcot Marie Tooth (CMT) in USD Million (2016-2027)
Table 34:Market size of Charcot Marie Tooth (CMT) by therapies in United States, in USD Million (2016-2027)
Table 35: Market Size of Charcot Marie Tooth (CMT) in Germany, in USD Million (2016-2027)
Table 36:Market size of Charcot Marie Tooth (CMT) by therapies in Germany, in USD Million (2016-2027)
Table 37: Market Size of Charcot Marie Tooth (CMT) in France, in USD Million (2016-2027)
Table 38:Market size of Charcot Marie Tooth (CMT) by therapies in France, in USD Million (2016-2027)
Table 39: Market Size of Charcot Marie Tooth (CMT) in the Italy, in USD Million (2016-2027)
Table 40: Market size of Charcot Marie Tooth (CMT) by therapies in Italy, in USD Million (2016-2027)
Table 41: Market Size of Charcot Marie Tooth (CMT) in Spain, in USD Million (2016-2027)
Table 42:Market size of Charcot Marie Tooth (CMT) by therapies in Spain, in USD Million (2016-2027)
Table 43: Market Size of Charcot Marie Tooth (CMT) in the UK, in USD Million (2016-2027)
Table 44: Market size of Charcot Marie Tooth (CMT) by therapies in UK, in USD Million (2016-2027)
Table 45: Market Size of Charcot Marie Tooth (CMT) in Japan, in USD Million (2016-2027)
Table 46:Market size of Charcot Marie Tooth (CMT) by therapies in Japan, in USD Million (2016-2027)
Table 1: Characteristics of Charcot Marie Tooth (CMT) Subtypes
Table 2: Multidisciplinary members and roles in the diagnosis and management of CMT
Table 3: Molecular Diagnostic Methods to Detect CMT1A Duplication/HNPP Deletion
Table 4: CMT classification, including clinical data (such as electrophysiological results) and molecular findings
Table 5: Total Prevalent Population of Charcot Marie Tooth (CMT) in the 7MM (2016-2027)
Table 6: Total Prevalent Population of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Table 7: Type Specific Prevalence of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Table 8: Diagnosed Cases of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Table 9: Total Prevalent Population of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Table 10: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Table 11: Diagnosed Cases of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Table 12: Total Prevalent Population of Charcot Marie Tooth (CMT) in France (2016-2027)
Table 13: Type Specific Prevalence of Charcot Marie Tooth (CMT) in France (2016-2027)
Table 14: Diagnosed Cases of Charcot Marie Tooth (CMT) in France (2016-2027)
Table 15: Total Prevalent Population of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Table 16: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Table 17: Diagnosed Cases of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Table 18: Total Prevalent Population of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Table 19: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Table 20: Diagnosed Cases of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Table 21: Total Prevalent Population of Charcot Marie Tooth (CMT) in the UK (2016-2027)
Table 22: Type Specific Prevalence of Charcot Marie Tooth (CMT) in UK (2016-2027)
Table 23: Diagnosed Cases of Charcot Marie Tooth (CMT) in the UK (2016-2027)
Table 24: Total Prevalent Population of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Table 25: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Table 26: Diagnosed Cases of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Table 27: Comparison of emerging drugs under development
Table 28: PXT3003, Clinical Trial Description, 2017
Table 29: ACE-083, Clinical Trial Description, 2017
Table 30: MD1003, Clinical Trial Description, 2018
Table 31: 7 Major Market Size of Charcot Marie Tooth (CMT) in USD Million (2016-2027)
Table 32: 7 Major Market Size of Charcot Marie Tooth (CMT) by therapies in USD Million (2016-2027)
Table 33: United States Market Size of Charcot Marie Tooth (CMT) in USD Million (2016-2027)
Table 34:Market size of Charcot Marie Tooth (CMT) by therapies in United States, in USD Million (2016-2027)
Table 35: Market Size of Charcot Marie Tooth (CMT) in Germany, in USD Million (2016-2027)
Table 36:Market size of Charcot Marie Tooth (CMT) by therapies in Germany, in USD Million (2016-2027)
Table 37: Market Size of Charcot Marie Tooth (CMT) in France, in USD Million (2016-2027)
Table 38:Market size of Charcot Marie Tooth (CMT) by therapies in France, in USD Million (2016-2027)
Table 39: Market Size of Charcot Marie Tooth (CMT) in the Italy, in USD Million (2016-2027)
Table 40: Market size of Charcot Marie Tooth (CMT) by therapies in Italy, in USD Million (2016-2027)
Table 41: Market Size of Charcot Marie Tooth (CMT) in Spain, in USD Million (2016-2027)
Table 42:Market size of Charcot Marie Tooth (CMT) by therapies in Spain, in USD Million (2016-2027)
Table 43: Market Size of Charcot Marie Tooth (CMT) in the UK, in USD Million (2016-2027)
Table 44: Market size of Charcot Marie Tooth (CMT) by therapies in UK, in USD Million (2016-2027)
Table 45: Market Size of Charcot Marie Tooth (CMT) in Japan, in USD Million (2016-2027)
Table 46:Market size of Charcot Marie Tooth (CMT) by therapies in Japan, in USD Million (2016-2027)
LIST OF FIGURES
Figure 1: Patients with Charcot–Marie–Tooth (CMT) Disease
Figure 2: Different forms of Charcot–Marie–Tooth (CMT) disease and associated genes
Figure 3: Different forms of Charcot–Marie–Tooth (CMT) disease
Figure 4: Schematic overview highlighting proteins that are mutated in Charcot Marie Tooth (CMT)
Figure 5: Total Prevalent Population of Charcot Marie Tooth (CMT) in the 7MM (2016-2027)
Figure 6: Total Prevalence of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Figure 7: Type Specific Prevalence of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Figure 8: Diagnosed Cases of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Figure 9: Total Prevalent Population of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Figure 10: Type Specific Diagnosed Prevalence of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Figure 11: Diagnosed Cases of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Figure 12: Total Prevalent Population of Charcot Marie Tooth (CMT) in France (2016-2027)
Figure 13: Type Specific Prevalence of Charcot Marie Tooth (CMT) in France (2016-2027)
Figure 14: Diagnosed Cases of Charcot Marie Tooth (CMT) in France (2016-2027)
Figure 15: Total Prevalent Population of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Figure 16: Type Specific Diagnosed Prevalence of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Figure 17: Diagnosed Cases of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Figure 18: Total Prevalent Population of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Figure 19: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Figure 20: Diagnosed Cases of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Figure 21: Total Prevalent Population of Charcot Marie Tooth (CMT) in the UK (2016-2027)
Figure 22: Type Specific Prevalence of Charcot Marie Tooth (CMT) in the United Kingdom (2016-2027)
Figure 23: Diagnosed Cases of Charcot Marie Tooth (CMT) in UK (2016-2027)
Figure 24: Total Prevalent Population of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Figure 25: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Figure 26: Diagnosed Cases of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Figure 27: Unmet Needs of Charcot Marie Tooth (CMT) Disease
Figure 28: 7 Major Market Size of Charcot Marie Tooth (CMT) in USD Million (2016-2027)
Figure 29: 7 Major Market Size of Charcot Marie Tooth (CMT) by therapies in USD Million (2016-2027)
Figure 30: Market Size of Charcot Marie Tooth (CMT) in the United States, USD Millions (2016-2027)
Figure 31: Market size of Charcot Marie Tooth (CMT) by therapies in the US, in USD Million (2016-2027)
Figure 32: Market Size of Charcot Marie Tooth (CMT) in Germany, USD Millions (2016-2027)
Figure 33: Market Size of Charcot Marie Tooth (CMT) by therapies, in Germany, in USD Million (2016-2027)
Figure 34: Market Size of Charcot Marie Tooth (CMT) in France, USD Millions (2016-2027)
Figure 35: Market Size of Charcot Marie Tooth (CMT) by therapies, in France, in USD Million (2016-2027)
Figure 36: Market Size of Charcot Marie Tooth (CMT) in the Italy, USD Millions (2016-2027)
Figure 37: Market Size of Charcot Marie Tooth (CMT) by therapies in Italy, in USD Million (2016-2027)
Figure 38: Market Size of Charcot Marie Tooth (CMT) in Spain, USD Millions (2016-2027)
Figure 39: Market Size of Charcot Marie Tooth (CMT) by therapies in Spain, in USD Million (2016-2027)
Figure 40: Market Size of Charcot Marie Tooth (CMT) in the UK, USD Millions (2016-2027)
Figure 41: Market Size of Charcot Marie Tooth (CMT) by therapies in the UK, in USD Million (2016-2027)
Figure 42: Market Size of Charcot Marie Tooth (CMT) in Japan, USD Millions (2016-2027)
Figure 43: Market Size of Charcot Marie Tooth (CMT) by therapies in Japan, in USD Million (2016-2027)
Figure 44: Market Drivers
Figure 45:Market Barriers
Figure 1: Patients with Charcot–Marie–Tooth (CMT) Disease
Figure 2: Different forms of Charcot–Marie–Tooth (CMT) disease and associated genes
Figure 3: Different forms of Charcot–Marie–Tooth (CMT) disease
Figure 4: Schematic overview highlighting proteins that are mutated in Charcot Marie Tooth (CMT)
Figure 5: Total Prevalent Population of Charcot Marie Tooth (CMT) in the 7MM (2016-2027)
Figure 6: Total Prevalence of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Figure 7: Type Specific Prevalence of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Figure 8: Diagnosed Cases of Charcot Marie Tooth (CMT) in the United States (2016-2027)
Figure 9: Total Prevalent Population of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Figure 10: Type Specific Diagnosed Prevalence of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Figure 11: Diagnosed Cases of Charcot Marie Tooth (CMT) in Germany (2016-2027)
Figure 12: Total Prevalent Population of Charcot Marie Tooth (CMT) in France (2016-2027)
Figure 13: Type Specific Prevalence of Charcot Marie Tooth (CMT) in France (2016-2027)
Figure 14: Diagnosed Cases of Charcot Marie Tooth (CMT) in France (2016-2027)
Figure 15: Total Prevalent Population of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Figure 16: Type Specific Diagnosed Prevalence of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Figure 17: Diagnosed Cases of Charcot Marie Tooth (CMT) in Italy (2016-2027)
Figure 18: Total Prevalent Population of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Figure 19: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Figure 20: Diagnosed Cases of Charcot Marie Tooth (CMT) in Spain (2016-2027)
Figure 21: Total Prevalent Population of Charcot Marie Tooth (CMT) in the UK (2016-2027)
Figure 22: Type Specific Prevalence of Charcot Marie Tooth (CMT) in the United Kingdom (2016-2027)
Figure 23: Diagnosed Cases of Charcot Marie Tooth (CMT) in UK (2016-2027)
Figure 24: Total Prevalent Population of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Figure 25: Type Specific Prevalence of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Figure 26: Diagnosed Cases of Charcot Marie Tooth (CMT) in Japan (2016-2027)
Figure 27: Unmet Needs of Charcot Marie Tooth (CMT) Disease
Figure 28: 7 Major Market Size of Charcot Marie Tooth (CMT) in USD Million (2016-2027)
Figure 29: 7 Major Market Size of Charcot Marie Tooth (CMT) by therapies in USD Million (2016-2027)
Figure 30: Market Size of Charcot Marie Tooth (CMT) in the United States, USD Millions (2016-2027)
Figure 31: Market size of Charcot Marie Tooth (CMT) by therapies in the US, in USD Million (2016-2027)
Figure 32: Market Size of Charcot Marie Tooth (CMT) in Germany, USD Millions (2016-2027)
Figure 33: Market Size of Charcot Marie Tooth (CMT) by therapies, in Germany, in USD Million (2016-2027)
Figure 34: Market Size of Charcot Marie Tooth (CMT) in France, USD Millions (2016-2027)
Figure 35: Market Size of Charcot Marie Tooth (CMT) by therapies, in France, in USD Million (2016-2027)
Figure 36: Market Size of Charcot Marie Tooth (CMT) in the Italy, USD Millions (2016-2027)
Figure 37: Market Size of Charcot Marie Tooth (CMT) by therapies in Italy, in USD Million (2016-2027)
Figure 38: Market Size of Charcot Marie Tooth (CMT) in Spain, USD Millions (2016-2027)
Figure 39: Market Size of Charcot Marie Tooth (CMT) by therapies in Spain, in USD Million (2016-2027)
Figure 40: Market Size of Charcot Marie Tooth (CMT) in the UK, USD Millions (2016-2027)
Figure 41: Market Size of Charcot Marie Tooth (CMT) by therapies in the UK, in USD Million (2016-2027)
Figure 42: Market Size of Charcot Marie Tooth (CMT) in Japan, USD Millions (2016-2027)
Figure 43: Market Size of Charcot Marie Tooth (CMT) by therapies in Japan, in USD Million (2016-2027)
Figure 44: Market Drivers
Figure 45:Market Barriers
