Amyloid precursor protein secretase inhibitors - Pipeline Insight, 2022
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DelveInsight’s, “Amyloid precursor protein secretase inhibitors - Pipeline Insight, 2022” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Amyloid precursor protein secretase inhibitors pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Amyloid precursor protein secretase inhibitors: Overview
According to the beta-amyloid (Abeta) hypothesis, compounds that inhibit gamma-secretase, the pivotal enzyme that generates Abeta, are potential therapeutics for Alzheimer's disease (AD). Studies in both transgenic and non-transgenic animal models of AD have indicated that gamma-secretase inhibitors, administered by the oral route, are able to lower brain Abeta concentrations. Inhibition of gamma-secretase presents a direct target for lowering A? production in the brain as a therapy for Alzheimer's disease (AD).
Report Highlights
This segment of the Amyloid precursor protein secretase inhibitors report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Amyloid precursor protein secretase inhibitors Emerging Drugs
It is currently in Phase III stage of development for the treatment of Desmoid tumors and is being developed by SpringWorks Therapeutics.
Further product details are provided in the report……..
Amyloid precursor protein secretase inhibitors: Therapeutic Assessment
This segment of the report provides insights about the different Amyloid precursor protein secretase inhibitors drugs segregated based on following parameters that define the scope of the report, such as:
Amyloid precursor protein secretase inhibitors: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Amyloid precursor protein secretase inhibitors therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Amyloid precursor protein secretase inhibitors drugs.
Amyloid precursor protein secretase inhibitors Report Insights
Current Scenario and Emerging Therapies:
DelveInsight’s, “Amyloid precursor protein secretase inhibitors - Pipeline Insight, 2022” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Amyloid precursor protein secretase inhibitors pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Amyloid precursor protein secretase inhibitors: Overview
According to the beta-amyloid (Abeta) hypothesis, compounds that inhibit gamma-secretase, the pivotal enzyme that generates Abeta, are potential therapeutics for Alzheimer's disease (AD). Studies in both transgenic and non-transgenic animal models of AD have indicated that gamma-secretase inhibitors, administered by the oral route, are able to lower brain Abeta concentrations. Inhibition of gamma-secretase presents a direct target for lowering A? production in the brain as a therapy for Alzheimer's disease (AD).
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Amyloid precursor protein secretase inhibitors R&D. The therapies under development are focused on novel approaches for Amyloid precursor protein secretase inhibitors.
This segment of the Amyloid precursor protein secretase inhibitors report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Amyloid precursor protein secretase inhibitors Emerging Drugs
- Nirogacestat: SpringWorks Therapeutics
It is currently in Phase III stage of development for the treatment of Desmoid tumors and is being developed by SpringWorks Therapeutics.
- AL 101: Ayala Pharmaceuticals
Further product details are provided in the report……..
Amyloid precursor protein secretase inhibitors: Therapeutic Assessment
This segment of the report provides insights about the different Amyloid precursor protein secretase inhibitors drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players working on Amyloid precursor protein secretase inhibitors
- Phases
- Late-stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage products (Phase I/II and Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Infusion
- Intradermal
- Intramuscular
- Intranasal
- Intravaginal
- Oral
- Parenteral
- Subcutaneous
- Topical
- Molecule Type
- Vaccines
- Monoclonal Antibody
- Peptides
- Polymer
- Small molecule
- Product Type
Amyloid precursor protein secretase inhibitors: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Amyloid precursor protein secretase inhibitors therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Amyloid precursor protein secretase inhibitors drugs.
Amyloid precursor protein secretase inhibitors Report Insights
- Amyloid precursor protein secretase inhibitors Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Scenario and Emerging Therapies:
- How many companies are developing Amyloid precursor protein secretase inhibitors drugs?
- How many Amyloid precursor protein secretase inhibitors drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for Amyloid precursor protein secretase inhibitors?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Amyloid precursor protein secretase inhibitors therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Amyloid precursor protein secretase inhibitors and their status?
- What are the key designations that have been granted to the emerging drugs?
- Ayala Pharmaceuticals
- SpringWorks Therapeutics
- Pipeline Therapeutics
- AL102
- AL 101
- Nirogacestat
- PIPE-505
Introduction
Executive Summary
Amyloid precursor protein secretase inhibitors: Overview
Structure
Mechanism of Action
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
Comparative Analysis
Nirogacestat: SpringWorks Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
AL 101: Ayala Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
Drug Name: Company Name
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
Comparative Analysis
Drug Name: Company Name
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Amyloid precursor protein secretase inhibitors Key Companies
Amyloid precursor protein secretase inhibitors Key Products
Amyloid precursor protein secretase inhibitors- Unmet Needs
Amyloid precursor protein secretase inhibitors- Market Drivers and Barriers
Amyloid precursor protein secretase inhibitors- Future Perspectives and Conclusion
Amyloid precursor protein secretase inhibitors Analyst Views
Amyloid precursor protein secretase inhibitors Key Companies
Appendix
Executive Summary
Amyloid precursor protein secretase inhibitors: Overview
Structure
Mechanism of Action
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
Late Stage Products (Phase III)
Comparative Analysis
Nirogacestat: SpringWorks Therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
AL 101: Ayala Pharmaceuticals
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
Comparative Analysis
Drug Name: Company Name
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
Comparative Analysis
Drug Name: Company Name
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
Amyloid precursor protein secretase inhibitors Key Companies
Amyloid precursor protein secretase inhibitors Key Products
Amyloid precursor protein secretase inhibitors- Unmet Needs
Amyloid precursor protein secretase inhibitors- Market Drivers and Barriers
Amyloid precursor protein secretase inhibitors- Future Perspectives and Conclusion
Amyloid precursor protein secretase inhibitors Analyst Views
Amyloid precursor protein secretase inhibitors Key Companies
Appendix