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Cervical cancer - Pipeline Insight, 2021

July 2021 | 60 pages | ID: C88E57AB25A2EN
DelveInsight

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DelveInsight’s, “Cervical cancer - Pipeline Insight, 2021,” report provides comprehensive insights about 70+ companies and 70+ pipeline drugs in Cervical cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Cervical cancer Understanding

Cervical cancer: Overview

Cervical cancer develops in a woman's cervix (the entrance to the uterus from the vagina). Almost all Cervical cancer cases (99%) are linked to infection with high-risk human papillomaviruses (HPV), an extremely common virus transmitted through sexual contact. Although most infections with HPV resolve spontaneously and cause no symptoms, persistent infection can cause Cervical cancer in women. Cervical cancer is the fourth most common cancer in women. In 2018, an estimated 570 000 women were diagnosed with Cervical cancer worldwide and about 311 000 women died from the disease. Effective primary (HPV vaccination) and secondary prevention approaches (screening for, and treating precancerous lesions) will prevent most Cervical cancer cases. When diagnosed, Cervical cancer is one of the most successfully treatable forms of cancer, as long as it is detected early and managed effectively. Cancers diagnosed in late stages can also be controlled with appropriate treatment and palliative care.

'Cervical cancer - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Cervical cancer pipeline landscape is provided which includes the disease overview and Cervical cancer treatment guidelines. The assessment part of the report embraces, in depth Cervical cancer commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Cervical cancer collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Cervical cancer R&D. The therapies under development are focused on novel approaches to treat/improve Cervical cancer.
Cervical cancer Emerging Drugs Chapters

This segment of the Cervical cancer report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Cervical cancer Emerging Drugs
  • Cemiplimab: Regeneron Pharmaceuticals
Cemiplimab (Libtayo) is a fully-human monoclonal antibody targeting the immune checkpoint receptor PD-1 on T-cells. By binding to PD-1, Libtayo has been shown to block cancer cells from using the PD-1 pathway to suppress T-cell activation. Currently, it is in Phase III stage of development to treat Cervical cancer.
  • AK104: Akesobio
AK104 is a potential next-generation, first-in-class humanized IgG1 tetrameric bi-specific antibody drug candidate that is based on Akeso’s proprietary “TETRABODY” technology and simultaneously targets two immune checkpoint molecules: PD-1 and CTLA-4. AK104 is in a tetrameric form, which is designed to bind to PD-1 and CTLA-4 simultaneously to achieve the efficacy of PD-1 and CTLA-4 combination blockade with lower toxicity.
  • Durvalumab: Celgene
Durvalumab is an investigational human monoclonal antibody directed against programmed death ligand-1 (PD-L1). Signals from PD-L1 help tumours avoid detection by the immune system. Durvalumab blocks these signals, countering the tumour's immune-evading tactics. Durvalumab is being investigated in an extensive clinical trial programme, as monotherapy or in combination in multiple cancer types. Currently, it is in Phase III stage of development to treat Cervical cancer.

Further product details are provided in the report……..

Cervical cancer: Therapeutic Assessment

This segment of the report provides insights about the different Cervical cancer drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Cervical cancer
There are approx. 70+ key companies which are developing the therapies for Cervical cancer. The companies which have their Cervical cancer drug candidates in the most advanced stage, i.e. phase III include, Regeneron Pharmaceuticals.
  • Phases
DelveInsight’s report covers around 70+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Cervical cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • intravenous
  • Subcutaneous
  • Topical.
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Cervical cancer: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Cervical cancer therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Cervical cancer drugs.

Cervical cancer Report Insights
  • Cervical cancer Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Cervical cancer Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Cervical cancer drugs?
  • How many Cervical cancer drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Cervical cancer?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Cervical cancer therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Cervical cancer and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • Regeneron Pharmaceuticals
  • Akesobio
  • Celgene
  • AstraZeneca
  • ImaginAb Inc
  • Genexine, Inc.
  • Merck KGaA
  • Seagen Inc.
  • Vaccibody AS
  • Qilu Pharmaceutical Co., Ltd.
  • Genor Biopharma Co., Ltd.
  • Agenus Inc.
  • Immunitor LLC
  • Genentech
  • Guangzhou Gloria Biosciences Co., Ltd.
  • Lee's Pharmaceutical Limited
  • BeiGene
  • Henlix Biotech
  • Biocad
  • CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
  • Cellid Co., Ltd.
  • Innovent Biologics
  • Zeria Pharmaceutical
  • Advaxis, Inc.
  • Human Genome Sciences
  • Hookipa Biotech GmbH
  • Eli Lilly and Company
  • SK Bioscience Co., Ltd.
  • Tesaro, Inc
  • Iovance Biotherapeutics, Inc.
  • NETRIS Pharma
  • Advenchen Laboratories, LLC
  • Rubius Therapeutics
  • Repertoire Immune Medicines
  • Bristol-Myers Squibb
  • Sotio a.s.
  • VM Oncology, LLC
  • Andes Biotechnologies
  • Transgene
  • Xencor, Inc.
  • Exelixis
  • Ocellaris Pharma, Inc
  • Fate Therapeutics
  • Arcus Biosciences, Inc.
  • MacroGenics
Key Products
  • Cemiplimab
  • AK104
  • Durvalumab
  • MEDI 0457
  • 89Zr Df IAB 22M2C
  • GX-188E
  • M7824
  • Tisotumab Vedotin
  • VB10.16
  • QL1604
  • GB226
  • AGEN2034
  • V3-Cervix
  • Tiragolumab
  • GLS-010
  • ZKAB001
  • Tislelizumab
  • HLX10
  • BCD-100
  • SG001
  • BVAC-C
  • IBI310
  • Z-100
  • ADXS11-001
  • Mapatumumab
  • HB-201
  • Gemzar
  • NBP615
  • Niraparib
  • LN-145
  • NP137
  • AL3818
  • RTX-321
  • RPTR-168
  • BMS-986340
  • SO-C101
  • VMD-928
  • Andes-1537
  • TG4001
  • XmAb®23104
  • XB002
  • OC-001
  • FT 500
  • AB308
  • MGD013
Introduction
Executive Summary
Cervical cancer: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
  Comparative Analysis
Cemiplimab: Regeneron Pharmaceuticals
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  Comparative Analysis
AK104: Akeso Biopharma
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..

Early Stage Products (Phase I/II)
  Comparative Analysis
TG4001: Transgene
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
  Comparative Analysis
IMGN 151: ImmunoGen
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report…..

Inactive Products
  Comparative Analysis
Cervical cancer Key Companies
Cervical cancer Key Products
Cervical cancer- Unmet Needs
Cervical cancer- Market Drivers and Barriers
Cervical cancer- Future Perspectives and Conclusion
Cervical cancer Analyst Views
Cervical cancer Key Companies
Appendix


LIST OF TABLES

Table 1 Total Products for Cervical cancer
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products


LIST OF FIGURES

Figure 1 Total Products for Cervical cancer
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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