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BK Virus infections - Pipeline Insight, 2021

May 2021 | 60 pages | ID: B3F85F324B66EN
DelveInsight

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DelveInsight’s, “BK Virus infections – Pipeline Insight, 2021,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in BK Virus infections pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
BK Virus infections Understanding

BK Virus infections: Overview

The BK virus was first isolated from the urine of a renal transplant recipient with ureteric stenosis in 1971. The BK virus is a member of the polyomavirus family. The BK virus rarely causes disease but is typically associated with patients who have had a kidney transplant; many people who are infected with this virus are asymptomatic. If symptoms do appear, they tend to be mild: respiratory infection or fever. It is known, however, that the virus is spread from person to person, and not from an animal source. It has been suggested that this virus may be transmitted through respiratory fluids or urine, since infected individuals periodically excrete virus in the urine. This virus can be diagnosed by a BKV blood test or a urine test for decoy cells, in addition to carrying out a biopsy in the kidneys. PCR techniques are often carried out to identify the virus. Unfortunately, treatment options for BK virus infection are limited, and there is no effective prophylaxis.

'BK Virus infections - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the BK Virus infections pipeline landscape is provided which includes the disease overview and BK Virus infections treatment guidelines. The assessment part of the report embraces, in depth BK Virus infections commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, BK Virus infections collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence BK Virus infections R&D. The therapies under development are focused on novel approaches to treat/improve BK Virus infections.
BK Virus infections Emerging Drugs Chapters

This segment of the BK Virus infections report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

BK Virus infections Emerging Drugs
  • ALVR105 (Viralym-M): AlloVir
Viralym-M targets five devastating viral pathogens: BK virus (BKV), Cytomegalovirus (CMV), Adenovirus (AdV), Epstein - Barr virus (EBV), and Human Herpesvirus 6 (HHV-6), and has the potential to transform care for transplant recipients. Viralym-M is designed to play an important role in providing bridging immunity between conditioning and reconstitution of their immune systems. The drug is currently in Phase III stage of development for the treatment of patients with BK virus infections.
  • MAU868: Amplyx Pharmaceuticals
MAU868 is a potent neutralizing monoclonal antibody with activity against BKV. BKV reactivation can occur following kidney transplantation and may result in BKV nephropathy, a leading cause of renal allograft loss. Amplyx executed an exclusive worldwide license agreement with Novartis under which the company has acquired the rights to the Phase 2 anti-BK virus (BKV) monoclonal antibody, MAU868, for the treatment and prevention of BKV disease. The company is conducting Phase 2 proof-of-concept clinical trials of MAU868 in BKV disease.

Further product details are provided in the report

BK Virus infections: Therapeutic Assessment

This segment of the report provides insights about the different BK Virus infections drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in BK Virus infections
There are approx. 5+ key companies which are developing the therapies for BK Virus infections. The companies which have their BK Virus infections drug candidates in the most advanced stage, i.e. Phase III include, AlloVir.
  • Phases
DelveInsight’s report covers around 5+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
BK Virus infections pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

BK Virus infections: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses BK Virus infections therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging BK Virus infections drugs.

BK Virus infections Report Insights
  • BK Virus infections Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
BK Virus infections Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing BK Virus infections drugs?
  • How many BK Virus infections drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of BK Virus infections?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the BK Virus infections therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for BK Virus infections and their status?
  • What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
BK Virus infections: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
BK Virus infections – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  BK Virus infections companies’ collaborations, Licensing, Acquisition -Deal Value Trends
BK Virus infections Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
ALVR105 (Viralym-M): AlloVir
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Mid Stage Products (Phase II)
  Comparative Analysis
MAU868: Amplyx Pharmaceuticals
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Early stage products (Phase I)
  Comparative Analysis
SL V10: SL VAXiGEN
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Inactive Products
  Comparative Analysis
BK Virus infections Key Companies
BK Virus infections Key Products
BK Virus infections- Unmet Needs
BK Virus infections- Market Drivers and Barriers
BK Virus infections- Future Perspectives and Conclusion
BK Virus infections Analyst Views
BK Virus infections Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for BK Virus infections
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

LIST OF FIGURES

Figure 1 Total Products for BK Virus infections
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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