ADC Contract Manufacturing Market (5th Edition) by Phase of Development (Phase I, Phase II and Phase III), Scale of Operation (Clinical and Commercial), Type of Component Manufacturing (Antibody Manufacturing, HPAPI / Cytotoxic Payload, Linker and Conjugation Manufacturing, and Fill / Finish), Target Indications (Solid Tumors, Hematological Malignancies and Others), Type of Payload (Maytansinoid, Auristatin, Camptothecin, PBD and Others), Type of Linker (SMCC, VC, Malemide, Peptide Linker and Others), Type of Antibody Origin (Humanized, Chimeric, Murine, Human and Others), Antibody Isotype (IgG1and Others) and Geography (North America, Europe, Asia-Pacific and Rest of the World), 2022-2035
The ADC contract manufacturing market is expected to reach USD 2.8 billion by 2022 anticipated to grow at a CAGR of 11.8% during the forecast period 2022-2035.
Over the past two decades, antibody therapeutics have emerged as a crucial component in the treatment of diverse diseases, particularly cancer, within the pharmaceutical industry. This sector has experienced rapid expansion, marked by substantial technological advancements. Researchers are actively exploring the potential of antibody drug conjugates (ADCs) in addressing a wide spectrum of conditions. ADCs offer distinct advantages compared to standard antibody treatments, including enhanced efficacy, greater stability, reduced toxicity, improved tumor targeting, increased drug tolerance, and minimized systemic exposure. Notably, the FDA has approved more than 10 ADCs in recent years, with over 700 clinical trials underway for various disorders. Investments totaling USD 14.8 billion since 2014 underscore the escalating interest and therapeutic potential of these precisely targeted medications. However, the production of these therapeutics presents challenges. These encompass the generation of antibody aggregates, management of drug/linker side reactions, handling of highly toxic compounds, and ensuring consistency in drug-antibody ratios across production batches. Furthermore, the manufacturing process often relies on costly linker technologies. To address these challenges, approximately 70-80% of ADC contract manufacturing is outsourced to specialized organizations possessing requisite expertise. The landscape of ADC contract manufacturing encompasses a blend of start-ups, mid-sized firms, and established players. More than a third of these entities operate across multiple geographical locations, offering diverse services at varying scales.
In response to the escalating demands of ADC developers, Contract Manufacturing Organizations (CMOs) engaged in ADC contract manufacturing are broadening their capacities to evolve into comprehensive service providers. With the anticipated surge in demand for ADCs, the associated contract manufacturing market is poised for substantial growth in the projected period.
Report Coverage
Over the past two decades, antibody therapeutics have emerged as a crucial component in the treatment of diverse diseases, particularly cancer, within the pharmaceutical industry. This sector has experienced rapid expansion, marked by substantial technological advancements. Researchers are actively exploring the potential of antibody drug conjugates (ADCs) in addressing a wide spectrum of conditions. ADCs offer distinct advantages compared to standard antibody treatments, including enhanced efficacy, greater stability, reduced toxicity, improved tumor targeting, increased drug tolerance, and minimized systemic exposure. Notably, the FDA has approved more than 10 ADCs in recent years, with over 700 clinical trials underway for various disorders. Investments totaling USD 14.8 billion since 2014 underscore the escalating interest and therapeutic potential of these precisely targeted medications. However, the production of these therapeutics presents challenges. These encompass the generation of antibody aggregates, management of drug/linker side reactions, handling of highly toxic compounds, and ensuring consistency in drug-antibody ratios across production batches. Furthermore, the manufacturing process often relies on costly linker technologies. To address these challenges, approximately 70-80% of ADC contract manufacturing is outsourced to specialized organizations possessing requisite expertise. The landscape of ADC contract manufacturing encompasses a blend of start-ups, mid-sized firms, and established players. More than a third of these entities operate across multiple geographical locations, offering diverse services at varying scales.
In response to the escalating demands of ADC developers, Contract Manufacturing Organizations (CMOs) engaged in ADC contract manufacturing are broadening their capacities to evolve into comprehensive service providers. With the anticipated surge in demand for ADCs, the associated contract manufacturing market is poised for substantial growth in the projected period.
Report Coverage
- Analyze the ADC (Antibody-Drug Conjugate) contract manufacturing market by considering phases of development, operational scale, component manufacturing types, targeted indications, payload types, linker types, antibody origin, antibody isotype, and geographical factors.
- Evaluate factors such as drivers, restraints, opportunities, and challenges that impact market growth.
- Assess potential advantages and obstacles within the market, providing insights into the competitive landscape for leading players.
- Forecast revenue for market segments across four major regions.
- Conduct a comprehensive market analysis of contract manufacturing entities in the ADC sector. Evaluate criteria including company size, establishment year, headquarters location, offered services (antibody manufacturing, HPAPI/payload synthesis, linker manufacturing, conjugation, and fill-finish), additional ADC services, operational scale (preclinical, clinical, commercial), and manufacturing facility locations.
- Perform a competitive analysis of ADC manufacturers, focusing on strengths in manufacturing, services, and supplier aspects. Assess based on operational scale, service offerings, service diversity, facility locations, employee count, and industry experience.
- Develop detailed profiles of selected ADC manufacturers based on competitiveness analysis, encompassing company overview, financial information, ADC manufacturing capabilities, facility locations, recent developments, and future outlook.
- Analyze expansion initiatives of ADC contract manufacturing service providers between 2012-2022, evaluating expansion types, services offered, facility locations, operational scales, and active market players.
- Investigate recent partnerships among ADC contract manufacturing entities, detailing partnership models (e.g., manufacturing agreements, acquisitions, licensing) and their nature, providing insights into collaborations between stakeholders.
- Provide a qualitative analysis for ADC developers deciding between in-house manufacturing and outsourcing, highlighting factors influencing this decision-making process.
- Outline the steps involved in ADC manufacturing (antibody, payload, linker, conjugation, fill-finish), including associated cost requirements for each stage.
- Estimate global ADC manufacturing capacity across companies by size, geographical regions, and major players in bioconjugation.
- Offer an overview of approved and under-development ADCs, including development phases, indications, antigens, antibody origins, isotypes, payload types, and linkers.
- Review the evolution of ADC conjugation technologies, focusing on past approaches, linker generations, and competition between technology platforms.
- Analyze completed, ongoing, and planned clinical studies, considering parameters such as trial phase, status, indications, sponsors, and enrolled patients.
- Estimate annual ADC product demand (in kilograms) considering commercial and clinical scale requirements based on patient population, dosing frequency, and approved and clinical stage candidates.
- Analyze over 80 ADC-based therapy developers for potential partnerships with contract service providers, considering company size, experience, pipeline strength, and manufacturing capabilities.
- Develop a regional capability assessment comparing key geographies based on ADC manufacturers, facilities, expansions, installed capacity, clinical trials, and regional demand.
- Present a proprietary 2x2 representation depicting the current ADC market scenario, considering existing competition and growth opportunities across emerging and established market segments.
- Discuss market trends, drivers, challenges, and opportunities using a SWOT framework with a Harvey ball analysis to highlight their relative impacts on the ADC contract manufacturing market.
- MabPlex
- AbbVie Contract Manufacturing
- Lonza
- Catalent Pharma Solutions
- Goodwin Biotechnology
- Piramal Pharma Solutions
- Millipore Sigma
- Abzena
- CARBOGEN AMCIS
- WuXi Biologics
- Cerbios-Pharma
- Formosa Laboratories
- Creative Biolabs
- Novasep
- Sterling Pharma Solutions
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4 Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Key Components of Antibody Drug Conjugates (ADCs)
3.2.1. Antibody
3.2.2. Cytotoxin
3.2.3. Linker
3.3. ADC Manufacturing
3.3.1. Key Steps
3.3.2. Technical Challenges
3.3.3. Need for Outsourcing
3.4. Challenges Associated with Supply Chain and Method Transfer
3.4.1. Growing Demand for One-Stop-Shops and Integrated Service Providers
3.5. Key Considerations While Selecting a CMO Partner
3.6. Future Perspective
4. ADC CONTRACT MANUFACTURING SERVICE PROVIDERS: MARKET LANDSCAPE
4.1. Chapter Overview
4.2. ADC Contract Manufacturing Service Providers: Overall Market Landscape
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis By Company Size
4.2.3. Analysis by Location of Headquarters
4.2.4. Analysis by Service(s) Offered
4.2.5. Analysis by Other ADC Service(s) Offered
4.2.6. Analysis by Scale of Operation
4.2.7. Analysis by Location of Dedicated Manufacturing Facility
4.3. List of Antibody Contract Manufacturing Service Providers
4.4. List of HPAPI / Cytotoxic Payload Contract Manufacturing Service Providers
4.5. List of Biologics Fill / Finish Service Providers
5. COMPANY PROFILES
5.1. Chapter Overview
5.2. MabPlex
5.2.1. Company Overview
5.2.2. ADC Offerings
5.2.3. Manufacturing Facilities
5.2.4. Recent Development and Future Outlook
5.3. AbbVie Contract Manufacturing
5.3.1. Company Overview
5.3.2. ADC Offerings
5.3.3. Manufacturing Facilities
5.3.4. Recent Development and Future Outlook
5.4. Lonza
5.4.1. Company Overview
5.4.2. Financial Information
5.4.3. ADC Offerings
5.4.4. Manufacturing Facilities
5.4.5. Recent Development and Future Outlook
5.5. Catalent Pharma Solutions
5.5.1. Company Overview
5.5.2. Financial Information
5.5.3. ADC Offerings
5.5.4. Manufacturing Facilities
5.5.5. Recent Development and Future Outlook
5.6. Goodwin Biotechnology
5.6.1. Company Overview
5.6.2. ADC Offerings
5.6.3. Manufacturing Facilities
5.6.4. Recent Development and Future Outlook
5.7. Piramal Pharma Solutions
5.7.1. Company Overview
5.7.2. ADC Offerings
5.7.3. Manufacturing Facilities
5.7.4. Recent Development and Future Outlook
5.8. Millipore Sigma
5.8.1. Company Overview
5.8.2. ADC Offerings
5.8.3. Manufacturing Facilities
5.8.4. Recent Development and Future Outlook
5.9. Abzena
5.9.1. Company Overview
5.9.2. ADC Offerings
5.9.3. Manufacturing Facilities
5.9.4. Recent Development and Future Outlook
5.10. CARBOGEN AMCIS
5.10.1. Company Overview
5.10.2. ADC Offerings
5.10.3. Manufacturing Facilities
5.10.4. Recent Development and Future Outlook
5.11. WuXi Biologics
5.11.1. Company Overview
5.11.2. Financial Information
5.11.3. ADC Offerings
5.11.4. Manufacturing Facilities
5.11.5. Recent Development and Future Outlook
5.12. Cerbios-Pharma
5.12.1. Company Overview
5.12.2. ADC Offerings
5.12.3. Manufacturing Facilities
5.12.4. Recent Development and Future Outlook
5.13. Formosa Laboratories
5.13.1. Company Overview
5.13.2. ADC Offerings
5.13.3. Manufacturing Facilities
5.13.4. Recent Development and Future Outlook
5.14. Creative Biolabs
5.14.1. Company Overview
5.14.2. ADC Offerings
5.14.3. Manufacturing Facilities
5.14.4. Recent Development and Future Outlook
5.15. Novasep
5.15.1. Company Overview
5.15.2. ADC Offerings
5.15.3. Manufacturing Facilities
5.15.4. Recent Development and Future Outlook
5.16. Sterling Pharma Solutions
5.16.1. Company Overview
5.16.2. ADC Offerings
5.16.3. Manufacturing Facilities
5.16.4. Recent Development and Future Outlook
6. COMPANY COMPETITIVENESS ANALYSIS
6.1. Chapter Overview
6.2. Methodology and Key Parameters
6.3. ADC Contract Manufacturing Service Providers: Company Competitiveness Analysis
6.3.1. ADC Contract Manufacturing Service Providers based in North America
6.3.2. ADC Contract Manufacturing Service Providers based in Europe
6.3.3. ADC Contract Manufacturing Service Providers based in Asia-Pacific
7. ADC CONTRACT MANUFACTURING SERVICE PROVIDERS: RECENT EXPANSIONS
7.1. Chapter Overview
7.2. ADC Contract Manufacturing Service Providers: Recent Expansions
7.2.1. Analysis by Year of Expansion
7.2.2. Analysis by Type of Expansion
7.2.3. Analysis by Type of Service(s) Offered
7.2.4. Analysis by Location of Expanded Facility
7.2.5. Analysis by Scale of Operation
7.2.6. Most Active Players: Analysis by Number of Expansions
8. ADC CONTRACT MANUFACTURING SERVICE PROVIDERS: PARTNERSHIPS AND COLLABORATIONS
8.1. Chapter Overview
8.2. Partnership Models
8.3. ADC Contract Manufacturing Service Providers: List of Partnerships and Collaborations
8.3.1. Analysis by Year of Partnership
8.3.2. Analysis by Type of Partnership
8.3.3. Analysis by Type of Service(s) Provided
8.3.4. Analysis by Scale of Operation
8.3.5. Most Active Players: Analysis by Number of Partnerships
8.3.6. Regional Analysis
8.3.6.1. Local and International Agreements
8.3.6.2. Intercontinental and Intracontinental Agreements
9. MAKE VERSUS BUY DECISION MAKING
9.1. Chapter Overview
9.2. Assumptions and Key Parameters
9.2.1. Scenario
9.2.2. Scenario
9.2.3. Scenario
9.2.4. Scenario
9.3. Concluding Remarks
10. VALUE CHAIN ANALYSIS
10.1. Chapter Overview
10.2. ADC Development Value Chain
10.3. Cost Distribution Across the Value Chain
10.3.1. Cost Associated with Antibody Manufacturing
10.3.2. Cost Associated with Payload and Linker Manufacturing
10.3.3. Cost Associated with Conjugation
10.3.4. Cost Associated with Fill / Finish
11. ADC MANUFACTURING: CAPACITY ANALYSIS
11.1. Chapter Overview
11.2. Key Assumptions and Methodology
11.3. ADC Manufacturing: Global Installed Capacity
11.3.1. Analysis by Company Size
11.3.2. Analysis by Location of Headquarters
11.3.3. Analysis by Location of Manufacturing Facilities
11.3.3.1 Analysis by Country
11.3.3.2. Analysis by Continent
11.3.4. Analysis by Key Players
12. ADC THERAPEUTICS: MARKET OVERVIEW
12.1. Chapter Overview
12.2. List of ADC Therapeutics
12.2.1. Analysis by Phase of Development
12.2.2. Analysis by Target Disease Indication
12.2.3. Analysis by Target Antigen
12.2.4. Analysis by Antibody Isotype
12.2.5. Analysis by Type of Linker
12.2.6. Analysis by Payload / Warhead
12.2.7. Analysis by Type of Payload
12.3. Antibody Drug Conjugates: List of Therapy Developers
12.3.1. Analysis by Company Size and Location of Headquarters
12.3.2. List of Discontinued Drugs
13. NOVEL ADC CONJUGATION TECHNOLOGY PLATFORMS
13.1. Chapter Overview
13.2. First Generation ADC Technologies
13.3. Second Generation ADC Technologies
13.3.1. Cysteine and Selenocysteine Engineering
13.3.2. Unnatural Amino Acid Engineering
13.3.3. Amino-Terminal Serine Engineering
13.4. Third Generation ADC Technologies
13.4.1. Enzyme-Assisted Ligation Approaches
13.4.2. Glycan Remodeling Approaches
13.4.3. Ligation at Fab Nucleotide-Binding Site
13.4.4. Cysteine Rebridging
13.4.5. Avoiding or Limiting Retro-Michael Drug Deconjugation
13.5. Other Emerging ADC Technologies
13.6. Evolutionary Analysis
14. CLINICAL TRIALS ANALYSIS
14.1. Chapter Overview
14.2. Scope and Methodology
14.3. ADC Therapeutics: Clinical Trial Analysis
14.3.1. Analysis by Trial Registration Year
14.3.2. Analysis by Trial Phase
14.3.3. Analysis by Trial Status
14.3.4. Analysis by Type of Payload
14.3.5. Analysis by Type of Linker
14.3.6. Analysis by Antibody Isotope
14.3.7. Most Active Players: Analysis by Number of Clinical Trials
14.3.8. Most Active Sponsors: Analysis by Number of Clinical Trials
14.3.9. Analysis by Number of Trials and Geography
14.3.10. Analysis by Number of Trials, Trial Status and Geography
14.3.11. Analysis by Enrolled Patient Population, Trial Status and Geography
14.4. ADC Therapeutics: Analysis by Antibody Isotope and Geography
14.4.1. IgG based Molecules
14.4.1.1. Analysis by Phase of Development and Geography
14.4.1.2. Analysis by Trial Status and Geography
14.4.1.3. Analysis by Enrolled Patient Population and Geography
14.4.2. IgG1 based Molecules
14.4.2.1. Analysis by Phase of Development and Geography
14.4.2.2. Analysis by Trial Status and Geography
14.4.2.3. Analysis by Enrolled Patient Population and Geography
14.4.3. IgG4 based Molecules
14.4.3.1. Analysis by Phase of Development and Geography
14.4.3.2. Analysis by Trial Status and Geography
14.4.3.3. Analysis by Enrolled Patient Population and Geography
14.4.4. Other Antibody Isotope based Molecules
14.4.4.1. Analysis by Phase of Development and Geography
14.4.4.2. Analysis by Trial Status and Geography
14.4.4.3. Analysis by Enrolled Patient Population and Geography
14.5. ADC Therapeutics: Analysis by Type of Payload and Geography
14.5.1. Auristatin based Molecules
14.5.1.1. Analysis by Phase of Development and Geography
14.5.1.2. Analysis by Trial Status and Geography
14.5.1.3. Analysis by Enrolled Patient Population and Geography
14.5.2. Calicheamicin (Ozogamicin) based Molecules
14.5.2.1. Analysis by Phase of Development and Geography
14.5.2.2. Analysis by Trial Status and Geography
14.5.2.3. Analysis by Enrolled Patient Population and Geography
14.5.3. Maytansine based Molecules
14.5.3.1. Analysis by Phase of Development and Geography
14.5.3.2. Analysis by Geography and Trial Status and Geography
14.5.3.3. Analysis by Enrolled Patient Population and Geography
14.5.4. Exatecan based Molecules
14.5.4.1. Analysis by Phase of Development and Geography
14.5.4.2. Analysis by Trial Status and Geography
14.5.4.3. Analysis by Enrolled Patient Population and Geography
14.5.5. Maytansinoid based Molecules
14.5.5.1. Analysis by Phase of Development and Geography
14.5.5.2. Analysis by Geography and Trial Status
14.5.5.3. Analysis by Geography and Enrolled Patient Population
14.5.2. Camptothecin based Molecules
14.5.6.1. Analysis by Phase of Development and Geography
14.5.6.2. Analysis by Trial Status and Geography
14.5.6.3. Analysis by Enrolled Patient Population and Geography
14.5.2. Other Payload based Molecules
14.5.7.1. Analysis by Phase of Development and Geography
14.5.7.2. Analysis by Trial Status and Geography
14.5.7.3. Analysis by Enrolled Patient Population and Geography
14.6. ADC Therapeutics: Analysis by Type of Linker and Geography
14.6.1. VC based Molecules
14.6.1.1. Analysis by Phase of Development and Geography
14.6.1.2. Analysis by Trial Status and Geography
14.6.1.3. Analysis by Enrolled Patient Population and Geography
14.6.2. Peptide Linker based Molecules
14.6.2.1. Analysis by Phase of Development and Geography
14.6.2.2. Analysis by Trial Status and Geography
14.6.2.3. Analysis by Enrolled Patient Population and Geography
14.6.3. Mc-Val-Cit-PABC based Molecules
14.6.3.1. Analysis by Phase of Development and Geography
14.6.3.2. Analysis by Trial Status and Geography
14.6.3.3. Analysis by Enrolled Patient Population and Geography
14.6.4. AcBut based Molecules
14.6.4.1. Analysis by Phase of Development and Geography
14.6.4.2. Analysis by Trial Status and Geography
14.6.4.3. Analysis by Enrolled Patient Population and Geography
14.6.5. SMCC based Molecules
14.6.5.1. Analysis by Phase of Development and Geography
14.6.5.2. Analysis by Trial Status and Geography
14.6.5.3. Analysis by Enrolled Patient Population and Geography
14.6.6. SPDB based Molecules
14.6.6.1. Analysis by Phase of Development and Geography
14.6.6.2. Analysis by Trial Status and Geography
14.6.6.3. Analysis by Enrolled Patient Population and Geography
14.6.7. Others Linker based Molecules
14.6.7.1. Analysis by Phase of Development and Geography
14.6.7.2. Analysis by Trial Status and Geography
14.6.7.3. Analysis by Enrolled Patient Population and Geography
15. LIKELY PARTNER ANALYSIS
15.1. Chapter Overview
15.2. Scope and Methodology
15.3. Key Potential Strategic Partners for ADC Therapeutics Developers
15.3.1. Likely Partner Opportunities in North America
15.3.2. Likely Partner Opportunities in Europe
15.3.3. Likely Partner Opportunities in Asia-Pacific
16. ADC THERAPEUTICS: DEMAND ANALYSIS
16.1. Chapter Overview
16.2. Key Assumptions and Methodology
16.3. ADC Therapeutics: Overall Annual Demand
16.3.1. ADC Therapeutics: Annual Commercial Demand
16.3.1.1. Analysis by Type of Cancer
16.3.1.2. Analysis by Antibody Origin
16.3.1.3. Analysis by Antibody Isotype
16.3.1.4. Analysis by Type of Payload
16.3.1.5. Analysis by Type of Linker
16.3.1.6 Analysis by Key Geographical Regions
16.3.2. ADC Therapeutics: Annual Clinical Demand
16.3.2.1. Analysis by Phase of Development
16.3.2.2. Analysis by Type of Cancer
16.3.2.3. Analysis by Antibody Origin
16.3.2.4. Analysis by Antibody Isotype
16.3.2.5. Analysis by Type of Payload
16.3.2.6. Analysis by Type of Linker
16.3.2.7. Analysis by Key Geographical Regions
16.4. ADC Therapeutics: Demand and Supply Analysis
17. REGIONAL CAPABILITY ASSESSMENT ANALYSIS
17.1. Chapter Overview
17.2. Assumptions and Key Parameters
17.3. Regional Capability Assessment in North America
17.4. Regional Capability Assessment in Europe
17.5. Regional Capability Assessment in Asia-Pacific
17.6. Concluding Remarks
18. ATTRACTIVENESS COMPETETIVENESS MATRIX
18.1. Chapter Overview
18.2. AC Matrix: An Overview
18.2.1. Strong Business Segments
18.2.2. Average Business Segments
18.2.3. Weak Business Segments
18.3. AC Matrix: Analytical Methodology
18.4. AC Matrix: Overall ADC Contract Manufacturing Market Scenario
18.4.1. AC Matrix: ADC Contract Manufacturing Scenario for Type of Service(s) Offered
18.4.2. AC Matrix: ADC Contract Manufacturing Scenario for Key Geographies
19. MARKET SIZING AND OPPORTUNITY ANALYSIS
19.1. Chapter Overview
19.2. Input Data and Key Assumptions
19.3. Forecast Methodology
19.4. Global ADC Therapeutics Market, 2022-2035
19.5. Global ADC Contract Manufacturing Market, 2022-2035
19.5.1. ADC Contract Manufacturing Market: Analysis by Type of Component Manufacturing, 2022-2035
19.5.2. ADC Contract Manufacturing Market: Analysis by Phase of Development, 2022-2035
19.6. ADC Contract Manufacturing Market for Commercial Products, 2022-2035
19.6.1. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Component Manufacturing, 2022-2035
19.6.1.1. ADC Contract Manufacturing Market for Commercial Products, Analysis by Antibody Origin, 2022-2035
19.6.1.2. ADC Contract Manufacturing Market for Commercial Products, Analysis by Antibody Isotype, 2022-2035
19.6.1.3. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Payload, 2022-2035
19.6.1.4. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Linker, 2022-2035
19.6.2. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Cancer, 2022-2035
19.6.3. ADC Contract Manufacturing Market for Commercial Products, Analysis by Key Geographical Regions, 2022-2035
19.6.3.1. ADC Contract Manufacturing Market for Commercial Products in North America, 2022-2035
19.6.3.2. ADC Contract Manufacturing Market for Commercial Products in EU5, 2022-2035
19.6.3.3. ADC Contract Manufacturing Market for Commercial Products in Rest of the World, 2022-2035
19.7. ADC Contract Manufacturing Market for Clinical Products, 2022-2035
19.7.1. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Component Manufacturing, 2022-2035
19.7.1.1. ADC Contract Manufacturing Market for Clinical Products, Analysis by Antibody Origin, 2022-2035
19.7.1.2. ADC Contract Manufacturing Market for Clinical Products, Analysis by Antibody Isotype, 2022-2035
19.7.1.3. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Payload, 2022-2035
19.7.1.4. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Linker, 2022-2035
19.7.2. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Cancer, 2022-2035
19.7.3. ADC Contract Manufacturing Market for Clinical Products, Analysis by Key Geographical Regions, 2022-2035
19.7.3.1. ADC Contract Manufacturing Market for Clinical Products in North America, 2022-2035
19.7.3.2. ADC Contract Manufacturing Market for Clinical Products in Europe, 2022-2035
19.7.3.3. ADC Contract Manufacturing Market for Clinical Products in Asia-Pacific, 2022-2035
19.7.3.4. ADC Contract Manufacturing Market for Clinical Products in MENA, 2022-2035
19.7.3.5. ADC Contract Manufacturing Market for Clinical Products in Latin America, 2022-2035
19.7.3.6. ADC Contract Manufacturing Market for Clinical Products in Rest of the World, 2022-2035
20. SWOT ANALYSIS
20.1. Chapter Overview
20.2. Strengths
20.3. Weaknesses
20.4. Opportunities
20.5. Threats
20.6. Comparison of SWOT Factors
21. CONCLUDING REMARKS
22. INTERVIEW TRANSCRIPTS
22.1. Chapter Overview
22.2. BSP Pharmaceuticals
22.2.1. Company Snapshot
22.2.2. Interview Transcript: Aldo Braca (Chief Executive Officer and Giorgio Salciarini, Technical Business Development Manager)
22.3. Oxford BioTherapeutics
22.3.1. Company Snapshot
22.3.2. Interview Transcript: Christian Rohlff (Chief Executive Officer & Founder)
22.4. Abzena
22.4.1. Company Snapshot
22.4.2. Interview Transcript: ex-John Burt (Chief Executive Officer)
22.5. Syndivia
22.5.1. Company Snapshot
22.5.2. Interview Transcript: Sasha Koniev (Chief Executive Officer & Co-Founder)
22.6. Cerbios-Pharma
22.6.1. Company Snapshot
22.6.2. Interview Transcript: Denis Angioletti (Chief Commercial Officer)
22.7. NBE-Therapeutics
22.7.1. Company Snapshot
22.7.2. Interview Transcript: Wouter Verhoeven (Chief Business Officer)
22.8. Eisai
22.8.1. Company Snapshot
22.8.2. Interview Transcript: Toshimitsu Uenaka (Executive Director and Takashi Owa, Chief Innovation Officer)
22.9. Synaffix
22.9.1. Company Snapshot
22.9.2. Interview Transcript: Anthony DeBoer (Director, Business Development)
22.10. Pierre Fabre
22.10.1. Company Snapshot
22.10.2. Interview Transcript: ex-Christian Bailly (Director of CDMO)
22.11. Goodwin Biotechnology
22.11.1. Company Snapshot
22.11.2. Interview Transcript: David Cunningham (Director Corporate Development)
22.12. Cerbios-Pharma
22.12.1. Company Snapshot
22.12.2. Interview Transcript: Vitor Sousa (Business Development Manager)
22.13. Catalent Pharma Solutions
22.13.1. Company Snapshot
22.13.2. Interview Transcript: Jennifer L. Mitcham (Director, Business Development and Stacy McDonald, ex-Group Product Manager)
22.14. Lonza
22.14.1. Company Snapshot
22.14.2. Interview Transcript: Laurent Ducry (ex-Head of Bioconjugates Commercial Development)
22.15. Piramal Pharma Solutions
22.15.1. Company Snapshot
22.15.2. Interview Transcript: Mark Wright (ex-Site Head)
22.16. Ajinomoto Bio-Pharma Services
22.16.1. Company Snapshot
22.16.2. Interview Transcript: Zhala Tawfiq (Associate General Manager)
22.17. Interview Transcript: Anonymous (Director, Business Development, Leading CMO)
22.18. Interview Transcript: Anonymous (Chief Executive Officer, Leading CMO)
23. APPENDIX I: TABULATED DATA
24. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS
1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4 Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Key Components of Antibody Drug Conjugates (ADCs)
3.2.1. Antibody
3.2.2. Cytotoxin
3.2.3. Linker
3.3. ADC Manufacturing
3.3.1. Key Steps
3.3.2. Technical Challenges
3.3.3. Need for Outsourcing
3.4. Challenges Associated with Supply Chain and Method Transfer
3.4.1. Growing Demand for One-Stop-Shops and Integrated Service Providers
3.5. Key Considerations While Selecting a CMO Partner
3.6. Future Perspective
4. ADC CONTRACT MANUFACTURING SERVICE PROVIDERS: MARKET LANDSCAPE
4.1. Chapter Overview
4.2. ADC Contract Manufacturing Service Providers: Overall Market Landscape
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis By Company Size
4.2.3. Analysis by Location of Headquarters
4.2.4. Analysis by Service(s) Offered
4.2.5. Analysis by Other ADC Service(s) Offered
4.2.6. Analysis by Scale of Operation
4.2.7. Analysis by Location of Dedicated Manufacturing Facility
4.3. List of Antibody Contract Manufacturing Service Providers
4.4. List of HPAPI / Cytotoxic Payload Contract Manufacturing Service Providers
4.5. List of Biologics Fill / Finish Service Providers
5. COMPANY PROFILES
5.1. Chapter Overview
5.2. MabPlex
5.2.1. Company Overview
5.2.2. ADC Offerings
5.2.3. Manufacturing Facilities
5.2.4. Recent Development and Future Outlook
5.3. AbbVie Contract Manufacturing
5.3.1. Company Overview
5.3.2. ADC Offerings
5.3.3. Manufacturing Facilities
5.3.4. Recent Development and Future Outlook
5.4. Lonza
5.4.1. Company Overview
5.4.2. Financial Information
5.4.3. ADC Offerings
5.4.4. Manufacturing Facilities
5.4.5. Recent Development and Future Outlook
5.5. Catalent Pharma Solutions
5.5.1. Company Overview
5.5.2. Financial Information
5.5.3. ADC Offerings
5.5.4. Manufacturing Facilities
5.5.5. Recent Development and Future Outlook
5.6. Goodwin Biotechnology
5.6.1. Company Overview
5.6.2. ADC Offerings
5.6.3. Manufacturing Facilities
5.6.4. Recent Development and Future Outlook
5.7. Piramal Pharma Solutions
5.7.1. Company Overview
5.7.2. ADC Offerings
5.7.3. Manufacturing Facilities
5.7.4. Recent Development and Future Outlook
5.8. Millipore Sigma
5.8.1. Company Overview
5.8.2. ADC Offerings
5.8.3. Manufacturing Facilities
5.8.4. Recent Development and Future Outlook
5.9. Abzena
5.9.1. Company Overview
5.9.2. ADC Offerings
5.9.3. Manufacturing Facilities
5.9.4. Recent Development and Future Outlook
5.10. CARBOGEN AMCIS
5.10.1. Company Overview
5.10.2. ADC Offerings
5.10.3. Manufacturing Facilities
5.10.4. Recent Development and Future Outlook
5.11. WuXi Biologics
5.11.1. Company Overview
5.11.2. Financial Information
5.11.3. ADC Offerings
5.11.4. Manufacturing Facilities
5.11.5. Recent Development and Future Outlook
5.12. Cerbios-Pharma
5.12.1. Company Overview
5.12.2. ADC Offerings
5.12.3. Manufacturing Facilities
5.12.4. Recent Development and Future Outlook
5.13. Formosa Laboratories
5.13.1. Company Overview
5.13.2. ADC Offerings
5.13.3. Manufacturing Facilities
5.13.4. Recent Development and Future Outlook
5.14. Creative Biolabs
5.14.1. Company Overview
5.14.2. ADC Offerings
5.14.3. Manufacturing Facilities
5.14.4. Recent Development and Future Outlook
5.15. Novasep
5.15.1. Company Overview
5.15.2. ADC Offerings
5.15.3. Manufacturing Facilities
5.15.4. Recent Development and Future Outlook
5.16. Sterling Pharma Solutions
5.16.1. Company Overview
5.16.2. ADC Offerings
5.16.3. Manufacturing Facilities
5.16.4. Recent Development and Future Outlook
6. COMPANY COMPETITIVENESS ANALYSIS
6.1. Chapter Overview
6.2. Methodology and Key Parameters
6.3. ADC Contract Manufacturing Service Providers: Company Competitiveness Analysis
6.3.1. ADC Contract Manufacturing Service Providers based in North America
6.3.2. ADC Contract Manufacturing Service Providers based in Europe
6.3.3. ADC Contract Manufacturing Service Providers based in Asia-Pacific
7. ADC CONTRACT MANUFACTURING SERVICE PROVIDERS: RECENT EXPANSIONS
7.1. Chapter Overview
7.2. ADC Contract Manufacturing Service Providers: Recent Expansions
7.2.1. Analysis by Year of Expansion
7.2.2. Analysis by Type of Expansion
7.2.3. Analysis by Type of Service(s) Offered
7.2.4. Analysis by Location of Expanded Facility
7.2.5. Analysis by Scale of Operation
7.2.6. Most Active Players: Analysis by Number of Expansions
8. ADC CONTRACT MANUFACTURING SERVICE PROVIDERS: PARTNERSHIPS AND COLLABORATIONS
8.1. Chapter Overview
8.2. Partnership Models
8.3. ADC Contract Manufacturing Service Providers: List of Partnerships and Collaborations
8.3.1. Analysis by Year of Partnership
8.3.2. Analysis by Type of Partnership
8.3.3. Analysis by Type of Service(s) Provided
8.3.4. Analysis by Scale of Operation
8.3.5. Most Active Players: Analysis by Number of Partnerships
8.3.6. Regional Analysis
8.3.6.1. Local and International Agreements
8.3.6.2. Intercontinental and Intracontinental Agreements
9. MAKE VERSUS BUY DECISION MAKING
9.1. Chapter Overview
9.2. Assumptions and Key Parameters
9.2.1. Scenario
9.2.2. Scenario
9.2.3. Scenario
9.2.4. Scenario
9.3. Concluding Remarks
10. VALUE CHAIN ANALYSIS
10.1. Chapter Overview
10.2. ADC Development Value Chain
10.3. Cost Distribution Across the Value Chain
10.3.1. Cost Associated with Antibody Manufacturing
10.3.2. Cost Associated with Payload and Linker Manufacturing
10.3.3. Cost Associated with Conjugation
10.3.4. Cost Associated with Fill / Finish
11. ADC MANUFACTURING: CAPACITY ANALYSIS
11.1. Chapter Overview
11.2. Key Assumptions and Methodology
11.3. ADC Manufacturing: Global Installed Capacity
11.3.1. Analysis by Company Size
11.3.2. Analysis by Location of Headquarters
11.3.3. Analysis by Location of Manufacturing Facilities
11.3.3.1 Analysis by Country
11.3.3.2. Analysis by Continent
11.3.4. Analysis by Key Players
12. ADC THERAPEUTICS: MARKET OVERVIEW
12.1. Chapter Overview
12.2. List of ADC Therapeutics
12.2.1. Analysis by Phase of Development
12.2.2. Analysis by Target Disease Indication
12.2.3. Analysis by Target Antigen
12.2.4. Analysis by Antibody Isotype
12.2.5. Analysis by Type of Linker
12.2.6. Analysis by Payload / Warhead
12.2.7. Analysis by Type of Payload
12.3. Antibody Drug Conjugates: List of Therapy Developers
12.3.1. Analysis by Company Size and Location of Headquarters
12.3.2. List of Discontinued Drugs
13. NOVEL ADC CONJUGATION TECHNOLOGY PLATFORMS
13.1. Chapter Overview
13.2. First Generation ADC Technologies
13.3. Second Generation ADC Technologies
13.3.1. Cysteine and Selenocysteine Engineering
13.3.2. Unnatural Amino Acid Engineering
13.3.3. Amino-Terminal Serine Engineering
13.4. Third Generation ADC Technologies
13.4.1. Enzyme-Assisted Ligation Approaches
13.4.2. Glycan Remodeling Approaches
13.4.3. Ligation at Fab Nucleotide-Binding Site
13.4.4. Cysteine Rebridging
13.4.5. Avoiding or Limiting Retro-Michael Drug Deconjugation
13.5. Other Emerging ADC Technologies
13.6. Evolutionary Analysis
14. CLINICAL TRIALS ANALYSIS
14.1. Chapter Overview
14.2. Scope and Methodology
14.3. ADC Therapeutics: Clinical Trial Analysis
14.3.1. Analysis by Trial Registration Year
14.3.2. Analysis by Trial Phase
14.3.3. Analysis by Trial Status
14.3.4. Analysis by Type of Payload
14.3.5. Analysis by Type of Linker
14.3.6. Analysis by Antibody Isotope
14.3.7. Most Active Players: Analysis by Number of Clinical Trials
14.3.8. Most Active Sponsors: Analysis by Number of Clinical Trials
14.3.9. Analysis by Number of Trials and Geography
14.3.10. Analysis by Number of Trials, Trial Status and Geography
14.3.11. Analysis by Enrolled Patient Population, Trial Status and Geography
14.4. ADC Therapeutics: Analysis by Antibody Isotope and Geography
14.4.1. IgG based Molecules
14.4.1.1. Analysis by Phase of Development and Geography
14.4.1.2. Analysis by Trial Status and Geography
14.4.1.3. Analysis by Enrolled Patient Population and Geography
14.4.2. IgG1 based Molecules
14.4.2.1. Analysis by Phase of Development and Geography
14.4.2.2. Analysis by Trial Status and Geography
14.4.2.3. Analysis by Enrolled Patient Population and Geography
14.4.3. IgG4 based Molecules
14.4.3.1. Analysis by Phase of Development and Geography
14.4.3.2. Analysis by Trial Status and Geography
14.4.3.3. Analysis by Enrolled Patient Population and Geography
14.4.4. Other Antibody Isotope based Molecules
14.4.4.1. Analysis by Phase of Development and Geography
14.4.4.2. Analysis by Trial Status and Geography
14.4.4.3. Analysis by Enrolled Patient Population and Geography
14.5. ADC Therapeutics: Analysis by Type of Payload and Geography
14.5.1. Auristatin based Molecules
14.5.1.1. Analysis by Phase of Development and Geography
14.5.1.2. Analysis by Trial Status and Geography
14.5.1.3. Analysis by Enrolled Patient Population and Geography
14.5.2. Calicheamicin (Ozogamicin) based Molecules
14.5.2.1. Analysis by Phase of Development and Geography
14.5.2.2. Analysis by Trial Status and Geography
14.5.2.3. Analysis by Enrolled Patient Population and Geography
14.5.3. Maytansine based Molecules
14.5.3.1. Analysis by Phase of Development and Geography
14.5.3.2. Analysis by Geography and Trial Status and Geography
14.5.3.3. Analysis by Enrolled Patient Population and Geography
14.5.4. Exatecan based Molecules
14.5.4.1. Analysis by Phase of Development and Geography
14.5.4.2. Analysis by Trial Status and Geography
14.5.4.3. Analysis by Enrolled Patient Population and Geography
14.5.5. Maytansinoid based Molecules
14.5.5.1. Analysis by Phase of Development and Geography
14.5.5.2. Analysis by Geography and Trial Status
14.5.5.3. Analysis by Geography and Enrolled Patient Population
14.5.2. Camptothecin based Molecules
14.5.6.1. Analysis by Phase of Development and Geography
14.5.6.2. Analysis by Trial Status and Geography
14.5.6.3. Analysis by Enrolled Patient Population and Geography
14.5.2. Other Payload based Molecules
14.5.7.1. Analysis by Phase of Development and Geography
14.5.7.2. Analysis by Trial Status and Geography
14.5.7.3. Analysis by Enrolled Patient Population and Geography
14.6. ADC Therapeutics: Analysis by Type of Linker and Geography
14.6.1. VC based Molecules
14.6.1.1. Analysis by Phase of Development and Geography
14.6.1.2. Analysis by Trial Status and Geography
14.6.1.3. Analysis by Enrolled Patient Population and Geography
14.6.2. Peptide Linker based Molecules
14.6.2.1. Analysis by Phase of Development and Geography
14.6.2.2. Analysis by Trial Status and Geography
14.6.2.3. Analysis by Enrolled Patient Population and Geography
14.6.3. Mc-Val-Cit-PABC based Molecules
14.6.3.1. Analysis by Phase of Development and Geography
14.6.3.2. Analysis by Trial Status and Geography
14.6.3.3. Analysis by Enrolled Patient Population and Geography
14.6.4. AcBut based Molecules
14.6.4.1. Analysis by Phase of Development and Geography
14.6.4.2. Analysis by Trial Status and Geography
14.6.4.3. Analysis by Enrolled Patient Population and Geography
14.6.5. SMCC based Molecules
14.6.5.1. Analysis by Phase of Development and Geography
14.6.5.2. Analysis by Trial Status and Geography
14.6.5.3. Analysis by Enrolled Patient Population and Geography
14.6.6. SPDB based Molecules
14.6.6.1. Analysis by Phase of Development and Geography
14.6.6.2. Analysis by Trial Status and Geography
14.6.6.3. Analysis by Enrolled Patient Population and Geography
14.6.7. Others Linker based Molecules
14.6.7.1. Analysis by Phase of Development and Geography
14.6.7.2. Analysis by Trial Status and Geography
14.6.7.3. Analysis by Enrolled Patient Population and Geography
15. LIKELY PARTNER ANALYSIS
15.1. Chapter Overview
15.2. Scope and Methodology
15.3. Key Potential Strategic Partners for ADC Therapeutics Developers
15.3.1. Likely Partner Opportunities in North America
15.3.2. Likely Partner Opportunities in Europe
15.3.3. Likely Partner Opportunities in Asia-Pacific
16. ADC THERAPEUTICS: DEMAND ANALYSIS
16.1. Chapter Overview
16.2. Key Assumptions and Methodology
16.3. ADC Therapeutics: Overall Annual Demand
16.3.1. ADC Therapeutics: Annual Commercial Demand
16.3.1.1. Analysis by Type of Cancer
16.3.1.2. Analysis by Antibody Origin
16.3.1.3. Analysis by Antibody Isotype
16.3.1.4. Analysis by Type of Payload
16.3.1.5. Analysis by Type of Linker
16.3.1.6 Analysis by Key Geographical Regions
16.3.2. ADC Therapeutics: Annual Clinical Demand
16.3.2.1. Analysis by Phase of Development
16.3.2.2. Analysis by Type of Cancer
16.3.2.3. Analysis by Antibody Origin
16.3.2.4. Analysis by Antibody Isotype
16.3.2.5. Analysis by Type of Payload
16.3.2.6. Analysis by Type of Linker
16.3.2.7. Analysis by Key Geographical Regions
16.4. ADC Therapeutics: Demand and Supply Analysis
17. REGIONAL CAPABILITY ASSESSMENT ANALYSIS
17.1. Chapter Overview
17.2. Assumptions and Key Parameters
17.3. Regional Capability Assessment in North America
17.4. Regional Capability Assessment in Europe
17.5. Regional Capability Assessment in Asia-Pacific
17.6. Concluding Remarks
18. ATTRACTIVENESS COMPETETIVENESS MATRIX
18.1. Chapter Overview
18.2. AC Matrix: An Overview
18.2.1. Strong Business Segments
18.2.2. Average Business Segments
18.2.3. Weak Business Segments
18.3. AC Matrix: Analytical Methodology
18.4. AC Matrix: Overall ADC Contract Manufacturing Market Scenario
18.4.1. AC Matrix: ADC Contract Manufacturing Scenario for Type of Service(s) Offered
18.4.2. AC Matrix: ADC Contract Manufacturing Scenario for Key Geographies
19. MARKET SIZING AND OPPORTUNITY ANALYSIS
19.1. Chapter Overview
19.2. Input Data and Key Assumptions
19.3. Forecast Methodology
19.4. Global ADC Therapeutics Market, 2022-2035
19.5. Global ADC Contract Manufacturing Market, 2022-2035
19.5.1. ADC Contract Manufacturing Market: Analysis by Type of Component Manufacturing, 2022-2035
19.5.2. ADC Contract Manufacturing Market: Analysis by Phase of Development, 2022-2035
19.6. ADC Contract Manufacturing Market for Commercial Products, 2022-2035
19.6.1. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Component Manufacturing, 2022-2035
19.6.1.1. ADC Contract Manufacturing Market for Commercial Products, Analysis by Antibody Origin, 2022-2035
19.6.1.2. ADC Contract Manufacturing Market for Commercial Products, Analysis by Antibody Isotype, 2022-2035
19.6.1.3. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Payload, 2022-2035
19.6.1.4. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Linker, 2022-2035
19.6.2. ADC Contract Manufacturing Market for Commercial Products, Analysis by Type of Cancer, 2022-2035
19.6.3. ADC Contract Manufacturing Market for Commercial Products, Analysis by Key Geographical Regions, 2022-2035
19.6.3.1. ADC Contract Manufacturing Market for Commercial Products in North America, 2022-2035
19.6.3.2. ADC Contract Manufacturing Market for Commercial Products in EU5, 2022-2035
19.6.3.3. ADC Contract Manufacturing Market for Commercial Products in Rest of the World, 2022-2035
19.7. ADC Contract Manufacturing Market for Clinical Products, 2022-2035
19.7.1. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Component Manufacturing, 2022-2035
19.7.1.1. ADC Contract Manufacturing Market for Clinical Products, Analysis by Antibody Origin, 2022-2035
19.7.1.2. ADC Contract Manufacturing Market for Clinical Products, Analysis by Antibody Isotype, 2022-2035
19.7.1.3. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Payload, 2022-2035
19.7.1.4. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Linker, 2022-2035
19.7.2. ADC Contract Manufacturing Market for Clinical Products, Analysis by Type of Cancer, 2022-2035
19.7.3. ADC Contract Manufacturing Market for Clinical Products, Analysis by Key Geographical Regions, 2022-2035
19.7.3.1. ADC Contract Manufacturing Market for Clinical Products in North America, 2022-2035
19.7.3.2. ADC Contract Manufacturing Market for Clinical Products in Europe, 2022-2035
19.7.3.3. ADC Contract Manufacturing Market for Clinical Products in Asia-Pacific, 2022-2035
19.7.3.4. ADC Contract Manufacturing Market for Clinical Products in MENA, 2022-2035
19.7.3.5. ADC Contract Manufacturing Market for Clinical Products in Latin America, 2022-2035
19.7.3.6. ADC Contract Manufacturing Market for Clinical Products in Rest of the World, 2022-2035
20. SWOT ANALYSIS
20.1. Chapter Overview
20.2. Strengths
20.3. Weaknesses
20.4. Opportunities
20.5. Threats
20.6. Comparison of SWOT Factors
21. CONCLUDING REMARKS
22. INTERVIEW TRANSCRIPTS
22.1. Chapter Overview
22.2. BSP Pharmaceuticals
22.2.1. Company Snapshot
22.2.2. Interview Transcript: Aldo Braca (Chief Executive Officer and Giorgio Salciarini, Technical Business Development Manager)
22.3. Oxford BioTherapeutics
22.3.1. Company Snapshot
22.3.2. Interview Transcript: Christian Rohlff (Chief Executive Officer & Founder)
22.4. Abzena
22.4.1. Company Snapshot
22.4.2. Interview Transcript: ex-John Burt (Chief Executive Officer)
22.5. Syndivia
22.5.1. Company Snapshot
22.5.2. Interview Transcript: Sasha Koniev (Chief Executive Officer & Co-Founder)
22.6. Cerbios-Pharma
22.6.1. Company Snapshot
22.6.2. Interview Transcript: Denis Angioletti (Chief Commercial Officer)
22.7. NBE-Therapeutics
22.7.1. Company Snapshot
22.7.2. Interview Transcript: Wouter Verhoeven (Chief Business Officer)
22.8. Eisai
22.8.1. Company Snapshot
22.8.2. Interview Transcript: Toshimitsu Uenaka (Executive Director and Takashi Owa, Chief Innovation Officer)
22.9. Synaffix
22.9.1. Company Snapshot
22.9.2. Interview Transcript: Anthony DeBoer (Director, Business Development)
22.10. Pierre Fabre
22.10.1. Company Snapshot
22.10.2. Interview Transcript: ex-Christian Bailly (Director of CDMO)
22.11. Goodwin Biotechnology
22.11.1. Company Snapshot
22.11.2. Interview Transcript: David Cunningham (Director Corporate Development)
22.12. Cerbios-Pharma
22.12.1. Company Snapshot
22.12.2. Interview Transcript: Vitor Sousa (Business Development Manager)
22.13. Catalent Pharma Solutions
22.13.1. Company Snapshot
22.13.2. Interview Transcript: Jennifer L. Mitcham (Director, Business Development and Stacy McDonald, ex-Group Product Manager)
22.14. Lonza
22.14.1. Company Snapshot
22.14.2. Interview Transcript: Laurent Ducry (ex-Head of Bioconjugates Commercial Development)
22.15. Piramal Pharma Solutions
22.15.1. Company Snapshot
22.15.2. Interview Transcript: Mark Wright (ex-Site Head)
22.16. Ajinomoto Bio-Pharma Services
22.16.1. Company Snapshot
22.16.2. Interview Transcript: Zhala Tawfiq (Associate General Manager)
22.17. Interview Transcript: Anonymous (Director, Business Development, Leading CMO)
22.18. Interview Transcript: Anonymous (Chief Executive Officer, Leading CMO)
23. APPENDIX I: TABULATED DATA
24. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS
