Antisense Oligonucleotide Therapeutics - Pipeline Insight, 2022
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DelveInsight’s, “Antisense Oligonucleotide Therapeutics - Pipeline Insight, 2022” report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Antisense Oligonucleotide Therapeutics pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Antisense Oligonucleotide Therapeutics: Overview
Antisense oligonucleotide (ASOs) are small-sized single-stranded nucleic acids that offer advantages over siRNAs in terms of targeting both nuclear and cytoplasmic located lncRNAs. Antisense oligonucleotide-based therapeutics involves downregulation of gene expression. Antisense oligonucleotides (AOs) are a class of synthetic nucleic acid molecules that are capable of regulating gene expression through binding to premature or mature messenger RNA (mRNA) targets. Antisense oligonucleotides (ASOs), known as genetic materials, are promising agents used in the regulation of unsuitable expression of genes in pathological situations by the specific inhibition of expression of their mRNA targets. By capitalizing “antisense” DNA approach, the overexpressed proteins can be blocked in several diseases such as cancer, neurological diseases, cardiovascular diseases, inflammation and autoimmune diseases, infectious diseases, etc. ASOs are emerging as a class of therapeutics with high potential to treat diseases affecting the CNS.
Report Highlights
This segment of the Antisense Oligonucleotide Therapeutics report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Antisense Oligonucleotide Therapeutics Emerging Drugs
Further product details are provided in the report……..
Antisense Oligonucleotide Therapeutics: Therapeutic Assessment
This segment of the report provides insights about the different Antisense Oligonucleotide Therapeutics drugs segregated based on following parameters that define the scope of the report, such as:
Antisense Oligonucleotide Therapeutics: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Antisense Oligonucleotide Therapeutics therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Antisense Oligonucleotide Therapeutics drugs.
Antisense Oligonucleotide Therapeutics Report Insights
Current Scenario and Emerging Therapies:
DelveInsight’s, “Antisense Oligonucleotide Therapeutics - Pipeline Insight, 2022” report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Antisense Oligonucleotide Therapeutics pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Antisense Oligonucleotide Therapeutics: Overview
Antisense oligonucleotide (ASOs) are small-sized single-stranded nucleic acids that offer advantages over siRNAs in terms of targeting both nuclear and cytoplasmic located lncRNAs. Antisense oligonucleotide-based therapeutics involves downregulation of gene expression. Antisense oligonucleotides (AOs) are a class of synthetic nucleic acid molecules that are capable of regulating gene expression through binding to premature or mature messenger RNA (mRNA) targets. Antisense oligonucleotides (ASOs), known as genetic materials, are promising agents used in the regulation of unsuitable expression of genes in pathological situations by the specific inhibition of expression of their mRNA targets. By capitalizing “antisense” DNA approach, the overexpressed proteins can be blocked in several diseases such as cancer, neurological diseases, cardiovascular diseases, inflammation and autoimmune diseases, infectious diseases, etc. ASOs are emerging as a class of therapeutics with high potential to treat diseases affecting the CNS.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Antisense Oligonucleotide Therapeutics R&D. The therapies under development are focused on novel approaches for Antisense Oligonucleotide Therapeutics.
This segment of the Antisense Oligonucleotide Therapeutics report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Antisense Oligonucleotide Therapeutics Emerging Drugs
- Cobitolimod: InDex Pharmaceuticals
- Prexigebersen: Bio-Path Holdings
Further product details are provided in the report……..
Antisense Oligonucleotide Therapeutics: Therapeutic Assessment
This segment of the report provides insights about the different Antisense Oligonucleotide Therapeutics drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players working on Antisense Oligonucleotide Therapeutics
- Phases
- Late-stage products (Phase III and
- Mid-stage products (Phase II and
- Early-stage products (Phase I/II and Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Infusion
- Intradermal
- Intramuscular
- Intranasal
- Intravaginal
- Oral
- Parenteral
- Subcutaneous
- Topical
- Molecule Type
- Vaccines
- Monoclonal Antibody
- Peptides
- Polymer
- Small molecule
- Product Type
Antisense Oligonucleotide Therapeutics: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Antisense Oligonucleotide Therapeutics therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Antisense Oligonucleotide Therapeutics drugs.
Antisense Oligonucleotide Therapeutics Report Insights
- Antisense Oligonucleotide Therapeutics Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Scenario and Emerging Therapies:
- How many companies are developing Antisense Oligonucleotide Therapeutics drugs?
- How many Antisense Oligonucleotide Therapeutics drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for Antisense Oligonucleotide Therapeutics?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Antisense Oligonucleotide Therapeutics therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Antisense Oligonucleotide Therapeutics and their status?
- What are the key designations that have been granted to the emerging drugs?
- InDex Pharmaceuticals
- Bio-Path Holdings
- Akcea Therapeutics
- Ionis Pharmaceuticals
- AstraZeneca
- Gene Signal
- Chamishi Therapeutics
- NeuBase Therapeutics
- Cobitolimod
- Prexigebersen
- Inotersen
- AKCEA APOCIII LRx
- ION 736
- NS-089/NCNP-02
- Aganirsen
- Research programme : antisense oligonucleotide therapeutics
- NT0100
Introduction
Executive Summary
Antisense Oligonucleotide Therapeutics: Overview
Structure
Mechanism of Action
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Antisense Oligonucleotide Therapeutics – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Antisense Oligonucleotide Therapeutics companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Antisense Oligonucleotide Therapeutics Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
Cobitolimod: InDex Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
Prexigebersen: Bio-Path Holdings
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
Comparative Analysis
ION 736: Ionis Pharmaceuticals/AstraZeneca
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
Comparative Analysis
NT0100: NeuBase Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Antisense Oligonucleotide Therapeutics Key Companies
Antisense Oligonucleotide Therapeutics Key Products
Antisense Oligonucleotide Therapeutics- Unmet Needs
Antisense Oligonucleotide Therapeutics- Market Drivers and Barriers
Antisense Oligonucleotide Therapeutics- Future Perspectives and Conclusion
Antisense Oligonucleotide Therapeutics Analyst Views
Antisense Oligonucleotide Therapeutics Key Companies
Appendix
Executive Summary
Antisense Oligonucleotide Therapeutics: Overview
Structure
Mechanism of Action
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Antisense Oligonucleotide Therapeutics – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Antisense Oligonucleotide Therapeutics companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Antisense Oligonucleotide Therapeutics Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
Cobitolimod: InDex Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
Prexigebersen: Bio-Path Holdings
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
Comparative Analysis
ION 736: Ionis Pharmaceuticals/AstraZeneca
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
Comparative Analysis
NT0100: NeuBase Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Antisense Oligonucleotide Therapeutics Key Companies
Antisense Oligonucleotide Therapeutics Key Products
Antisense Oligonucleotide Therapeutics- Unmet Needs
Antisense Oligonucleotide Therapeutics- Market Drivers and Barriers
Antisense Oligonucleotide Therapeutics- Future Perspectives and Conclusion
Antisense Oligonucleotide Therapeutics Analyst Views
Antisense Oligonucleotide Therapeutics Key Companies
Appendix
LIST OF TABLES
Table 1 Total Products for Antisense Oligonucleotide Therapeutics
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Table 1 Total Products for Antisense Oligonucleotide Therapeutics
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
LIST OF FIGURES
Figure 1 Total Products for Antisense Oligonucleotide Therapeutics
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Figure 1 Total Products for Antisense Oligonucleotide Therapeutics
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products