Global PNH and aHUS Market Growth (Status and Outlook) 2025-2031

January 2025 | 80 pages | ID: GBF344F272DDEN
LP Information

Abstracts

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The global PNH and aHUS market size is predicted to grow from US$ 5699 million in 2025 to US$ 8382 million in 2031; it is expected to grow at a CAGR of 6.6% from 2025 to 2031.

PNH and aHUS, both are extremely rare and genetic diseases. Due to PNH, destruction of red blood cells of a person occurs quite sooner than it should. It is an acquired hematopoietic stem cell disorder. Hematopoietic stem cells are developed in bone marrow and eventually turn into red blood cells, white blood cells and platelets. A person with PNH has some defected hematopoietic cells which create defective red blood cells. These defective cells are highly susceptible to premature destruction by the complement system. aHUS is a disorders in which blood clots are formed in small blood vessels throughout the body. TMA can lead to heart stroke, attack, kidney failure and death.

United States is the largest consumption place, with a consumption market share nearly 52.1% in 2019. Following United States, Europe is the second largest consumption place with the consumption market share of 26.2%.

LPI (LP Information)' newest research report, the “PNH and aHUS Industry Forecast” looks at past sales and reviews total world PNH and aHUS sales in 2024, providing a comprehensive analysis by region and market sector of projected PNH and aHUS sales for 2025 through 2031. With PNH and aHUS sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world PNH and aHUS industry.

This Insight Report provides a comprehensive analysis of the global PNH and aHUS landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyses the strategies of leading global companies with a focus on PNH and aHUS portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global PNH and aHUS market.

This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for PNH and aHUS and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global PNH and aHUS.

This report presents a comprehensive overview, market shares, and growth opportunities of PNH and aHUS market by product type, application, key players and key regions and countries.

Segmentation by Type:

• Soliris
• Ultomiris

Segmentation by Application:

• PNH
• aHUS

This report also splits the market by region:

• Americas
• United States
• Canada
• Mexico
• Brazil
• APAC
• China
• Japan
• Korea
• Southeast Asia
• India
• Australia
• Europe
• Germany
• France
• UK
• Italy
• Russia
• Middle East & Africa
• Egypt
• South Africa
• Israel
• Turkey
• GCC Countries

The below companies that are profiled have been selected based on inputs gathered from primary experts and analyzing the company's coverage, product portfolio, its market penetration.

• Alexion Pharmaceuticals
• Alnylam Pharmaceuticals
• Omeros Corporation

Contents

1 SCOPE OF THE REPORT

1.1 Market Introduction
1.2 Years Considered
1.3 Research Objectives
1.4 Market Research Methodology
1.5 Research Process and Data Source
1.6 Economic Indicators
1.7 Currency Considered
1.8 Market Estimation Caveats

2 EXECUTIVE SUMMARY

2.1 World Market Overview
  2.1.1 Global PNH and aHUS Market Size (2020-2031)
  2.1.2 PNH and aHUS Market Size CAGR by Region (2020 VS 2024 VS 2031)
  2.1.3 World Current & Future Analysis for PNH and aHUS by Country/Region (2020, 2024 & 2031)
2.2 PNH and aHUS Segment by Type
  2.2.1 Soliris
  2.2.2 Ultomiris
2.3 PNH and aHUS Market Size by Type
  2.3.1 PNH and aHUS Market Size CAGR by Type (2020 VS 2024 VS 2031)
  2.3.2 Global PNH and aHUS Market Size Market Share by Type (2020-2025)
2.4 PNH and aHUS Segment by Application
  2.4.1 PNH
  2.4.2 aHUS
2.5 PNH and aHUS Market Size by Application
  2.5.1 PNH and aHUS Market Size CAGR by Application (2020 VS 2024 VS 2031)
  2.5.2 Global PNH and aHUS Market Size Market Share by Application (2020-2025)

3 PNH AND AHUS MARKET SIZE BY PLAYER

3.1 PNH and aHUS Market Size Market Share by Player
  3.1.1 Global PNH and aHUS Revenue by Player (2020-2025)
  3.1.2 Global PNH and aHUS Revenue Market Share by Player (2020-2025)
3.2 Global PNH and aHUS Key Players Head office and Products Offered
3.3 Market Concentration Rate Analysis
  3.3.1 Competition Landscape Analysis
  3.3.2 Concentration Ratio (CR3, CR5 and CR10) & (2023-2025)
3.4 New Products and Potential Entrants
3.5 Mergers & Acquisitions, Expansion

4 PNH AND AHUS BY REGION

4.1 PNH and aHUS Market Size by Region (2020-2025)
4.2 Global PNH and aHUS Annual Revenue by Country/Region (2020-2025)
4.3 Americas PNH and aHUS Market Size Growth (2020-2025)
4.4 APAC PNH and aHUS Market Size Growth (2020-2025)
4.5 Europe PNH and aHUS Market Size Growth (2020-2025)
4.6 Middle East & Africa PNH and aHUS Market Size Growth (2020-2025)

5 AMERICAS

5.1 Americas PNH and aHUS Market Size by Country (2020-2025)
5.2 Americas PNH and aHUS Market Size by Type (2020-2025)
5.3 Americas PNH and aHUS Market Size by Application (2020-2025)
5.4 United States
5.5 Canada
5.6 Mexico
5.7 Brazil

6 APAC

6.1 APAC PNH and aHUS Market Size by Region (2020-2025)
6.2 APAC PNH and aHUS Market Size by Type (2020-2025)
6.3 APAC PNH and aHUS Market Size by Application (2020-2025)
6.4 China
6.5 Japan
6.6 South Korea
6.7 Southeast Asia
6.8 India
6.9 Australia

7 EUROPE

7.1 Europe PNH and aHUS Market Size by Country (2020-2025)
7.2 Europe PNH and aHUS Market Size by Type (2020-2025)
7.3 Europe PNH and aHUS Market Size by Application (2020-2025)
7.4 Germany
7.5 France
7.6 UK
7.7 Italy
7.8 Russia

8 MIDDLE EAST & AFRICA

8.1 Middle East & Africa PNH and aHUS by Region (2020-2025)
8.2 Middle East & Africa PNH and aHUS Market Size by Type (2020-2025)
8.3 Middle East & Africa PNH and aHUS Market Size by Application (2020-2025)
8.4 Egypt
8.5 South Africa
8.6 Israel
8.7 Turkey
8.8 GCC Countries

9 MARKET DRIVERS, CHALLENGES AND TRENDS

9.1 Market Drivers & Growth Opportunities
9.2 Market Challenges & Risks
9.3 Industry Trends

10 GLOBAL PNH AND AHUS MARKET FORECAST

10.1 Global PNH and aHUS Forecast by Region (2026-2031)
  10.1.1 Global PNH and aHUS Forecast by Region (2026-2031)
  10.1.2 Americas PNH and aHUS Forecast
  10.1.3 APAC PNH and aHUS Forecast
  10.1.4 Europe PNH and aHUS Forecast
  10.1.5 Middle East & Africa PNH and aHUS Forecast
10.2 Americas PNH and aHUS Forecast by Country (2026-2031)
  10.2.1 United States Market PNH and aHUS Forecast
  10.2.2 Canada Market PNH and aHUS Forecast
  10.2.3 Mexico Market PNH and aHUS Forecast
  10.2.4 Brazil Market PNH and aHUS Forecast
10.3 APAC PNH and aHUS Forecast by Region (2026-2031)
  10.3.1 China PNH and aHUS Market Forecast
  10.3.2 Japan Market PNH and aHUS Forecast
  10.3.3 Korea Market PNH and aHUS Forecast
  10.3.4 Southeast Asia Market PNH and aHUS Forecast
  10.3.5 India Market PNH and aHUS Forecast
  10.3.6 Australia Market PNH and aHUS Forecast
10.4 Europe PNH and aHUS Forecast by Country (2026-2031)
  10.4.1 Germany Market PNH and aHUS Forecast
  10.4.2 France Market PNH and aHUS Forecast
  10.4.3 UK Market PNH and aHUS Forecast
  10.4.4 Italy Market PNH and aHUS Forecast
  10.4.5 Russia Market PNH and aHUS Forecast
10.5 Middle East & Africa PNH and aHUS Forecast by Region (2026-2031)
  10.5.1 Egypt Market PNH and aHUS Forecast
  10.5.2 South Africa Market PNH and aHUS Forecast
  10.5.3 Israel Market PNH and aHUS Forecast
  10.5.4 Turkey Market PNH and aHUS Forecast
10.6 Global PNH and aHUS Forecast by Type (2026-2031)
10.7 Global PNH and aHUS Forecast by Application (2026-2031)
  10.7.1 GCC Countries Market PNH and aHUS Forecast

11 KEY PLAYERS ANALYSIS

11.1 Alexion Pharmaceuticals
  11.1.1 Alexion Pharmaceuticals Company Information
  11.1.2 Alexion Pharmaceuticals PNH and aHUS Product Offered
  11.1.3 Alexion Pharmaceuticals PNH and aHUS Revenue, Gross Margin and Market Share (2020-2025)
  11.1.4 Alexion Pharmaceuticals Main Business Overview
  11.1.5 Alexion Pharmaceuticals Latest Developments
11.2 Alnylam Pharmaceuticals
  11.2.1 Alnylam Pharmaceuticals Company Information
  11.2.2 Alnylam Pharmaceuticals PNH and aHUS Product Offered
  11.2.3 Alnylam Pharmaceuticals PNH and aHUS Revenue, Gross Margin and Market Share (2020-2025)
  11.2.4 Alnylam Pharmaceuticals Main Business Overview
  11.2.5 Alnylam Pharmaceuticals Latest Developments
11.3 Omeros Corporation
  11.3.1 Omeros Corporation Company Information
  11.3.2 Omeros Corporation PNH and aHUS Product Offered
  11.3.3 Omeros Corporation PNH and aHUS Revenue, Gross Margin and Market Share (2020-2025)
  11.3.4 Omeros Corporation Main Business Overview
  11.3.5 Omeros Corporation Latest Developments

12 RESEARCH FINDINGS AND CONCLUSION


LIST OFTABLES

Table 1. PNH and aHUS Market Size CAGR by Region (2020 VS 2024 VS 2031) & ($ millions)
Table 2. PNH and aHUS Annual Sales CAGR by Country/Region (2020, 2024 & 2031) & ($ millions)
Table 3. Major Players of Soliris
Table 4. Major Players of Ultomiris
Table 5. PNH and aHUS Market Size CAGR byType (2020 VS 2024 VS 2031) & ($ millions)
Table 6. Global PNH and aHUS Market Size byType (2020-2025) & ($ millions)
Table 7. Global PNH and aHUS Market Size Market Share byType (2020-2025)
Table 8. PNH and aHUS Market Size CAGR by Application (2020 VS 2024 VS 2031) & ($ millions)
Table 9. Global PNH and aHUS Market Size by Application (2020-2025) & ($ millions)
Table 10. Global PNH and aHUS Market Size Market Share by Application (2020-2025)
Table 11. Global PNH and aHUS Revenue by Player (2020-2025) & ($ millions)
Table 12. Global PNH and aHUS Revenue Market Share by Player (2020-2025)
Table 13. PNH and aHUS Key Players Head office and Products Offered
Table 14. PNH and aHUS Concentration Ratio (CR3, CR5 and CR10) & (2023-2025)
Table 15. New Products and Potential Entrants
Table 16. Mergers & Acquisitions, Expansion
Table 17. Global PNH and aHUS Market Size by Region (2020-2025) & ($ millions)
Table 18. Global PNH and aHUS Market Size Market Share by Region (2020-2025)
Table 19. Global PNH and aHUS Revenue by Country/Region (2020-2025) & ($ millions)
Table 20. Global PNH and aHUS Revenue Market Share by Country/Region (2020-2025)
Table 21. Americas PNH and aHUS Market Size by Country (2020-2025) & ($ millions)
Table 22. Americas PNH and aHUS Market Size Market Share by Country (2020-2025)
Table 23. Americas PNH and aHUS Market Size byType (2020-2025) & ($ millions)
Table 24. Americas PNH and aHUS Market Size Market Share byType (2020-2025)
Table 25. Americas PNH and aHUS Market Size by Application (2020-2025) & ($ millions)
Table 26. Americas PNH and aHUS Market Size Market Share by Application (2020-2025)
Table 27. APAC PNH and aHUS Market Size by Region (2020-2025) & ($ millions)
Table 28. APAC PNH and aHUS Market Size Market Share by Region (2020-2025)
Table 29. APAC PNH and aHUS Market Size byType (2020-2025) & ($ millions)
Table 30. APAC PNH and aHUS Market Size by Application (2020-2025) & ($ millions)
Table 31. Europe PNH and aHUS Market Size by Country (2020-2025) & ($ millions)
Table 32. Europe PNH and aHUS Market Size Market Share by Country (2020-2025)
Table 33. Europe PNH and aHUS Market Size byType (2020-2025) & ($ millions)
Table 34. Europe PNH and aHUS Market Size by Application (2020-2025) & ($ millions)
Table 35. Middle East & Africa PNH and aHUS Market Size by Region (2020-2025) & ($ millions)
Table 36. Middle East & Africa PNH and aHUS Market Size byType (2020-2025) & ($ millions)
Table 37. Middle East & Africa PNH and aHUS Market Size by Application (2020-2025) & ($ millions)
Table 38. Key Market Drivers & Growth Opportunities of PNH and aHUS
Table 39. Key Market Challenges & Risks of PNH and aHUS
Table 40. Key IndustryTrends of PNH and aHUS
Table 41. Global PNH and aHUS Market SizeForecast by Region (2026-2031) & ($ millions)
Table 42. Global PNH and aHUS Market Size Market ShareForecast by Region (2026-2031)
Table 43. Global PNH and aHUS Market SizeForecast byType (2026-2031) & ($ millions)
Table 44. Global PNH and aHUS Market SizeForecast by Application (2026-2031) & ($ millions)
Table 45. Alexion Pharmaceuticals Details, CompanyType, PNH and aHUS Area Served and Its Competitors
Table 46. Alexion Pharmaceuticals PNH and aHUS Product Offered
Table 47. Alexion Pharmaceuticals PNH and aHUS Revenue ($ million), Gross Margin and Market Share (2020-2025)
Table 48. Alexion Pharmaceuticals Main Business
Table 49. Alexion Pharmaceuticals Latest Developments
Table 50. Alnylam Pharmaceuticals Details, CompanyType, PNH and aHUS Area Served and Its Competitors
Table 51. Alnylam Pharmaceuticals PNH and aHUS Product Offered
Table 52. Alnylam Pharmaceuticals PNH and aHUS Revenue ($ million), Gross Margin and Market Share (2020-2025)
Table 53. Alnylam Pharmaceuticals Main Business
Table 54. Alnylam Pharmaceuticals Latest Developments
Table 55. Omeros Corporation Details, CompanyType, PNH and aHUS Area Served and Its Competitors
Table 56. Omeros Corporation PNH and aHUS Product Offered
Table 57. Omeros Corporation PNH and aHUS Revenue ($ million), Gross Margin and Market Share (2020-2025)
Table 58. Omeros Corporation Main Business
Table 59. Omeros Corporation Latest Developments



LIST OFFIGURES

Figure 1. PNH and aHUS Report Years Considered
Figure 2. Research Objectives
Figure 3. Research Methodology
Figure 4. Research Process and Data Source
Figure 5. Global PNH and aHUS Market Size Growth Rate (2020-2031) ($ millions)
Figure 6. PNH and aHUS Sales by Geographic Region (2020, 2024 & 2031) & ($ millions)
Figure 7. PNH and aHUS Sales Market Share by Country/Region (2024)
Figure 8. PNH and aHUS Sales Market Share by Country/Region (2020, 2024 & 2031)
Figure 9. Global PNH and aHUS Market Size Market Share byType in 2024
Figure 10. PNH and aHUS in PNH
Figure 11. Global PNH and aHUS Market: PNH (2020-2025) & ($ millions)
Figure 12. PNH and aHUS in aHUS
Figure 13. Global PNH and aHUS Market: aHUS (2020-2025) & ($ millions)
Figure 14. Global PNH and aHUS Market Size Market Share by Application in 2024
Figure 15. Global PNH and aHUS Revenue Market Share by Player in 2024
Figure 16. Global PNH and aHUS Market Size Market Share by Region (2020-2025)
Figure 17. Americas PNH and aHUS Market Size 2020-2025 ($ millions)
Figure 18. APAC PNH and aHUS Market Size 2020-2025 ($ millions)
Figure 19. Europe PNH and aHUS Market Size 2020-2025 ($ millions)
Figure 20. Middle East & Africa PNH and aHUS Market Size 2020-2025 ($ millions)
Figure 21. Americas PNH and aHUS Value Market Share by Country in 2024
Figure 22. United States PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 23. Canada PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 24. Mexico PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 25. Brazil PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 26. APAC PNH and aHUS Market Size Market Share by Region in 2024
Figure 27. APAC PNH and aHUS Market Size Market Share byType (2020-2025)
Figure 28. APAC PNH and aHUS Market Size Market Share by Application (2020-2025)
Figure 29. China PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 30. Japan PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 31. South Korea PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 32. Southeast Asia PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 33. India PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 34. Australia PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 35. Europe PNH and aHUS Market Size Market Share by Country in 2024
Figure 36. Europe PNH and aHUS Market Size Market Share byType (2020-2025)
Figure 37. Europe PNH and aHUS Market Size Market Share by Application (2020-2025)
Figure 38. Germany PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 39.France PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 40. UK PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 41. Italy PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 42. Russia PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 43. Middle East & Africa PNH and aHUS Market Size Market Share by Region (2020-2025)
Figure 44. Middle East & Africa PNH and aHUS Market Size Market Share byType (2020-2025)
Figure 45. Middle East & Africa PNH and aHUS Market Size Market Share by Application (2020-2025)
Figure 46. Egypt PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 47. South Africa PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 48. Israel PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 49.Turkey PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 50. GCC Countries PNH and aHUS Market Size Growth 2020-2025 ($ millions)
Figure 51. Americas PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 52. APAC PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 53. Europe PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 54. Middle East & Africa PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 55. United States PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 56. Canada PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 57. Mexico PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 58. Brazil PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 59. China PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 60. Japan PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 61. Korea PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 62. Southeast Asia PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 63. India PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 64. Australia PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 65. Germany PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 66.France PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 67. UK PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 68. Italy PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 69. Russia PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 70. Egypt PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 71. South Africa PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 72. Israel PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 73.Turkey PNH and aHUS Market Size 2026-2031 ($ millions)
Figure 74. Global PNH and aHUS Market Size Market ShareForecast byType (2026-2031)
Figure 75. Global PNH and aHUS Market Size Market ShareForecast by Application (2026-2031)
Figure 76. GCC Countries PNH and aHUS Market Size 2026-2031 ($ millions)