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Bacteremia - Pipeline Insight, 2021

May 2021 | 60 pages | ID: B41CE14C3C0EN
DelveInsight

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DelveInsight’s, “Bacteremia – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Bacteremia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Bacteremia Understanding

Bacteremia: Overview

Bacteremia refers to the presence of live bacteria in the blood. Bacteremia may result from ordinary activities (such as vigorous toothbrushing), dental or medical procedures, or from infections (such as pneumonia or a urinary tract infection). Usually, bacteremia that results from ordinary events, such as dental procedures, is temporary and causes no symptoms. Bacteremia that results from other conditions may cause fever. Bacteremia may occur during: Certain ordinary activities, Dental or medical procedures, certain bacterial infections, and Injection of recreational drugs. Identifying or presuming the source of infection will dictate the diagnostic measures taken. People who are at high risk of complications due to bacteremia (such as those who have an artificial heart valve or joint or certain heart valve abnormalities) are often given antibiotics. Bacteremia requires urgent and appropriate antibiotics. Delay in the administration of appropriate antibiotics is associated with increased morbidity and mortality.

'Bacteremia - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Bacteremia pipeline landscape is provided which includes the disease overview and Bacteremia treatment guidelines. The assessment part of the report embraces, in depth Bacteremia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Bacteremia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Bacteremia R&D. The therapies under development are focused on novel approaches to treat/improve Bacteremia.
Bacteremia Emerging Drugs Chapters

This segment of the Bacteremia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Bacteremia Emerging Drugs
  • Exebacase: ContraFect
Exebacase (CF-301) is a lysin with potent activity against Staphylococcus aureus ('Staph aureus'). Exebacase has the potential to be the first-in-class of a new treatment for patients with Staph aureus bacteremia. The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to exebacase (ContraFect) for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. The drug is currently in Phase III stage of development for the treatment of patients with Bacteremia.
  • N-Rephasin SAL200:Intron Biotechnology
N-Rephasin SAL200 (SAL200) has a unique mode of action and strong bactericidal activity independent of bacterial antibiotic susceptibility patterns. In addition, SAL200 is highly specific for staphylococci (i.e. target bacteria) and rarely lyses off non-target bacteria, including commensal bacteria, which may reduce clinical complications. The drug is currently being investigated in Phase II clinical trials.

Further product details are provided in the report

Bacteremia: Therapeutic Assessment

This segment of the report provides insights about the different Bacteremia drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Bacteremia
There are approx. 10+ key companies which are developing the therapies for Bacteremia. The companies which have their Bacteremia drug candidates in the most advanced stage, i.e. Phase III include, ContraFect.
  • Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Bacteremia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Bacteremia: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Bacteremia therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Bacteremia drugs.

Bacteremia Report Insights
  • Bacteremia Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Bacteremia Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Bacteremia drugs?
  • How many Bacteremia drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Bacteremia?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Bacteremia therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Bacteremia and their status?
  • What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
Bacteremia: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Bacteremia – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  Bacteremia companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Bacteremia Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
Exebacase: ContraFect
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Mid Stage Products (Phase II)
  Comparative Analysis
N-Rephasin SAL200: Intron Biotechnology
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Early Stage Products (Phase I)
  Comparative Analysis
ETX2514: Entasis Therapeutics
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Preclinical stage products
  Comparative Analysis
P 128 - GangaGen
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report
Inactive Products
  Comparative Analysis
Bacteremia Key Companies
Bacteremia Key Products
Bacteremia- Unmet Needs
Bacteremia- Market Drivers and Barriers
Bacteremia- Future Perspectives and Conclusion
Bacteremia Analyst Views
Bacteremia Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for Bacteremia
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

LIST OF FIGURES

Figure 1 Total Products for Bacteremia
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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