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Allergic rhinitis - Pipeline Insight, 2021

June 2021 | 90 pages | ID: A4FE183BD19BEN
DelveInsight

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DelveInsight’s, “Allergic rhinitis - Pipeline Insight, 2021,” report provides comprehensive insights about 35+ companies and 35+ pipeline drugs in Allergic rhinitis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Allergic rhinitis Understanding

Allergic rhinitis: Overview

Allergic rhinitis, or hay fever, is an allergic response to specific allergens. Common symptoms of allergic rhinitis include sneezing, runny nose, coughing, sore or scratchy throat, itchy eyes, watery eyes, dark circles under the eyes, frequent headaches, eczema-type symptoms, hives, and excessive fatigue. Allergic rhinitis is usually a long-standing condition that often goes undetected in the primary-care setting. A thorough history, physical examination and allergen skin testing are important for establishing the diagnosis of allergic rhinitis. Treatment of allergic rhinitis is symptomatic and depends on the type of allergen. Management incudes medication like intranasal corticosteroids, antihistamines, decongestants, immunotherapy, eye drops and nasal sprays. Second-generation oral antihistamines and intranasal corticosteroids are the mainstay of treatment.

'Allergic rhinitis - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Allergic rhinitis pipeline landscape is provided which includes the disease overview and Allergic rhinitis treatment guidelines. The assessment part of the report embraces, in depth Allergic rhinitis commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Allergic rhinitis collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Allergic rhinitis R&D. The therapies under development are focused on novel approaches to treat/improve Allergic rhinitis.
Allergic rhinitis Emerging Drugs Chapters

This segment of the Allergic rhinitis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Allergic rhinitis Emerging Drugs
  • REGN5713-5714-5715: Regeneron Pharmaceuticals
REGN5713-5714-5715 is a cocktail of three Bet v1 monoclonal antibodies. Regeneron Pharmaceuticals is investigating REGN5713-5714-5715 as intravenous injections in Phase III clinical studies for the treatment of allergic rhinitis and conjunctivitis.
  • Injectable MPL allergy vaccine: Allergy Therapeutics
Injectable MPL allergy vaccine is a subcutaneously administered vaccine containing glutaraldehyde-modified allergens and the adjuvants 3-deacylated monophosphoryl lipid A (MPL) and L-tyrosine. The drug is in Phase II/III clinical developmental studies for the treatment of Seasonal allergic rhinitis.

Further product details are provided in the report..

Allergic rhinitis: Therapeutic Assessment

This segment of the report provides insights about the different Allergic rhinitis drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Allergic rhinitis
There are approx. 35+ key companies which are developing the therapies for Allergic rhinitis. The companies which have their Allergic rhinitis drug candidates in the most advanced stage, i.e. Phase III include, Regeneron Pharmaceuticals.
  • Phases
DelveInsight’s report covers around 35+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Allergic rhinitis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravitreal
  • Subretinal
  • Topical
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Allergic rhinitis: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Allergic rhinitis therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Allergic rhinitis drugs.

Allergic rhinitis Report Insights
  • Allergic rhinitis Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Allergic rhinitis Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Allergic rhinitis drugs?
  • How many Allergic rhinitis drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Allergic rhinitis?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Allergic rhinitis therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Allergic rhinitis and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • Abdi Ibrahim Pharmaceuticals
  • Allergy Therapeutics
  • Regeneron Pharmaceuticals
  • Laboratorios LETI
  • ALK-Abello
  • Advagene Biopharma
  • CSPC ZhongQi Pharmaceutical Technology
  • Array BioPharma
  • Immunotek
Key Products
  • AI-201901
  • Injectable MPL allergy vaccine
  • REGN5713-5714-5715
  • House dust mite allergy immunotherapy
  • Birch pollen allergy vaccine tablet
  • B 244
  • AD 17002
  • CSPCHA-115
  • VTX-1463
  • MM09-MG01
  • MG 01/T 517
Introduction
Executive Summary
Allergic rhinitis: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Allergic rhinitis – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  Allergic rhinitis companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Allergic rhinitis Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
REGN5713-5714-5715: Regeneron Pharmaceuticals
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Mid Stage Products (Phase II/III)
  Comparative Analysis
Injectable MPL allergy vaccine: Allergy Therapeutics
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Early Stage Products (Phase I/II)
  Comparative Analysis
B 244: AOBiome
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Preclinical/Discovery Stage Products
  Comparative Analysis
MM09-MG01: Immunotek
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Inactive Products
  Comparative Analysis
Allergic rhinitis Key Companies
Allergic rhinitis Key Products
Allergic rhinitis- Unmet Needs
Allergic rhinitis- Market Drivers and Barriers
Allergic rhinitis- Future Perspectives and Conclusion
Allergic rhinitis Analyst Views
Allergic rhinitis Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for Allergic rhinitis
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

LIST OF FIGURES

Figure 1 Total Products for Allergic rhinitis
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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