[email protected] +44 20 8123 2220 (UK) +1 732 587 5005 (US) Contact Us | FAQ |

Cachexia - Pipeline Insight, 2021

June 2021 | 80 pages | ID: C691EFA840FEN
DelveInsight

US$ 2,000.00

E-mail Delivery (PDF)

Download PDF Leaflet

Accepted cards
Wire Transfer
Checkout Later
Need Help? Ask a Question
This report can be delivered to the clients within 72 Hours

DelveInsight’s, “Cachexia - Pipeline Insight, 2021,” report provides comprehensive insights about 22+ companies and 22+ pipeline drugs in Cachexia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Cachexia Understanding

Cachexia: Overview

Cachexia is a “wasting” disorder that causes extreme weight loss and muscle wasting, and can include loss of body fat. It is a symptom of many chronic conditions, such as cancer, chronic renal failure, HIV, and multiple sclerosis. The main symptoms of the conditions are severe weight loss, including loss of fat and muscle mass, loss of appetite, anemia (low red blood cells), weakness and fatigue. Cachexia adversely affects the patients’ ability to fight against infection and withstand treatment by chemotherapy and radiotherapy. The goal of treatment for cachexia is to improve symptoms and quality of life. Current therapy for cachexia includes: appetite stimulants such as megestrol acetate drugs, medications that decrease inflammation, diet changes, nutritional supplements and exercise.

'Cachexia - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Cachexia pipeline landscape is provided which includes the disease overview and Cachexia treatment guidelines. The assessment part of the report embraces, in depth Cachexia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Cachexia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Cachexia R&D. The therapies under development are focused on novel approaches to treat/improve Cachexia.
Cachexia Emerging Drugs Chapters

This segment of the Cachexia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Cachexia Emerging Drugs
  • GCWB 204: Green Cross Wellbeing
GCWB 204 (BST 204), a purified ginseng extract with reinforced ginsenosides Rh2 and Rg3. Green Cross Wellbeing is developing the drug as oral capsule in Phase II clinical studies for the treatment of cancer cachexia.
  • Ponsegromab: Pfizer
Ponsegromab (formerly PF-06946860) is subcutaneous, monoclonal antibody directed against the human growth differentiation factor 15 (GDF15; MIC-1). The drug is in Phase I clinical developmental studies for the treatment of Cachexia.

Further product details are provided in the report..

Cachexia: Therapeutic Assessment

This segment of the report provides insights about the different Cachexia drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Cachexia
There are approx. 22+ key companies which are developing the therapies for Cachexia. The companies which have their Cachexia drug candidates in the most advanced stage, i.e. Phase II include, Green Cross Wellbeing.
  • Phases
DelveInsight’s report covers around 22+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Cachexia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravitreal
  • Subretinal
  • Topical
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Cachexia: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Cachexia therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Cachexia drugs.

Cachexia Report Insights
  • Cachexia Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Cachexia Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Cachexia drugs?
  • How many Cachexia drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Cachexia?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Cachexia therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Cachexia and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • Incyte Corporation
  • Green Cross Wellbeing
  • AEterna Zentaris
  • AVEO Oncology
  • AstraZeneca
  • Endevica Bio
  • Actimed Therapeutics
  • Creative Medical Technology Holdings
  • Ildong Pharmaceutical
  • Immuneering
Key Products
  • Ruxolitinib
  • GCWB 204
  • Macimorelin
  • AV 380
  • ART 2713
  • TCMCB-07
  • ACM-002
  • Research programme: amniotic stem cell therapies
  • ID 11917
  • Research programme: cancer therapeutics
Introduction
Executive Summary
Cachexia: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Cachexia – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  Cachexia companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Cachexia Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
Drug name: Company name
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Mid Stage Products (Phase II)
  Comparative Analysis
GCWB 204: Green Cross Wellbeing
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Early Stage Products (Phase I)
  Comparative Analysis
Ponsegromab: Pfizer
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Preclinical/Discovery Stage Products
  Comparative Analysis
TCMCB-07: Endevica Bio
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Inactive Products
  Comparative Analysis
Cachexia Key Companies
Cachexia Key Products
Cachexia- Unmet Needs
Cachexia- Market Drivers and Barriers
Cachexia- Future Perspectives and Conclusion
Cachexia Analyst Views
Cachexia Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for Cachexia
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

LIST OF FIGURES

Figure 1 Total Products for Cachexia
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


More Publications