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Urothelial Carcinoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 140 pages | ID: UA2351E91CBDEN
IMARC Group

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The 7 major urothelial carcinoma markets are expected to exhibit a CAGR of 12.34% during 2024-2034.

The urothelial carcinoma market has been comprehensively analyzed in IMARC's new report titled "Urothelial Carcinoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Urothelial carcinoma, often refer to as transitional cell carcinoma, is a type of cancer that primarily originates in the urothelial cells lining the urinary tract. It majorly affects the bladder but can also occur in other parts of the urinary system, such as the renal pelvis, ureters, urethra, etc. The most common symptom is hematuria, that is the presence of blood in the urine. Various other indications can include frequent urination, a persistent urge to urinate, pain or discomfort during urination, pelvic or back pain, etc. The diagnosis of urothelial carcinoma typically begins with a thorough medical history assessment and physical examination. Several diagnostic procedures, such as urine analysis to detect blood or abnormal cells and imaging tests like ultrasound, computed tomography (CT) scan, magnetic resonance imaging (MRI), etc., to visualize the urinary tract and identify any abnormalities, are performed. A biopsy of suspicious areas is crucial for a definitive diagnosis, as it allows for microscopic examination of the tissue to confirm the presence of the ailment and determine the stage and grade of the tumor. Numerous additional tests, including imaging of the upper urinary tract and pelvic lymph nodes, may be conducted to assess the spread of the cancer.


The increasing cases of genetic mutations that disrupt the normal functioning of genes, thereby leading to uncontrolled cell growth and tumor development, are primarily driving the urothelial carcinoma market. In addition to this, the rising prevalence of several associated risk factors, such as tobacco use, exposure to aromatic amines, previous history of bladder cancer, chronic urinary tract infections, long-standing bladder inflammation, etc., is also creating a positive outlook for the market. Moreover, the emerging popularity of external beam radiation therapy for treatment, since it utilizes high-energy beams to target cancer cells and relieve symptoms as well as improve the quality of life in patients, is further bolstering the market growth. Apart from this, the inflating application of immune checkpoint inhibitors, such as pembrolizumab, atezolizumab, nivolumab, etc., which harness the body's immune system to attack cancer cells and offer increased response rates and durable responses, as compared to traditional chemotherapy, is acting as another significant growth-inducing factor. Additionally, the escalating usage of minimally invasive surgical techniques, including robotic-assisted and laparoscopic surgeries, on account of their several associated benefits, such as reduced blood loss, shorter hospital stays, improved surgical precision, etc., is expected to drive the urothelial carcinoma market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the urothelial carcinoma market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for urothelial carcinoma and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the urothelial carcinoma market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the urothelial carcinoma market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the urothelial carcinoma market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current urothelial carcinoma marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the urothelial carcinoma market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the urothelial carcinoma market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the urothelial carcinoma market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of urothelial carcinoma across the seven major markets?
What is the number of prevalent cases (2018-2034) of urothelial carcinoma by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of urothelial carcinoma by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with urothelial carcinoma across the seven major markets?
What is the size of the urothelial carcinoma patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of urothelial carcinoma?
What will be the growth rate of patients across the seven major markets?

Urothelial Carcinoma: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for urothelial carcinoma drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the urothelial carcinoma market?
What are the key regulatory events related to the urothelial carcinoma market?
What is the structure of clinical trial landscape by status related to the urothelial carcinoma market?
What is the structure of clinical trial landscape by phase related to the urothelial carcinoma market?
What is the structure of clinical trial landscape by route of administration related to the urothelial carcinoma market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 UROTHELIAL CARCINOMA - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 UROTHELIAL CARCINOMA - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 UROTHELIAL CARCINOMA - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 UROTHELIAL CARCINOMA - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 UROTHELIAL CARCINOMA - UNMET NEEDS

10 UROTHELIAL CARCINOMA - KEY ENDPOINTS OF TREATMENT

11 UROTHELIAL CARCINOMA - MARKETED PRODUCTS

11.1 List of Urothelial Carcinoma Marketed Drugs Across the Top 7 Markets
  11.1.1 Balversa (Erdafitinib) - Janssen Pharmaceuticals
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Bavencio (Avelumab) - Merck KGaA
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
  11.1.3 Keytruda (Pembrolizumab) - Merck & Co
    11.1.3.1 Drug Overview
    11.1.3.2 Mechanism of Action
    11.1.3.3 Regulatory Status
    11.1.3.4 Clinical Trial Results
    11.1.3.5 Sales Across Major Markets
  11.1.4 Opdivo (Nivolumab) - Bristol-Myers Squibb/Ono Pharmaceuticals
    11.1.4.1 Drug Overview
    11.1.4.2 Mechanism of Action
    11.1.4.3 Regulatory Status
    11.1.4.4 Clinical Trial Results
    11.1.4.5 Sales Across Major Markets
  11.1.5 Tecentriq (Atezolizumab) - Genentech
    11.1.5.1 Drug Overview
    11.1.5.2 Mechanism of Action
    11.1.5.3 Regulatory Status
    11.1.5.4 Clinical Trial Results
    11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 UROTHELIAL CARCINOMA - PIPELINE DRUGS

12.1 List of Urothelial Carcinoma Pipeline Drugs Across the Top 7 Markets
  12.1.1 Disitamab vedotin - Seagen
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 IPI 549 - Infinity Pharmaceuticals
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 Evorpacept - ALX Oncology
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 MV NIS - Vyriad
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
  12.1.5 Enfortumab vedotin - Astellas Pharma/Seagen
    12.1.5.1 Drug Overview
    12.1.5.2 Mechanism of Action
    12.1.5.3 Clinical Trial Results
    12.1.5.4 Safety and Efficacy
    12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. UROTHELIAL CARCINOMA - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. UROTHELIAL CARCINOMA – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 UROTHELIAL CARCINOMA - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Urothelial Carcinoma - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Urothelial Carcinoma - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Urothelial Carcinoma - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Urothelial Carcinoma - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Urothelial Carcinoma - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Urothelial Carcinoma - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Urothelial Carcinoma - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Urothelial Carcinoma - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Urothelial Carcinoma - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Urothelial Carcinoma - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Urothelial Carcinoma - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Urothelial Carcinoma - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Urothelial Carcinoma - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Urothelial Carcinoma - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Urothelial Carcinoma - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Urothelial Carcinoma - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Urothelial Carcinoma - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Urothelial Carcinoma - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Urothelial Carcinoma - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Urothelial Carcinoma - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Urothelial Carcinoma - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Urothelial Carcinoma - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Urothelial Carcinoma - Access and Reimbursement Overview

16 UROTHELIAL CARCINOMA - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 UROTHELIAL CARCINOMA MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 UROTHELIAL CARCINOMA MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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